Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #wtNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_wtNotch.cls#wtNotch_versus_absentNotch |
Upregulated in class | absentNotch |
GeneSet | V$USF_02 |
Enrichment Score (ES) | -0.5416256 |
Normalized Enrichment Score (NES) | -1.6395575 |
Nominal p-value | 0.0 |
FDR q-value | 0.13393341 |
FWER p-Value | 0.267 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | CHD4 | 5420059 6130338 6380717 | 406 | 1.424 | -0.0022 | No | ||
2 | PTGES2 | 4210097 | 408 | 1.422 | 0.0175 | No | ||
3 | SESN3 | 110687 | 582 | 1.234 | 0.0252 | No | ||
4 | ZFYVE26 | 6860152 | 810 | 1.060 | 0.0276 | No | ||
5 | OPRS1 | 6130128 6290717 | 845 | 1.032 | 0.0401 | No | ||
6 | VPS16 | 430064 3390041 6860301 | 1113 | 0.893 | 0.0380 | No | ||
7 | CCAR1 | 3190092 | 1344 | 0.777 | 0.0363 | No | ||
8 | ATF4 | 730441 1740195 | 1813 | 0.593 | 0.0192 | No | ||
9 | COQ4 | 1660551 | 1833 | 0.585 | 0.0263 | No | ||
10 | PRPS1 | 6350129 | 2061 | 0.513 | 0.0211 | No | ||
11 | NDUFA7 | 5900722 | 2220 | 0.467 | 0.0190 | No | ||
12 | HIVEP1 | 3850632 | 2376 | 0.420 | 0.0164 | No | ||
13 | GTF2H1 | 2570746 2650148 | 2403 | 0.412 | 0.0207 | No | ||
14 | MRPL27 | 2060131 | 2609 | 0.363 | 0.0147 | No | ||
15 | ARPP-19 | 5700025 | 2671 | 0.350 | 0.0162 | No | ||
16 | BRDT | 3940102 | 2703 | 0.342 | 0.0193 | No | ||
17 | DHX35 | 1230440 | 2811 | 0.322 | 0.0180 | No | ||
18 | UROD | 2470494 | 2844 | 0.315 | 0.0206 | No | ||
19 | STC2 | 4920601 | 2899 | 0.306 | 0.0219 | No | ||
20 | DDIT3 | 780373 | 2986 | 0.290 | 0.0213 | No | ||
21 | MAP4K1 | 4060692 | 3032 | 0.284 | 0.0228 | No | ||
22 | GTF2A1 | 4120138 4920524 5390110 1230397 | 3090 | 0.274 | 0.0235 | No | ||
23 | ISGF3G | 3190131 7100142 | 3293 | 0.240 | 0.0159 | No | ||
24 | ATP6V1A | 6590242 | 3325 | 0.234 | 0.0175 | No | ||
25 | DUSP7 | 2940309 | 3538 | 0.207 | 0.0088 | No | ||
26 | HNRPA1 | 4670398 5050687 | 3753 | 0.184 | -0.0002 | No | ||
27 | ARMET | 5130670 | 3816 | 0.178 | -0.0011 | No | ||
28 | NFX1 | 450504 | 3877 | 0.172 | -0.0020 | No | ||
29 | DUSP8 | 6650039 | 3886 | 0.171 | -0.0000 | No | ||
30 | FEN1 | 1770541 | 4018 | 0.160 | -0.0049 | No | ||
31 | RPS2 | 1340647 | 4019 | 0.160 | -0.0027 | No | ||
32 | EGLN2 | 540086 | 4060 | 0.156 | -0.0027 | No | ||
33 | SLC39A5 | 2900100 4610440 | 4134 | 0.149 | -0.0046 | No | ||
34 | TESK2 | 6520524 | 4155 | 0.147 | -0.0036 | No | ||
35 | TAF6L | 1850056 | 4178 | 0.145 | -0.0028 | No | ||
36 | NEUROD1 | 3060619 | 4179 | 0.145 | -0.0008 | No | ||
37 | RFC1 | 1190673 | 4254 | 0.140 | -0.0029 | No | ||
38 | SOX10 | 6200538 | 4333 | 0.134 | -0.0052 | No | ||
39 | MDM1 | 510528 1780280 2680152 2690181 3060025 3120487 4210601 4540037 4610142 5290110 6400433 6480743 | 4445 | 0.127 | -0.0095 | No | ||
40 | RPS28 | 3830221 | 4490 | 0.124 | -0.0102 | No | ||
41 | HOXB7 | 4540706 4610358 | 4493 | 0.123 | -0.0086 | No | ||
42 | COPZ1 | 6940100 | 4494 | 0.123 | -0.0068 | No | ||
43 | SEMA3A | 1780064 | 4591 | 0.117 | -0.0104 | No | ||
44 | NRIP3 | 1340372 | 4783 | 0.106 | -0.0193 | No | ||
45 | SUPV3L1 | 1170072 | 4861 | 0.102 | -0.0221 | No | ||
46 | STK16 | 1740154 | 5044 | 0.093 | -0.0306 | No | ||
47 | FGF14 | 2630390 3520075 6770048 | 5366 | 0.079 | -0.0469 | No | ||
48 | RNF128 | 1230300 5670273 | 5449 | 0.077 | -0.0503 | No | ||
49 | DVL2 | 6110162 | 5617 | 0.070 | -0.0584 | No | ||
50 | TAC1 | 7000195 380706 | 5645 | 0.069 | -0.0589 | No | ||
51 | CTNS | 4480048 | 5670 | 0.068 | -0.0593 | No | ||
52 | HNRPH2 | 2630040 5720671 | 5769 | 0.065 | -0.0637 | No | ||
53 | SEC23IP | 4540484 6200047 | 5779 | 0.064 | -0.0633 | No | ||
54 | BDNF | 2940128 3520368 | 5794 | 0.064 | -0.0632 | No | ||
55 | SLC12A6 | 610278 1980035 5340671 | 5911 | 0.060 | -0.0686 | No | ||
56 | GLA | 4610364 | 6348 | 0.049 | -0.0916 | No | ||
57 | IRS4 | 430341 1190450 | 6513 | 0.045 | -0.0998 | No | ||
58 | GZMK | 1410148 | 6570 | 0.044 | -0.1023 | No | ||
59 | SLC1A7 | 1990181 | 6578 | 0.043 | -0.1021 | No | ||
60 | MAX | 5220021 | 6589 | 0.043 | -0.1020 | No | ||
61 | OMG | 6760066 | 6609 | 0.043 | -0.1024 | No | ||
62 | ELAVL3 | 2850014 | 6851 | 0.038 | -0.1150 | No | ||
63 | NCOA6 | 1780333 6450110 | 7120 | 0.033 | -0.1290 | No | ||
64 | PLS3 | 3290082 | 7121 | 0.033 | -0.1286 | No | ||
65 | VNN1 | 3940400 | 7565 | 0.025 | -0.1523 | No | ||
66 | CREB5 | 2320368 | 7776 | 0.021 | -0.1634 | No | ||
67 | C4A | 360286 3830100 5220750 6420132 | 7795 | 0.021 | -0.1640 | No | ||
68 | HNRPD | 4120021 | 7947 | 0.019 | -0.1720 | No | ||
69 | LAMA3 | 1190131 5290239 | 7956 | 0.019 | -0.1721 | No | ||
70 | UBE2B | 4780497 | 8000 | 0.018 | -0.1742 | No | ||
71 | CALR | 510446 | 8057 | 0.017 | -0.1770 | No | ||
72 | BTBD14B | 3520601 4280162 | 8213 | 0.015 | -0.1852 | No | ||
73 | RHOQ | 520161 | 8431 | 0.012 | -0.1968 | No | ||
74 | MAT2A | 4070026 4730079 6020280 | 8500 | 0.010 | -0.2004 | No | ||
75 | PIK3R1 | 4730671 | 8630 | 0.008 | -0.2073 | No | ||
76 | ILF3 | 940722 3190647 6520110 | 8663 | 0.008 | -0.2089 | No | ||
77 | BMP6 | 2100128 | 8904 | 0.005 | -0.2218 | No | ||
78 | EIF3S10 | 1190079 3840176 | 8954 | 0.004 | -0.2244 | No | ||
79 | CARKL | 6020068 | 9047 | 0.003 | -0.2294 | No | ||
80 | HOXD10 | 6100039 | 9137 | 0.002 | -0.2342 | No | ||
81 | HOXB5 | 2900538 | 9344 | -0.001 | -0.2454 | No | ||
82 | AP1S2 | 780279 4280707 | 9455 | -0.003 | -0.2513 | No | ||
83 | LRP5 | 2100397 3170484 | 9458 | -0.003 | -0.2513 | No | ||
84 | PFKFB1 | 2370128 | 9496 | -0.004 | -0.2533 | No | ||
85 | XPO1 | 540707 | 9544 | -0.004 | -0.2558 | No | ||
86 | FZD6 | 360288 | 9549 | -0.004 | -0.2560 | No | ||
87 | CAPN6 | 1740168 | 9594 | -0.005 | -0.2583 | No | ||
88 | LIN28 | 6590672 | 9613 | -0.005 | -0.2592 | No | ||
89 | DNMT3A | 4050068 4810717 | 9722 | -0.006 | -0.2650 | No | ||
90 | HOXC5 | 1580017 | 9850 | -0.008 | -0.2717 | No | ||
91 | UBXD2 | 4280092 | 9944 | -0.010 | -0.2766 | No | ||
92 | CBX5 | 3830072 6290167 | 10003 | -0.010 | -0.2796 | No | ||
93 | SLC17A2 | 870593 2810035 | 10014 | -0.011 | -0.2800 | No | ||
94 | PPARGC1A | 4670040 | 10233 | -0.014 | -0.2917 | No | ||
95 | MTHFD1 | 5900398 6520427 | 10432 | -0.017 | -0.3022 | No | ||
96 | TOM1L2 | 4810465 | 10496 | -0.018 | -0.3053 | No | ||
97 | CLCN5 | 4200390 | 10831 | -0.023 | -0.3231 | No | ||
98 | HOXA11 | 6980133 | 10835 | -0.023 | -0.3230 | No | ||
99 | FMR1 | 5050075 | 11131 | -0.028 | -0.3386 | No | ||
100 | PICALM | 1940280 | 11250 | -0.030 | -0.3446 | No | ||
101 | CPT1A | 6350093 | 11365 | -0.031 | -0.3503 | No | ||
102 | POGK | 5290315 | 11670 | -0.037 | -0.3663 | No | ||
103 | LHFP | 3440368 | 11702 | -0.038 | -0.3675 | No | ||
104 | PIP5K1A | 4560672 | 11935 | -0.042 | -0.3795 | No | ||
105 | UMPS | 2340541 4730438 | 12104 | -0.046 | -0.3879 | No | ||
106 | NPM1 | 4730427 | 12115 | -0.046 | -0.3878 | No | ||
107 | CRLF1 | 3520092 | 12216 | -0.049 | -0.3926 | No | ||
108 | SUMF1 | 730050 | 12365 | -0.053 | -0.3999 | No | ||
109 | FOXD3 | 6550156 | 12382 | -0.053 | -0.4000 | No | ||
110 | TYR | 5690139 | 12395 | -0.053 | -0.3999 | No | ||
111 | VLDLR | 870722 3060047 5340452 6550131 | 12484 | -0.055 | -0.4039 | No | ||
112 | APLN | 6620632 | 12565 | -0.057 | -0.4075 | No | ||
113 | ZIC3 | 380020 | 12924 | -0.068 | -0.4260 | No | ||
114 | ETV1 | 70735 2940603 5080463 | 13625 | -0.094 | -0.4626 | No | ||
115 | TGFB2 | 4920292 | 13877 | -0.105 | -0.4748 | No | ||
116 | NPTX1 | 3710736 | 13962 | -0.111 | -0.4778 | No | ||
117 | GGN | 1410528 4210082 5290170 | 14011 | -0.113 | -0.4788 | No | ||
118 | SMCR8 | 730653 | 14117 | -0.120 | -0.4829 | No | ||
119 | TOP3A | 7000435 | 14254 | -0.129 | -0.4884 | No | ||
120 | GNB2 | 2350053 | 14436 | -0.142 | -0.4963 | No | ||
121 | SLC23A2 | 6660722 | 14683 | -0.164 | -0.5074 | No | ||
122 | SSR1 | 5890100 | 14850 | -0.180 | -0.5139 | No | ||
123 | RUNX1 | 3840711 | 14869 | -0.183 | -0.5123 | No | ||
124 | LAMC2 | 450692 2680041 4200059 4670148 | 15015 | -0.199 | -0.5174 | No | ||
125 | KCNE4 | 2470102 | 15170 | -0.220 | -0.5227 | No | ||
126 | BLNK | 70288 6590092 | 15184 | -0.222 | -0.5203 | No | ||
127 | DNAJB5 | 2900215 | 15210 | -0.226 | -0.5185 | No | ||
128 | SYNPO2L | 5390719 | 15232 | -0.228 | -0.5165 | No | ||
129 | SIRT1 | 1190731 | 15314 | -0.239 | -0.5176 | No | ||
130 | CDKN2C | 5050750 5130148 | 15580 | -0.286 | -0.5280 | No | ||
131 | RAB3IL1 | 380685 5420176 | 15752 | -0.323 | -0.5328 | No | ||
132 | GABARAP | 1450286 | 15916 | -0.360 | -0.5366 | Yes | ||
133 | EPC1 | 1570050 5290095 6900193 | 15993 | -0.380 | -0.5355 | Yes | ||
134 | TNRC15 | 6760746 | 16000 | -0.382 | -0.5305 | Yes | ||
135 | SLC31A2 | 1450577 | 16008 | -0.384 | -0.5255 | Yes | ||
136 | UBE2L6 | 60048 1170687 | 16022 | -0.388 | -0.5208 | Yes | ||
137 | SQSTM1 | 6550056 | 16068 | -0.399 | -0.5177 | Yes | ||
138 | PPM1A | 1170301 5900273 | 16115 | -0.410 | -0.5145 | Yes | ||
139 | RAI14 | 770288 1660075 | 16156 | -0.421 | -0.5109 | Yes | ||
140 | TOPORS | 4060592 | 16243 | -0.443 | -0.5094 | Yes | ||
141 | TCERG1 | 2350551 4540397 5220746 | 16250 | -0.445 | -0.5035 | Yes | ||
142 | COMMD8 | 5890358 | 16277 | -0.455 | -0.4986 | Yes | ||
143 | CYR61 | 1240408 5290026 4120452 6550008 | 16340 | -0.480 | -0.4953 | Yes | ||
144 | TCF12 | 3610324 7000156 | 16359 | -0.484 | -0.4896 | Yes | ||
145 | AATF | 5220575 | 16436 | -0.505 | -0.4867 | Yes | ||
146 | ASNA1 | 3830041 | 16495 | -0.524 | -0.4825 | Yes | ||
147 | GPR65 | 3120551 | 16498 | -0.525 | -0.4754 | Yes | ||
148 | EIF4E | 1580403 70133 6380215 | 16676 | -0.587 | -0.4768 | Yes | ||
149 | BAX | 3830008 | 16778 | -0.628 | -0.4735 | Yes | ||
150 | UBXD3 | 5050193 | 16804 | -0.638 | -0.4660 | Yes | ||
151 | ATF7IP | 2690176 6770021 | 16813 | -0.642 | -0.4576 | Yes | ||
152 | CLN3 | 780368 | 16896 | -0.678 | -0.4526 | Yes | ||
153 | DCTN4 | 3390010 5550170 | 16989 | -0.716 | -0.4476 | Yes | ||
154 | RAB9A | 1690279 3710671 | 17259 | -0.845 | -0.4505 | Yes | ||
155 | ATP6V1C1 | 2690324 5220528 | 17305 | -0.865 | -0.4409 | Yes | ||
156 | H2AFY | 4730750 | 17353 | -0.896 | -0.4310 | Yes | ||
157 | MCAM | 5130270 6620577 | 17393 | -0.917 | -0.4204 | Yes | ||
158 | CD164 | 3830594 | 17441 | -0.949 | -0.4098 | Yes | ||
159 | TIMM8A | 110279 | 17443 | -0.952 | -0.3966 | Yes | ||
160 | NIT1 | 1230338 3940671 | 17552 | -0.999 | -0.3886 | Yes | ||
161 | PTMA | 5570148 | 17683 | -1.061 | -0.3809 | Yes | ||
162 | DDX3X | 2190020 | 17759 | -1.115 | -0.3695 | Yes | ||
163 | COMMD3 | 2510259 | 17788 | -1.142 | -0.3552 | Yes | ||
164 | PABPC1 | 2650180 2690253 6020632 1990270 | 17797 | -1.149 | -0.3397 | Yes | ||
165 | ALDH6A1 | 1770746 | 17943 | -1.249 | -0.3302 | Yes | ||
166 | AKAP12 | 1450739 | 18094 | -1.383 | -0.3191 | Yes | ||
167 | UBE4B | 780008 3610154 | 18163 | -1.473 | -0.3023 | Yes | ||
168 | MTCH2 | 3780603 6620215 | 18248 | -1.571 | -0.2851 | Yes | ||
169 | RHEBL1 | 2810576 | 18266 | -1.591 | -0.2639 | Yes | ||
170 | UTP14A | 6590048 | 18323 | -1.694 | -0.2434 | Yes | ||
171 | GPX1 | 4150093 | 18354 | -1.759 | -0.2206 | Yes | ||
172 | GRN | 4050239 | 18380 | -1.839 | -0.1964 | Yes | ||
173 | NUDC | 4780025 | 18392 | -1.882 | -0.1709 | Yes | ||
174 | SNX8 | 3450315 | 18445 | -2.000 | -0.1459 | Yes | ||
175 | EIF4B | 5390563 5270577 | 18473 | -2.090 | -0.1184 | Yes | ||
176 | KBTBD2 | 2320014 | 18488 | -2.165 | -0.0891 | Yes | ||
177 | DUSP1 | 6860121 | 18491 | -2.179 | -0.0589 | Yes | ||
178 | PFDN2 | 4230156 | 18537 | -2.348 | -0.0287 | Yes | ||
179 | PER1 | 3290315 | 18540 | -2.373 | 0.0041 | Yes |