Table: Gene sets enriched in phenotype wtNotch (4 samples) [plain text format]

	GS follow link to MSigDB	GS DETAILS	SIZE	ES	NES	NOM p-val	FDR q-val	FWER p-val	RANK AT MAX	LEADING EDGE
1	REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT	Details ...	16	0.90	1.88	0.000	0.008	0.012	10	tags=13%, list=0%, signal=12%
2	HUMANCYC_SUPERPATHWAY OF N-ACETYLNEURAMINATE DEGRADATION	Details ...	22	0.81	1.80	0.000	0.024	0.074	1850	tags=50%, list=10%, signal=55%
3	HUMANCYC_GLYCOLYSIS III	Details ...	21	0.80	1.79	0.002	0.021	0.096	1662	tags=43%, list=9%, signal=47%
4	HUMANCYC_GLYCOLYSIS I	Details ...	20	0.81	1.77	0.000	0.023	0.140	1662	tags=45%, list=9%, signal=49%
5	HUMANCYC_GLYCOLYSIS V	Details ...	18	0.80	1.73	0.004	0.043	0.287	1662	tags=44%, list=9%, signal=49%
6	HUMANCYC_SUPERPATHWAY OF GLYCOLYSIS AND ENTNER-DOUDOROFF	Details ...	22	0.73	1.64	0.008	0.171	0.815	1662	tags=45%, list=9%, signal=50%
7	INOH_CANONICAL NOTCH SIGNALING PATHWAY	Details ...	26	0.69	1.62	0.006	0.177	0.870	1091	tags=23%, list=6%, signal=24%
8	INOH_MAMMALIAN NOTCH SIGNALING PATHWAY	Details ...	22	0.73	1.62	0.006	0.158	0.875	1091	tags=32%, list=6%, signal=34%
9	INOH_NOTCH SECRETORY PATHWAY (MAMMAL)	Details ...	22	0.73	1.60	0.019	0.206	0.950	1091	tags=32%, list=6%, signal=34%
10	INOH_NOTCH SECRETORY PATHWAY	Details ...	26	0.69	1.59	0.012	0.189	0.952	1091	tags=23%, list=6%, signal=24%
11	HUMANCYC_GLUCONEOGENESIS	Details ...	17	0.75	1.58	0.010	0.196	0.971	1150	tags=29%, list=6%, signal=31%
12	HUMANCYC_SUPERPATHWAY OF GLYCOLYSIS, PYRUVATE DEHYDROGENASE, TCA, AND GLYOXYLATE BYPASS	Details ...	39	0.59	1.50	0.013	0.478	1.000	2488	tags=36%, list=13%, signal=41%
13	REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS	Details ...	18	0.70	1.48	0.032	0.544	1.000	1342	tags=28%, list=7%, signal=30%
14	REACTOME_GLUCONEOGENESIS	Details ...	11	0.76	1.46	0.047	0.602	1.000	2300	tags=55%, list=12%, signal=62%
15	INOH_GENE EXPRESSION OF SOCS1 BY STAT DIMER	Details ...	30	0.60	1.44	0.040	0.658	1.000	2509	tags=47%, list=13%, signal=54%
16	HUMANCYC_TRIACYLGLYCEROL BIOSYNTHESIS	Details ...	11	0.75	1.43	0.081	0.657	1.000	1942	tags=45%, list=10%, signal=51%
17	INOH_NEGATIVE FEEDBACK REGULATION OF JAK STAT PATHWAY BY (JAK DEGRADATION SIGNALING)	Details ...	30	0.60	1.42	0.044	0.650	1.000	2509	tags=47%, list=13%, signal=54%
18	NCI_VISUAL SIGNAL TRANSDUCTION: CONES	Details ...	18	0.66	1.42	0.068	0.630	1.000	141	tags=6%, list=1%, signal=6%
19	BIOCARTA_IL22 SOLUBLE RECEPTOR SIGNALING PATHWAY	Details ...	11	0.73	1.42	0.071	0.608	1.000	2171	tags=45%, list=12%, signal=51%
20	BIOCARTA_LCK AND FYN TYROSINE KINASES IN INITIATION OF TCR ACTIVATION	Details ...	10	0.75	1.42	0.062	0.589	1.000	2730	tags=70%, list=15%, signal=82%
21	REACTOME_PYRUVATE_METABOLISM_AND_TCA_CYCLE		17	0.65	1.40	0.074	0.616	1.000	2123	tags=41%, list=11%, signal=46%
22	REACTOME_METABOLISM_OF_CARBOHYDRATES		70	0.51	1.39	0.037	0.664	1.000	2493	tags=36%, list=13%, signal=41%
23	REACTOME_PURINE_SALVAGE_REACTIONS		10	0.73	1.37	0.095	0.701	1.000	1619	tags=40%, list=9%, signal=44%
24	REACTOME_GLUCOSE_REGULATION_OF_INSULIN_SECRETION		90	0.48	1.37	0.024	0.677	1.000	2709	tags=42%, list=15%, signal=49%
25	REACTOME_REGULATION_OF_INSULIN_SECRETION		101	0.47	1.36	0.021	0.707	1.000	2709	tags=41%, list=15%, signal=47%
26	NCI_SIGNALING EVENTS MEDIATED BY PTP1B		46	0.53	1.36	0.066	0.696	1.000	3010	tags=24%, list=16%, signal=28%
27	INOH_NEGATIVE FEEDBACK REGULATION OF JAK STAT PATHWAY BY (CYTOKINE RECEPTOR DEGRADATION SIGNALING)		26	0.58	1.36	0.085	0.672	1.000	2509	tags=50%, list=13%, signal=58%
28	REACTOME_STEROID_METABOLISM		36	0.54	1.35	0.077	0.681	1.000	1125	tags=22%, list=6%, signal=24%
29	REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES		64	0.50	1.35	0.053	0.665	1.000	1798	tags=20%, list=10%, signal=22%
30	INOH_GENE EXPRESSION OF SOCS3 BY STAT DIMER		26	0.58	1.34	0.089	0.652	1.000	2509	tags=50%, list=13%, signal=58%
31	NCI_PRESENILIN ACTION IN NOTCH AND WNT SIGNALING		40	0.52	1.31	0.076	0.785	1.000	1279	tags=18%, list=7%, signal=19%
32	NCI_IL27-MEDIATED SIGNALING EVENTS		26	0.56	1.30	0.105	0.788	1.000	2648	tags=38%, list=14%, signal=45%
33	HUMANCYC_SERINE-ISOCITRATE LYASE PATHWAY		16	0.63	1.30	0.137	0.800	1.000	1487	tags=31%, list=8%, signal=34%
34	REACTOME_CITRIC_ACID_CYCLE__TCA_CYCLE_		12	0.66	1.29	0.152	0.793	1.000	2123	tags=50%, list=11%, signal=56%
35	REACTOME_ACTIVATION_OF_APC_C_AND_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS		45	0.51	1.29	0.078	0.795	1.000	2633	tags=38%, list=14%, signal=44%
36	REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS		44	0.51	1.29	0.108	0.775	1.000	2633	tags=39%, list=14%, signal=45%
37	HUMANCYC_ENTNER-DOUDOROFF PATHWAY II (NON-PHOSPHORYLATIVE)		12	0.67	1.28	0.172	0.769	1.000	860	tags=25%, list=5%, signal=26%
38	INOH_JAK DEGRADATION SIGNALING		24	0.56	1.28	0.140	0.775	1.000	1403	tags=29%, list=8%, signal=32%
39	REACTOME_CHOLESTEROL_BIOSYNTHESIS		15	0.62	1.28	0.159	0.765	1.000	1125	tags=53%, list=6%, signal=57%
40	NETPATH_IFN-ALPHA		43	0.50	1.27	0.107	0.758	1.000	2730	tags=37%, list=15%, signal=44%
41	REACTOME_DEATH_RECEPTOR__SIGNALLING		11	0.66	1.27	0.173	0.749	1.000	3048	tags=55%, list=16%, signal=65%
42	REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS		11	0.66	1.26	0.193	0.788	1.000	3048	tags=55%, list=16%, signal=65%
43	REACTOME_APC_C_MEDIATED_DEGRADATION_OF_CELL_CYCLE_PROTEINS		47	0.49	1.26	0.121	0.774	1.000	2633	tags=38%, list=14%, signal=44%
44	REACTOME_CDC20_PHOSPHO_APC_C_MEDIATED_DEGRADATION_OF_CYCLIN_A		42	0.49	1.25	0.117	0.763	1.000	2633	tags=38%, list=14%, signal=44%
45	REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE		12	0.65	1.25	0.194	0.757	1.000	1056	tags=25%, list=6%, signal=26%
46	NCI_IL23-MEDIATED SIGNALING EVENTS		65	0.45	1.24	0.096	0.802	1.000	2930	tags=37%, list=16%, signal=44%
47	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT		57	0.47	1.24	0.102	0.790	1.000	1665	tags=18%, list=9%, signal=19%
48	BIOCARTA_SEGMENTATION CLOCK		22	0.54	1.23	0.173	0.790	1.000	922	tags=14%, list=5%, signal=14%
49	REACTOME_ELECTRON_TRANSPORT_CHAIN		53	0.46	1.22	0.139	0.802	1.000	2709	tags=42%, list=15%, signal=48%
50	REACTOME_GLUCOSE_METABOLISM		54	0.45	1.21	0.152	0.840	1.000	2493	tags=31%, list=13%, signal=36%
51	BIOCARTA_STRESS INDUCTION OF HSP REGULATION		14	0.59	1.21	0.236	0.839	1.000	4330	tags=50%, list=23%, signal=65%
52	BIOCARTA_INDUCTION OF APOPTOSIS THROUGH DR3 AND DR4/5 DEATH RECEPTORS		19	0.56	1.20	0.201	0.839	1.000	2401	tags=42%, list=13%, signal=48%
53	REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1		39	0.47	1.20	0.178	0.848	1.000	2633	tags=36%, list=14%, signal=42%
54	HUMANCYC_PHOSPHOLIPID BIOSYNTHESIS I		10	0.65	1.20	0.263	0.833	1.000	1942	tags=50%, list=10%, signal=56%
55	BIOCARTA_IL 2 SIGNALING PATHWAY		14	0.59	1.19	0.252	0.831	1.000	1078	tags=29%, list=6%, signal=30%
56	REACTOME_REGULATION_OF_APC_C_ACTIVATORS_BETWEEN_G1_S_AND_EARLY_ANAPHASE		46	0.46	1.19	0.179	0.821	1.000	2633	tags=37%, list=14%, signal=43%
57	REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES		16	0.57	1.19	0.226	0.811	1.000	2087	tags=44%, list=11%, signal=49%
58	BIOCARTA_ROLE OF MEF2D IN T-CELL APOPTOSIS		25	0.52	1.19	0.213	0.799	1.000	2904	tags=52%, list=16%, signal=62%
59	NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS III		30	0.50	1.19	0.202	0.786	1.000	3249	tags=43%, list=17%, signal=52%
60	HUMANCYC_TCA CYCLE VARIATION III (EUKARYOTIC)		16	0.57	1.19	0.241	0.778	1.000	2123	tags=38%, list=11%, signal=42%
61	REACTOME_METABOLISM_OF_WATER_SOLUBLE_VITAMINS_AND_COFACTORS		19	0.54	1.19	0.259	0.781	1.000	829	tags=16%, list=4%, signal=17%
62	REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS		19	0.54	1.17	0.226	0.811	1.000	829	tags=16%, list=4%, signal=17%
63	NETPATH_TCR		105	0.40	1.17	0.130	0.802	1.000	2191	tags=28%, list=12%, signal=31%
64	HUMANCYC_SUPERPATHWAY OF CHOLESTEROL BIOSYNTHESIS		23	0.51	1.16	0.244	0.827	1.000	1125	tags=48%, list=6%, signal=51%
65	REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1		36	0.47	1.16	0.224	0.839	1.000	2633	tags=36%, list=14%, signal=42%
66	NCI_ARF1 PATHWAY		13	0.58	1.15	0.298	0.850	1.000	2498	tags=54%, list=13%, signal=62%
67	REACTOME_DIABETES_PATHWAYS		159	0.37	1.15	0.114	0.840	1.000	2709	tags=29%, list=15%, signal=34%
68	REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE__ODC_		38	0.46	1.15	0.242	0.831	1.000	2633	tags=34%, list=14%, signal=40%
69	BIOCARTA_EPO SIGNALING PATHWAY		11	0.60	1.15	0.302	0.827	1.000	1132	tags=27%, list=6%, signal=29%
70	NCI_PDGFR-BETA SIGNALING PATHWAY		51	0.44	1.15	0.234	0.819	1.000	2730	tags=27%, list=15%, signal=32%
71	BIOCARTA_ACTIVATION OF PKC THROUGH G-PROTEIN COUPLED RECEPTORS		10	0.61	1.14	0.342	0.837	1.000	4549	tags=50%, list=24%, signal=66%
72	REACTOME_VPU_MEDIATED_DEGRADATION_OF_CD4		35	0.46	1.14	0.238	0.826	1.000	2633	tags=37%, list=14%, signal=43%
73	HUMANCYC_PHOSPHOLIPID BIOSYNTHESIS II		22	0.51	1.14	0.257	0.822	1.000	2718	tags=41%, list=15%, signal=48%
74	REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1		35	0.45	1.14	0.242	0.813	1.000	2633	tags=37%, list=14%, signal=43%
75	NCI_IL12 SIGNALING MEDIATED BY STAT4		28	0.49	1.14	0.269	0.802	1.000	2171	tags=32%, list=12%, signal=36%
76	REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX		39	0.45	1.13	0.237	0.803	1.000	3027	tags=38%, list=16%, signal=46%
77	REACTOME_INTEGRATION_OF_ENERGY_METABOLISM		109	0.38	1.13	0.193	0.805	1.000	2709	tags=35%, list=15%, signal=41%
78	REACTOME_SIGNALING_BY_WNT		37	0.46	1.13	0.257	0.796	1.000	2633	tags=38%, list=14%, signal=44%
79	REACTOME_ORNITHINE_METABOLISM		43	0.43	1.12	0.253	0.809	1.000	2776	tags=33%, list=15%, signal=38%
80	REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G		37	0.45	1.12	0.273	0.801	1.000	2633	tags=35%, list=14%, signal=41%
81	INOH_GROWTH HORMONE SIGNALING PATHWAY(JAK2 STAT5)		10	0.60	1.12	0.333	0.794	1.000	1078	tags=10%, list=6%, signal=11%
82	NCI_AURORA A SIGNALING		58	0.41	1.11	0.262	0.826	1.000	2930	tags=38%, list=16%, signal=45%
83	REACTOME_UBIQUITIN_DEPENDENT_DEGRADATION_OF_CYCLIN_D		36	0.45	1.10	0.292	0.837	1.000	2633	tags=36%, list=14%, signal=42%
84	INOH_CYTOKINE RECEPTOR DEGRADATION SIGNALING		20	0.51	1.10	0.326	0.827	1.000	1403	tags=30%, list=8%, signal=32%
85	REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION		10	0.58	1.10	0.338	0.833	1.000	991	tags=20%, list=5%, signal=21%
86	REACTOME_UBIQUITIN_DEPENDENT_DEGRADATION_OF_CYCLIN_D1		36	0.45	1.10	0.311	0.825	1.000	2633	tags=36%, list=14%, signal=42%
87	BIOCARTA_IL 3 SIGNALING PATHWAY		11	0.58	1.09	0.371	0.825	1.000	1132	tags=27%, list=6%, signal=29%
88	INOH_NEGATIVE REGULATION OF (G ALPHA I GDP-GTP EXCHANGE SIGNALING)		16	0.51	1.09	0.329	0.822	1.000	3517	tags=25%, list=19%, signal=31%
89	REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C		38	0.44	1.09	0.314	0.823	1.000	2633	tags=34%, list=14%, signal=40%
90	BIOCARTA_IL 4 SIGNALING PATHWAY		11	0.57	1.09	0.352	0.816	1.000	422	tags=27%, list=2%, signal=28%
91	INOH_NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)		16	0.51	1.09	0.342	0.808	1.000	3517	tags=25%, list=19%, signal=31%
92	REACTOME_REGULATION_OF_ACTIVATED_PAK_2P34_BY_PROTEASOME_MEDIATED_DEGRADATION1		34	0.45	1.09	0.297	0.800	1.000	2633	tags=35%, list=14%, signal=41%
93	REACTOME_INORGANIC_CATION_ANION_SLC_TRANSPORTERS		12	0.56	1.09	0.377	0.792	1.000	1574	tags=17%, list=8%, signal=18%
94	REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING		12	0.55	1.08	0.391	0.801	1.000	1845	tags=42%, list=10%, signal=46%
95	REACTOME_REGULATION_OF_APOPTOSIS		36	0.43	1.08	0.310	0.799	1.000	2633	tags=33%, list=14%, signal=39%
96	NCI_AURORA B SIGNALING		33	0.44	1.08	0.318	0.799	1.000	3010	tags=39%, list=16%, signal=47%
97	REACTOME_PEROXISOMAL_LIPID_METABOLISM		12	0.56	1.08	0.367	0.791	1.000	3181	tags=42%, list=17%, signal=50%
98	REACTOME_ORNITHINE_AND_PROLINE_METABOLISM		46	0.41	1.08	0.305	0.787	1.000	2776	tags=33%, list=15%, signal=38%
99	NCI_IL12-MEDIATED SIGNALING EVENTS		104	0.37	1.08	0.275	0.780	1.000	2930	tags=32%, list=16%, signal=37%
100	REACTOME_STABILIZATION_OF_P53		37	0.43	1.07	0.315	0.779	1.000	2633	tags=35%, list=14%, signal=41%
101	REACTOME_REGULATION_OF_ACTIVATED_PAK_2P34_BY_PROTEASOME_MEDIATED_DEGRADATION		35	0.44	1.07	0.345	0.796	1.000	2633	tags=34%, list=14%, signal=40%
102	NCI_S1P1 PATHWAY		64	0.39	1.06	0.322	0.809	1.000	2730	tags=23%, list=15%, signal=27%
103	INOH_NEGATIVE REGULATION OF (G ALPHA GDP-GTP EXCHANGE SIGNALING)		16	0.51	1.05	0.400	0.814	1.000	3517	tags=25%, list=19%, signal=31%
104	REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING		15	0.50	1.05	0.410	0.826	1.000	1196	tags=27%, list=6%, signal=28%
105	REACTOME_SCF_SKP2__MEDIATED_DEGRADATION_OF_P27_P21		37	0.42	1.05	0.362	0.824	1.000	2633	tags=35%, list=14%, signal=41%
106	REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION		11	0.56	1.05	0.428	0.817	1.000	4442	tags=64%, list=24%, signal=84%
107	BIOCARTA_THE 41BB-DEPENDENT IMMUNE RESPONSE		13	0.53	1.05	0.419	0.812	1.000	2332	tags=31%, list=13%, signal=35%
108	NCI_DOWNSTREAM SIGNALING IN NAÔVE CD8+ T CELLS		48	0.41	1.05	0.375	0.807	1.000	2345	tags=31%, list=13%, signal=36%
109	BIOCARTA_TPO SIGNALING PATHWAY		22	0.47	1.05	0.369	0.799	1.000	2259	tags=32%, list=12%, signal=36%
110	REACTOME_METABOLISM_OF_AMINO_ACIDS		106	0.36	1.04	0.322	0.794	1.000	2152	tags=21%, list=12%, signal=23%
111	BIOCARTA_RAC1 CELL MOTILITY SIGNALING PATHWAY		29	0.44	1.04	0.378	0.792	1.000	1466	tags=17%, list=8%, signal=19%
112	NCI_SIGNALING BY AURORA KINASES		85	0.37	1.04	0.336	0.794	1.000	3102	tags=36%, list=17%, signal=44%
113	BIOCARTA_INACTIVATION OF GSK3 BY AKT CAUSES ACCUMULATION OF B-CATENIN IN ALVEOLAR MACROPHAGES		38	0.41	1.04	0.365	0.797	1.000	2353	tags=24%, list=13%, signal=27%
114	REACTOME_TCR_SIGNALING		32	0.43	1.04	0.411	0.793	1.000	2191	tags=34%, list=12%, signal=39%
115	REACTOME_P53_INDEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT		35	0.42	1.03	0.399	0.795	1.000	2633	tags=34%, list=14%, signal=40%
116	REACTOME_ASSEMBLY_OF_THE_PRE_REPLICATIVE_COMPLEX		46	0.40	1.03	0.377	0.793	1.000	3027	tags=35%, list=16%, signal=41%
117	REACTOME_CLATHRIN_DERIVED_VESICLE_BUDDING		15	0.50	1.03	0.415	0.787	1.000	1196	tags=27%, list=6%, signal=28%
118	REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE		39	0.40	1.03	0.390	0.791	1.000	2633	tags=33%, list=14%, signal=39%
119	REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6		35	0.42	1.03	0.391	0.788	1.000	2633	tags=34%, list=14%, signal=40%
120	REACTOME_M_PHASE		40	0.40	1.02	0.376	0.790	1.000	2189	tags=28%, list=12%, signal=31%
121	REACTOME_P53_INDEPENDENT_DNA_DAMAGE_RESPONSE		35	0.42	1.02	0.380	0.792	1.000	2633	tags=34%, list=14%, signal=40%
122	REACTOME_AMINE_LIGAND_BINDING_RECEPTORS		12	0.52	1.02	0.461	0.793	1.000	5336	tags=33%, list=29%, signal=47%
123	NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS I		90	0.35	1.02	0.396	0.787	1.000	3306	tags=36%, list=18%, signal=43%
124	REACTOME_UBIQUITIN_MEDIATED_DEGRADATION_OF_PHOSPHORYLATED_CDC25A		35	0.42	1.02	0.409	0.782	1.000	2633	tags=34%, list=14%, signal=40%
125	INOH_[NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)		17	0.49	1.02	0.431	0.779	1.000	3517	tags=24%, list=19%, signal=29%
126	REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS		110	0.34	1.02	0.404	0.773	1.000	1125	tags=15%, list=6%, signal=15%
127	REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER		17	0.47	1.01	0.415	0.777	1.000	2403	tags=47%, list=13%, signal=54%
128	REACTOME_DUAL_INCISION_REACTION_IN_GG_NER		17	0.47	1.01	0.442	0.771	1.000	2403	tags=47%, list=13%, signal=54%
129	NCI_IL4-MEDIATED SIGNALING EVENTS		58	0.38	1.01	0.408	0.767	1.000	1934	tags=21%, list=10%, signal=23%
130	REACTOME_P53_DEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT		39	0.40	1.00	0.421	0.782	1.000	2633	tags=33%, list=14%, signal=39%
131	REACTOME_M_G1_TRANSITION		46	0.40	1.00	0.455	0.778	1.000	3027	tags=35%, list=16%, signal=41%
132	REACTOME_DOWNSTREAM_TCR_SIGNALING		19	0.46	1.00	0.445	0.772	1.000	2888	tags=47%, list=16%, signal=56%
133	INOH_TGF BETA RECEPTOR I DEGRADATION SIGNALING		25	0.44	1.00	0.455	0.785	1.000	1403	tags=20%, list=8%, signal=22%
134	NCI_TCR SIGNALING IN NAÔVE CD8+ T CELLS		108	0.34	0.99	0.456	0.788	1.000	2730	tags=31%, list=15%, signal=36%
135	REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS		75	0.35	0.99	0.464	0.787	1.000	2730	tags=31%, list=15%, signal=36%
136	REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY		22	0.43	0.99	0.466	0.787	1.000	2924	tags=36%, list=16%, signal=43%
137	REACTOME_CELL_CYCLE_CHECKPOINTS		75	0.35	0.99	0.422	0.783	1.000	2633	tags=29%, list=14%, signal=34%
138	REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER		10	0.52	0.99	0.489	0.787	1.000	4442	tags=60%, list=24%, signal=79%
139	NCI_ALPHA-SYNUCLEIN SIGNALING		32	0.41	0.98	0.478	0.799	1.000	2889	tags=22%, list=16%, signal=26%
140	HUMANCYC_SUPERPATHWAY OF GLYOXYLATE CYCLE		10	0.51	0.98	0.486	0.798	1.000	2990	tags=40%, list=16%, signal=48%
141	REACTOME_MITOTIC_PROMETAPHASE		38	0.39	0.97	0.479	0.800	1.000	2189	tags=26%, list=12%, signal=30%
142	INOH_TGF BETA RECEPTOR COMPLEX DEGRADATION SIGNALING		29	0.41	0.97	0.502	0.808	1.000	1403	tags=21%, list=8%, signal=22%
143	REACTOME_SWITCHING_OF_ORIGINS_TO_A_POST_REPLICATIVE_STATE		46	0.37	0.97	0.500	0.803	1.000	3027	tags=35%, list=16%, signal=41%
144	BIOCARTA_NF-KB SIGNALING PATHWAY		20	0.44	0.97	0.501	0.806	1.000	2345	tags=35%, list=13%, signal=40%
145	REACTOME_TOLL_LIKE_RECEPTOR_3__TLR3__CASCADE		14	0.47	0.96	0.499	0.804	1.000	1993	tags=36%, list=11%, signal=40%
146	REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION		14	0.48	0.96	0.511	0.814	1.000	2304	tags=43%, list=12%, signal=49%
147	REACTOME_REMOVAL_OF_LICENSING_FACTORS_FROM_ORIGINS		48	0.37	0.96	0.526	0.812	1.000	3027	tags=33%, list=16%, signal=40%
148	BIOCARTA_DOUBLE STRANDED RNA INDUCED GENE EXPRESSION		12	0.49	0.96	0.534	0.809	1.000	1993	tags=42%, list=11%, signal=47%
149	REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS		12	0.49	0.96	0.522	0.806	1.000	1196	tags=25%, list=6%, signal=27%
150	REACTOME_ORC1_REMOVAL_FROM_CHROMATIN		46	0.37	0.95	0.557	0.828	1.000	3027	tags=35%, list=16%, signal=41%
151	BIOCARTA_RHO CELL MOTILITY SIGNALING PATHWAY		24	0.41	0.95	0.501	0.824	1.000	2043	tags=29%, list=11%, signal=33%
152	REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE		15	0.47	0.95	0.557	0.819	1.000	690	tags=13%, list=4%, signal=14%
153	REACTOME_G1_S_DNA_DAMAGE_CHECKPOINTS		40	0.38	0.94	0.567	0.817	1.000	2633	tags=33%, list=14%, signal=38%
154	REACTOME_REGULATION_OF_DNA_REPLICATION		49	0.36	0.94	0.567	0.836	1.000	3027	tags=33%, list=16%, signal=39%
155	BIOCARTA_T CELL RECEPTOR SIGNALING PATHWAY		45	0.36	0.93	0.567	0.834	1.000	2259	tags=33%, list=12%, signal=38%
156	BIOCARTA_PROTEASOME COMPLEX		22	0.42	0.93	0.573	0.843	1.000	3301	tags=45%, list=18%, signal=55%
157	NETPATH_IL2		61	0.34	0.92	0.604	0.852	1.000	1878	tags=21%, list=10%, signal=24%
158	CELLMAP_KITRECEPTOR		49	0.36	0.92	0.589	0.854	1.000	2259	tags=27%, list=12%, signal=30%
159	REACTOME_APOPTOSIS		94	0.32	0.92	0.625	0.860	1.000	2633	tags=26%, list=14%, signal=30%
160	NETPATH_CD40		30	0.39	0.92	0.602	0.856	1.000	2930	tags=33%, list=16%, signal=39%
161	HUMANCYC_RESPIRATION (ANAEROBIC)		16	0.43	0.91	0.611	0.870	1.000	860	tags=19%, list=5%, signal=20%
162	REACTOME_TRNA_AMINOACYLATION		18	0.43	0.91	0.574	0.867	1.000	2304	tags=33%, list=12%, signal=38%
163	REACTOME_CYCLIN_A_CDK2_ASSOCIATED_EVENTS_AT_S_PHASE_ENTRY		43	0.36	0.90	0.641	0.877	1.000	2633	tags=33%, list=14%, signal=38%
164	NETPATH_EPO		39	0.35	0.90	0.660	0.883	1.000	1751	tags=26%, list=9%, signal=28%
165	REACTOME_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS		11	0.46	0.89	0.611	0.903	1.000	4917	tags=45%, list=26%, signal=62%
166	HUMANCYC_ISOLEUCINE DEGRADATION III		13	0.45	0.88	0.619	0.910	1.000	2231	tags=31%, list=12%, signal=35%
167	INOH_SNON DEGRADATION SIGNALING		25	0.37	0.88	0.662	0.915	1.000	1403	tags=24%, list=8%, signal=26%
168	NCI_ATYPICAL NF-KAPPAB PATHWAY		14	0.44	0.88	0.635	0.913	1.000	2730	tags=36%, list=15%, signal=42%
169	HUMANCYC_GLUTATHIONE-MEDIATED DETOXIFICATION		16	0.42	0.88	0.623	0.911	1.000	1549	tags=19%, list=8%, signal=20%
170	REACTOME_PHASE_II_CONJUGATION		17	0.41	0.87	0.640	0.911	1.000	998	tags=12%, list=5%, signal=12%
171	BIOCARTA_ACTIVATION OF CSK BY CAMP-DEPENDENT PROTEIN KINASE INHIBITS SIGNALING THROUGH THE T CELL RECEPTOR		36	0.35	0.86	0.718	0.946	1.000	2087	tags=28%, list=11%, signal=31%
172	NETPATH_THROMBOPOIETIN		40	0.34	0.85	0.728	0.957	1.000	1478	tags=20%, list=8%, signal=22%
173	INOH_GENE EXPRESSION OF SMAD7 BY R-SMAD:SMAD4		35	0.34	0.84	0.728	0.969	1.000	1403	tags=17%, list=8%, signal=19%
174	BIOCARTA_ERYTHROPOIETIN MEDIATED NEUROPROTECTION THROUGH NF-KB		12	0.43	0.84	0.676	0.966	1.000	1529	tags=25%, list=8%, signal=27%
175	NCI_CALCIUM SIGNALING IN THE CD4+ TCR PATHWAY		22	0.38	0.83	0.733	0.979	1.000	795	tags=9%, list=4%, signal=9%
176	NCI_EPO SIGNALING PATHWAY		32	0.35	0.83	0.764	0.979	1.000	1478	tags=19%, list=8%, signal=20%
177	BIOCARTA_CHROMATIN REMODELING BY HSWI/SNF ATP-DEPENDENT COMPLEXES		15	0.40	0.83	0.717	0.980	1.000	2468	tags=40%, list=13%, signal=46%
178	BIOCARTA_WNT SIGNALING PATHWAY		28	0.35	0.83	0.785	0.981	1.000	2353	tags=18%, list=13%, signal=20%
179	REACTOME_SEMAPHORIN_INTERACTIONS		30	0.34	0.82	0.784	0.982	1.000	1934	tags=30%, list=10%, signal=33%
180	BIOCARTA_GAMMA-AMINOBUTYRIC ACID RECEPTOR LIFE CYCLE PATHWAY		14	0.40	0.82	0.715	0.983	1.000	2659	tags=21%, list=14%, signal=25%
181	INOH_RAP1 ACTIVATION SIGNALING (THROUGH CAMP AND EPAC)		22	0.36	0.81	0.756	0.990	1.000	1466	tags=23%, list=8%, signal=25%
182	HUMANCYC_COLANIC ACID BUILDING BLOCKS BIOSYNTHESIS		10	0.43	0.81	0.742	0.987	1.000	2800	tags=40%, list=15%, signal=47%
183	NCI_EPHA FORWARD SIGNALING		30	0.33	0.80	0.819	0.996	1.000	3010	tags=17%, list=16%, signal=20%
184	BIOCARTA_APOPTOTIC SIGNALING IN RESPONSE TO DNA DAMAGE		14	0.40	0.80	0.723	1.000	1.000	1729	tags=21%, list=9%, signal=24%
185	REACTOME_TRAF6_MEDIATED_INDUCTION_OF_THE_ANTIVIRAL_CYTOKINE_IFN_ALPHA_BETA_CASCADE		12	0.40	0.79	0.773	1.000	1.000	1993	tags=33%, list=11%, signal=37%
186	BIOCARTA_IL-7 SIGNAL TRANSDUCTION		14	0.38	0.79	0.788	1.000	1.000	1078	tags=14%, list=6%, signal=15%
187	BIOCARTA_REGULATION OF TRANSCRIPTIONAL ACTIVITY BY PML		10	0.42	0.79	0.753	1.000	1.000	2666	tags=30%, list=14%, signal=35%
188	BIOCARTA_EGF SIGNALING PATHWAY		18	0.36	0.78	0.796	1.000	1.000	2259	tags=28%, list=12%, signal=32%
189	REACTOME_STEROID_HORMONES		13	0.40	0.78	0.754	1.000	1.000	3461	tags=15%, list=19%, signal=19%
190	BIOCARTA_LISSENCEPHALY GENE (LIS1) IN NEURONAL MIGRATION AND DEVELOPMENT		15	0.38	0.78	0.779	1.000	1.000	1832	tags=20%, list=10%, signal=22%
191	BIOCARTA_VISUAL SIGNAL TRANSDUCTION		13	0.39	0.78	0.790	1.000	1.000	2780	tags=23%, list=15%, signal=27%
192	BIOCARTA_ROLE OF MAL IN RHO-MEDIATED ACTIVATION OF SRF		17	0.37	0.77	0.795	1.000	1.000	3086	tags=53%, list=17%, signal=63%
193	BIOCARTA_CHAPERONES MODULATE INTERFERON SIGNALING PATHWAY		16	0.38	0.77	0.781	1.000	1.000	2206	tags=31%, list=12%, signal=35%
194	BIOCARTA_IL 6 SIGNALING PATHWAY		13	0.39	0.77	0.808	1.000	1.000	2414	tags=31%, list=13%, signal=35%
195	HUMANCYC_NAD/NADH PHOSPHORYLATION AND DEPHOSPHORYLATION		30	0.32	0.76	0.841	1.000	1.000	2254	tags=27%, list=12%, signal=30%
196	BIOCARTA_TELOMERES TELOMERASE CELLULAR AGING AND IMMORTALITY		15	0.38	0.76	0.789	1.000	1.000	2468	tags=27%, list=13%, signal=31%
197	REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING		12	0.39	0.76	0.809	0.997	1.000	2692	tags=50%, list=14%, signal=58%
198	REACTOME_MEMBRANE_TRAFFICKING		26	0.33	0.76	0.858	0.995	1.000	2791	tags=31%, list=15%, signal=36%
199	INOH_GENE EXPRESSION OF SOCS BY STAT DIMER		13	0.38	0.76	0.804	0.994	1.000	2171	tags=46%, list=12%, signal=52%
200	BIOCARTA_IL12 AND STAT4 DEPENDENT SIGNALING PATHWAY IN TH1 DEVELOPMENT		15	0.37	0.76	0.820	0.990	1.000	1321	tags=20%, list=7%, signal=22%
201	BIOCARTA_TNFR1 SIGNALING PATHWAY		16	0.36	0.75	0.829	0.987	1.000	3341	tags=50%, list=18%, signal=61%
202	REACTOME_ABORTIVE_ELONGATION_OF_HIV_1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT		14	0.38	0.75	0.804	0.983	1.000	2468	tags=29%, list=13%, signal=33%
203	REACTOME_MRNA_CAPPING		21	0.34	0.75	0.855	0.979	1.000	2468	tags=33%, list=13%, signal=38%
204	NCI_JNK SIGNALING IN THE CD4+ TCR PATHWAY		33	0.31	0.75	0.903	0.976	1.000	795	tags=9%, list=4%, signal=9%
205	BIOCARTA_SIGNAL TRANSDUCTION THROUGH IL1R		34	0.31	0.75	0.898	0.973	1.000	2466	tags=24%, list=13%, signal=27%
206	BIOCARTA_REGULATION OF EIF2		10	0.40	0.75	0.808	0.975	1.000	1350	tags=30%, list=7%, signal=32%
207	BIOCARTA_CELL CYCLE: G2/M CHECKPOINT		19	0.34	0.74	0.860	0.977	1.000	3036	tags=26%, list=16%, signal=31%
208	HUMANCYC_DE NOVO BIOSYNTHESIS OF PYRIMIDINE RIBONUCLEOTIDES		11	0.39	0.74	0.823	0.973	1.000	1562	tags=27%, list=8%, signal=30%
209	HUMANCYC_GLYCINE BETAINE DEGRADATION		10	0.39	0.73	0.822	0.976	1.000	1487	tags=20%, list=8%, signal=22%
210	REACTOME_MRNA_PROCESSING		24	0.33	0.73	0.881	0.974	1.000	2468	tags=33%, list=13%, signal=38%
211	BIOCARTA_ROLE OF RAN IN MITOTIC SPINDLE REGULATION		11	0.38	0.73	0.843	0.970	1.000	3514	tags=45%, list=19%, signal=56%
212	REACTOME_TAT_MEDIATED_HIV_1_ELONGATION_ARREST_AND_RECOVERY_		19	0.33	0.73	0.854	0.969	1.000	2468	tags=26%, list=13%, signal=30%
213	REACTOME_HIV_1_ELONGATION_ARREST_AND_RECOVERY		20	0.33	0.73	0.870	0.967	1.000	2468	tags=25%, list=13%, signal=29%
214	HUMANCYC_FATTY ACID BETA-OXIDATION I		16	0.35	0.72	0.887	0.967	1.000	4157	tags=38%, list=22%, signal=48%
215	NCI_IL2 SIGNALING EVENTS MEDIATED BY STAT5		29	0.31	0.72	0.914	0.969	1.000	187	tags=7%, list=1%, signal=7%
216	REACTOME_ELONGATION_ARREST_AND_RECOVERY		20	0.33	0.71	0.887	0.968	1.000	2468	tags=25%, list=13%, signal=29%
217	REACTOME_PAUSING_AND_RECOVERY_OF_HIV_1_ELONGATION		20	0.33	0.71	0.907	0.970	1.000	2468	tags=25%, list=13%, signal=29%
218	REACTOME_PAUSING_AND_RECOVERY_OF_TAT_MEDIATED_HIV_1_ELONGATION		19	0.33	0.70	0.912	0.968	1.000	2468	tags=26%, list=13%, signal=30%
219	REACTOME_PAUSING_AND_RECOVERY_OF_ELONGATION		20	0.33	0.70	0.918	0.968	1.000	2468	tags=25%, list=13%, signal=29%
220	BIOCARTA_MECHANISM OF PROTEIN IMPORT INTO THE NUCLEUS		11	0.36	0.69	0.884	0.969	1.000	2036	tags=27%, list=11%, signal=31%
221	REACTOME_G_PROTEIN_MEDIATED_EVENTS		11	0.36	0.68	0.892	0.971	1.000	614	tags=9%, list=3%, signal=9%
222	BIOCARTA_NUCLEAR RECEPTORS COORDINATE THE ACTIVITIES OF CHROMATIN REMODELING COMPLEXES AND COACTIVATORS TO FACILITATE INITIATION OF TRANSCRIPTION IN CARCINOMA CELLS		14	0.34	0.68	0.903	0.968	1.000	3090	tags=29%, list=17%, signal=34%
223	REACTOME_PLC_BETA_MEDIATED_EVENTS		10	0.36	0.67	0.907	0.970	1.000	614	tags=10%, list=3%, signal=10%
224	REACTOME_PROTEIN_FOLDING		13	0.33	0.66	0.925	0.975	1.000	1625	tags=23%, list=9%, signal=25%
225	REACTOME_RAS_ACTIVATION_UOPN_CA2__INFUX_THROUGH_NMDA_RECEPTOR		10	0.35	0.66	0.907	0.970	1.000	472	tags=10%, list=3%, signal=10%
226	BIOCARTA_ADP-RIBOSYLATION FACTOR		18	0.30	0.63	0.957	0.980	1.000	4122	tags=39%, list=22%, signal=50%
227	HUMANCYC_FATTY ACID BETA-OXIDATION II (CORE PATHWAY)		16	0.27	0.57	0.984	0.992	1.000	4157	tags=31%, list=22%, signal=40%
228	HUMANCYC_PHOSPHOLIPASES		22	0.21	0.46	1.000	0.997	1.000	3947	tags=18%, list=21%, signal=23%