Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #wtNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_wtNotch.cls#wtNotch_versus_absentNotch |
Upregulated in class | wtNotch |
GeneSet | V$HNF4_01 |
Enrichment Score (ES) | 0.39095727 |
Normalized Enrichment Score (NES) | 1.2294132 |
Nominal p-value | 0.041262135 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PAK4 | 1690152 | 68 | 2.254 | 0.0311 | Yes | ||
2 | TRAF4 | 3060041 4920528 6980286 | 213 | 1.762 | 0.0506 | Yes | ||
3 | USP52 | 3710215 6380133 | 392 | 1.453 | 0.0634 | Yes | ||
4 | GCH1 | 670364 6550358 | 410 | 1.422 | 0.0844 | Yes | ||
5 | TP53 | 6130707 | 432 | 1.390 | 0.1048 | Yes | ||
6 | SLC26A6 | 4810575 | 573 | 1.242 | 0.1164 | Yes | ||
7 | SESN3 | 110687 | 582 | 1.234 | 0.1350 | Yes | ||
8 | SLC25A25 | 1230605 | 648 | 1.178 | 0.1497 | Yes | ||
9 | ZSWIM3 | 1230563 | 684 | 1.148 | 0.1655 | Yes | ||
10 | RASGRP2 | 2970333 | 719 | 1.125 | 0.1811 | Yes | ||
11 | ETFDH | 4670358 | 773 | 1.086 | 0.1950 | Yes | ||
12 | PDZK1 | 2320128 | 778 | 1.082 | 0.2115 | Yes | ||
13 | BAZ2A | 730184 | 852 | 1.024 | 0.2234 | Yes | ||
14 | LPL | 1450735 2970706 | 856 | 1.023 | 0.2390 | Yes | ||
15 | PDE8A | 5080446 | 859 | 1.021 | 0.2547 | Yes | ||
16 | RTN4 | 50725 630647 870097 870184 | 886 | 1.005 | 0.2688 | Yes | ||
17 | LMAN2 | 430154 | 963 | 0.976 | 0.2798 | Yes | ||
18 | TPI1 | 1500215 2100154 | 1061 | 0.922 | 0.2888 | Yes | ||
19 | AP1B1 | 4290373 | 1189 | 0.849 | 0.2950 | Yes | ||
20 | NTNG2 | 1770438 6380408 | 1223 | 0.833 | 0.3061 | Yes | ||
21 | NIPSNAP1 | 6860138 | 1525 | 0.701 | 0.3006 | Yes | ||
22 | CLCN2 | 1940021 | 1670 | 0.640 | 0.3026 | Yes | ||
23 | TMPIT | 3830538 | 1730 | 0.618 | 0.3090 | Yes | ||
24 | GMPPB | 4610538 | 1737 | 0.615 | 0.3182 | Yes | ||
25 | PRKCSH | 3360398 | 1746 | 0.610 | 0.3272 | Yes | ||
26 | ADRB2 | 3290373 | 1756 | 0.609 | 0.3361 | Yes | ||
27 | PDE3B | 2030563 | 1905 | 0.562 | 0.3367 | Yes | ||
28 | AGPAT1 | 610056 | 1942 | 0.551 | 0.3433 | Yes | ||
29 | PKP4 | 3710400 5890097 | 2016 | 0.526 | 0.3475 | Yes | ||
30 | RPS3A | 2470086 | 2112 | 0.492 | 0.3499 | Yes | ||
31 | NR1H3 | 4810215 5570292 | 2116 | 0.491 | 0.3574 | Yes | ||
32 | PELO | 3440706 | 2133 | 0.488 | 0.3640 | Yes | ||
33 | MOV10 | 50673 430577 3870280 | 2174 | 0.478 | 0.3693 | Yes | ||
34 | COL15A1 | 6840113 | 2210 | 0.468 | 0.3746 | Yes | ||
35 | PDLIM7 | 4780136 | 2229 | 0.462 | 0.3808 | Yes | ||
36 | NET1 | 2900707 | 2242 | 0.460 | 0.3872 | Yes | ||
37 | SLC25A1 | 4050402 | 2300 | 0.442 | 0.3910 | Yes | ||
38 | TOMM70A | 780114 | 2471 | 0.394 | 0.3878 | No | ||
39 | FKBP5 | 2190048 | 2581 | 0.368 | 0.3876 | No | ||
40 | ASB7 | 520242 2450088 3990563 4280538 | 2854 | 0.313 | 0.3777 | No | ||
41 | MARK2 | 7210608 | 2995 | 0.288 | 0.3745 | No | ||
42 | CBX7 | 3940035 | 3035 | 0.282 | 0.3768 | No | ||
43 | PRG4 | 5860156 6650086 | 3050 | 0.280 | 0.3804 | No | ||
44 | PCBP4 | 6350722 | 3185 | 0.255 | 0.3770 | No | ||
45 | LTB4R2 | 1990746 | 3226 | 0.249 | 0.3787 | No | ||
46 | ZIC4 | 1500082 | 3386 | 0.226 | 0.3736 | No | ||
47 | EEF1B2 | 4850400 6130161 | 3476 | 0.215 | 0.3721 | No | ||
48 | SLC25A5 | 1980672 | 3495 | 0.213 | 0.3744 | No | ||
49 | GLTP | 3440603 | 3534 | 0.208 | 0.3755 | No | ||
50 | ARFGEF2 | 5550500 | 3572 | 0.203 | 0.3767 | No | ||
51 | PEX16 | 4560044 | 3728 | 0.186 | 0.3711 | No | ||
52 | OBSCN | 3610129 | 3848 | 0.175 | 0.3674 | No | ||
53 | JMJD1C | 940575 2120025 | 3954 | 0.165 | 0.3643 | No | ||
54 | HSPD1 | 60097 2030451 | 3998 | 0.161 | 0.3644 | No | ||
55 | LGALS4 | 2260215 3390338 | 4055 | 0.157 | 0.3638 | No | ||
56 | POU5F1 | 450739 4560605 | 4302 | 0.136 | 0.3526 | No | ||
57 | PRKAG1 | 6450091 | 4420 | 0.128 | 0.3482 | No | ||
58 | F2 | 5720280 | 4430 | 0.127 | 0.3497 | No | ||
59 | NEUROG2 | 5420278 | 4472 | 0.124 | 0.3494 | No | ||
60 | LRRN1 | 3290154 | 4589 | 0.117 | 0.3449 | No | ||
61 | MAP3K11 | 7000039 | 4629 | 0.115 | 0.3446 | No | ||
62 | PCK1 | 7000358 | 4677 | 0.113 | 0.3438 | No | ||
63 | HOXA9 | 610494 4730040 5130601 | 4718 | 0.111 | 0.3433 | No | ||
64 | PTPRG | 2650524 1340022 | 4784 | 0.106 | 0.3414 | No | ||
65 | PAFAH2 | 3140451 5720593 6510014 | 4820 | 0.104 | 0.3411 | No | ||
66 | CHRDL1 | 1580037 6380204 | 4833 | 0.104 | 0.3421 | No | ||
67 | CREB1 | 1500717 2230358 3610600 6550601 | 5196 | 0.087 | 0.3238 | No | ||
68 | CNTFR | 4480092 6200064 | 5242 | 0.085 | 0.3226 | No | ||
69 | KCNE1L | 4670092 | 5324 | 0.081 | 0.3195 | No | ||
70 | UBE2R2 | 1230504 | 5325 | 0.081 | 0.3208 | No | ||
71 | SEC24C | 6980707 | 5398 | 0.078 | 0.3181 | No | ||
72 | PPP1R14D | 2190168 | 5757 | 0.065 | 0.2997 | No | ||
73 | PAX7 | 6860593 | 5924 | 0.060 | 0.2916 | No | ||
74 | SYT6 | 2510280 3850128 4540064 | 5957 | 0.059 | 0.2908 | No | ||
75 | PITX2 | 870537 2690139 | 6007 | 0.058 | 0.2890 | No | ||
76 | FLNC | 2360048 5050270 | 6135 | 0.055 | 0.2829 | No | ||
77 | TRPC5 | 3390270 | 6202 | 0.053 | 0.2802 | No | ||
78 | GPR124 | 510292 6290047 | 6230 | 0.052 | 0.2795 | No | ||
79 | RARB | 430139 1410138 | 6383 | 0.048 | 0.2720 | No | ||
80 | FABP2 | 5050673 | 6506 | 0.045 | 0.2661 | No | ||
81 | HOXA10 | 6110397 7100458 | 6508 | 0.045 | 0.2667 | No | ||
82 | TCF2 | 870338 5050632 | 6522 | 0.045 | 0.2667 | No | ||
83 | NRAP | 1780433 | 6650 | 0.042 | 0.2605 | No | ||
84 | SLC26A3 | 380750 | 6936 | 0.037 | 0.2456 | No | ||
85 | SP8 | 4060576 | 7014 | 0.035 | 0.2419 | No | ||
86 | TIMELESS | 3710315 | 7225 | 0.031 | 0.2310 | No | ||
87 | SS18 | 1940440 2900072 6900129 | 7307 | 0.029 | 0.2271 | No | ||
88 | DNAJA2 | 2630253 6860358 | 7523 | 0.026 | 0.2158 | No | ||
89 | C4A | 360286 3830100 5220750 6420132 | 7795 | 0.021 | 0.2014 | No | ||
90 | CRABP2 | 6940725 | 8148 | 0.016 | 0.1826 | No | ||
91 | AKT2 | 3850541 3870519 | 8207 | 0.015 | 0.1797 | No | ||
92 | KYNU | 1410435 | 8369 | 0.012 | 0.1711 | No | ||
93 | LRRC19 | 2680025 | 8428 | 0.012 | 0.1681 | No | ||
94 | EIF4G1 | 4070446 | 8585 | 0.009 | 0.1598 | No | ||
95 | GIPC2 | 3800463 | 8884 | 0.005 | 0.1437 | No | ||
96 | GOLGA4 | 460300 | 9082 | 0.002 | 0.1331 | No | ||
97 | MLLT6 | 3870168 | 9126 | 0.002 | 0.1308 | No | ||
98 | GBE1 | 2190368 | 9129 | 0.002 | 0.1307 | No | ||
99 | HOXD10 | 6100039 | 9137 | 0.002 | 0.1303 | No | ||
100 | FGF10 | 730458 840706 | 9201 | 0.001 | 0.1269 | No | ||
101 | WNT3 | 2360685 | 9398 | -0.002 | 0.1163 | No | ||
102 | INHBC | 3780242 | 9478 | -0.003 | 0.1121 | No | ||
103 | PFKFB1 | 2370128 | 9496 | -0.004 | 0.1112 | No | ||
104 | PPARA | 2060026 | 9595 | -0.005 | 0.1060 | No | ||
105 | SLC7A9 | 5420735 5700450 | 9626 | -0.005 | 0.1044 | No | ||
106 | TLK2 | 1170161 | 9725 | -0.007 | 0.0992 | No | ||
107 | CALB1 | 460070 | 9736 | -0.007 | 0.0988 | No | ||
108 | MYH10 | 2640673 | 9871 | -0.008 | 0.0916 | No | ||
109 | NGEF | 3190538 | 9877 | -0.009 | 0.0915 | No | ||
110 | SNCB | 3360133 | 9986 | -0.010 | 0.0858 | No | ||
111 | F13B | 6220278 | 10042 | -0.011 | 0.0830 | No | ||
112 | RAB33A | 6590195 | 10053 | -0.011 | 0.0826 | No | ||
113 | PPARGC1A | 4670040 | 10233 | -0.014 | 0.0731 | No | ||
114 | PRDM16 | 4120541 | 10262 | -0.014 | 0.0718 | No | ||
115 | EDN3 | 2690722 | 10447 | -0.017 | 0.0621 | No | ||
116 | MUCDHL | 5720056 | 10465 | -0.017 | 0.0614 | No | ||
117 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 10522 | -0.018 | 0.0587 | No | ||
118 | SLC7A7 | 510601 2810152 | 10724 | -0.021 | 0.0481 | No | ||
119 | ERBB3 | 5890372 | 10799 | -0.022 | 0.0444 | No | ||
120 | HR | 2690095 6200300 | 10905 | -0.024 | 0.0391 | No | ||
121 | NDUFS1 | 2650253 | 11020 | -0.026 | 0.0333 | No | ||
122 | PRDM1 | 3170347 3520301 | 11059 | -0.026 | 0.0316 | No | ||
123 | NKX2-2 | 4150731 | 11094 | -0.027 | 0.0302 | No | ||
124 | CDH6 | 4730541 | 11137 | -0.028 | 0.0284 | No | ||
125 | SLC34A1 | 430044 | 11234 | -0.029 | 0.0236 | No | ||
126 | ADAMTS19 | 2680739 | 11280 | -0.030 | 0.0216 | No | ||
127 | NR2C2 | 6100097 | 11455 | -0.033 | 0.0127 | No | ||
128 | CREB3L2 | 3390484 | 11552 | -0.035 | 0.0080 | No | ||
129 | HOXD3 | 6450154 | 11581 | -0.035 | 0.0071 | No | ||
130 | PGF | 4810593 | 11737 | -0.038 | -0.0008 | No | ||
131 | SERPINF1 | 7040367 | 11826 | -0.040 | -0.0049 | No | ||
132 | SLC22A18 | 7050168 | 12107 | -0.046 | -0.0194 | No | ||
133 | PKLR | 1170400 2470114 | 12255 | -0.050 | -0.0266 | No | ||
134 | PTBP2 | 1240398 | 12513 | -0.056 | -0.0397 | No | ||
135 | CDX2 | 3850349 | 12828 | -0.065 | -0.0557 | No | ||
136 | SPRY4 | 1570594 | 12895 | -0.067 | -0.0583 | No | ||
137 | PRRX2 | 4260603 | 13059 | -0.072 | -0.0660 | No | ||
138 | KLHL1 | 6350021 | 13242 | -0.078 | -0.0747 | No | ||
139 | DUSP3 | 1240129 6840215 | 13300 | -0.080 | -0.0765 | No | ||
140 | PRKCD | 770592 | 13430 | -0.086 | -0.0822 | No | ||
141 | SOX5 | 2370576 2900167 3190128 5050528 | 13552 | -0.091 | -0.0874 | No | ||
142 | F10 | 3830450 | 13593 | -0.092 | -0.0881 | No | ||
143 | TCF1 | 5390022 | 13745 | -0.099 | -0.0948 | No | ||
144 | SEMA3B | 5570563 | 13754 | -0.099 | -0.0937 | No | ||
145 | TBX5 | 2900132 6370484 | 13980 | -0.112 | -0.1042 | No | ||
146 | EPHA3 | 2190497 5080059 | 14035 | -0.116 | -0.1053 | No | ||
147 | RBP2 | 2060097 | 14296 | -0.133 | -0.1174 | No | ||
148 | LMX1B | 1260561 | 14423 | -0.141 | -0.1220 | No | ||
149 | RNF5 | 2760088 | 14574 | -0.154 | -0.1278 | No | ||
150 | ARCN1 | 5820273 | 14605 | -0.157 | -0.1270 | No | ||
151 | PAPLN | 2510592 | 14657 | -0.162 | -0.1272 | No | ||
152 | UBE4A | 6100520 | 14754 | -0.169 | -0.1298 | No | ||
153 | SLC23A3 | 6840152 | 14872 | -0.183 | -0.1333 | No | ||
154 | PIP5K2A | 5220497 | 14934 | -0.191 | -0.1337 | No | ||
155 | SCT | 2230348 | 14935 | -0.191 | -0.1307 | No | ||
156 | SLC25A4 | 2360519 | 15006 | -0.198 | -0.1315 | No | ||
157 | DAB2IP | 3170064 6200441 | 15123 | -0.212 | -0.1345 | No | ||
158 | SNAP25 | 360520 | 15235 | -0.228 | -0.1370 | No | ||
159 | CACNB2 | 1500095 7330707 | 15276 | -0.234 | -0.1355 | No | ||
160 | INSR | 1190504 | 15366 | -0.247 | -0.1366 | No | ||
161 | AKAP11 | 5050685 | 15447 | -0.261 | -0.1369 | No | ||
162 | NEK6 | 3360687 | 15498 | -0.272 | -0.1354 | No | ||
163 | PPARG | 1990168 2680603 6130632 | 15518 | -0.276 | -0.1321 | No | ||
164 | PABPN1 | 460519 | 15572 | -0.285 | -0.1306 | No | ||
165 | SELM | 450458 | 15760 | -0.325 | -0.1357 | No | ||
166 | APOM | 2340010 | 16011 | -0.385 | -0.1433 | No | ||
167 | OVOL1 | 1690131 | 16101 | -0.406 | -0.1419 | No | ||
168 | GATA4 | 1410215 2690609 | 16110 | -0.409 | -0.1360 | No | ||
169 | G6PC | 430093 | 16141 | -0.416 | -0.1312 | No | ||
170 | SMYD5 | 6220025 | 16216 | -0.435 | -0.1285 | No | ||
171 | PCTK1 | 4560079 | 16444 | -0.506 | -0.1330 | No | ||
172 | LRP1 | 6270386 | 16492 | -0.524 | -0.1274 | No | ||
173 | POLR2H | 5890242 | 16552 | -0.546 | -0.1222 | No | ||
174 | SFRS6 | 60224 | 16682 | -0.590 | -0.1201 | No | ||
175 | RNF103 | 840452 | 16750 | -0.618 | -0.1142 | No | ||
176 | LRFN4 | 5670368 | 17059 | -0.751 | -0.1193 | No | ||
177 | SMOC1 | 840039 | 17120 | -0.777 | -0.1105 | No | ||
178 | IGF1R | 3360494 | 17142 | -0.786 | -0.0995 | No | ||
179 | MRPS28 | 2230373 | 17248 | -0.840 | -0.0922 | No | ||
180 | GPD1 | 2480095 | 17342 | -0.886 | -0.0836 | No | ||
181 | RHOB | 1500309 | 17468 | -0.964 | -0.0755 | No | ||
182 | RBMS1 | 6400014 | 17654 | -1.040 | -0.0694 | No | ||
183 | MAGMAS | 580064 4920452 | 17767 | -1.118 | -0.0582 | No | ||
184 | SATB1 | 5670154 | 18090 | -1.381 | -0.0544 | No | ||
185 | BCL11B | 2680673 | 18154 | -1.464 | -0.0352 | No | ||
186 | HSPE1 | 3170438 | 18307 | -1.669 | -0.0176 | No | ||
187 | SEPP1 | 450273 | 18506 | -2.219 | 0.0060 | No |