Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #wtNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_wtNotch.cls#wtNotch_versus_absentNotch |
Upregulated in class | wtNotch |
GeneSet | V$ETS1_B |
Enrichment Score (ES) | 0.44584408 |
Normalized Enrichment Score (NES) | 1.395069 |
Nominal p-value | 0.0023148148 |
FDR q-value | 1.0 |
FWER p-Value | 0.996 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | POU2AF1 | 5690242 | 1 | 4.937 | 0.0577 | Yes | ||
2 | GIT2 | 6040039 6770181 | 107 | 2.094 | 0.0764 | Yes | ||
3 | PDLIM2 | 2450603 2810551 3830040 4670164 | 121 | 2.043 | 0.0996 | Yes | ||
4 | FBXO36 | 1410086 | 156 | 1.921 | 0.1202 | Yes | ||
5 | UBE2L3 | 1690707 5900242 | 222 | 1.745 | 0.1371 | Yes | ||
6 | HMGA1 | 6580408 | 293 | 1.609 | 0.1521 | Yes | ||
7 | LCP1 | 4280397 | 310 | 1.578 | 0.1697 | Yes | ||
8 | DEF6 | 840593 | 324 | 1.555 | 0.1872 | Yes | ||
9 | RNF31 | 110035 | 332 | 1.543 | 0.2048 | Yes | ||
10 | RNF40 | 3610397 | 508 | 1.306 | 0.2106 | Yes | ||
11 | PPP1R9B | 3130619 | 585 | 1.227 | 0.2208 | Yes | ||
12 | TRIM41 | 4070019 6110670 | 609 | 1.207 | 0.2337 | Yes | ||
13 | TPP2 | 3850093 | 631 | 1.190 | 0.2465 | Yes | ||
14 | PSME2 | 4850086 | 669 | 1.162 | 0.2580 | Yes | ||
15 | KCNAB2 | 4850315 | 672 | 1.160 | 0.2715 | Yes | ||
16 | ROCK1 | 130044 | 714 | 1.127 | 0.2824 | Yes | ||
17 | JUNB | 4230048 | 795 | 1.073 | 0.2906 | Yes | ||
18 | POLD4 | 2320082 | 850 | 1.024 | 0.2997 | Yes | ||
19 | BAZ2A | 730184 | 852 | 1.024 | 0.3116 | Yes | ||
20 | HNRPK | 1190348 2060411 2570092 6840551 | 894 | 1.002 | 0.3211 | Yes | ||
21 | DMTF1 | 5910047 1570497 2480100 6620239 | 916 | 0.998 | 0.3316 | Yes | ||
22 | TNNI2 | 5910739 | 980 | 0.963 | 0.3394 | Yes | ||
23 | HIC1 | 2650142 | 981 | 0.963 | 0.3507 | Yes | ||
24 | SRPR | 6590647 6370114 | 1074 | 0.917 | 0.3564 | Yes | ||
25 | CORO1A | 3140609 3190020 3190037 | 1148 | 0.875 | 0.3627 | Yes | ||
26 | ITPR3 | 4010632 | 1153 | 0.873 | 0.3727 | Yes | ||
27 | SH3BGRL | 2060110 | 1238 | 0.822 | 0.3777 | Yes | ||
28 | SEPT1 | 3290546 | 1302 | 0.793 | 0.3836 | Yes | ||
29 | RGMA | 2450711 | 1415 | 0.749 | 0.3863 | Yes | ||
30 | ROD1 | 2060324 3140332 | 1442 | 0.735 | 0.3935 | Yes | ||
31 | NEDD8 | 2350722 | 1448 | 0.733 | 0.4017 | Yes | ||
32 | BIN3 | 380551 | 1526 | 0.700 | 0.4058 | Yes | ||
33 | ELOVL6 | 5340746 | 1527 | 0.700 | 0.4139 | Yes | ||
34 | CAMK1D | 1660100 2350309 | 1609 | 0.667 | 0.4173 | Yes | ||
35 | TGIF2 | 3840364 4050520 | 1638 | 0.655 | 0.4235 | Yes | ||
36 | GTF2B | 6860685 | 1770 | 0.604 | 0.4234 | Yes | ||
37 | RGS3 | 60670 540736 1340180 1500369 3390735 4010131 4610402 6380114 | 1782 | 0.602 | 0.4299 | Yes | ||
38 | PIK3CG | 5890110 | 1823 | 0.589 | 0.4346 | Yes | ||
39 | SLC9A3R1 | 6020373 | 1881 | 0.568 | 0.4381 | Yes | ||
40 | MAGED1 | 6650332 | 1913 | 0.561 | 0.4430 | Yes | ||
41 | IKBKB | 6840072 | 1993 | 0.532 | 0.4450 | Yes | ||
42 | ADAM11 | 1050008 3130494 | 2140 | 0.486 | 0.4427 | Yes | ||
43 | LYL1 | 2900242 | 2186 | 0.476 | 0.4458 | Yes | ||
44 | ESM1 | 1410594 | 2329 | 0.434 | 0.4432 | No | ||
45 | TGFB3 | 1070041 | 2466 | 0.396 | 0.4405 | No | ||
46 | ARPP-19 | 5700025 | 2671 | 0.350 | 0.4335 | No | ||
47 | LCK | 3360142 | 2730 | 0.337 | 0.4343 | No | ||
48 | MAP4K2 | 4200037 | 2766 | 0.331 | 0.4363 | No | ||
49 | ORC4L | 4230538 5550288 | 2855 | 0.313 | 0.4351 | No | ||
50 | CBLB | 3520465 4670348 | 3112 | 0.269 | 0.4244 | No | ||
51 | GALNT2 | 2260279 4060239 | 3121 | 0.268 | 0.4271 | No | ||
52 | SPRED2 | 510138 540195 | 3150 | 0.261 | 0.4286 | No | ||
53 | DPP3 | 2680725 3780670 | 3184 | 0.255 | 0.4298 | No | ||
54 | NT5C2 | 4280735 4670528 | 3333 | 0.234 | 0.4245 | No | ||
55 | RGS14 | 380086 | 3517 | 0.210 | 0.4171 | No | ||
56 | CACNA1D | 1740315 4730731 | 3656 | 0.194 | 0.4119 | No | ||
57 | HM13 | 60463 940711 4850609 | 3689 | 0.190 | 0.4123 | No | ||
58 | MTPN | 3940167 | 3844 | 0.176 | 0.4060 | No | ||
59 | STK10 | 2760010 3940605 | 3900 | 0.170 | 0.4050 | No | ||
60 | SEMA4C | 1980315 | 3948 | 0.166 | 0.4044 | No | ||
61 | SLC16A2 | 6660739 | 4003 | 0.161 | 0.4034 | No | ||
62 | VPS39 | 50332 | 4098 | 0.152 | 0.4001 | No | ||
63 | TBN | 3290270 | 4100 | 0.152 | 0.4018 | No | ||
64 | MADD | 6100725 7000088 | 4266 | 0.139 | 0.3945 | No | ||
65 | GMPR2 | 4920204 | 4627 | 0.115 | 0.3763 | No | ||
66 | BDKRB2 | 4780706 | 4684 | 0.113 | 0.3746 | No | ||
67 | SLC12A4 | 130731 | 4693 | 0.112 | 0.3754 | No | ||
68 | STK16 | 1740154 | 5044 | 0.093 | 0.3575 | No | ||
69 | UBE2R2 | 1230504 | 5325 | 0.081 | 0.3433 | No | ||
70 | SEC24C | 6980707 | 5398 | 0.078 | 0.3403 | No | ||
71 | OLFM1 | 3360161 5570066 | 5415 | 0.078 | 0.3404 | No | ||
72 | POU3F4 | 870274 | 5447 | 0.077 | 0.3396 | No | ||
73 | HOXC4 | 1940193 | 5550 | 0.073 | 0.3349 | No | ||
74 | BMP4 | 380113 | 5651 | 0.069 | 0.3303 | No | ||
75 | CAST | 3850082 5420671 6200156 | 5749 | 0.065 | 0.3258 | No | ||
76 | ADAMTS4 | 430435 | 5816 | 0.063 | 0.3229 | No | ||
77 | KCNQ1 | 1580050 6860441 | 5903 | 0.061 | 0.3190 | No | ||
78 | LYN | 6040600 | 6066 | 0.056 | 0.3108 | No | ||
79 | RNF12 | 6860717 | 6104 | 0.055 | 0.3095 | No | ||
80 | FLNC | 2360048 5050270 | 6135 | 0.055 | 0.3085 | No | ||
81 | GPR150 | 2570440 | 6257 | 0.051 | 0.3025 | No | ||
82 | PLCB2 | 360132 | 6384 | 0.048 | 0.2963 | No | ||
83 | GJA5 | 60142 1740008 1740026 | 6418 | 0.047 | 0.2950 | No | ||
84 | HOXA10 | 6110397 7100458 | 6508 | 0.045 | 0.2907 | No | ||
85 | IL12B | 460008 | 6572 | 0.044 | 0.2878 | No | ||
86 | ITPR2 | 5360128 | 6822 | 0.039 | 0.2748 | No | ||
87 | SOST | 1170195 | 6899 | 0.037 | 0.2711 | No | ||
88 | DOK1 | 1050279 2680112 5220273 | 7069 | 0.034 | 0.2623 | No | ||
89 | AMD1 | 6290128 | 7149 | 0.032 | 0.2584 | No | ||
90 | ADAM15 | 5890707 | 7311 | 0.029 | 0.2500 | No | ||
91 | DKK2 | 3610433 | 7498 | 0.026 | 0.2402 | No | ||
92 | TYRO3 | 3130193 | 7525 | 0.026 | 0.2391 | No | ||
93 | UBTF | 4210450 6840403 | 7583 | 0.025 | 0.2363 | No | ||
94 | PML | 50093 2190435 2450402 3840082 | 7651 | 0.024 | 0.2329 | No | ||
95 | LCP2 | 2680066 6650707 | 7738 | 0.022 | 0.2285 | No | ||
96 | E2F5 | 5860575 | 8040 | 0.017 | 0.2124 | No | ||
97 | IL13 | 7040021 | 8194 | 0.015 | 0.2043 | No | ||
98 | ZNF35 | 670156 | 8289 | 0.014 | 0.1994 | No | ||
99 | ZNF205 | 6900022 | 8359 | 0.012 | 0.1958 | No | ||
100 | DHH | 2120433 | 8474 | 0.011 | 0.1897 | No | ||
101 | FOSL1 | 430021 | 8666 | 0.008 | 0.1794 | No | ||
102 | IL1RAPL2 | 1940075 | 8738 | 0.007 | 0.1757 | No | ||
103 | TENC1 | 1980403 7050575 | 8799 | 0.006 | 0.1725 | No | ||
104 | RHOV | 5860100 | 9211 | 0.001 | 0.1502 | No | ||
105 | CPNE8 | 7040039 | 9735 | -0.007 | 0.1219 | No | ||
106 | CHES1 | 4570121 5700162 | 9767 | -0.007 | 0.1203 | No | ||
107 | MYH10 | 2640673 | 9871 | -0.008 | 0.1148 | No | ||
108 | TWIST1 | 5130619 | 10033 | -0.011 | 0.1062 | No | ||
109 | PAX6 | 1190025 | 10695 | -0.021 | 0.0706 | No | ||
110 | TIMP4 | 6110433 | 10738 | -0.021 | 0.0686 | No | ||
111 | KIF1C | 2480484 | 10781 | -0.022 | 0.0666 | No | ||
112 | CRADD | 6770520 | 11077 | -0.027 | 0.0509 | No | ||
113 | MLLT7 | 4480707 | 11189 | -0.029 | 0.0452 | No | ||
114 | APBA1 | 3140487 | 11338 | -0.031 | 0.0375 | No | ||
115 | PTPN11 | 2230100 2470180 6100528 | 11527 | -0.034 | 0.0277 | No | ||
116 | NEDD4 | 460736 1190280 | 11741 | -0.039 | 0.0166 | No | ||
117 | RASA2 | 7100706 | 12082 | -0.045 | -0.0013 | No | ||
118 | LOXL3 | 4010168 | 12097 | -0.046 | -0.0015 | No | ||
119 | LRRN3 | 1450133 | 12106 | -0.046 | -0.0014 | No | ||
120 | ELK3 | 460377 1400762 3710497 | 12124 | -0.046 | -0.0018 | No | ||
121 | SHC3 | 2690398 | 12407 | -0.053 | -0.0165 | No | ||
122 | HOXA1 | 1190524 5420142 | 12476 | -0.055 | -0.0195 | No | ||
123 | LIF | 1410373 2060129 3990338 | 12546 | -0.056 | -0.0226 | No | ||
124 | KLF13 | 4670563 | 12746 | -0.062 | -0.0327 | No | ||
125 | STARD13 | 540722 | 12760 | -0.063 | -0.0326 | No | ||
126 | SNCAIP | 4010551 | 12820 | -0.064 | -0.0351 | No | ||
127 | CSF2 | 1660593 | 12835 | -0.065 | -0.0351 | No | ||
128 | ITGA11 | 1740112 6590110 | 12907 | -0.067 | -0.0382 | No | ||
129 | SLC39A11 | 5860687 | 12914 | -0.067 | -0.0377 | No | ||
130 | DLC1 | 1090632 6450594 | 12958 | -0.069 | -0.0392 | No | ||
131 | MMP3 | 2650368 2970056 | 13295 | -0.080 | -0.0565 | No | ||
132 | KCND1 | 6860278 | 13521 | -0.089 | -0.0677 | No | ||
133 | GLP2R | 4150577 5290273 7050095 | 13533 | -0.090 | -0.0672 | No | ||
134 | EPN3 | 2350592 | 13537 | -0.090 | -0.0663 | No | ||
135 | GPR120 | 2350398 | 13577 | -0.091 | -0.0674 | No | ||
136 | ETF1 | 6770075 | 13879 | -0.106 | -0.0825 | No | ||
137 | KLF12 | 1660095 4810288 5340546 6520286 | 14054 | -0.117 | -0.0906 | No | ||
138 | DPPA4 | 6860692 6900164 | 14079 | -0.118 | -0.0905 | No | ||
139 | CNKSR1 | 730528 3390672 | 14107 | -0.119 | -0.0905 | No | ||
140 | SLC7A1 | 2450193 2710241 | 14147 | -0.122 | -0.0912 | No | ||
141 | TNFSF11 | 6350204 | 14200 | -0.125 | -0.0926 | No | ||
142 | CENTB1 | 2120093 | 14228 | -0.127 | -0.0926 | No | ||
143 | ARHGAP15 | 610446 2340327 2900438 | 14870 | -0.183 | -0.1252 | No | ||
144 | PCDH7 | 450398 4150040 | 14882 | -0.185 | -0.1236 | No | ||
145 | NRG1 | 1050332 | 14898 | -0.187 | -0.1223 | No | ||
146 | FURIN | 4120168 | 15017 | -0.199 | -0.1263 | No | ||
147 | PDGFB | 3060440 6370008 | 15042 | -0.203 | -0.1253 | No | ||
148 | E2F3 | 50162 460180 | 15049 | -0.203 | -0.1232 | No | ||
149 | DAB2IP | 3170064 6200441 | 15123 | -0.212 | -0.1247 | No | ||
150 | LAG3 | 6860112 | 15144 | -0.215 | -0.1233 | No | ||
151 | SPRED1 | 6940706 | 15259 | -0.231 | -0.1268 | No | ||
152 | CD79A | 3450563 | 15327 | -0.242 | -0.1276 | No | ||
153 | CANX | 4760402 | 15396 | -0.252 | -0.1283 | No | ||
154 | BCL2L2 | 2760692 6770739 | 15490 | -0.271 | -0.1302 | No | ||
155 | SLC9A9 | 1940309 | 15504 | -0.273 | -0.1277 | No | ||
156 | RAP2C | 1690132 | 15592 | -0.288 | -0.1290 | No | ||
157 | SLC4A1AP | 3190576 | 15690 | -0.308 | -0.1307 | No | ||
158 | FYN | 2100468 4760520 4850687 | 15696 | -0.311 | -0.1273 | No | ||
159 | RPS3 | 1570017 2370170 | 15834 | -0.342 | -0.1308 | No | ||
160 | HYAL2 | 1500152 | 15921 | -0.361 | -0.1312 | No | ||
161 | RUVBL1 | 4280239 5080273 | 15978 | -0.376 | -0.1299 | No | ||
162 | CAP1 | 2650278 | 16144 | -0.417 | -0.1339 | No | ||
163 | DLGAP4 | 4570672 5690161 | 16441 | -0.506 | -0.1441 | No | ||
164 | ITPKB | 2900195 7100039 | 16516 | -0.533 | -0.1419 | No | ||
165 | MAP4K4 | 2360059 | 16829 | -0.647 | -0.1512 | No | ||
166 | ETV6 | 610524 | 16866 | -0.666 | -0.1454 | No | ||
167 | NME1 | 770014 | 16924 | -0.688 | -0.1404 | No | ||
168 | AXUD1 | 1230053 | 17152 | -0.791 | -0.1435 | No | ||
169 | SLC30A7 | 2230463 | 17267 | -0.848 | -0.1398 | No | ||
170 | ELMO1 | 110338 1190451 1580148 1850609 2350706 2370369 2450129 3840113 4150184 4280079 6290066 6380435 6770494 7100180 | 17483 | -0.970 | -0.1401 | No | ||
171 | NDUFS2 | 4850020 6200402 | 17485 | -0.970 | -0.1288 | No | ||
172 | PABPC1 | 2650180 2690253 6020632 1990270 | 17797 | -1.149 | -0.1323 | No | ||
173 | HSD3B7 | 1410129 | 18028 | -1.320 | -0.1293 | No | ||
174 | LUC7L | 6040156 6110411 | 18072 | -1.369 | -0.1156 | No | ||
175 | ABCG1 | 60692 | 18129 | -1.423 | -0.1020 | No | ||
176 | EXTL2 | 5050433 | 18262 | -1.585 | -0.0907 | No | ||
177 | FOXP1 | 6510433 | 18275 | -1.604 | -0.0726 | No | ||
178 | IMPDH1 | 3190735 7050546 | 18539 | -2.354 | -0.0593 | No | ||
179 | S100A10 | 6350010 | 18545 | -2.418 | -0.0313 | No | ||
180 | PTK2 | 1780148 | 18588 | -3.004 | 0.0015 | No |