Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #wtNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_wtNotch.cls#wtNotch_versus_absentNotch |
Upregulated in class | absentNotch |
GeneSet | V$MYCMAX_03 |
Enrichment Score (ES) | -0.53445303 |
Normalized Enrichment Score (NES) | -1.6087282 |
Nominal p-value | 0.0 |
FDR q-value | 0.12981217 |
FWER p-Value | 0.402 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | LEF1 | 2470082 7100288 | 214 | 1.758 | 0.0091 | No | ||
2 | CHD4 | 5420059 6130338 6380717 | 406 | 1.424 | 0.0156 | No | ||
3 | PTGES2 | 4210097 | 408 | 1.422 | 0.0323 | No | ||
4 | FBXL19 | 4570039 | 411 | 1.420 | 0.0489 | No | ||
5 | HOXB4 | 540131 | 566 | 1.246 | 0.0553 | No | ||
6 | OPRS1 | 6130128 6290717 | 845 | 1.032 | 0.0524 | No | ||
7 | TEF | 1050050 3120397 4060487 | 879 | 1.008 | 0.0625 | No | ||
8 | UBXD1 | 5130079 5390167 | 975 | 0.971 | 0.0688 | No | ||
9 | PLCG2 | 5720008 | 1101 | 0.899 | 0.0726 | No | ||
10 | VPS16 | 430064 3390041 6860301 | 1113 | 0.893 | 0.0825 | No | ||
11 | ZCCHC7 | 6510592 | 1300 | 0.793 | 0.0818 | No | ||
12 | CCAR1 | 3190092 | 1344 | 0.777 | 0.0886 | No | ||
13 | KCNK5 | 4590504 6860687 | 1567 | 0.687 | 0.0847 | No | ||
14 | TGIF2 | 3840364 4050520 | 1638 | 0.655 | 0.0886 | No | ||
15 | ATF4 | 730441 1740195 | 1813 | 0.593 | 0.0862 | No | ||
16 | PRPS1 | 6350129 | 2061 | 0.513 | 0.0789 | No | ||
17 | NDUFA7 | 5900722 | 2220 | 0.467 | 0.0758 | No | ||
18 | VPS33A | 780113 | 2281 | 0.449 | 0.0778 | No | ||
19 | SMYD4 | 2640403 | 2392 | 0.415 | 0.0768 | No | ||
20 | ZNF318 | 5890091 6130021 | 2444 | 0.402 | 0.0788 | No | ||
21 | MRPL27 | 2060131 | 2609 | 0.363 | 0.0741 | No | ||
22 | MYST3 | 5270500 | 2720 | 0.339 | 0.0722 | No | ||
23 | KRTCAP2 | 5220040 | 2810 | 0.322 | 0.0712 | No | ||
24 | RELB | 1400048 | 2866 | 0.311 | 0.0718 | No | ||
25 | GTF2A1 | 4120138 4920524 5390110 1230397 | 3090 | 0.274 | 0.0630 | No | ||
26 | ISGF3G | 3190131 7100142 | 3293 | 0.240 | 0.0549 | No | ||
27 | RGL1 | 1500097 6900450 | 3322 | 0.235 | 0.0561 | No | ||
28 | SCYL1 | 5050717 | 3364 | 0.230 | 0.0566 | No | ||
29 | DUSP7 | 2940309 | 3538 | 0.207 | 0.0497 | No | ||
30 | HNRPA1 | 4670398 5050687 | 3753 | 0.184 | 0.0403 | No | ||
31 | CDC14A | 4050132 | 3803 | 0.180 | 0.0397 | No | ||
32 | ARMET | 5130670 | 3816 | 0.178 | 0.0412 | No | ||
33 | NFX1 | 450504 | 3877 | 0.172 | 0.0400 | No | ||
34 | GATA5 | 430465 | 3902 | 0.169 | 0.0406 | No | ||
35 | PPRC1 | 1740441 | 4000 | 0.161 | 0.0373 | No | ||
36 | TESK2 | 6520524 | 4155 | 0.147 | 0.0307 | No | ||
37 | TAF6L | 1850056 | 4178 | 0.145 | 0.0312 | No | ||
38 | NEUROD1 | 3060619 | 4179 | 0.145 | 0.0329 | No | ||
39 | TOM1 | 940398 2190053 | 4236 | 0.141 | 0.0315 | No | ||
40 | RPS28 | 3830221 | 4490 | 0.124 | 0.0193 | No | ||
41 | HOXB7 | 4540706 4610358 | 4493 | 0.123 | 0.0206 | No | ||
42 | COPZ1 | 6940100 | 4494 | 0.123 | 0.0221 | No | ||
43 | DLX2 | 2320438 4200673 | 4635 | 0.115 | 0.0158 | No | ||
44 | HOXA9 | 610494 4730040 5130601 | 4718 | 0.111 | 0.0127 | No | ||
45 | NRIP3 | 1340372 | 4783 | 0.106 | 0.0105 | No | ||
46 | SOCS5 | 3830398 7100093 | 4848 | 0.103 | 0.0082 | No | ||
47 | USP15 | 610592 3520504 | 5208 | 0.086 | -0.0102 | No | ||
48 | SNX16 | 870446 | 5571 | 0.072 | -0.0290 | No | ||
49 | TAC1 | 7000195 380706 | 5645 | 0.069 | -0.0321 | No | ||
50 | SEC23IP | 4540484 6200047 | 5779 | 0.064 | -0.0386 | No | ||
51 | SYT6 | 2510280 3850128 4540064 | 5957 | 0.059 | -0.0475 | No | ||
52 | HOXA7 | 5910152 | 6346 | 0.049 | -0.0680 | No | ||
53 | IRS4 | 430341 1190450 | 6513 | 0.045 | -0.0764 | No | ||
54 | NR0B2 | 2470692 | 6515 | 0.045 | -0.0759 | No | ||
55 | SLC1A7 | 1990181 | 6578 | 0.043 | -0.0788 | No | ||
56 | ZIC1 | 670113 | 6598 | 0.043 | -0.0793 | No | ||
57 | RNF146 | 1660735 | 6664 | 0.042 | -0.0823 | No | ||
58 | ELAVL3 | 2850014 | 6851 | 0.038 | -0.0920 | No | ||
59 | B3GALT2 | 430136 | 7204 | 0.031 | -0.1107 | No | ||
60 | ARPC5 | 1740411 3450300 | 7402 | 0.027 | -0.1211 | No | ||
61 | MEOX2 | 6400288 | 7561 | 0.025 | -0.1293 | No | ||
62 | HNRPD | 4120021 | 7947 | 0.019 | -0.1500 | No | ||
63 | UBE2B | 4780497 | 8000 | 0.018 | -0.1526 | No | ||
64 | MAT2A | 4070026 4730079 6020280 | 8500 | 0.010 | -0.1795 | No | ||
65 | CHST11 | 6760546 | 8508 | 0.010 | -0.1798 | No | ||
66 | EIF4G1 | 4070446 | 8585 | 0.009 | -0.1838 | No | ||
67 | ILF3 | 940722 3190647 6520110 | 8663 | 0.008 | -0.1879 | No | ||
68 | ODC1 | 5670168 | 8725 | 0.007 | -0.1911 | No | ||
69 | PLAGL1 | 3190082 6200193 | 8727 | 0.007 | -0.1911 | No | ||
70 | SEPT3 | 3830022 5290079 | 8771 | 0.006 | -0.1933 | No | ||
71 | BMP6 | 2100128 | 8904 | 0.005 | -0.2004 | No | ||
72 | EIF3S10 | 1190079 3840176 | 8954 | 0.004 | -0.2030 | No | ||
73 | SLCO1C1 | 5390494 | 9014 | 0.003 | -0.2062 | No | ||
74 | HOXD10 | 6100039 | 9137 | 0.002 | -0.2128 | No | ||
75 | OPRD1 | 4280138 | 9221 | 0.001 | -0.2173 | No | ||
76 | HOXB5 | 2900538 | 9344 | -0.001 | -0.2239 | No | ||
77 | AP1S2 | 780279 4280707 | 9455 | -0.003 | -0.2298 | No | ||
78 | CELSR3 | 5270731 7100082 | 9524 | -0.004 | -0.2335 | No | ||
79 | XPO1 | 540707 | 9544 | -0.004 | -0.2344 | No | ||
80 | SLC38A5 | 540093 | 9607 | -0.005 | -0.2377 | No | ||
81 | LIN28 | 6590672 | 9613 | -0.005 | -0.2380 | No | ||
82 | DNMT3A | 4050068 4810717 | 9722 | -0.006 | -0.2437 | No | ||
83 | HOXC5 | 1580017 | 9850 | -0.008 | -0.2505 | No | ||
84 | PCDHA10 | 3830725 | 9989 | -0.010 | -0.2579 | No | ||
85 | CBX5 | 3830072 6290167 | 10003 | -0.010 | -0.2585 | No | ||
86 | TRIM37 | 5270091 | 10314 | -0.015 | -0.2751 | No | ||
87 | SNX5 | 1570021 6860609 | 10400 | -0.016 | -0.2795 | No | ||
88 | PAX6 | 1190025 | 10695 | -0.021 | -0.2952 | No | ||
89 | HOXA11 | 6980133 | 10835 | -0.023 | -0.3025 | No | ||
90 | UTY | 5890441 | 10985 | -0.025 | -0.3103 | No | ||
91 | FMR1 | 5050075 | 11131 | -0.028 | -0.3178 | No | ||
92 | POU3F2 | 6620484 | 11185 | -0.028 | -0.3203 | No | ||
93 | TBC1D15 | 870673 | 11200 | -0.029 | -0.3208 | No | ||
94 | AKAP1 | 110148 1740735 2260019 7000563 | 11225 | -0.029 | -0.3217 | No | ||
95 | PICALM | 1940280 | 11250 | -0.030 | -0.3227 | No | ||
96 | CPT1A | 6350093 | 11365 | -0.031 | -0.3285 | No | ||
97 | GPC3 | 6180735 | 11867 | -0.041 | -0.3552 | No | ||
98 | NPM1 | 4730427 | 12115 | -0.046 | -0.3680 | No | ||
99 | TRIB1 | 2320435 | 12272 | -0.050 | -0.3759 | No | ||
100 | SYT3 | 6380017 | 12429 | -0.054 | -0.3837 | No | ||
101 | HOXA1 | 1190524 5420142 | 12476 | -0.055 | -0.3855 | No | ||
102 | DRD1 | 430025 | 12576 | -0.057 | -0.3902 | No | ||
103 | SNCAIP | 4010551 | 12820 | -0.064 | -0.4026 | No | ||
104 | ANKRD17 | 2120402 3850035 6400044 | 13226 | -0.077 | -0.4237 | No | ||
105 | CUGBP1 | 450292 510022 7050176 7050215 | 13610 | -0.093 | -0.4434 | No | ||
106 | CUL5 | 450142 | 13798 | -0.101 | -0.4523 | No | ||
107 | TGFB2 | 4920292 | 13877 | -0.105 | -0.4553 | No | ||
108 | NPTX1 | 3710736 | 13962 | -0.111 | -0.4585 | No | ||
109 | GGN | 1410528 4210082 5290170 | 14011 | -0.113 | -0.4598 | No | ||
110 | NEUROD2 | 5290097 | 14163 | -0.123 | -0.4665 | No | ||
111 | HTATIP | 5360739 | 14522 | -0.149 | -0.4842 | No | ||
112 | PABPC4 | 1990170 6760270 5390138 | 14772 | -0.171 | -0.4957 | No | ||
113 | SSR1 | 5890100 | 14850 | -0.180 | -0.4977 | No | ||
114 | SYNCRIP | 1690195 3140113 4670279 | 14861 | -0.182 | -0.4961 | No | ||
115 | SHMT1 | 5900132 | 15082 | -0.207 | -0.5056 | No | ||
116 | ADAM12 | 3390132 4070347 | 15196 | -0.224 | -0.5091 | No | ||
117 | SIRT1 | 1190731 | 15314 | -0.239 | -0.5126 | No | ||
118 | CDKN2C | 5050750 5130148 | 15580 | -0.286 | -0.5236 | No | ||
119 | LIG3 | 2940300 | 15590 | -0.288 | -0.5207 | No | ||
120 | RAB3IL1 | 380685 5420176 | 15752 | -0.323 | -0.5256 | No | ||
121 | GABARAP | 1450286 | 15916 | -0.360 | -0.5302 | Yes | ||
122 | EPC1 | 1570050 5290095 6900193 | 15993 | -0.380 | -0.5298 | Yes | ||
123 | TNRC15 | 6760746 | 16000 | -0.382 | -0.5257 | Yes | ||
124 | MCM2 | 5050139 | 16009 | -0.385 | -0.5216 | Yes | ||
125 | PPM1A | 1170301 5900273 | 16115 | -0.410 | -0.5224 | Yes | ||
126 | TOPORS | 4060592 | 16243 | -0.443 | -0.5241 | Yes | ||
127 | CBX8 | 50671 | 16379 | -0.490 | -0.5256 | Yes | ||
128 | BRD2 | 1450300 5340484 6100605 | 16425 | -0.502 | -0.5221 | Yes | ||
129 | CITED2 | 5670114 5130088 | 16426 | -0.502 | -0.5162 | Yes | ||
130 | RBBP4 | 6650528 | 16496 | -0.524 | -0.5138 | Yes | ||
131 | CTSF | 6100021 | 16526 | -0.536 | -0.5090 | Yes | ||
132 | RPA1 | 360452 | 16606 | -0.563 | -0.5067 | Yes | ||
133 | BMP7 | 870039 | 16661 | -0.581 | -0.5027 | Yes | ||
134 | EIF4E | 1580403 70133 6380215 | 16676 | -0.587 | -0.4966 | Yes | ||
135 | BAX | 3830008 | 16778 | -0.628 | -0.4946 | Yes | ||
136 | UBXD3 | 5050193 | 16804 | -0.638 | -0.4885 | Yes | ||
137 | RPL13A | 2680519 5700142 | 16819 | -0.644 | -0.4816 | Yes | ||
138 | DCTN4 | 3390010 5550170 | 16989 | -0.716 | -0.4823 | Yes | ||
139 | IGF2R | 1570402 | 17052 | -0.749 | -0.4769 | Yes | ||
140 | ATP6V1C1 | 2690324 5220528 | 17305 | -0.865 | -0.4803 | Yes | ||
141 | CD164 | 3830594 | 17441 | -0.949 | -0.4765 | Yes | ||
142 | TIMM8A | 110279 | 17443 | -0.952 | -0.4653 | Yes | ||
143 | UTX | 2900017 6770452 | 17446 | -0.954 | -0.4541 | Yes | ||
144 | CBARA1 | 360471 | 17489 | -0.973 | -0.4449 | Yes | ||
145 | ALDH3B1 | 4210010 6940403 | 17512 | -0.983 | -0.4345 | Yes | ||
146 | GNAS | 630441 1850373 4050152 | 17542 | -0.997 | -0.4243 | Yes | ||
147 | NIT1 | 1230338 3940671 | 17552 | -0.999 | -0.4131 | Yes | ||
148 | UCHL1 | 1230066 | 17556 | -0.999 | -0.4014 | Yes | ||
149 | SLC38A2 | 1470242 3800026 | 17587 | -1.006 | -0.3912 | Yes | ||
150 | GADD45G | 2510142 | 17680 | -1.058 | -0.3837 | Yes | ||
151 | PTMA | 5570148 | 17683 | -1.061 | -0.3713 | Yes | ||
152 | DDX3X | 2190020 | 17759 | -1.115 | -0.3622 | Yes | ||
153 | COMMD3 | 2510259 | 17788 | -1.142 | -0.3503 | Yes | ||
154 | PABPC1 | 2650180 2690253 6020632 1990270 | 17797 | -1.149 | -0.3372 | Yes | ||
155 | QTRTD1 | 7000053 | 17804 | -1.153 | -0.3239 | Yes | ||
156 | GJA1 | 5220731 | 17813 | -1.160 | -0.3106 | Yes | ||
157 | ALDH6A1 | 1770746 | 17943 | -1.249 | -0.3029 | Yes | ||
158 | STMN1 | 1990717 | 18068 | -1.364 | -0.2935 | Yes | ||
159 | UBE4B | 780008 3610154 | 18163 | -1.473 | -0.2813 | Yes | ||
160 | BOK | 1170373 5860446 | 18242 | -1.565 | -0.2670 | Yes | ||
161 | CEBPB | 2970019 | 18268 | -1.593 | -0.2496 | Yes | ||
162 | FKBP11 | 3170575 | 18313 | -1.677 | -0.2322 | Yes | ||
163 | UTP14A | 6590048 | 18323 | -1.694 | -0.2127 | Yes | ||
164 | H3F3A | 2900086 | 18400 | -1.891 | -0.1945 | Yes | ||
165 | LAMP1 | 2470524 | 18413 | -1.920 | -0.1725 | Yes | ||
166 | HEXA | 2630358 | 18420 | -1.931 | -0.1501 | Yes | ||
167 | EIF4B | 5390563 5270577 | 18473 | -2.090 | -0.1283 | Yes | ||
168 | HMOX1 | 1740687 | 18474 | -2.093 | -0.1036 | Yes | ||
169 | KBTBD2 | 2320014 | 18488 | -2.165 | -0.0787 | Yes | ||
170 | PFDN2 | 4230156 | 18537 | -2.348 | -0.0536 | Yes | ||
171 | PER1 | 3290315 | 18540 | -2.373 | -0.0258 | Yes | ||
172 | NR1D1 | 2360471 770746 6590204 | 18562 | -2.528 | 0.0029 | Yes |