Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #wtNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_wtNotch.cls#wtNotch_versus_absentNotch |
Upregulated in class | absentNotch |
GeneSet | V$ARNT_01 |
Enrichment Score (ES) | -0.50478256 |
Normalized Enrichment Score (NES) | -1.5178047 |
Nominal p-value | 0.0034722222 |
FDR q-value | 0.17004761 |
FWER p-Value | 0.837 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | LEF1 | 2470082 7100288 | 214 | 1.758 | 0.0079 | No | ||
2 | UBE1 | 4150139 7050463 | 304 | 1.584 | 0.0206 | No | ||
3 | CHD4 | 5420059 6130338 6380717 | 406 | 1.424 | 0.0309 | No | ||
4 | HOXB4 | 540131 | 566 | 1.246 | 0.0361 | No | ||
5 | VARS2 | 1410017 3800114 4210270 | 644 | 1.182 | 0.0450 | No | ||
6 | HMGN2 | 3140091 | 762 | 1.096 | 0.0508 | No | ||
7 | ZFYVE26 | 6860152 | 810 | 1.060 | 0.0600 | No | ||
8 | OPRS1 | 6130128 6290717 | 845 | 1.032 | 0.0696 | No | ||
9 | TEF | 1050050 3120397 4060487 | 879 | 1.008 | 0.0790 | No | ||
10 | RTN4 | 50725 630647 870097 870184 | 886 | 1.005 | 0.0898 | No | ||
11 | UBXD1 | 5130079 5390167 | 975 | 0.971 | 0.0958 | No | ||
12 | PLCG2 | 5720008 | 1101 | 0.899 | 0.0990 | No | ||
13 | VPS16 | 430064 3390041 6860301 | 1113 | 0.893 | 0.1083 | No | ||
14 | ZCCHC7 | 6510592 | 1300 | 0.793 | 0.1070 | No | ||
15 | IL15RA | 2570270 3190711 6100091 6100270 | 1307 | 0.790 | 0.1154 | No | ||
16 | CCAR1 | 3190092 | 1344 | 0.777 | 0.1221 | No | ||
17 | PPP1R1B | 5290403 5550324 | 1531 | 0.698 | 0.1197 | No | ||
18 | AP1GBP1 | 2510372 | 1679 | 0.638 | 0.1188 | No | ||
19 | PRPS1 | 6350129 | 2061 | 0.513 | 0.1039 | No | ||
20 | TIMM9 | 2450484 | 2075 | 0.508 | 0.1088 | No | ||
21 | NDUFA7 | 5900722 | 2220 | 0.467 | 0.1061 | No | ||
22 | B3GALT6 | 50195 | 2241 | 0.460 | 0.1102 | No | ||
23 | SMYD4 | 2640403 | 2392 | 0.415 | 0.1066 | No | ||
24 | GTF2H1 | 2570746 2650148 | 2403 | 0.412 | 0.1106 | No | ||
25 | MYST3 | 5270500 | 2720 | 0.339 | 0.0973 | No | ||
26 | SNX2 | 2470068 3360364 6510064 | 2944 | 0.298 | 0.0885 | No | ||
27 | NR5A1 | 70707 | 3063 | 0.278 | 0.0852 | No | ||
28 | CRY2 | 6290722 | 3273 | 0.243 | 0.0765 | No | ||
29 | ISGF3G | 3190131 7100142 | 3293 | 0.240 | 0.0781 | No | ||
30 | ATP6V1A | 6590242 | 3325 | 0.234 | 0.0791 | No | ||
31 | SLC35A5 | 2970670 4480546 | 3358 | 0.231 | 0.0799 | No | ||
32 | SCYL1 | 5050717 | 3364 | 0.230 | 0.0822 | No | ||
33 | RCL1 | 1980408 2680008 3800176 | 3373 | 0.229 | 0.0843 | No | ||
34 | DUSP7 | 2940309 | 3538 | 0.207 | 0.0777 | No | ||
35 | HNRPA1 | 4670398 5050687 | 3753 | 0.184 | 0.0681 | No | ||
36 | COPS7A | 3940458 7000022 | 3769 | 0.182 | 0.0693 | No | ||
37 | ARMET | 5130670 | 3816 | 0.178 | 0.0688 | No | ||
38 | LZTS2 | 2260440 | 3879 | 0.172 | 0.0673 | No | ||
39 | GATA5 | 430465 | 3902 | 0.169 | 0.0680 | No | ||
40 | ESRRA | 6550242 | 3953 | 0.165 | 0.0671 | No | ||
41 | HSPD1 | 60097 2030451 | 3998 | 0.161 | 0.0665 | No | ||
42 | PPRC1 | 1740441 | 4000 | 0.161 | 0.0683 | No | ||
43 | EGLN2 | 540086 | 4060 | 0.156 | 0.0668 | No | ||
44 | ARRDC3 | 4610390 | 4117 | 0.150 | 0.0654 | No | ||
45 | TESK2 | 6520524 | 4155 | 0.147 | 0.0651 | No | ||
46 | NEUROD1 | 3060619 | 4179 | 0.145 | 0.0654 | No | ||
47 | QTRT1 | 1340162 | 4267 | 0.139 | 0.0622 | No | ||
48 | NEUROG2 | 5420278 | 4472 | 0.124 | 0.0526 | No | ||
49 | HOXB7 | 4540706 4610358 | 4493 | 0.123 | 0.0528 | No | ||
50 | RBBP6 | 2320129 | 4707 | 0.111 | 0.0425 | No | ||
51 | NRIP3 | 1340372 | 4783 | 0.106 | 0.0396 | No | ||
52 | CNNM1 | 2190433 | 5143 | 0.089 | 0.0212 | No | ||
53 | FGF14 | 2630390 3520075 6770048 | 5366 | 0.079 | 0.0100 | No | ||
54 | RNF128 | 1230300 5670273 | 5449 | 0.077 | 0.0064 | No | ||
55 | DVL2 | 6110162 | 5617 | 0.070 | -0.0019 | No | ||
56 | TAC1 | 7000195 380706 | 5645 | 0.069 | -0.0026 | No | ||
57 | BMP4 | 380113 | 5651 | 0.069 | -0.0021 | No | ||
58 | BDNF | 2940128 3520368 | 5794 | 0.064 | -0.0091 | No | ||
59 | PPP1R3C | 2640170 | 5849 | 0.062 | -0.0113 | No | ||
60 | SYT6 | 2510280 3850128 4540064 | 5957 | 0.059 | -0.0165 | No | ||
61 | MTUS1 | 780348 4920609 | 6159 | 0.054 | -0.0268 | No | ||
62 | HOXA7 | 5910152 | 6346 | 0.049 | -0.0363 | No | ||
63 | PHC3 | 4920332 | 6367 | 0.048 | -0.0369 | No | ||
64 | ELAVL3 | 2850014 | 6851 | 0.038 | -0.0626 | No | ||
65 | DNAJB9 | 460114 | 7648 | 0.024 | -0.1055 | No | ||
66 | BHLHB3 | 3450438 | 7842 | 0.020 | -0.1158 | No | ||
67 | UBE2B | 4780497 | 8000 | 0.018 | -0.1241 | No | ||
68 | AMPD2 | 630093 1170070 | 8545 | 0.010 | -0.1535 | No | ||
69 | BMP2K | 60541 5570504 | 8609 | 0.009 | -0.1568 | No | ||
70 | ILF3 | 940722 3190647 6520110 | 8663 | 0.008 | -0.1596 | No | ||
71 | ODC1 | 5670168 | 8725 | 0.007 | -0.1628 | No | ||
72 | EIF3S10 | 1190079 3840176 | 8954 | 0.004 | -0.1751 | No | ||
73 | SLCO1C1 | 5390494 | 9014 | 0.003 | -0.1783 | No | ||
74 | TRPM7 | 2510408 | 9040 | 0.003 | -0.1796 | No | ||
75 | ETV4 | 2450605 | 9060 | 0.003 | -0.1806 | No | ||
76 | HOXD10 | 6100039 | 9137 | 0.002 | -0.1847 | No | ||
77 | HOXB5 | 2900538 | 9344 | -0.001 | -0.1959 | No | ||
78 | AP1S2 | 780279 4280707 | 9455 | -0.003 | -0.2018 | No | ||
79 | CELSR3 | 5270731 7100082 | 9524 | -0.004 | -0.2054 | No | ||
80 | XPO1 | 540707 | 9544 | -0.004 | -0.2064 | No | ||
81 | AKAP10 | 2630504 5910577 | 9553 | -0.004 | -0.2068 | No | ||
82 | SLC38A5 | 540093 | 9607 | -0.005 | -0.2096 | No | ||
83 | DNMT3A | 4050068 4810717 | 9722 | -0.006 | -0.2157 | No | ||
84 | ZBTB10 | 4200132 | 9799 | -0.007 | -0.2198 | No | ||
85 | PCDHA10 | 3830725 | 9989 | -0.010 | -0.2299 | No | ||
86 | CBX5 | 3830072 6290167 | 10003 | -0.010 | -0.2305 | No | ||
87 | SNX5 | 1570021 6860609 | 10400 | -0.016 | -0.2518 | No | ||
88 | TBC1D5 | 5360619 6130603 | 10448 | -0.017 | -0.2542 | No | ||
89 | ABCA1 | 6290156 | 10521 | -0.018 | -0.2579 | No | ||
90 | PAX6 | 1190025 | 10695 | -0.021 | -0.2670 | No | ||
91 | HOXA11 | 6980133 | 10835 | -0.023 | -0.2743 | No | ||
92 | JAG1 | 3440390 | 10896 | -0.024 | -0.2773 | No | ||
93 | NKX2-2 | 4150731 | 11094 | -0.027 | -0.2877 | No | ||
94 | TBC1D15 | 870673 | 11200 | -0.029 | -0.2931 | No | ||
95 | PICALM | 1940280 | 11250 | -0.030 | -0.2954 | No | ||
96 | ADAMTS19 | 2680739 | 11280 | -0.030 | -0.2966 | No | ||
97 | POGK | 5290315 | 11670 | -0.037 | -0.3173 | No | ||
98 | FLT3 | 2640487 | 12105 | -0.046 | -0.3403 | No | ||
99 | NPM1 | 4730427 | 12115 | -0.046 | -0.3403 | No | ||
100 | FOXD3 | 6550156 | 12382 | -0.053 | -0.3541 | No | ||
101 | SYT3 | 6380017 | 12429 | -0.054 | -0.3560 | No | ||
102 | HOXA1 | 1190524 5420142 | 12476 | -0.055 | -0.3579 | No | ||
103 | VLDLR | 870722 3060047 5340452 6550131 | 12484 | -0.055 | -0.3577 | No | ||
104 | TCEAL1 | 870577 | 12651 | -0.059 | -0.3660 | No | ||
105 | SLC39A11 | 5860687 | 12914 | -0.067 | -0.3795 | No | ||
106 | FOXF2 | 1240091 | 13007 | -0.070 | -0.3837 | No | ||
107 | MBNL1 | 2640762 7100048 | 13161 | -0.075 | -0.3912 | No | ||
108 | ETV1 | 70735 2940603 5080463 | 13625 | -0.094 | -0.4152 | No | ||
109 | DSCAM | 1780050 2450731 2810438 | 13725 | -0.098 | -0.4195 | No | ||
110 | TGFB2 | 4920292 | 13877 | -0.105 | -0.4265 | No | ||
111 | NPTX1 | 3710736 | 13962 | -0.111 | -0.4299 | No | ||
112 | NEUROD2 | 5290097 | 14163 | -0.123 | -0.4393 | No | ||
113 | SYNCRIP | 1690195 3140113 4670279 | 14861 | -0.182 | -0.4751 | No | ||
114 | PDGFB | 3060440 6370008 | 15042 | -0.203 | -0.4826 | No | ||
115 | SHMT1 | 5900132 | 15082 | -0.207 | -0.4825 | No | ||
116 | SNAP25 | 360520 | 15235 | -0.228 | -0.4882 | No | ||
117 | SIRT1 | 1190731 | 15314 | -0.239 | -0.4898 | No | ||
118 | JPH1 | 610739 | 15320 | -0.240 | -0.4874 | No | ||
119 | HIRA | 4480609 5270167 | 15399 | -0.252 | -0.4888 | No | ||
120 | LTBR | 2450341 | 15541 | -0.278 | -0.4934 | No | ||
121 | PABPN1 | 460519 | 15572 | -0.285 | -0.4918 | No | ||
122 | MNT | 4920575 | 15616 | -0.295 | -0.4909 | No | ||
123 | RAB3IL1 | 380685 5420176 | 15752 | -0.323 | -0.4946 | No | ||
124 | ARMCX3 | 3290309 | 15873 | -0.349 | -0.4973 | No | ||
125 | PAK2 | 360438 7050068 | 15904 | -0.358 | -0.4949 | No | ||
126 | EPC1 | 1570050 5290095 6900193 | 15993 | -0.380 | -0.4955 | No | ||
127 | GATA4 | 1410215 2690609 | 16110 | -0.409 | -0.4972 | No | ||
128 | TCERG1 | 2350551 4540397 5220746 | 16250 | -0.445 | -0.4999 | Yes | ||
129 | COMMD8 | 5890358 | 16277 | -0.455 | -0.4962 | Yes | ||
130 | PSME3 | 2810537 | 16351 | -0.483 | -0.4948 | Yes | ||
131 | BRD2 | 1450300 5340484 6100605 | 16425 | -0.502 | -0.4932 | Yes | ||
132 | AATF | 5220575 | 16436 | -0.505 | -0.4882 | Yes | ||
133 | MRPL40 | 2370215 | 16472 | -0.515 | -0.4844 | Yes | ||
134 | RPA1 | 360452 | 16606 | -0.563 | -0.4853 | Yes | ||
135 | EIF4E | 1580403 70133 6380215 | 16676 | -0.587 | -0.4826 | Yes | ||
136 | UBXD3 | 5050193 | 16804 | -0.638 | -0.4824 | Yes | ||
137 | ATF7IP | 2690176 6770021 | 16813 | -0.642 | -0.4757 | Yes | ||
138 | RPL13A | 2680519 5700142 | 16819 | -0.644 | -0.4688 | Yes | ||
139 | CLN3 | 780368 | 16896 | -0.678 | -0.4654 | Yes | ||
140 | HPS3 | 6650348 | 16981 | -0.711 | -0.4621 | Yes | ||
141 | DCTN4 | 3390010 5550170 | 16989 | -0.716 | -0.4546 | Yes | ||
142 | MAP2K6 | 1230056 2940204 | 17105 | -0.770 | -0.4523 | Yes | ||
143 | ATP6V1C1 | 2690324 5220528 | 17305 | -0.865 | -0.4535 | Yes | ||
144 | CD164 | 3830594 | 17441 | -0.949 | -0.4503 | Yes | ||
145 | UTX | 2900017 6770452 | 17446 | -0.954 | -0.4399 | Yes | ||
146 | PPAT | 1980019 | 17474 | -0.966 | -0.4307 | Yes | ||
147 | CBARA1 | 360471 | 17489 | -0.973 | -0.4206 | Yes | ||
148 | CSRP2BP | 4570717 5550333 | 17534 | -0.996 | -0.4120 | Yes | ||
149 | NIT1 | 1230338 3940671 | 17552 | -0.999 | -0.4019 | Yes | ||
150 | FXYD6 | 3870164 | 17615 | -1.020 | -0.3939 | Yes | ||
151 | PTMA | 5570148 | 17683 | -1.061 | -0.3858 | Yes | ||
152 | PAICS | 610142 | 17735 | -1.095 | -0.3764 | Yes | ||
153 | DDX3X | 2190020 | 17759 | -1.115 | -0.3653 | Yes | ||
154 | ARF6 | 3520026 | 17773 | -1.123 | -0.3536 | Yes | ||
155 | COMMD3 | 2510259 | 17788 | -1.142 | -0.3417 | Yes | ||
156 | ALDH6A1 | 1770746 | 17943 | -1.249 | -0.3362 | Yes | ||
157 | EIF2C2 | 770451 | 17967 | -1.267 | -0.3234 | Yes | ||
158 | RNF44 | 5910692 | 17985 | -1.278 | -0.3102 | Yes | ||
159 | STMN1 | 1990717 | 18068 | -1.364 | -0.2995 | Yes | ||
160 | AKAP12 | 1450739 | 18094 | -1.383 | -0.2855 | Yes | ||
161 | ATP6V0B | 2810112 | 18143 | -1.444 | -0.2721 | Yes | ||
162 | BCL11B | 2680673 | 18154 | -1.464 | -0.2564 | Yes | ||
163 | UBE4B | 780008 3610154 | 18163 | -1.473 | -0.2405 | Yes | ||
164 | BOK | 1170373 5860446 | 18242 | -1.565 | -0.2274 | Yes | ||
165 | MTCH2 | 3780603 6620215 | 18248 | -1.571 | -0.2103 | Yes | ||
166 | RHEBL1 | 2810576 | 18266 | -1.591 | -0.1936 | Yes | ||
167 | NUDC | 4780025 | 18392 | -1.882 | -0.1795 | Yes | ||
168 | LAMP1 | 2470524 | 18413 | -1.920 | -0.1593 | Yes | ||
169 | STX6 | 4850750 6770278 | 18434 | -1.963 | -0.1386 | Yes | ||
170 | SNX8 | 3450315 | 18445 | -2.000 | -0.1170 | Yes | ||
171 | EIF4B | 5390563 5270577 | 18473 | -2.090 | -0.0953 | Yes | ||
172 | KBTBD2 | 2320014 | 18488 | -2.165 | -0.0721 | Yes | ||
173 | IFRD2 | 4150110 | 18502 | -2.213 | -0.0482 | Yes | ||
174 | PER1 | 3290315 | 18540 | -2.373 | -0.0240 | Yes | ||
175 | NR1D1 | 2360471 770746 6590204 | 18562 | -2.528 | 0.0029 | Yes |