Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #wtNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_wtNotch.cls#wtNotch_versus_absentNotch |
Upregulated in class | wtNotch |
GeneSet | V$SP1_Q2_01 |
Enrichment Score (ES) | 0.42005536 |
Normalized Enrichment Score (NES) | 1.3049278 |
Nominal p-value | 0.012285012 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | BCL9L | 6940053 | 9 | 3.187 | 0.0426 | Yes | ||
2 | NOTCH3 | 3060603 | 51 | 2.482 | 0.0740 | Yes | ||
3 | PAK4 | 1690152 | 68 | 2.254 | 0.1036 | Yes | ||
4 | PIK4CB | 510450 1780452 | 116 | 2.061 | 0.1290 | Yes | ||
5 | TMEM24 | 5860039 | 147 | 1.952 | 0.1538 | Yes | ||
6 | EFEMP2 | 5550086 | 154 | 1.925 | 0.1795 | Yes | ||
7 | SEP15 | 1780451 2060450 5890451 | 240 | 1.724 | 0.1982 | Yes | ||
8 | SRR | 1190465 3800494 | 264 | 1.663 | 0.2194 | Yes | ||
9 | BCL3 | 3990440 | 301 | 1.592 | 0.2390 | Yes | ||
10 | CAMKK1 | 6370324 | 397 | 1.447 | 0.2534 | Yes | ||
11 | FBXL19 | 4570039 | 411 | 1.420 | 0.2720 | Yes | ||
12 | OAZ2 | 2810110 | 426 | 1.396 | 0.2901 | Yes | ||
13 | RHOG | 6760575 | 443 | 1.375 | 0.3078 | Yes | ||
14 | HSPB2 | 1990110 | 565 | 1.246 | 0.3181 | Yes | ||
15 | UPF2 | 4810471 | 655 | 1.173 | 0.3292 | Yes | ||
16 | VAMP2 | 2100100 | 690 | 1.144 | 0.3428 | Yes | ||
17 | DDX6 | 2630025 6770408 | 730 | 1.117 | 0.3558 | Yes | ||
18 | CRYAB | 4810619 | 861 | 1.021 | 0.3626 | Yes | ||
19 | TEF | 1050050 3120397 4060487 | 879 | 1.008 | 0.3753 | Yes | ||
20 | MXD4 | 4810113 | 910 | 0.999 | 0.3872 | Yes | ||
21 | SMARCD1 | 3060193 3850184 6400369 | 1299 | 0.794 | 0.3769 | Yes | ||
22 | BAD | 2120148 | 1513 | 0.707 | 0.3749 | Yes | ||
23 | RELA | 3830075 | 1529 | 0.699 | 0.3835 | Yes | ||
24 | GFRA1 | 3610152 | 1607 | 0.668 | 0.3884 | Yes | ||
25 | GAS7 | 2120358 6450494 | 1692 | 0.631 | 0.3924 | Yes | ||
26 | FBXO3 | 6760673 6860131 | 1863 | 0.575 | 0.3909 | Yes | ||
27 | SIPA1 | 5220687 | 1918 | 0.559 | 0.3956 | Yes | ||
28 | HAP1 | 1240010 4230079 6980195 | 1944 | 0.551 | 0.4017 | Yes | ||
29 | SESN2 | 2370019 | 1946 | 0.550 | 0.4090 | Yes | ||
30 | LYL1 | 2900242 | 2186 | 0.476 | 0.4025 | Yes | ||
31 | CGGBP1 | 4810053 | 2213 | 0.468 | 0.4074 | Yes | ||
32 | GGA1 | 70402 380168 | 2339 | 0.431 | 0.4065 | Yes | ||
33 | IRF2BP1 | 3170019 | 2358 | 0.426 | 0.4113 | Yes | ||
34 | CORO1C | 4570397 | 2604 | 0.364 | 0.4029 | Yes | ||
35 | PAX2 | 6040270 7000133 | 2610 | 0.363 | 0.4075 | Yes | ||
36 | CHKA | 510324 | 2718 | 0.340 | 0.4063 | Yes | ||
37 | MAP4K2 | 4200037 | 2766 | 0.331 | 0.4083 | Yes | ||
38 | NFAT5 | 2510411 5890195 6550152 | 2831 | 0.317 | 0.4091 | Yes | ||
39 | CDK5R1 | 3870161 | 2846 | 0.314 | 0.4126 | Yes | ||
40 | ASB7 | 520242 2450088 3990563 4280538 | 2854 | 0.313 | 0.4164 | Yes | ||
41 | RELB | 1400048 | 2866 | 0.311 | 0.4201 | Yes | ||
42 | SNX2 | 2470068 3360364 6510064 | 2944 | 0.298 | 0.4199 | No | ||
43 | ADCK1 | 6620707 | 3192 | 0.254 | 0.4099 | No | ||
44 | NTRK3 | 4050687 4070167 4610026 6100484 | 3216 | 0.251 | 0.4121 | No | ||
45 | PHLDA3 | 510398 | 3474 | 0.216 | 0.4011 | No | ||
46 | FBXO34 | 4010671 5700647 6450026 | 3483 | 0.215 | 0.4035 | No | ||
47 | ATP2A2 | 1090075 3990279 | 3485 | 0.214 | 0.4064 | No | ||
48 | WNT5A | 840685 3120152 | 3512 | 0.211 | 0.4078 | No | ||
49 | ACE | 1780161 4920315 | 3575 | 0.203 | 0.4072 | No | ||
50 | EIF2C1 | 6900551 | 3651 | 0.194 | 0.4058 | No | ||
51 | CACNA1D | 1740315 4730731 | 3656 | 0.194 | 0.4082 | No | ||
52 | SPAG9 | 580497 2510180 4210685 | 3897 | 0.170 | 0.3975 | No | ||
53 | ERG | 50154 1770739 | 3951 | 0.166 | 0.3968 | No | ||
54 | PPRC1 | 1740441 | 4000 | 0.161 | 0.3964 | No | ||
55 | EGLN2 | 540086 | 4060 | 0.156 | 0.3953 | No | ||
56 | EN1 | 5360168 7050025 | 4182 | 0.145 | 0.3907 | No | ||
57 | CBLN1 | 5670358 | 4224 | 0.142 | 0.3904 | No | ||
58 | HCFC1R1 | 6350500 | 4350 | 0.133 | 0.3854 | No | ||
59 | HOXB7 | 4540706 4610358 | 4493 | 0.123 | 0.3794 | No | ||
60 | RAB2B | 6200091 | 4604 | 0.116 | 0.3750 | No | ||
61 | MAP3K11 | 7000039 | 4629 | 0.115 | 0.3753 | No | ||
62 | TRIM28 | 380292 | 4682 | 0.113 | 0.3740 | No | ||
63 | TAL1 | 7040239 | 4931 | 0.098 | 0.3618 | No | ||
64 | SLITRK5 | 6590292 | 5002 | 0.095 | 0.3593 | No | ||
65 | WNT1 | 4780148 | 5003 | 0.095 | 0.3606 | No | ||
66 | CREB1 | 1500717 2230358 3610600 6550601 | 5196 | 0.087 | 0.3514 | No | ||
67 | ARHGEF19 | 940102 | 5272 | 0.084 | 0.3484 | No | ||
68 | DLX3 | 3190497 | 5279 | 0.084 | 0.3492 | No | ||
69 | HRH3 | 6180040 | 5302 | 0.082 | 0.3492 | No | ||
70 | CDH24 | 6980592 | 5332 | 0.081 | 0.3487 | No | ||
71 | SLC35F5 | 2360369 | 5371 | 0.079 | 0.3477 | No | ||
72 | ENAH | 1690292 5700300 | 5394 | 0.078 | 0.3476 | No | ||
73 | CDH2 | 520435 2450451 2760025 6650477 | 5439 | 0.077 | 0.3462 | No | ||
74 | EFNB3 | 5570594 | 5501 | 0.075 | 0.3439 | No | ||
75 | FGF12 | 1740446 2360037 | 5736 | 0.066 | 0.3321 | No | ||
76 | HCN4 | 1050026 | 5762 | 0.065 | 0.3316 | No | ||
77 | SIX4 | 6760022 | 5786 | 0.064 | 0.3313 | No | ||
78 | BDNF | 2940128 3520368 | 5794 | 0.064 | 0.3317 | No | ||
79 | TITF1 | 3390554 4540292 | 5862 | 0.062 | 0.3289 | No | ||
80 | ONECUT1 | 6450136 | 5888 | 0.061 | 0.3284 | No | ||
81 | RANBP10 | 2340184 | 5956 | 0.059 | 0.3256 | No | ||
82 | TBX2 | 1990563 | 6281 | 0.051 | 0.3087 | No | ||
83 | FGF11 | 840292 | 6345 | 0.049 | 0.3059 | No | ||
84 | TADA3L | 4210070 5720088 6660333 | 6410 | 0.047 | 0.3031 | No | ||
85 | FZD2 | 6480154 | 6464 | 0.046 | 0.3009 | No | ||
86 | NR2F2 | 3170609 3310577 | 6537 | 0.045 | 0.2976 | No | ||
87 | SLC18A3 | 3060035 | 6674 | 0.042 | 0.2907 | No | ||
88 | MDS1 | 6400072 | 6726 | 0.040 | 0.2885 | No | ||
89 | POLR2I | 4060400 | 6958 | 0.036 | 0.2765 | No | ||
90 | OSBP2 | 6510368 | 7080 | 0.034 | 0.2704 | No | ||
91 | NCOA6 | 1780333 6450110 | 7120 | 0.033 | 0.2687 | No | ||
92 | PHOX2A | 6650121 | 7144 | 0.032 | 0.2679 | No | ||
93 | GSC | 1580685 | 7180 | 0.031 | 0.2664 | No | ||
94 | TIMELESS | 3710315 | 7225 | 0.031 | 0.2645 | No | ||
95 | FSTL5 | 770280 | 7280 | 0.030 | 0.2619 | No | ||
96 | CLDN11 | 670338 | 7336 | 0.029 | 0.2593 | No | ||
97 | NTF5 | 6110239 | 7415 | 0.027 | 0.2555 | No | ||
98 | CHAT | 6840603 | 7667 | 0.023 | 0.2422 | No | ||
99 | BHLHB3 | 3450438 | 7842 | 0.020 | 0.2330 | No | ||
100 | PTPRJ | 4010707 | 7940 | 0.019 | 0.2280 | No | ||
101 | RAB26 | 5910025 | 8097 | 0.017 | 0.2198 | No | ||
102 | OSBPL9 | 2570373 | 8105 | 0.017 | 0.2196 | No | ||
103 | PTPN2 | 130315 | 8113 | 0.016 | 0.2195 | No | ||
104 | AKT2 | 3850541 3870519 | 8207 | 0.015 | 0.2146 | No | ||
105 | FEV | 840369 5860139 | 8444 | 0.011 | 0.2020 | No | ||
106 | PTHLH | 5290739 | 8456 | 0.011 | 0.2015 | No | ||
107 | CRY1 | 6770039 | 8643 | 0.008 | 0.1915 | No | ||
108 | NOL4 | 5050446 5360519 | 8868 | 0.005 | 0.1795 | No | ||
109 | CACNA1A | 6220164 | 9096 | 0.002 | 0.1672 | No | ||
110 | GRIN2A | 6550538 | 9212 | 0.001 | 0.1609 | No | ||
111 | DES | 1450341 | 9332 | -0.001 | 0.1545 | No | ||
112 | NXPH3 | 5860292 | 9464 | -0.003 | 0.1474 | No | ||
113 | DNMT3A | 4050068 4810717 | 9722 | -0.006 | 0.1336 | No | ||
114 | ADAM10 | 3780156 | 10357 | -0.015 | 0.0994 | No | ||
115 | KCNIP2 | 60088 1780324 | 10359 | -0.015 | 0.0996 | No | ||
116 | NUMBL | 6130360 6200333 | 10421 | -0.016 | 0.0965 | No | ||
117 | ADRB1 | 6860292 | 10526 | -0.018 | 0.0911 | No | ||
118 | ERBB3 | 5890372 | 10799 | -0.022 | 0.0766 | No | ||
119 | NLK | 2030010 2450041 | 10808 | -0.022 | 0.0765 | No | ||
120 | KCNMA1 | 1450402 | 11027 | -0.026 | 0.0650 | No | ||
121 | TIGD4 | 1780114 | 11220 | -0.029 | 0.0550 | No | ||
122 | ACCN2 | 6450465 | 11315 | -0.031 | 0.0503 | No | ||
123 | SOX2 | 630487 2230491 | 11468 | -0.033 | 0.0425 | No | ||
124 | JUB | 5860711 5900500 | 11905 | -0.042 | 0.0194 | No | ||
125 | KCNB1 | 3610035 | 11925 | -0.042 | 0.0190 | No | ||
126 | FGF5 | 5270204 | 12173 | -0.047 | 0.0062 | No | ||
127 | SP3 | 3840338 | 12229 | -0.049 | 0.0039 | No | ||
128 | PTCH2 | 2900092 | 12371 | -0.053 | -0.0030 | No | ||
129 | NXPH4 | 3830500 | 12405 | -0.053 | -0.0041 | No | ||
130 | PAK1 | 4540315 | 12714 | -0.061 | -0.0200 | No | ||
131 | APLP2 | 3610037 | 12715 | -0.061 | -0.0191 | No | ||
132 | TSNAXIP1 | 1770270 6180577 | 12726 | -0.062 | -0.0188 | No | ||
133 | KLF13 | 4670563 | 12746 | -0.062 | -0.0190 | No | ||
134 | CDH3 | 5390112 6860603 | 12860 | -0.066 | -0.0243 | No | ||
135 | LOXL4 | 6520095 | 12998 | -0.070 | -0.0308 | No | ||
136 | EDG8 | 1990441 | 13021 | -0.071 | -0.0310 | No | ||
137 | BCL6B | 60047 | 13147 | -0.075 | -0.0368 | No | ||
138 | GPR3 | 2970452 | 13411 | -0.085 | -0.0499 | No | ||
139 | DUSP15 | 1850044 6960196 | 13510 | -0.089 | -0.0540 | No | ||
140 | HSD11B2 | 5900053 | 13540 | -0.090 | -0.0543 | No | ||
141 | CAMK2G | 630097 | 13891 | -0.106 | -0.0719 | No | ||
142 | GGN | 1410528 4210082 5290170 | 14011 | -0.113 | -0.0768 | No | ||
143 | RNF24 | 4230280 6100070 6620739 | 14160 | -0.123 | -0.0832 | No | ||
144 | PIAS3 | 50204 240739 4060524 | 14271 | -0.131 | -0.0874 | No | ||
145 | ASCL2 | 1400273 | 14512 | -0.148 | -0.0984 | No | ||
146 | KLF16 | 4590725 | 14516 | -0.149 | -0.0965 | No | ||
147 | BCL7C | 460050 | 14622 | -0.159 | -0.1001 | No | ||
148 | SCARF2 | 5290184 | 15037 | -0.202 | -0.1198 | No | ||
149 | CLSTN1 | 6020019 | 15105 | -0.210 | -0.1206 | No | ||
150 | TBX3 | 2570672 | 15140 | -0.214 | -0.1195 | No | ||
151 | KCNN2 | 990025 3520524 | 15424 | -0.258 | -0.1314 | No | ||
152 | CLPTM1 | 670181 | 15684 | -0.307 | -0.1413 | No | ||
153 | FUT8 | 1340068 2340056 | 15738 | -0.320 | -0.1398 | No | ||
154 | SH3BP5 | 7100408 | 15747 | -0.322 | -0.1359 | No | ||
155 | GABARAP | 1450286 | 15916 | -0.360 | -0.1401 | No | ||
156 | HYAL2 | 1500152 | 15921 | -0.361 | -0.1355 | No | ||
157 | THRA | 6770341 110164 1990600 | 16183 | -0.427 | -0.1438 | No | ||
158 | ARPC4 | 2900056 | 16234 | -0.441 | -0.1406 | No | ||
159 | TCF12 | 3610324 7000156 | 16359 | -0.484 | -0.1408 | No | ||
160 | NFE2L1 | 6130053 | 16372 | -0.489 | -0.1348 | No | ||
161 | LDB1 | 5270601 | 16462 | -0.512 | -0.1327 | No | ||
162 | ARFIP1 | 3130601 | 16493 | -0.524 | -0.1273 | No | ||
163 | HS2ST1 | 3170088 | 16555 | -0.547 | -0.1232 | No | ||
164 | HIPK1 | 110193 | 16620 | -0.569 | -0.1189 | No | ||
165 | LASP1 | 1690528 2190341 6420341 | 16621 | -0.569 | -0.1112 | No | ||
166 | BMI1 | 3830026 2630204 | 16636 | -0.573 | -0.1042 | No | ||
167 | PIP5K2B | 6520156 6620541 | 16746 | -0.617 | -0.1018 | No | ||
168 | ANP32A | 510044 1580095 2680037 | 16791 | -0.634 | -0.0956 | No | ||
169 | TPM4 | 2100059 3850072 4920162 | 16814 | -0.642 | -0.0881 | No | ||
170 | BCL6 | 940100 | 16836 | -0.649 | -0.0805 | No | ||
171 | SNAG1 | 2760092 | 17328 | -0.879 | -0.0952 | No | ||
172 | GRB2 | 6650398 | 17463 | -0.960 | -0.0895 | No | ||
173 | FAF1 | 2450717 2510121 4730156 | 17569 | -1.001 | -0.0816 | No | ||
174 | ETV5 | 110017 | 17667 | -1.049 | -0.0727 | No | ||
175 | RAP1GDS1 | 50528 | 17714 | -1.086 | -0.0605 | No | ||
176 | ACLY | 1740609 | 17817 | -1.163 | -0.0503 | No | ||
177 | ZFP36 | 2030605 | 17941 | -1.248 | -0.0401 | No | ||
178 | BCL11B | 2680673 | 18154 | -1.464 | -0.0318 | No | ||
179 | KLF7 | 50390 | 18375 | -1.820 | -0.0191 | No | ||
180 | PER1 | 3290315 | 18540 | -2.373 | 0.0041 | No |