Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #wtNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_wtNotch.cls#wtNotch_versus_absentNotch |
Upregulated in class | absentNotch |
GeneSet | V$E2F1DP2_01 |
Enrichment Score (ES) | -0.492247 |
Normalized Enrichment Score (NES) | -1.4920157 |
Nominal p-value | 0.001754386 |
FDR q-value | 0.16329655 |
FWER p-Value | 0.918 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | MSH5 | 1340019 4730333 | 193 | 1.810 | 0.0120 | No | ||
2 | HMGA1 | 6580408 | 293 | 1.609 | 0.0267 | No | ||
3 | SUV39H1 | 630112 | 305 | 1.583 | 0.0457 | No | ||
4 | RRM2 | 6350059 6940162 | 318 | 1.562 | 0.0645 | No | ||
5 | PRPS2 | 3140707 | 387 | 1.459 | 0.0789 | No | ||
6 | USP52 | 3710215 6380133 | 392 | 1.453 | 0.0967 | No | ||
7 | TLE3 | 580040 4730121 | 549 | 1.268 | 0.1040 | No | ||
8 | ATF5 | 5670685 | 587 | 1.226 | 0.1172 | No | ||
9 | SFRS10 | 6130528 6400438 7040112 | 827 | 1.047 | 0.1173 | No | ||
10 | DNMT1 | 2260097 | 1304 | 0.791 | 0.1013 | No | ||
11 | FANCC | 2060022 | 1373 | 0.766 | 0.1072 | No | ||
12 | SYNGR4 | 6520450 | 1416 | 0.749 | 0.1142 | No | ||
13 | POLD1 | 4830026 | 1667 | 0.641 | 0.1086 | No | ||
14 | PHF5A | 2690519 | 1760 | 0.607 | 0.1112 | No | ||
15 | RANBP1 | 430215 1090180 | 2036 | 0.519 | 0.1027 | No | ||
16 | PRPS1 | 6350129 | 2061 | 0.513 | 0.1078 | No | ||
17 | RPS6KA5 | 2120563 7040546 | 2150 | 0.485 | 0.1091 | No | ||
18 | HIST1H2BK | 6130433 | 2192 | 0.474 | 0.1127 | No | ||
19 | SFRS7 | 2760408 | 2235 | 0.461 | 0.1162 | No | ||
20 | MAZ | 3360121 6940750 | 2365 | 0.423 | 0.1144 | No | ||
21 | HIST1H4A | 1940600 | 2389 | 0.416 | 0.1184 | No | ||
22 | POLR2A | 5220647 | 2468 | 0.395 | 0.1190 | No | ||
23 | SUMO1 | 1990364 2760338 6380195 | 2474 | 0.393 | 0.1237 | No | ||
24 | RPS20 | 1740092 | 2527 | 0.381 | 0.1256 | No | ||
25 | HCN3 | 3940438 6840750 | 2541 | 0.377 | 0.1295 | No | ||
26 | FKBP5 | 2190048 | 2581 | 0.368 | 0.1320 | No | ||
27 | TBX6 | 4730139 6840647 | 2683 | 0.346 | 0.1308 | No | ||
28 | TRIM39 | 6550441 | 2951 | 0.297 | 0.1200 | No | ||
29 | H2AFV | 2030577 5220129 | 3051 | 0.280 | 0.1182 | No | ||
30 | ARID4A | 520156 1050707 | 3092 | 0.274 | 0.1194 | No | ||
31 | SEMA6A | 2690138 3060021 | 3366 | 0.230 | 0.1075 | No | ||
32 | FHOD1 | 2680279 | 3605 | 0.199 | 0.0970 | No | ||
33 | NCL | 2360463 4540279 | 3682 | 0.191 | 0.0953 | No | ||
34 | MXD3 | 6220014 | 3859 | 0.174 | 0.0879 | No | ||
35 | GPRC5B | 2760114 | 3924 | 0.168 | 0.0865 | No | ||
36 | CORT | 360008 2340092 | 4478 | 0.124 | 0.0581 | No | ||
37 | ING3 | 110438 2060390 | 4523 | 0.121 | 0.0573 | No | ||
38 | CDC6 | 4570296 5360600 | 4536 | 0.120 | 0.0581 | No | ||
39 | CCNT1 | 2450563 5390184 | 4547 | 0.120 | 0.0591 | No | ||
40 | HNRPR | 2320440 2900601 4610008 | 5017 | 0.094 | 0.0348 | No | ||
41 | HS6ST3 | 5910138 | 5144 | 0.089 | 0.0291 | No | ||
42 | FBXO5 | 2630551 | 5159 | 0.088 | 0.0294 | No | ||
43 | GMNN | 2630148 | 5396 | 0.078 | 0.0176 | No | ||
44 | PHF15 | 6550066 6860673 | 5863 | 0.062 | -0.0068 | No | ||
45 | TOPBP1 | 6020333 | 6541 | 0.044 | -0.0430 | No | ||
46 | NRK | 4590609 | 6834 | 0.038 | -0.0583 | No | ||
47 | STK35 | 2360121 | 6835 | 0.038 | -0.0578 | No | ||
48 | GRIA4 | 2640131 | 6933 | 0.037 | -0.0626 | No | ||
49 | SLC9A7 | 5360301 | 7472 | 0.026 | -0.0914 | No | ||
50 | TYRO3 | 3130193 | 7525 | 0.026 | -0.0939 | No | ||
51 | HNRPD | 4120021 | 7947 | 0.019 | -0.1165 | No | ||
52 | NELL2 | 2340725 4280301 5420008 | 8279 | 0.014 | -0.1343 | No | ||
53 | EPHB1 | 4610056 | 8294 | 0.014 | -0.1348 | No | ||
54 | KCNS2 | 2510093 6450672 | 8501 | 0.010 | -0.1459 | No | ||
55 | POLE2 | 6110041 | 8612 | 0.009 | -0.1517 | No | ||
56 | NR6A1 | 4010347 | 8616 | 0.009 | -0.1518 | No | ||
57 | ILF3 | 940722 3190647 6520110 | 8663 | 0.008 | -0.1542 | No | ||
58 | IPO7 | 2190746 | 8681 | 0.008 | -0.1550 | No | ||
59 | PLAGL1 | 3190082 6200193 | 8727 | 0.007 | -0.1573 | No | ||
60 | ZBTB4 | 6450441 | 9073 | 0.002 | -0.1760 | No | ||
61 | PEG3 | 3710020 | 9099 | 0.002 | -0.1773 | No | ||
62 | CASP8AP2 | 5910593 | 9128 | 0.002 | -0.1788 | No | ||
63 | MCM7 | 3290292 5220056 | 9312 | -0.001 | -0.1887 | No | ||
64 | DNAJC9 | 6130019 | 9348 | -0.001 | -0.1906 | No | ||
65 | ARHGAP6 | 2060121 | 9812 | -0.008 | -0.2156 | No | ||
66 | MYH10 | 2640673 | 9871 | -0.008 | -0.2186 | No | ||
67 | PODN | 3710068 | 9972 | -0.010 | -0.2239 | No | ||
68 | GABRB3 | 4150164 | 10569 | -0.019 | -0.2560 | No | ||
69 | PAX6 | 1190025 | 10695 | -0.021 | -0.2625 | No | ||
70 | ACBD6 | 4200446 | 10930 | -0.024 | -0.2748 | No | ||
71 | MCM8 | 6130743 | 11125 | -0.027 | -0.2850 | No | ||
72 | HOXC10 | 5360170 | 11438 | -0.033 | -0.3015 | No | ||
73 | HNRPA2B1 | 1240619 6200161 6200494 6980408 | 11467 | -0.033 | -0.3026 | No | ||
74 | YBX2 | 3520441 | 11472 | -0.033 | -0.3024 | No | ||
75 | GLRA3 | 2570500 | 11491 | -0.034 | -0.3030 | No | ||
76 | SLITRK4 | 5910022 | 11841 | -0.041 | -0.3214 | No | ||
77 | POU4F1 | 2260315 | 11989 | -0.043 | -0.3288 | No | ||
78 | RET | 3850746 | 12013 | -0.044 | -0.3295 | No | ||
79 | E2F7 | 4200056 | 12149 | -0.047 | -0.3362 | No | ||
80 | ASXL2 | 130670 | 12176 | -0.048 | -0.3370 | No | ||
81 | SP3 | 3840338 | 12229 | -0.049 | -0.3393 | No | ||
82 | CLSPN | 2190239 2630687 5550632 | 12305 | -0.051 | -0.3427 | No | ||
83 | PRPF4B | 940181 2570300 | 12694 | -0.061 | -0.3629 | No | ||
84 | FMO4 | 360735 | 12707 | -0.061 | -0.3628 | No | ||
85 | DMD | 1740041 3990332 | 12741 | -0.062 | -0.3638 | No | ||
86 | SMAD6 | 870504 | 13179 | -0.076 | -0.3866 | No | ||
87 | PAQR4 | 730736 | 13188 | -0.076 | -0.3861 | No | ||
88 | STAG1 | 1190300 1400722 4590100 | 13358 | -0.083 | -0.3942 | No | ||
89 | PCSK1 | 2350148 | 13404 | -0.085 | -0.3956 | No | ||
90 | MAP3K7 | 6040068 | 13743 | -0.099 | -0.4126 | No | ||
91 | MAPT | 360706 1230706 | 13772 | -0.100 | -0.4129 | No | ||
92 | HNRPUL1 | 2120008 4920408 5570180 6370609 6770403 | 14128 | -0.121 | -0.4306 | No | ||
93 | RQCD1 | 1850139 | 14282 | -0.131 | -0.4373 | No | ||
94 | SNRPD1 | 4480162 | 14410 | -0.140 | -0.4424 | No | ||
95 | FANCG | 4010471 | 14462 | -0.144 | -0.4434 | No | ||
96 | PRKDC | 1400072 4230541 | 14641 | -0.161 | -0.4511 | No | ||
97 | AP1S1 | 2030471 4570520 6900603 | 14727 | -0.167 | -0.4536 | No | ||
98 | ADAMTS2 | 2650025 6370133 6840670 | 14747 | -0.169 | -0.4525 | No | ||
99 | KCNA6 | 450291 1400086 1660291 2470576 | 14806 | -0.174 | -0.4535 | No | ||
100 | SYNCRIP | 1690195 3140113 4670279 | 14861 | -0.182 | -0.4541 | No | ||
101 | E2F3 | 50162 460180 | 15049 | -0.203 | -0.4618 | No | ||
102 | EED | 2320373 | 15059 | -0.204 | -0.4597 | No | ||
103 | GATA1 | 6400068 | 15089 | -0.208 | -0.4587 | No | ||
104 | USP37 | 2470433 | 15128 | -0.212 | -0.4581 | No | ||
105 | EFNA5 | 460707 2190519 | 15207 | -0.225 | -0.4596 | No | ||
106 | MYC | 380541 4670170 | 15358 | -0.246 | -0.4646 | No | ||
107 | HIRA | 4480609 5270167 | 15399 | -0.252 | -0.4637 | No | ||
108 | EZH2 | 6130605 6380524 | 15457 | -0.264 | -0.4635 | No | ||
109 | HIST1H2AH | 3710333 | 15665 | -0.303 | -0.4709 | No | ||
110 | ATAD2 | 870242 2260687 | 15795 | -0.334 | -0.4738 | No | ||
111 | BRMS1L | 6110609 | 15850 | -0.345 | -0.4724 | No | ||
112 | MCM2 | 5050139 | 16009 | -0.385 | -0.4762 | No | ||
113 | MCM6 | 60092 540181 6510110 | 16029 | -0.390 | -0.4724 | No | ||
114 | NOLC1 | 2350195 | 16397 | -0.494 | -0.4861 | Yes | ||
115 | MRPL40 | 2370215 | 16472 | -0.515 | -0.4837 | Yes | ||
116 | AK2 | 4590458 4760195 6110097 | 16550 | -0.545 | -0.4811 | Yes | ||
117 | MCM4 | 2760673 5420711 | 16712 | -0.605 | -0.4823 | Yes | ||
118 | PIM1 | 630047 | 16761 | -0.621 | -0.4772 | Yes | ||
119 | SLCO3A1 | 1050408 2370156 6110072 | 16768 | -0.624 | -0.4698 | Yes | ||
120 | UNG | 3130110 6100364 | 16876 | -0.670 | -0.4673 | Yes | ||
121 | MCM3 | 5570068 | 16965 | -0.703 | -0.4633 | Yes | ||
122 | ACO2 | 4230600 | 17123 | -0.778 | -0.4622 | Yes | ||
123 | MSH2 | 6180273 | 17144 | -0.787 | -0.4535 | Yes | ||
124 | CDCA7 | 3060097 | 17155 | -0.793 | -0.4442 | Yes | ||
125 | PCNA | 940754 | 17203 | -0.821 | -0.4365 | Yes | ||
126 | H2AFZ | 1470168 | 17329 | -0.879 | -0.4324 | Yes | ||
127 | POLE4 | 6860097 | 17428 | -0.944 | -0.4259 | Yes | ||
128 | FANCD2 | 1850280 6840348 | 17580 | -1.003 | -0.4217 | Yes | ||
129 | NUP62 | 1240128 | 17593 | -1.009 | -0.4098 | Yes | ||
130 | CDC5L | 3130446 3390025 6400204 | 17635 | -1.028 | -0.3992 | Yes | ||
131 | BRPF1 | 3170139 | 17641 | -1.030 | -0.3867 | Yes | ||
132 | PTMA | 5570148 | 17683 | -1.061 | -0.3757 | Yes | ||
133 | POLD3 | 6400278 | 17691 | -1.066 | -0.3629 | Yes | ||
134 | RBL1 | 3130372 | 17703 | -1.074 | -0.3501 | Yes | ||
135 | CDC25A | 3800184 | 17772 | -1.122 | -0.3399 | Yes | ||
136 | PHC1 | 520195 | 17845 | -1.184 | -0.3291 | Yes | ||
137 | HTF9C | 3190048 4120132 | 17852 | -1.188 | -0.3147 | Yes | ||
138 | IL4I1 | 3190161 | 17853 | -1.188 | -0.2999 | Yes | ||
139 | NASP | 2260139 2940369 5130707 | 17862 | -1.193 | -0.2855 | Yes | ||
140 | ALDH6A1 | 1770746 | 17943 | -1.249 | -0.2743 | Yes | ||
141 | SFRS1 | 2360440 | 18010 | -1.309 | -0.2617 | Yes | ||
142 | STMN1 | 1990717 | 18068 | -1.364 | -0.2478 | Yes | ||
143 | ZCCHC8 | 2260332 2350487 | 18085 | -1.377 | -0.2316 | Yes | ||
144 | EIF4A1 | 1990341 2810300 | 18104 | -1.391 | -0.2153 | Yes | ||
145 | E2F1 | 5360093 | 18222 | -1.543 | -0.2025 | Yes | ||
146 | CBX3 | 1780592 3940008 | 18249 | -1.572 | -0.1843 | Yes | ||
147 | AP4M1 | 70609 3440128 | 18291 | -1.638 | -0.1662 | Yes | ||
148 | GSPT1 | 5420050 | 18376 | -1.825 | -0.1481 | Yes | ||
149 | UGCGL1 | 4230072 | 18385 | -1.856 | -0.1255 | Yes | ||
150 | DCK | 6900411 | 18435 | -1.963 | -0.1038 | Yes | ||
151 | PPM1D | 1690193 | 18460 | -2.052 | -0.0796 | Yes | ||
152 | MAPK6 | 6760520 | 18478 | -2.130 | -0.0540 | Yes | ||
153 | SOAT1 | 1190019 | 18490 | -2.177 | -0.0276 | Yes | ||
154 | TMPO | 4050494 | 18577 | -2.767 | 0.0021 | Yes |