Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #wtNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_wtNotch.cls#wtNotch_versus_absentNotch |
Upregulated in class | absentNotch |
GeneSet | V$E2F_Q4 |
Enrichment Score (ES) | -0.5099185 |
Normalized Enrichment Score (NES) | -1.5159179 |
Nominal p-value | 0.0016891892 |
FDR q-value | 0.16302995 |
FWER p-Value | 0.844 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | RRM2 | 6350059 6940162 | 318 | 1.562 | 0.0043 | No | ||
2 | USP52 | 3710215 6380133 | 392 | 1.453 | 0.0203 | No | ||
3 | ATF5 | 5670685 | 587 | 1.226 | 0.0266 | No | ||
4 | HMGN2 | 3140091 | 762 | 1.096 | 0.0323 | No | ||
5 | SFRS10 | 6130528 6400438 7040112 | 827 | 1.047 | 0.0432 | No | ||
6 | DNMT1 | 2260097 | 1304 | 0.791 | 0.0283 | No | ||
7 | CDT1 | 3780682 | 1385 | 0.761 | 0.0344 | No | ||
8 | SYNGR4 | 6520450 | 1416 | 0.749 | 0.0431 | No | ||
9 | DNAJC11 | 360465 3390215 | 1489 | 0.719 | 0.0491 | No | ||
10 | POLD1 | 4830026 | 1667 | 0.641 | 0.0483 | No | ||
11 | PHF5A | 2690519 | 1760 | 0.607 | 0.0517 | No | ||
12 | PHF13 | 450435 | 1868 | 0.572 | 0.0538 | No | ||
13 | RANBP1 | 430215 1090180 | 2036 | 0.519 | 0.0519 | No | ||
14 | PRPS1 | 6350129 | 2061 | 0.513 | 0.0576 | No | ||
15 | RPS6KA5 | 2120563 7040546 | 2150 | 0.485 | 0.0595 | No | ||
16 | HIST1H2BK | 6130433 | 2192 | 0.474 | 0.0638 | No | ||
17 | SFRS7 | 2760408 | 2235 | 0.461 | 0.0679 | No | ||
18 | DDB2 | 3520341 4610168 4850184 4920717 | 2253 | 0.458 | 0.0733 | No | ||
19 | MAZ | 3360121 6940750 | 2365 | 0.423 | 0.0731 | No | ||
20 | ERBB2IP | 580253 1090672 | 2378 | 0.419 | 0.0782 | No | ||
21 | POLR2A | 5220647 | 2468 | 0.395 | 0.0788 | No | ||
22 | SUMO1 | 1990364 2760338 6380195 | 2474 | 0.393 | 0.0839 | No | ||
23 | CDC45L | 70537 3130114 | 2538 | 0.378 | 0.0857 | No | ||
24 | HCN3 | 3940438 6840750 | 2541 | 0.377 | 0.0908 | No | ||
25 | TBX6 | 4730139 6840647 | 2683 | 0.346 | 0.0879 | No | ||
26 | RAD51 | 6110450 6980280 | 3044 | 0.281 | 0.0723 | No | ||
27 | ARID4A | 520156 1050707 | 3092 | 0.274 | 0.0735 | No | ||
28 | STAG2 | 4540132 | 3252 | 0.245 | 0.0683 | No | ||
29 | SEMA5A | 6200110 6520435 | 3429 | 0.221 | 0.0618 | No | ||
30 | FHOD1 | 2680279 | 3605 | 0.199 | 0.0550 | No | ||
31 | NCL | 2360463 4540279 | 3682 | 0.191 | 0.0535 | No | ||
32 | HNRPA1 | 4670398 5050687 | 3753 | 0.184 | 0.0523 | No | ||
33 | KCND2 | 1170128 2100112 | 3779 | 0.182 | 0.0534 | No | ||
34 | MXD3 | 6220014 | 3859 | 0.174 | 0.0515 | No | ||
35 | GPRC5B | 2760114 | 3924 | 0.168 | 0.0504 | No | ||
36 | CORT | 360008 2340092 | 4478 | 0.124 | 0.0221 | No | ||
37 | ING3 | 110438 2060390 | 4523 | 0.121 | 0.0214 | No | ||
38 | CDC6 | 4570296 5360600 | 4536 | 0.120 | 0.0224 | No | ||
39 | CCNT1 | 2450563 5390184 | 4547 | 0.120 | 0.0235 | No | ||
40 | HNRPR | 2320440 2900601 4610008 | 5017 | 0.094 | -0.0006 | No | ||
41 | NRP2 | 4070400 5860041 6650446 | 5139 | 0.089 | -0.0059 | No | ||
42 | HS6ST3 | 5910138 | 5144 | 0.089 | -0.0049 | No | ||
43 | FBXO5 | 2630551 | 5159 | 0.088 | -0.0045 | No | ||
44 | GMNN | 2630148 | 5396 | 0.078 | -0.0162 | No | ||
45 | PHF15 | 6550066 6860673 | 5863 | 0.062 | -0.0406 | No | ||
46 | INSM1 | 3450671 | 6420 | 0.047 | -0.0700 | No | ||
47 | TOPBP1 | 6020333 | 6541 | 0.044 | -0.0759 | No | ||
48 | TREX2 | 4920707 | 6568 | 0.044 | -0.0767 | No | ||
49 | STK35 | 2360121 | 6835 | 0.038 | -0.0906 | No | ||
50 | GRIA4 | 2640131 | 6933 | 0.037 | -0.0954 | No | ||
51 | NUP153 | 7000452 | 7024 | 0.035 | -0.0998 | No | ||
52 | TYRO3 | 3130193 | 7525 | 0.026 | -0.1265 | No | ||
53 | HNRPD | 4120021 | 7947 | 0.019 | -0.1490 | No | ||
54 | CRK | 1230162 4780128 | 8080 | 0.017 | -0.1559 | No | ||
55 | NELL2 | 2340725 4280301 5420008 | 8279 | 0.014 | -0.1665 | No | ||
56 | EPHB1 | 4610056 | 8294 | 0.014 | -0.1670 | No | ||
57 | POLE2 | 6110041 | 8612 | 0.009 | -0.1841 | No | ||
58 | ILF3 | 940722 3190647 6520110 | 8663 | 0.008 | -0.1867 | No | ||
59 | IPO7 | 2190746 | 8681 | 0.008 | -0.1875 | No | ||
60 | ABI2 | 940368 4200092 | 8717 | 0.007 | -0.1893 | No | ||
61 | ZBTB4 | 6450441 | 9073 | 0.002 | -0.2085 | No | ||
62 | CASP8AP2 | 5910593 | 9128 | 0.002 | -0.2114 | No | ||
63 | MCM7 | 3290292 5220056 | 9312 | -0.001 | -0.2213 | No | ||
64 | DNAJC9 | 6130019 | 9348 | -0.001 | -0.2232 | No | ||
65 | WNT3 | 2360685 | 9398 | -0.002 | -0.2258 | No | ||
66 | ARHGAP6 | 2060121 | 9812 | -0.008 | -0.2481 | No | ||
67 | MYH10 | 2640673 | 9871 | -0.008 | -0.2511 | No | ||
68 | PODN | 3710068 | 9972 | -0.010 | -0.2564 | No | ||
69 | CBX5 | 3830072 6290167 | 10003 | -0.010 | -0.2579 | No | ||
70 | RHD | 4050168 | 10487 | -0.018 | -0.2838 | No | ||
71 | GABRB3 | 4150164 | 10569 | -0.019 | -0.2879 | No | ||
72 | PAX6 | 1190025 | 10695 | -0.021 | -0.2944 | No | ||
73 | ACBD6 | 4200446 | 10930 | -0.024 | -0.3067 | No | ||
74 | MCM8 | 6130743 | 11125 | -0.027 | -0.3169 | No | ||
75 | HOXC10 | 5360170 | 11438 | -0.033 | -0.3333 | No | ||
76 | YBX2 | 3520441 | 11472 | -0.033 | -0.3346 | No | ||
77 | CHD2 | 4070039 | 11727 | -0.038 | -0.3479 | No | ||
78 | E2F7 | 4200056 | 12149 | -0.047 | -0.3700 | No | ||
79 | ASXL2 | 130670 | 12176 | -0.048 | -0.3708 | No | ||
80 | SP3 | 3840338 | 12229 | -0.049 | -0.3729 | No | ||
81 | CLSPN | 2190239 2630687 5550632 | 12305 | -0.051 | -0.3763 | No | ||
82 | FMO4 | 360735 | 12707 | -0.061 | -0.3972 | No | ||
83 | DMD | 1740041 3990332 | 12741 | -0.062 | -0.3981 | No | ||
84 | SMAD6 | 870504 | 13179 | -0.076 | -0.4207 | No | ||
85 | PAQR4 | 730736 | 13188 | -0.076 | -0.4201 | No | ||
86 | STAG1 | 1190300 1400722 4590100 | 13358 | -0.083 | -0.4281 | No | ||
87 | PCSK1 | 2350148 | 13404 | -0.085 | -0.4294 | No | ||
88 | UXT | 110019 5080066 | 13574 | -0.091 | -0.4373 | No | ||
89 | PVRL1 | 2570167 5220519 5890500 3190309 | 13799 | -0.101 | -0.4480 | No | ||
90 | WEE1 | 3390070 | 13909 | -0.107 | -0.4524 | No | ||
91 | HNRPUL1 | 2120008 4920408 5570180 6370609 6770403 | 14128 | -0.121 | -0.4626 | No | ||
92 | RQCD1 | 1850139 | 14282 | -0.131 | -0.4691 | No | ||
93 | SNRPD1 | 4480162 | 14410 | -0.140 | -0.4740 | No | ||
94 | PRKDC | 1400072 4230541 | 14641 | -0.161 | -0.4843 | No | ||
95 | ADAMTS2 | 2650025 6370133 6840670 | 14747 | -0.169 | -0.4876 | No | ||
96 | SLC6A4 | 2230372 | 14748 | -0.169 | -0.4853 | No | ||
97 | KCNA6 | 450291 1400086 1660291 2470576 | 14806 | -0.174 | -0.4860 | No | ||
98 | UFD1L | 870020 | 14930 | -0.191 | -0.4900 | No | ||
99 | E2F3 | 50162 460180 | 15049 | -0.203 | -0.4936 | No | ||
100 | EED | 2320373 | 15059 | -0.204 | -0.4913 | No | ||
101 | USP37 | 2470433 | 15128 | -0.212 | -0.4921 | No | ||
102 | EFNA5 | 460707 2190519 | 15207 | -0.225 | -0.4932 | No | ||
103 | JPH1 | 610739 | 15320 | -0.240 | -0.4960 | No | ||
104 | HIRA | 4480609 5270167 | 15399 | -0.252 | -0.4967 | No | ||
105 | EZH2 | 6130605 6380524 | 15457 | -0.264 | -0.4962 | No | ||
106 | HIST1H2AH | 3710333 | 15665 | -0.303 | -0.5032 | No | ||
107 | POLA2 | 940519 | 15687 | -0.308 | -0.5001 | No | ||
108 | ATAD2 | 870242 2260687 | 15795 | -0.334 | -0.5013 | No | ||
109 | BRMS1L | 6110609 | 15850 | -0.345 | -0.4995 | No | ||
110 | EPC1 | 1570050 5290095 6900193 | 15993 | -0.380 | -0.5020 | No | ||
111 | MCM2 | 5050139 | 16009 | -0.385 | -0.4975 | No | ||
112 | MCM6 | 60092 540181 6510110 | 16029 | -0.390 | -0.4932 | No | ||
113 | PPP1CC | 6380300 2510647 | 16339 | -0.479 | -0.5033 | Yes | ||
114 | NOLC1 | 2350195 | 16397 | -0.494 | -0.4996 | Yes | ||
115 | SLC38A1 | 520465 | 16424 | -0.502 | -0.4941 | Yes | ||
116 | MRPL40 | 2370215 | 16472 | -0.515 | -0.4896 | Yes | ||
117 | PPP1R8 | 6290292 | 16533 | -0.540 | -0.4854 | Yes | ||
118 | RAB11B | 3990609 | 16544 | -0.544 | -0.4785 | Yes | ||
119 | AK2 | 4590458 4760195 6110097 | 16550 | -0.545 | -0.4712 | Yes | ||
120 | MCM4 | 2760673 5420711 | 16712 | -0.605 | -0.4717 | Yes | ||
121 | PIM1 | 630047 | 16761 | -0.621 | -0.4657 | Yes | ||
122 | SLCO3A1 | 1050408 2370156 6110072 | 16768 | -0.624 | -0.4575 | Yes | ||
123 | UNG | 3130110 6100364 | 16876 | -0.670 | -0.4540 | Yes | ||
124 | MCM3 | 5570068 | 16965 | -0.703 | -0.4491 | Yes | ||
125 | ACO2 | 4230600 | 17123 | -0.778 | -0.4470 | Yes | ||
126 | MSH2 | 6180273 | 17144 | -0.787 | -0.4372 | Yes | ||
127 | CDCA7 | 3060097 | 17155 | -0.793 | -0.4269 | Yes | ||
128 | PCNA | 940754 | 17203 | -0.821 | -0.4181 | Yes | ||
129 | KPNB1 | 1690138 | 17230 | -0.833 | -0.4081 | Yes | ||
130 | H2AFZ | 1470168 | 17329 | -0.879 | -0.4013 | Yes | ||
131 | POLE4 | 6860097 | 17428 | -0.944 | -0.3936 | Yes | ||
132 | SFRS2 | 50707 380593 | 17526 | -0.992 | -0.3852 | Yes | ||
133 | FANCD2 | 1850280 6840348 | 17580 | -1.003 | -0.3743 | Yes | ||
134 | NUP62 | 1240128 | 17593 | -1.009 | -0.3611 | Yes | ||
135 | POLD3 | 6400278 | 17691 | -1.066 | -0.3516 | Yes | ||
136 | CTCF | 5340017 | 17696 | -1.070 | -0.3371 | Yes | ||
137 | RBL1 | 3130372 | 17703 | -1.074 | -0.3227 | Yes | ||
138 | CDC25A | 3800184 | 17772 | -1.122 | -0.3110 | Yes | ||
139 | PHC1 | 520195 | 17845 | -1.184 | -0.2986 | Yes | ||
140 | HTF9C | 3190048 4120132 | 17852 | -1.188 | -0.2826 | Yes | ||
141 | IL4I1 | 3190161 | 17853 | -1.188 | -0.2662 | Yes | ||
142 | NASP | 2260139 2940369 5130707 | 17862 | -1.193 | -0.2503 | Yes | ||
143 | ALDH6A1 | 1770746 | 17943 | -1.249 | -0.2374 | Yes | ||
144 | SFRS1 | 2360440 | 18010 | -1.309 | -0.2230 | Yes | ||
145 | STMN1 | 1990717 | 18068 | -1.364 | -0.2073 | Yes | ||
146 | ZCCHC8 | 2260332 2350487 | 18085 | -1.377 | -0.1893 | Yes | ||
147 | E2F1 | 5360093 | 18222 | -1.543 | -0.1754 | Yes | ||
148 | AP4M1 | 70609 3440128 | 18291 | -1.638 | -0.1566 | Yes | ||
149 | GSPT1 | 5420050 | 18376 | -1.825 | -0.1360 | Yes | ||
150 | UGCGL1 | 4230072 | 18385 | -1.856 | -0.1109 | Yes | ||
151 | DCK | 6900411 | 18435 | -1.963 | -0.0866 | Yes | ||
152 | PPM1D | 1690193 | 18460 | -2.052 | -0.0596 | Yes | ||
153 | SOAT1 | 1190019 | 18490 | -2.177 | -0.0313 | Yes | ||
154 | TMPO | 4050494 | 18577 | -2.767 | 0.0021 | Yes |