Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #wtNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_wtNotch.cls#wtNotch_versus_absentNotch |
Upregulated in class | wtNotch |
GeneSet | V$ETS2_B |
Enrichment Score (ES) | 0.39671972 |
Normalized Enrichment Score (NES) | 1.2384527 |
Nominal p-value | 0.041564792 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | POU2AF1 | 5690242 | 1 | 4.937 | 0.0549 | Yes | ||
2 | GNB1L | 3840368 5270215 | 33 | 2.662 | 0.0829 | Yes | ||
3 | RASAL1 | 3710112 | 57 | 2.379 | 0.1081 | Yes | ||
4 | GIT2 | 6040039 6770181 | 107 | 2.094 | 0.1288 | Yes | ||
5 | MAPKAPK2 | 2850500 | 221 | 1.746 | 0.1421 | Yes | ||
6 | GCNT2 | 6400162 2370609 2760309 4540465 6100280 | 228 | 1.733 | 0.1610 | Yes | ||
7 | FGR | 3780047 | 265 | 1.662 | 0.1776 | Yes | ||
8 | BCL3 | 3990440 | 301 | 1.592 | 0.1934 | Yes | ||
9 | LCP1 | 4280397 | 310 | 1.578 | 0.2105 | Yes | ||
10 | AAMP | 2640059 | 329 | 1.551 | 0.2268 | Yes | ||
11 | CREB3 | 5220408 | 428 | 1.396 | 0.2370 | Yes | ||
12 | RNF40 | 3610397 | 508 | 1.306 | 0.2473 | Yes | ||
13 | PPP1R9B | 3130619 | 585 | 1.227 | 0.2568 | Yes | ||
14 | BAZ2A | 730184 | 852 | 1.024 | 0.2538 | Yes | ||
15 | DMTF1 | 5910047 1570497 2480100 6620239 | 916 | 0.998 | 0.2615 | Yes | ||
16 | PSEN1 | 130403 2030647 6100603 | 922 | 0.996 | 0.2723 | Yes | ||
17 | ARHGEF6 | 4780164 6380450 | 950 | 0.984 | 0.2818 | Yes | ||
18 | TNNI2 | 5910739 | 980 | 0.963 | 0.2909 | Yes | ||
19 | L3MBTL2 | 6020341 | 1082 | 0.910 | 0.2956 | Yes | ||
20 | CLTA | 450010 | 1247 | 0.819 | 0.2958 | Yes | ||
21 | NEDD8 | 2350722 | 1448 | 0.733 | 0.2931 | Yes | ||
22 | RAB11A | 5360079 | 1570 | 0.686 | 0.2942 | Yes | ||
23 | ZHX2 | 2900452 | 1580 | 0.680 | 0.3013 | Yes | ||
24 | CAMK1D | 1660100 2350309 | 1609 | 0.667 | 0.3072 | Yes | ||
25 | MCTS1 | 6130133 | 1614 | 0.666 | 0.3144 | Yes | ||
26 | TGIF2 | 3840364 4050520 | 1638 | 0.655 | 0.3204 | Yes | ||
27 | GTF2B | 6860685 | 1770 | 0.604 | 0.3200 | Yes | ||
28 | RGS3 | 60670 540736 1340180 1500369 3390735 4010131 4610402 6380114 | 1782 | 0.602 | 0.3261 | Yes | ||
29 | IL7R | 2060088 6380500 | 1849 | 0.579 | 0.3290 | Yes | ||
30 | GALE | 3610400 6290072 | 1855 | 0.577 | 0.3352 | Yes | ||
31 | SLC9A3R1 | 6020373 | 1881 | 0.568 | 0.3401 | Yes | ||
32 | CUEDC1 | 1660463 | 1893 | 0.566 | 0.3458 | Yes | ||
33 | SIPA1 | 5220687 | 1918 | 0.559 | 0.3508 | Yes | ||
34 | EGR1 | 4610347 | 1925 | 0.558 | 0.3566 | Yes | ||
35 | LAT | 3170025 | 1959 | 0.545 | 0.3609 | Yes | ||
36 | CDKN1B | 3800025 6450044 | 1990 | 0.533 | 0.3652 | Yes | ||
37 | IKBKB | 6840072 | 1993 | 0.532 | 0.3710 | Yes | ||
38 | ITGB7 | 4670619 | 2006 | 0.529 | 0.3763 | Yes | ||
39 | ATP8B2 | 6590403 | 2019 | 0.525 | 0.3815 | Yes | ||
40 | TLN1 | 6590411 | 2043 | 0.517 | 0.3860 | Yes | ||
41 | BZW2 | 940079 | 2106 | 0.495 | 0.3881 | Yes | ||
42 | CA4 | 130100 | 2141 | 0.486 | 0.3917 | Yes | ||
43 | LYL1 | 2900242 | 2186 | 0.476 | 0.3946 | Yes | ||
44 | SLC31A1 | 4590161 6940154 | 2294 | 0.444 | 0.3937 | Yes | ||
45 | ESM1 | 1410594 | 2329 | 0.434 | 0.3967 | Yes | ||
46 | CORO1C | 4570397 | 2604 | 0.364 | 0.3859 | No | ||
47 | TMOD3 | 840088 | 2639 | 0.357 | 0.3880 | No | ||
48 | SSBP4 | 2570735 | 2707 | 0.342 | 0.3882 | No | ||
49 | CTSW | 360368 | 2733 | 0.337 | 0.3906 | No | ||
50 | EIF5A | 1500059 5290022 6370026 | 2822 | 0.319 | 0.3894 | No | ||
51 | ORC4L | 4230538 5550288 | 2855 | 0.313 | 0.3911 | No | ||
52 | IRAK4 | 5390156 6130594 | 2920 | 0.302 | 0.3910 | No | ||
53 | ARHGDIB | 4730433 | 2922 | 0.301 | 0.3943 | No | ||
54 | MAP4K1 | 4060692 | 3032 | 0.284 | 0.3916 | No | ||
55 | C1QTNF6 | 2030592 | 3126 | 0.267 | 0.3895 | No | ||
56 | DPP3 | 2680725 3780670 | 3184 | 0.255 | 0.3892 | No | ||
57 | DGKZ | 3460041 6400129 | 3342 | 0.233 | 0.3833 | No | ||
58 | CDH5 | 5340487 | 3396 | 0.225 | 0.3829 | No | ||
59 | TAF5 | 3450288 5890193 6860435 | 3640 | 0.195 | 0.3719 | No | ||
60 | CACNA1D | 1740315 4730731 | 3656 | 0.194 | 0.3733 | No | ||
61 | EPHA2 | 5890056 | 3828 | 0.177 | 0.3660 | No | ||
62 | SPI1 | 1410397 | 3866 | 0.173 | 0.3659 | No | ||
63 | PSIP1 | 1780082 3190435 5050594 | 3876 | 0.172 | 0.3673 | No | ||
64 | SEMA4C | 1980315 | 3948 | 0.166 | 0.3653 | No | ||
65 | PPRC1 | 1740441 | 4000 | 0.161 | 0.3643 | No | ||
66 | LGALS4 | 2260215 3390338 | 4055 | 0.157 | 0.3631 | No | ||
67 | MYCT1 | 5670044 | 4099 | 0.152 | 0.3625 | No | ||
68 | RAB20 | 2640601 | 4103 | 0.152 | 0.3640 | No | ||
69 | NT5C3 | 1570075 | 4154 | 0.147 | 0.3630 | No | ||
70 | FGFR4 | 2650072 | 4280 | 0.138 | 0.3577 | No | ||
71 | GMPR2 | 4920204 | 4627 | 0.115 | 0.3402 | No | ||
72 | MAP3K11 | 7000039 | 4629 | 0.115 | 0.3415 | No | ||
73 | HAPLN1 | 580398 | 4892 | 0.100 | 0.3284 | No | ||
74 | LIFR | 3360068 3830102 | 5009 | 0.095 | 0.3231 | No | ||
75 | ACTR2 | 1170332 | 5322 | 0.082 | 0.3071 | No | ||
76 | OLFM1 | 3360161 5570066 | 5415 | 0.078 | 0.3030 | No | ||
77 | RNF128 | 1230300 5670273 | 5449 | 0.077 | 0.3020 | No | ||
78 | EFNB3 | 5570594 | 5501 | 0.075 | 0.3001 | No | ||
79 | HOXC4 | 1940193 | 5550 | 0.073 | 0.2983 | No | ||
80 | CAST | 3850082 5420671 6200156 | 5749 | 0.065 | 0.2883 | No | ||
81 | APOB48R | 2810070 | 5841 | 0.063 | 0.2840 | No | ||
82 | VASP | 7050500 | 5945 | 0.059 | 0.2791 | No | ||
83 | LYN | 6040600 | 6066 | 0.056 | 0.2732 | No | ||
84 | RNF12 | 6860717 | 6104 | 0.055 | 0.2718 | No | ||
85 | FLNC | 2360048 5050270 | 6135 | 0.055 | 0.2708 | No | ||
86 | HOXA10 | 6110397 7100458 | 6508 | 0.045 | 0.2511 | No | ||
87 | ANGPTL1 | 4570528 5290301 6400541 | 6524 | 0.045 | 0.2508 | No | ||
88 | RTKN | 5910253 6380082 | 6552 | 0.044 | 0.2498 | No | ||
89 | TREX2 | 4920707 | 6568 | 0.044 | 0.2495 | No | ||
90 | IL12B | 460008 | 6572 | 0.044 | 0.2498 | No | ||
91 | REST | 1500471 | 6689 | 0.041 | 0.2440 | No | ||
92 | ITPR2 | 5360128 | 6822 | 0.039 | 0.2373 | No | ||
93 | TEAD3 | 2320142 | 6923 | 0.037 | 0.2323 | No | ||
94 | DOK1 | 1050279 2680112 5220273 | 7069 | 0.034 | 0.2248 | No | ||
95 | FLI1 | 3990142 | 7143 | 0.032 | 0.2212 | No | ||
96 | SPARC | 1690086 | 7266 | 0.030 | 0.2149 | No | ||
97 | PTGIR | 2100563 | 7276 | 0.030 | 0.2147 | No | ||
98 | DIXDC1 | 6980435 | 7524 | 0.026 | 0.2016 | No | ||
99 | TYRO3 | 3130193 | 7525 | 0.026 | 0.2019 | No | ||
100 | ARHGEF12 | 3990195 | 8038 | 0.017 | 0.1743 | No | ||
101 | CRK | 1230162 4780128 | 8080 | 0.017 | 0.1723 | No | ||
102 | IL13 | 7040021 | 8194 | 0.015 | 0.1663 | No | ||
103 | ZNF35 | 670156 | 8289 | 0.014 | 0.1614 | No | ||
104 | ZNF205 | 6900022 | 8359 | 0.012 | 0.1578 | No | ||
105 | ANGPT1 | 3990368 5130288 6770035 | 8885 | 0.005 | 0.1293 | No | ||
106 | VIP | 2850647 | 8950 | 0.004 | 0.1259 | No | ||
107 | DOCK4 | 5910102 | 9173 | 0.001 | 0.1139 | No | ||
108 | RHOV | 5860100 | 9211 | 0.001 | 0.1119 | No | ||
109 | LRP5 | 2100397 3170484 | 9458 | -0.003 | 0.0986 | No | ||
110 | CTHRC1 | 4150020 | 9546 | -0.004 | 0.0939 | No | ||
111 | CPNE8 | 7040039 | 9735 | -0.007 | 0.0838 | No | ||
112 | ACTR3 | 1400497 | 9805 | -0.007 | 0.0801 | No | ||
113 | STRBP | 4210594 5360239 | 9823 | -0.008 | 0.0793 | No | ||
114 | MYH10 | 2640673 | 9871 | -0.008 | 0.0768 | No | ||
115 | AP2B1 | 1450184 2370148 3520139 4850593 | 10027 | -0.011 | 0.0685 | No | ||
116 | TWIST1 | 5130619 | 10033 | -0.011 | 0.0684 | No | ||
117 | TREML1 | 2510528 | 10391 | -0.016 | 0.0492 | No | ||
118 | GPR81 | 3190541 | 10560 | -0.019 | 0.0403 | No | ||
119 | PAX6 | 1190025 | 10695 | -0.021 | 0.0332 | No | ||
120 | TIMP4 | 6110433 | 10738 | -0.021 | 0.0312 | No | ||
121 | NPAS2 | 770670 | 10869 | -0.023 | 0.0244 | No | ||
122 | APBA1 | 3140487 | 11338 | -0.031 | -0.0007 | No | ||
123 | C1QTNF5 | 1690402 | 11370 | -0.031 | -0.0020 | No | ||
124 | PGF | 4810593 | 11737 | -0.038 | -0.0214 | No | ||
125 | ATOH8 | 4540204 | 11847 | -0.041 | -0.0269 | No | ||
126 | LOXL3 | 4010168 | 12097 | -0.046 | -0.0399 | No | ||
127 | EVX1 | 1980471 | 12099 | -0.046 | -0.0394 | No | ||
128 | CAMK2A | 1740333 1940112 4150292 | 12157 | -0.047 | -0.0420 | No | ||
129 | LOH11CR2A | 4480403 | 12192 | -0.048 | -0.0433 | No | ||
130 | SP3 | 3840338 | 12229 | -0.049 | -0.0447 | No | ||
131 | CLSPN | 2190239 2630687 5550632 | 12305 | -0.051 | -0.0482 | No | ||
132 | SHC3 | 2690398 | 12407 | -0.053 | -0.0531 | No | ||
133 | HOXA1 | 1190524 5420142 | 12476 | -0.055 | -0.0562 | No | ||
134 | STARD13 | 540722 | 12760 | -0.063 | -0.0708 | No | ||
135 | SLC39A11 | 5860687 | 12914 | -0.067 | -0.0784 | No | ||
136 | DLC1 | 1090632 6450594 | 12958 | -0.069 | -0.0800 | No | ||
137 | PAK3 | 4210136 | 13014 | -0.071 | -0.0822 | No | ||
138 | MMP3 | 2650368 2970056 | 13295 | -0.080 | -0.0964 | No | ||
139 | FUT10 | 6510603 | 13461 | -0.087 | -0.1044 | No | ||
140 | TUSC3 | 1690411 | 13502 | -0.089 | -0.1056 | No | ||
141 | LRMP | 6290193 | 13724 | -0.098 | -0.1165 | No | ||
142 | PPP1R12A | 4070066 4590162 | 13765 | -0.100 | -0.1176 | No | ||
143 | CENTD2 | 60408 2510156 6100494 | 13988 | -0.112 | -0.1284 | No | ||
144 | KLF12 | 1660095 4810288 5340546 6520286 | 14054 | -0.117 | -0.1306 | No | ||
145 | DPPA4 | 6860692 6900164 | 14079 | -0.118 | -0.1306 | No | ||
146 | CNKSR1 | 730528 3390672 | 14107 | -0.119 | -0.1307 | No | ||
147 | WNT9A | 3830711 | 14250 | -0.129 | -0.1370 | No | ||
148 | LDB2 | 5670441 6110170 | 14401 | -0.140 | -0.1436 | No | ||
149 | PCDH7 | 450398 4150040 | 14882 | -0.185 | -0.1676 | No | ||
150 | FURIN | 4120168 | 15017 | -0.199 | -0.1726 | No | ||
151 | E2F3 | 50162 460180 | 15049 | -0.203 | -0.1720 | No | ||
152 | DAB2IP | 3170064 6200441 | 15123 | -0.212 | -0.1736 | No | ||
153 | GPR44 | 4050452 | 15165 | -0.219 | -0.1734 | No | ||
154 | CANX | 4760402 | 15396 | -0.252 | -0.1831 | No | ||
155 | RASA3 | 2060465 | 15451 | -0.262 | -0.1831 | No | ||
156 | BCL2L2 | 2760692 6770739 | 15490 | -0.271 | -0.1822 | No | ||
157 | PITPNB | 5130039 | 15499 | -0.272 | -0.1796 | No | ||
158 | FYN | 2100468 4760520 4850687 | 15696 | -0.311 | -0.1867 | No | ||
159 | GNG11 | 4010142 | 15729 | -0.319 | -0.1849 | No | ||
160 | TRPC4AP | 840520 1660402 | 15908 | -0.359 | -0.1906 | No | ||
161 | ATP5H | 670438 | 16050 | -0.394 | -0.1938 | No | ||
162 | TCERG1 | 2350551 4540397 5220746 | 16250 | -0.445 | -0.1997 | No | ||
163 | TCF12 | 3610324 7000156 | 16359 | -0.484 | -0.2002 | No | ||
164 | CITED2 | 5670114 5130088 | 16426 | -0.502 | -0.1982 | No | ||
165 | DLGAP4 | 4570672 5690161 | 16441 | -0.506 | -0.1933 | No | ||
166 | IGF1 | 1990193 3130377 3290280 | 16886 | -0.674 | -0.2099 | No | ||
167 | RAC1 | 4810687 | 17179 | -0.806 | -0.2167 | No | ||
168 | VDAC2 | 7000215 | 17200 | -0.820 | -0.2087 | No | ||
169 | ARHGAP4 | 1940022 | 17241 | -0.836 | -0.2016 | No | ||
170 | CALM2 | 6620463 | 17272 | -0.852 | -0.1937 | No | ||
171 | RGS12 | 1190082 5390369 | 17392 | -0.916 | -0.1900 | No | ||
172 | S100A9 | 7050528 | 17444 | -0.953 | -0.1821 | No | ||
173 | UTX | 2900017 6770452 | 17446 | -0.954 | -0.1716 | No | ||
174 | SESTD1 | 1090333 3780593 | 17457 | -0.957 | -0.1614 | No | ||
175 | ELMO1 | 110338 1190451 1580148 1850609 2350706 2370369 2450129 3840113 4150184 4280079 6290066 6380435 6770494 7100180 | 17483 | -0.970 | -0.1520 | No | ||
176 | CTCF | 5340017 | 17696 | -1.070 | -0.1516 | No | ||
177 | SPATA6 | 4590373 | 17738 | -1.097 | -0.1416 | No | ||
178 | CKB | 4560632 | 18162 | -1.473 | -0.1482 | No | ||
179 | LST1 | 5420372 | 18328 | -1.714 | -0.1380 | No | ||
180 | VCL | 4120487 | 18343 | -1.734 | -0.1195 | No | ||
181 | USP3 | 2060332 | 18483 | -2.154 | -0.1030 | No | ||
182 | IMPDH1 | 3190735 7050546 | 18539 | -2.354 | -0.0798 | No | ||
183 | S100A10 | 6350010 | 18545 | -2.418 | -0.0532 | No | ||
184 | NR1D1 | 2360471 770746 6590204 | 18562 | -2.528 | -0.0259 | No | ||
185 | TYROBP | 2230020 | 18566 | -2.584 | 0.0027 | No |