Details for gene set MANALO_HYPOXIA

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #wtNotch_versus_absentNotch
Phenotype	phenotype_absentNotch_versus_wtNotch.cls#wtNotch_versus_absentNotch
Upregulated in class	absentNotch
GeneSet	MANALO_HYPOXIA_DN
Enrichment Score (ES)	-0.6007057
Normalized Enrichment Score (NES)	-1.63867
Nominal p-value	0.0
FDR q-value	0.18294075
FWER p-Value	0.936

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CCNF	6370288	249	1.700	0.0235	No
2	RRM2	6350059 6940162	318	1.562	0.0538	No
3	CDC7	4060546 4850041	757	1.100	0.0541	No
4	SNRPA1	1050735 6110131	866	1.019	0.0704	No
5	POLR3K	1400577 5290500	1551	0.691	0.0485	No
6	CTPS	70451 1740132	1562	0.689	0.0630	No
7	PRPS1	6350129	2061	0.513	0.0473	No
8	GTPBP4	6840332	2166	0.482	0.0521	No
9	MAZ	3360121 6940750	2365	0.423	0.0506	No
10	PA2G4	2030463	2615	0.362	0.0451	No
11	BARD1	3170348	2804	0.323	0.0420	No
12	DHX35	1230440	2811	0.322	0.0486	No
13	MCM5	2680647	2931	0.300	0.0487	No
14	MLLT10	1410288 3290142	3425	0.222	0.0270	No
15	NEK4	430731 2060010 7000333	3663	0.193	0.0184	No
16	DHFR	6350315	3891	0.170	0.0099	No
17	CDC6	4570296 5360600	4536	0.120	-0.0223	No
18	MCM10	4920632	4918	0.099	-0.0406	No
19	MAD2L1	4480725	5119	0.090	-0.0495	No
20	PSMD11	2340538 6510053	5215	0.086	-0.0527	No
21	TFAM	3190164 6840195	5243	0.085	-0.0524	No
22	MFN2	2260195 6100164	5464	0.076	-0.0626	No
23	USP1	2760541 5690438 6220673	7021	0.035	-0.1457	No
24	HNRPU	6520736	7146	0.032	-0.1517	No
25	HNRPD	4120021	7947	0.019	-0.1944	No
26	POLE2	6110041	8612	0.009	-0.2300	No
27	ILF3	940722 3190647 6520110	8663	0.008	-0.2326	No
28	PPARD	110131	8951	0.004	-0.2480	No
29	DNA2L	6660368	11340	-0.031	-0.3760	No
30	RRS1	4560551	11827	-0.040	-0.4014	No
31	UMPS	2340541 4730438	12104	-0.046	-0.4153	No
32	BRCA1	4780669	13331	-0.081	-0.4796	No
33	TRIP13	6860341	13514	-0.089	-0.4875	No
34	UCHL5	540139 1690053	13797	-0.101	-0.5005	No
35	SNRPD1	4480162	14410	-0.140	-0.5304	No
36	SNAPC5	1580215	14565	-0.154	-0.5354	No
37	RPL39	2370446	15452	-0.262	-0.5775	No
38	POLD2	6400148	15614	-0.294	-0.5798	No
39	RRM1	4150433	16003	-0.383	-0.5924	Yes
40	MCM2	5050139	16009	-0.385	-0.5843	Yes
41	MCM6	60092 540181 6510110	16029	-0.390	-0.5768	Yes
42	BOP1	4810040	16111	-0.409	-0.5723	Yes
43	CHAF1A	6040647	16230	-0.440	-0.5691	Yes
44	DDX11	6590671	16267	-0.453	-0.5612	Yes
45	DDX21	6100446	16350	-0.483	-0.5552	Yes
46	PSME3	2810537	16351	-0.483	-0.5447	Yes
47	CCNE2	3120537	16390	-0.493	-0.5360	Yes
48	NOLC1	2350195	16397	-0.494	-0.5256	Yes
49	MRPL40	2370215	16472	-0.515	-0.5184	Yes
50	RB1	5900338	16521	-0.534	-0.5094	Yes
51	PSME4	380348 1770131	16663	-0.583	-0.5043	Yes
52	PRC1	870092 5890204	16671	-0.586	-0.4920	Yes
53	MCM4	2760673 5420711	16712	-0.605	-0.4810	Yes
54	SNRPD3	2970050	16721	-0.608	-0.4682	Yes
55	MCM3	5570068	16965	-0.703	-0.4660	Yes
56	RPP30	1980221	17161	-0.795	-0.4592	Yes
57	ZWINT	6940670	17231	-0.833	-0.4449	Yes
58	MRPL46	360736	17250	-0.841	-0.4275	Yes
59	MRPS12	4210707 6110341	17402	-0.923	-0.4156	Yes
60	RFC5	3800452 6020091	17442	-0.950	-0.3971	Yes
61	POLG	780465	17498	-0.979	-0.3788	Yes
62	SFRS2	50707 380593	17526	-0.992	-0.3587	Yes
63	USP39	1090242 3520435 4760736	17603	-1.015	-0.3407	Yes
64	UBE2S	1850110	17793	-1.145	-0.3260	Yes
65	SKP2	360711 380093 4810368	18191	-1.508	-0.3147	Yes
66	RFC3	1980600	18206	-1.522	-0.2823	Yes
67	ORC6L	2260592	18279	-1.617	-0.2511	Yes
68	ATIC	4010593 6380463	18292	-1.642	-0.2161	Yes
69	NOL5A	5570139	18524	-2.285	-0.1789	Yes
70	CCNE1	110064	18532	-2.311	-0.1290	Yes
71	DDX18	6980619	18586	-2.998	-0.0667	Yes
72	HNRPDL	1050102 1090181 5360471	18599	-3.143	0.0009	Yes