Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #wtNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_wtNotch.cls#wtNotch_versus_absentNotch |
Upregulated in class | absentNotch |
GeneSet | V$USF_01 |
Enrichment Score (ES) | -0.5742401 |
Normalized Enrichment Score (NES) | -1.7287652 |
Nominal p-value | 0.0 |
FDR q-value | 0.09352711 |
FWER p-Value | 0.067 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | CHD4 | 5420059 6130338 6380717 | 406 | 1.424 | -0.0059 | No | ||
2 | HOXB4 | 540131 | 566 | 1.246 | -0.0004 | No | ||
3 | HMGN2 | 3140091 | 762 | 1.096 | 0.0015 | No | ||
4 | ZFYVE26 | 6860152 | 810 | 1.060 | 0.0109 | No | ||
5 | OPRS1 | 6130128 6290717 | 845 | 1.032 | 0.0208 | No | ||
6 | TEF | 1050050 3120397 4060487 | 879 | 1.008 | 0.0304 | No | ||
7 | PLCG2 | 5720008 | 1101 | 0.899 | 0.0286 | No | ||
8 | VPS16 | 430064 3390041 6860301 | 1113 | 0.893 | 0.0381 | No | ||
9 | HSPBAP1 | 4060022 | 1188 | 0.849 | 0.0437 | No | ||
10 | ZCCHC7 | 6510592 | 1300 | 0.793 | 0.0467 | No | ||
11 | CCAR1 | 3190092 | 1344 | 0.777 | 0.0532 | No | ||
12 | TFRC | 4050551 | 1727 | 0.618 | 0.0395 | No | ||
13 | ATF4 | 730441 1740195 | 1813 | 0.593 | 0.0416 | No | ||
14 | RANBP1 | 430215 1090180 | 2036 | 0.519 | 0.0354 | No | ||
15 | PRPS1 | 6350129 | 2061 | 0.513 | 0.0400 | No | ||
16 | VPS33A | 780113 | 2281 | 0.449 | 0.0332 | No | ||
17 | SMYD4 | 2640403 | 2392 | 0.415 | 0.0319 | No | ||
18 | GTF2H1 | 2570746 2650148 | 2403 | 0.412 | 0.0360 | No | ||
19 | TSC1 | 1850672 | 2415 | 0.410 | 0.0401 | No | ||
20 | ZNF318 | 5890091 6130021 | 2444 | 0.402 | 0.0431 | No | ||
21 | MRPL27 | 2060131 | 2609 | 0.363 | 0.0383 | No | ||
22 | BRDT | 3940102 | 2703 | 0.342 | 0.0372 | No | ||
23 | MYST3 | 5270500 | 2720 | 0.339 | 0.0402 | No | ||
24 | DHX35 | 1230440 | 2811 | 0.322 | 0.0389 | No | ||
25 | SGOL1 | 1980075 5220092 6020711 | 2993 | 0.288 | 0.0324 | No | ||
26 | GTF2A1 | 4120138 4920524 5390110 1230397 | 3090 | 0.274 | 0.0303 | No | ||
27 | ISGF3G | 3190131 7100142 | 3293 | 0.240 | 0.0221 | No | ||
28 | RGL1 | 1500097 6900450 | 3322 | 0.235 | 0.0232 | No | ||
29 | ATP6V1A | 6590242 | 3325 | 0.234 | 0.0257 | No | ||
30 | DIRC2 | 2810494 | 3362 | 0.230 | 0.0264 | No | ||
31 | SCYL1 | 5050717 | 3364 | 0.230 | 0.0290 | No | ||
32 | EEF1B2 | 4850400 6130161 | 3476 | 0.215 | 0.0254 | No | ||
33 | DUSP7 | 2940309 | 3538 | 0.207 | 0.0244 | No | ||
34 | ARMET | 5130670 | 3816 | 0.178 | 0.0114 | No | ||
35 | MORF4L2 | 6450133 | 3851 | 0.175 | 0.0116 | No | ||
36 | NFX1 | 450504 | 3877 | 0.172 | 0.0122 | No | ||
37 | GATA5 | 430465 | 3902 | 0.169 | 0.0128 | No | ||
38 | FEN1 | 1770541 | 4018 | 0.160 | 0.0084 | No | ||
39 | SLC26A2 | 2360278 | 4065 | 0.156 | 0.0076 | No | ||
40 | TESK2 | 6520524 | 4155 | 0.147 | 0.0045 | No | ||
41 | TAF6L | 1850056 | 4178 | 0.145 | 0.0049 | No | ||
42 | NEUROD1 | 3060619 | 4179 | 0.145 | 0.0066 | No | ||
43 | TOM1 | 940398 2190053 | 4236 | 0.141 | 0.0051 | No | ||
44 | POLR3C | 6940546 | 4305 | 0.136 | 0.0030 | No | ||
45 | HOXB7 | 4540706 4610358 | 4493 | 0.123 | -0.0058 | No | ||
46 | COPZ1 | 6940100 | 4494 | 0.123 | -0.0044 | No | ||
47 | ESR2 | 6220138 | 4532 | 0.121 | -0.0050 | No | ||
48 | JMJD2C | 3290341 | 4560 | 0.119 | -0.0051 | No | ||
49 | SLC36A1 | 5080242 | 4620 | 0.116 | -0.0070 | No | ||
50 | RBBP6 | 2320129 | 4707 | 0.111 | -0.0104 | No | ||
51 | HOXA9 | 610494 4730040 5130601 | 4718 | 0.111 | -0.0097 | No | ||
52 | NRIP3 | 1340372 | 4783 | 0.106 | -0.0120 | No | ||
53 | USP15 | 610592 3520504 | 5208 | 0.086 | -0.0340 | No | ||
54 | RAD9A | 110300 1940632 3990390 6040014 | 5268 | 0.084 | -0.0362 | No | ||
55 | DVL2 | 6110162 | 5617 | 0.070 | -0.0543 | No | ||
56 | BMP4 | 380113 | 5651 | 0.069 | -0.0553 | No | ||
57 | HNRPH2 | 2630040 5720671 | 5769 | 0.065 | -0.0609 | No | ||
58 | BDNF | 2940128 3520368 | 5794 | 0.064 | -0.0615 | No | ||
59 | RARG | 6760136 | 5805 | 0.064 | -0.0613 | No | ||
60 | PPP1R3C | 2640170 | 5849 | 0.062 | -0.0630 | No | ||
61 | SLC12A6 | 610278 1980035 5340671 | 5911 | 0.060 | -0.0656 | No | ||
62 | HOXA7 | 5910152 | 6346 | 0.049 | -0.0886 | No | ||
63 | GLA | 4610364 | 6348 | 0.049 | -0.0881 | No | ||
64 | PHC3 | 4920332 | 6367 | 0.048 | -0.0885 | No | ||
65 | IRS4 | 430341 1190450 | 6513 | 0.045 | -0.0958 | No | ||
66 | SLC1A7 | 1990181 | 6578 | 0.043 | -0.0988 | No | ||
67 | MAX | 5220021 | 6589 | 0.043 | -0.0989 | No | ||
68 | RNF146 | 1660735 | 6664 | 0.042 | -0.1024 | No | ||
69 | ELAVL3 | 2850014 | 6851 | 0.038 | -0.1121 | No | ||
70 | ARPC5 | 1740411 3450300 | 7402 | 0.027 | -0.1416 | No | ||
71 | BHLHB3 | 3450438 | 7842 | 0.020 | -0.1651 | No | ||
72 | HNRPD | 4120021 | 7947 | 0.019 | -0.1706 | No | ||
73 | UBE2B | 4780497 | 8000 | 0.018 | -0.1732 | No | ||
74 | KIAA1715 | 1190551 | 8014 | 0.018 | -0.1737 | No | ||
75 | EIF4G1 | 4070446 | 8585 | 0.009 | -0.2045 | No | ||
76 | ILF3 | 940722 3190647 6520110 | 8663 | 0.008 | -0.2086 | No | ||
77 | ODC1 | 5670168 | 8725 | 0.007 | -0.2118 | No | ||
78 | SEPT3 | 3830022 5290079 | 8771 | 0.006 | -0.2142 | No | ||
79 | EIF3S10 | 1190079 3840176 | 8954 | 0.004 | -0.2240 | No | ||
80 | HOXD10 | 6100039 | 9137 | 0.002 | -0.2339 | No | ||
81 | OPRD1 | 4280138 | 9221 | 0.001 | -0.2384 | No | ||
82 | HOXB5 | 2900538 | 9344 | -0.001 | -0.2450 | No | ||
83 | AP1S2 | 780279 4280707 | 9455 | -0.003 | -0.2509 | No | ||
84 | XPO1 | 540707 | 9544 | -0.004 | -0.2556 | No | ||
85 | AKAP10 | 2630504 5910577 | 9553 | -0.004 | -0.2560 | No | ||
86 | DNMT3A | 4050068 4810717 | 9722 | -0.006 | -0.2650 | No | ||
87 | HOXC5 | 1580017 | 9850 | -0.008 | -0.2718 | No | ||
88 | PCDHA10 | 3830725 | 9989 | -0.010 | -0.2792 | No | ||
89 | TRIM37 | 5270091 | 10314 | -0.015 | -0.2966 | No | ||
90 | ADAM10 | 3780156 | 10357 | -0.015 | -0.2987 | No | ||
91 | SNX5 | 1570021 6860609 | 10400 | -0.016 | -0.3008 | No | ||
92 | TOM1L2 | 4810465 | 10496 | -0.018 | -0.3057 | No | ||
93 | HOXA11 | 6980133 | 10835 | -0.023 | -0.3238 | No | ||
94 | UTY | 5890441 | 10985 | -0.025 | -0.3316 | No | ||
95 | NDUFS1 | 2650253 | 11020 | -0.026 | -0.3332 | No | ||
96 | FMR1 | 5050075 | 11131 | -0.028 | -0.3388 | No | ||
97 | AKAP1 | 110148 1740735 2260019 7000563 | 11225 | -0.029 | -0.3435 | No | ||
98 | PICALM | 1940280 | 11250 | -0.030 | -0.3445 | No | ||
99 | CPT1A | 6350093 | 11365 | -0.031 | -0.3503 | No | ||
100 | CGN | 5890139 6370167 6400537 | 11504 | -0.034 | -0.3574 | No | ||
101 | POGK | 5290315 | 11670 | -0.037 | -0.3659 | No | ||
102 | SET | 6650286 | 11986 | -0.043 | -0.3825 | No | ||
103 | SC5DL | 6650390 | 12051 | -0.045 | -0.3855 | No | ||
104 | NPM1 | 4730427 | 12115 | -0.046 | -0.3884 | No | ||
105 | SUMF1 | 730050 | 12365 | -0.053 | -0.4013 | No | ||
106 | FOXD3 | 6550156 | 12382 | -0.053 | -0.4016 | No | ||
107 | FSHR | 610041 7040121 | 12420 | -0.054 | -0.4030 | No | ||
108 | SYT3 | 6380017 | 12429 | -0.054 | -0.4028 | No | ||
109 | HOXA1 | 1190524 5420142 | 12476 | -0.055 | -0.4047 | No | ||
110 | ETV1 | 70735 2940603 5080463 | 13625 | -0.094 | -0.4659 | No | ||
111 | CUL5 | 450142 | 13798 | -0.101 | -0.4740 | No | ||
112 | NPTX1 | 3710736 | 13962 | -0.111 | -0.4816 | No | ||
113 | GGN | 1410528 4210082 5290170 | 14011 | -0.113 | -0.4829 | No | ||
114 | GNB2 | 2350053 | 14436 | -0.142 | -0.5043 | No | ||
115 | HTATIP | 5360739 | 14522 | -0.149 | -0.5072 | No | ||
116 | SSR1 | 5890100 | 14850 | -0.180 | -0.5229 | No | ||
117 | SIRT1 | 1190731 | 15314 | -0.239 | -0.5453 | No | ||
118 | RAB3IL1 | 380685 5420176 | 15752 | -0.323 | -0.5654 | No | ||
119 | GABARAP | 1450286 | 15916 | -0.360 | -0.5701 | Yes | ||
120 | EPC1 | 1570050 5290095 6900193 | 15993 | -0.380 | -0.5699 | Yes | ||
121 | TNRC15 | 6760746 | 16000 | -0.382 | -0.5659 | Yes | ||
122 | SLC31A2 | 1450577 | 16008 | -0.384 | -0.5620 | Yes | ||
123 | MCM2 | 5050139 | 16009 | -0.385 | -0.5576 | Yes | ||
124 | PPM1A | 1170301 5900273 | 16115 | -0.410 | -0.5586 | Yes | ||
125 | RAI14 | 770288 1660075 | 16156 | -0.421 | -0.5560 | Yes | ||
126 | TOPORS | 4060592 | 16243 | -0.443 | -0.5557 | Yes | ||
127 | COMMD8 | 5890358 | 16277 | -0.455 | -0.5523 | Yes | ||
128 | BRD2 | 1450300 5340484 6100605 | 16425 | -0.502 | -0.5546 | Yes | ||
129 | AATF | 5220575 | 16436 | -0.505 | -0.5494 | Yes | ||
130 | RBBP4 | 6650528 | 16496 | -0.524 | -0.5467 | Yes | ||
131 | RPA1 | 360452 | 16606 | -0.563 | -0.5462 | Yes | ||
132 | EIF4E | 1580403 70133 6380215 | 16676 | -0.587 | -0.5433 | Yes | ||
133 | BAX | 3830008 | 16778 | -0.628 | -0.5416 | Yes | ||
134 | UBXD3 | 5050193 | 16804 | -0.638 | -0.5358 | Yes | ||
135 | ATF7IP | 2690176 6770021 | 16813 | -0.642 | -0.5289 | Yes | ||
136 | RPL13A | 2680519 5700142 | 16819 | -0.644 | -0.5219 | Yes | ||
137 | MCOLN1 | 4480563 | 16835 | -0.649 | -0.5154 | Yes | ||
138 | CLN3 | 780368 | 16896 | -0.678 | -0.5109 | Yes | ||
139 | HPS3 | 6650348 | 16981 | -0.711 | -0.5074 | Yes | ||
140 | DCTN4 | 3390010 5550170 | 16989 | -0.716 | -0.4997 | Yes | ||
141 | IGF2R | 1570402 | 17052 | -0.749 | -0.4946 | Yes | ||
142 | RAB24 | 520601 4540739 | 17089 | -0.761 | -0.4879 | Yes | ||
143 | CD164 | 3830594 | 17441 | -0.949 | -0.4962 | Yes | ||
144 | TIMM8A | 110279 | 17443 | -0.952 | -0.4854 | Yes | ||
145 | UTX | 2900017 6770452 | 17446 | -0.954 | -0.4747 | Yes | ||
146 | CSRP2BP | 4570717 5550333 | 17534 | -0.996 | -0.4682 | Yes | ||
147 | GNAS | 630441 1850373 4050152 | 17542 | -0.997 | -0.4573 | Yes | ||
148 | NIT1 | 1230338 3940671 | 17552 | -0.999 | -0.4464 | Yes | ||
149 | ALG1 | 2570112 | 17557 | -0.999 | -0.4353 | Yes | ||
150 | GSK3B | 5360348 | 17561 | -1.000 | -0.4241 | Yes | ||
151 | SLC38A2 | 1470242 3800026 | 17587 | -1.006 | -0.4141 | Yes | ||
152 | PTMA | 5570148 | 17683 | -1.061 | -0.4072 | Yes | ||
153 | DDX3X | 2190020 | 17759 | -1.115 | -0.3987 | Yes | ||
154 | COMMD3 | 2510259 | 17788 | -1.142 | -0.3873 | Yes | ||
155 | HTF9C | 3190048 4120132 | 17852 | -1.188 | -0.3772 | Yes | ||
156 | GNA13 | 4590102 | 17876 | -1.205 | -0.3648 | Yes | ||
157 | ALDH6A1 | 1770746 | 17943 | -1.249 | -0.3542 | Yes | ||
158 | STMN1 | 1990717 | 18068 | -1.364 | -0.3455 | Yes | ||
159 | AKAP12 | 1450739 | 18094 | -1.383 | -0.3312 | Yes | ||
160 | OSGEP | 5700239 | 18158 | -1.465 | -0.3180 | Yes | ||
161 | UBE4B | 780008 3610154 | 18163 | -1.473 | -0.3015 | Yes | ||
162 | U2AF2 | 450600 4670128 5420292 | 18196 | -1.513 | -0.2861 | Yes | ||
163 | BOK | 1170373 5860446 | 18242 | -1.565 | -0.2708 | Yes | ||
164 | MTCH2 | 3780603 6620215 | 18248 | -1.571 | -0.2533 | Yes | ||
165 | APEX1 | 3190519 | 18290 | -1.637 | -0.2369 | Yes | ||
166 | ATIC | 4010593 6380463 | 18292 | -1.642 | -0.2184 | Yes | ||
167 | GPX1 | 4150093 | 18354 | -1.759 | -0.2018 | Yes | ||
168 | NUDC | 4780025 | 18392 | -1.882 | -0.1824 | Yes | ||
169 | LAMP1 | 2470524 | 18413 | -1.920 | -0.1618 | Yes | ||
170 | STX6 | 4850750 6770278 | 18434 | -1.963 | -0.1406 | Yes | ||
171 | EIF4B | 5390563 5270577 | 18473 | -2.090 | -0.1190 | Yes | ||
172 | HMOX1 | 1740687 | 18474 | -2.093 | -0.0952 | Yes | ||
173 | KBTBD2 | 2320014 | 18488 | -2.165 | -0.0714 | Yes | ||
174 | DUSP1 | 6860121 | 18491 | -2.179 | -0.0468 | Yes | ||
175 | PFDN2 | 4230156 | 18537 | -2.348 | -0.0227 | Yes | ||
176 | PER1 | 3290315 | 18540 | -2.373 | 0.0041 | Yes |