Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
| Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
| Upregulated in class | wtNotch |
| GeneSet | REGULATION_OF_DNA_METABOLIC_PROCESS |
| Enrichment Score (ES) | -0.6536892 |
| Normalized Enrichment Score (NES) | -1.6544853 |
| Nominal p-value | 0.0054054055 |
| FDR q-value | 0.26208127 |
| FWER p-Value | 0.86 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ERCC1 | 3800010 4590132 4670397 | 493 | 2.149 | 0.0390 | No | ||
| 2 | TNFSF13 | 2650170 | 927 | 1.692 | 0.0673 | No | ||
| 3 | TGFB1 | 1940162 | 2867 | 0.610 | -0.0184 | No | ||
| 4 | UBE2V1 | 2470093 | 4142 | 0.295 | -0.0780 | No | ||
| 5 | GLI2 | 3060632 | 4310 | 0.270 | -0.0788 | No | ||
| 6 | S100A11 | 2260064 | 4970 | 0.194 | -0.1083 | No | ||
| 7 | UBE2N | 520369 2900047 | 5583 | 0.144 | -0.1369 | No | ||
| 8 | IL4 | 6020537 | 6002 | 0.119 | -0.1557 | No | ||
| 9 | UBE2V2 | 4210484 | 6707 | 0.087 | -0.1910 | No | ||
| 10 | SET | 6650286 | 9446 | 0.021 | -0.3377 | No | ||
| 11 | WRNIP1 | 2320541 5890725 | 10647 | 0.001 | -0.4023 | No | ||
| 12 | EREG | 50519 4920129 | 10683 | 0.001 | -0.4041 | No | ||
| 13 | RAD9A | 110300 1940632 3990390 6040014 | 11770 | -0.018 | -0.4620 | No | ||
| 14 | GLI1 | 4560176 | 11980 | -0.022 | -0.4726 | No | ||
| 15 | NF2 | 4150735 6450139 | 12588 | -0.036 | -0.5042 | No | ||
| 16 | NBN | 730538 2470619 4780594 | 13322 | -0.060 | -0.5418 | No | ||
| 17 | PPARGC1A | 4670040 | 13995 | -0.094 | -0.5751 | No | ||
| 18 | RAD51 | 6110450 6980280 | 15117 | -0.225 | -0.6286 | No | ||
| 19 | IL7R | 2060088 6380500 | 15265 | -0.254 | -0.6287 | No | ||
| 20 | CDK2 | 130484 2260301 4010088 5050110 | 15400 | -0.284 | -0.6273 | No | ||
| 21 | RAD17 | 5220739 | 15422 | -0.288 | -0.6196 | No | ||
| 22 | TERF2IP | 580010 870364 2190358 | 15893 | -0.433 | -0.6317 | No | ||
| 23 | RAD50 | 4050184 6770746 | 16302 | -0.577 | -0.6361 | Yes | ||
| 24 | CDC6 | 4570296 5360600 | 16457 | -0.641 | -0.6248 | Yes | ||
| 25 | CDC45L | 70537 3130114 | 16566 | -0.690 | -0.6096 | Yes | ||
| 26 | MRE11A | 3850601 4670332 | 16658 | -0.748 | -0.5917 | Yes | ||
| 27 | GMNN | 2630148 | 16925 | -0.916 | -0.5780 | Yes | ||
| 28 | TIPIN | 1570301 2480113 | 17184 | -1.048 | -0.5600 | Yes | ||
| 29 | ERCC4 | 1570619 5720180 | 17223 | -1.079 | -0.5291 | Yes | ||
| 30 | CDT1 | 3780682 | 17348 | -1.186 | -0.4996 | Yes | ||
| 31 | ATR | 6860273 | 17772 | -1.606 | -0.4734 | Yes | ||
| 32 | TLK2 | 1170161 | 17903 | -1.733 | -0.4275 | Yes | ||
| 33 | TERF2 | 3840044 | 17964 | -1.793 | -0.3760 | Yes | ||
| 34 | SMARCAD1 | 5390619 | 18027 | -1.868 | -0.3224 | Yes | ||
| 35 | TLK1 | 7100605 | 18049 | -1.887 | -0.2659 | Yes | ||
| 36 | POLH | 2690528 | 18276 | -2.230 | -0.2101 | Yes | ||
| 37 | KPNA1 | 5270324 | 18312 | -2.308 | -0.1416 | Yes | ||
| 38 | GTPBP4 | 6840332 | 18347 | -2.393 | -0.0704 | Yes | ||
| 39 | KPNA2 | 3450114 | 18491 | -2.781 | 0.0067 | Yes |
