Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | wtNotch |
GeneSet | CELL_CYCLE_PHASE |
Enrichment Score (ES) | -0.5275959 |
Normalized Enrichment Score (NES) | -1.6206 |
Nominal p-value | 0.0 |
FDR q-value | 0.27002713 |
FWER p-Value | 0.956 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | CDK10 | 60164 1190717 3130128 3990044 | 93 | 3.142 | 0.0256 | No | ||
2 | BCAT1 | 3290128 4050408 | 146 | 2.890 | 0.0510 | No | ||
3 | CDK4 | 540075 4540600 | 515 | 2.120 | 0.0517 | No | ||
4 | MAD2L2 | 1240358 | 828 | 1.784 | 0.0523 | No | ||
5 | MSH5 | 1340019 4730333 | 961 | 1.651 | 0.0612 | No | ||
6 | CHMP1A | 5550441 | 965 | 1.647 | 0.0771 | No | ||
7 | CDC25B | 6940102 | 1097 | 1.538 | 0.0850 | No | ||
8 | CHFR | 3390050 6450300 6450736 | 1489 | 1.272 | 0.0763 | No | ||
9 | MAP3K11 | 7000039 | 1593 | 1.210 | 0.0825 | No | ||
10 | POLD1 | 4830026 | 1795 | 1.079 | 0.0821 | No | ||
11 | TARDBP | 870390 2350093 | 2164 | 0.917 | 0.0712 | No | ||
12 | CDKN2C | 5050750 5130148 | 2627 | 0.707 | 0.0530 | No | ||
13 | STAG3 | 3830112 | 2683 | 0.682 | 0.0567 | No | ||
14 | TGFB1 | 1940162 | 2867 | 0.610 | 0.0528 | No | ||
15 | NUMA1 | 6520576 | 3038 | 0.548 | 0.0489 | No | ||
16 | BOLL | 6100743 | 3048 | 0.545 | 0.0537 | No | ||
17 | E2F1 | 5360093 | 3237 | 0.483 | 0.0483 | No | ||
18 | TOP3A | 7000435 | 3266 | 0.476 | 0.0514 | No | ||
19 | CDK6 | 4920253 | 3281 | 0.469 | 0.0552 | No | ||
20 | APBB1 | 2690338 | 3475 | 0.422 | 0.0489 | No | ||
21 | CDKN2D | 6040035 | 3716 | 0.370 | 0.0395 | No | ||
22 | DCTN2 | 540471 3780717 | 3928 | 0.333 | 0.0313 | No | ||
23 | CUL2 | 4200278 | 4121 | 0.298 | 0.0238 | No | ||
24 | RAD54L | 2970041 | 4258 | 0.276 | 0.0192 | No | ||
25 | TPD52L1 | 4590711 5570575 | 4391 | 0.260 | 0.0146 | No | ||
26 | RCC1 | 2480358 | 4488 | 0.246 | 0.0118 | No | ||
27 | ACVR1 | 6840671 | 4652 | 0.228 | 0.0052 | No | ||
28 | DUSP13 | 6400152 | 4807 | 0.211 | -0.0011 | No | ||
29 | ANAPC11 | 1780601 | 5028 | 0.189 | -0.0112 | No | ||
30 | CDKN2B | 6020040 | 5044 | 0.187 | -0.0102 | No | ||
31 | ANLN | 1780113 2470537 6840047 | 5049 | 0.187 | -0.0086 | No | ||
32 | UBE2C | 6130017 | 5204 | 0.173 | -0.0152 | No | ||
33 | PLK1 | 1780369 2640121 | 5389 | 0.159 | -0.0236 | No | ||
34 | CDCA5 | 5670131 | 5416 | 0.156 | -0.0235 | No | ||
35 | TBRG4 | 3610239 6370594 | 5750 | 0.133 | -0.0403 | No | ||
36 | CENPE | 2850022 | 5869 | 0.126 | -0.0454 | No | ||
37 | RAD1 | 4200551 | 5893 | 0.125 | -0.0454 | No | ||
38 | NEK6 | 3360687 | 6197 | 0.109 | -0.0608 | No | ||
39 | CUL5 | 450142 | 6527 | 0.094 | -0.0777 | No | ||
40 | DMC1 | 450341 | 6562 | 0.092 | -0.0786 | No | ||
41 | CLIP1 | 2850162 6770397 | 6789 | 0.084 | -0.0900 | No | ||
42 | NEK2 | 2120520 | 7723 | 0.056 | -0.1400 | No | ||
43 | KATNA1 | 6290048 | 7912 | 0.051 | -0.1497 | No | ||
44 | APBB2 | 5130403 | 7933 | 0.051 | -0.1502 | No | ||
45 | CETN1 | 6020056 | 7956 | 0.050 | -0.1509 | No | ||
46 | PRMT5 | 2760180 4590072 | 8107 | 0.047 | -0.1586 | No | ||
47 | TTN | 2320161 4670056 6550026 | 8471 | 0.039 | -0.1779 | No | ||
48 | CDKN3 | 110520 | 8482 | 0.039 | -0.1780 | No | ||
49 | TIMELESS | 3710315 | 8536 | 0.038 | -0.1805 | No | ||
50 | KIF11 | 5390139 | 9245 | 0.025 | -0.2186 | No | ||
51 | POLA1 | 4760541 | 9609 | 0.018 | -0.2381 | No | ||
52 | MSH4 | 3940068 | 9622 | 0.018 | -0.2386 | No | ||
53 | BUB1 | 5390270 | 10159 | 0.009 | -0.2675 | No | ||
54 | EREG | 50519 4920129 | 10683 | 0.001 | -0.2958 | No | ||
55 | CCNA1 | 6290113 | 10793 | -0.001 | -0.3017 | No | ||
56 | KIF2C | 6940082 | 11750 | -0.018 | -0.3533 | No | ||
57 | CDKN1A | 4050088 6400706 | 11801 | -0.019 | -0.3558 | No | ||
58 | RAN | 2260446 4590647 | 11827 | -0.019 | -0.3570 | No | ||
59 | ANAPC10 | 870086 1170037 2260129 | 11843 | -0.019 | -0.3576 | No | ||
60 | PAM | 5290528 | 11865 | -0.020 | -0.3585 | No | ||
61 | CENPF | 5050088 | 11951 | -0.022 | -0.3629 | No | ||
62 | SPO11 | 540288 4780239 | 12023 | -0.023 | -0.3665 | No | ||
63 | TTK | 3800129 | 12149 | -0.026 | -0.3731 | No | ||
64 | RAD52 | 110093 | 12754 | -0.041 | -0.4054 | No | ||
65 | EPGN | 6980450 | 13283 | -0.059 | -0.4334 | No | ||
66 | CHEK1 | 50167 1940300 | 13289 | -0.059 | -0.4331 | No | ||
67 | NBN | 730538 2470619 4780594 | 13322 | -0.060 | -0.4342 | No | ||
68 | KIF15 | 610731 4070731 6520014 | 13416 | -0.064 | -0.4386 | No | ||
69 | CDC23 | 3190593 | 13459 | -0.066 | -0.4402 | No | ||
70 | PIM2 | 840136 5720692 7100577 | 13685 | -0.076 | -0.4517 | No | ||
71 | SYCP1 | 2570010 | 13761 | -0.080 | -0.4550 | No | ||
72 | DCTN3 | 6840131 | 13849 | -0.085 | -0.4588 | No | ||
73 | ATM | 3610110 4050524 | 13930 | -0.090 | -0.4623 | No | ||
74 | PML | 50093 2190435 2450402 3840082 | 13983 | -0.093 | -0.4642 | No | ||
75 | USH1C | 1570372 4230364 | 14222 | -0.110 | -0.4760 | No | ||
76 | CDC25C | 2570673 4760161 6520707 | 14375 | -0.124 | -0.4830 | No | ||
77 | DDX11 | 6590671 | 14481 | -0.133 | -0.4874 | No | ||
78 | CDKN1B | 3800025 6450044 | 14572 | -0.142 | -0.4909 | No | ||
79 | NPM2 | 6040139 | 14613 | -0.148 | -0.4916 | No | ||
80 | SMC3 | 870546 1400411 5700039 6450577 | 14706 | -0.158 | -0.4951 | No | ||
81 | TGFA | 1570332 | 14796 | -0.172 | -0.4982 | No | ||
82 | PIN1 | 2970408 | 14858 | -0.180 | -0.4998 | No | ||
83 | GFI1B | 4570131 | 15009 | -0.204 | -0.5059 | No | ||
84 | RAD51L1 | 4010112 5860435 | 15068 | -0.213 | -0.5069 | No | ||
85 | RAD51 | 6110450 6980280 | 15117 | -0.225 | -0.5073 | No | ||
86 | ACVR1B | 3610446 5570195 | 15345 | -0.272 | -0.5170 | No | ||
87 | CDK2 | 130484 2260301 4010088 5050110 | 15400 | -0.284 | -0.5171 | No | ||
88 | RAD17 | 5220739 | 15422 | -0.288 | -0.5155 | No | ||
89 | LATS2 | 4480593 6020494 | 15450 | -0.294 | -0.5141 | No | ||
90 | KIF22 | 1190368 | 15549 | -0.321 | -0.5162 | No | ||
91 | GFI1 | 730180 | 15709 | -0.371 | -0.5212 | No | ||
92 | NOLC1 | 2350195 | 15741 | -0.381 | -0.5192 | No | ||
93 | PPP5C | 3130047 | 15821 | -0.409 | -0.5195 | No | ||
94 | XRCC2 | 4920706 | 15972 | -0.458 | -0.5231 | Yes | ||
95 | SSSCA1 | 1240402 780309 | 16008 | -0.469 | -0.5204 | Yes | ||
96 | CUL4A | 1170088 2320008 2470278 | 16110 | -0.504 | -0.5210 | Yes | ||
97 | EGF | 5220154 | 16142 | -0.515 | -0.5177 | Yes | ||
98 | SMC4 | 5910240 | 16168 | -0.524 | -0.5139 | Yes | ||
99 | CIT | 2370601 | 16181 | -0.528 | -0.5094 | Yes | ||
100 | SUGT1 | 1690670 | 16186 | -0.532 | -0.5044 | Yes | ||
101 | RAD50 | 4050184 6770746 | 16302 | -0.577 | -0.5050 | Yes | ||
102 | CCNA2 | 5290075 | 16440 | -0.634 | -0.5063 | Yes | ||
103 | CDC6 | 4570296 5360600 | 16457 | -0.641 | -0.5009 | Yes | ||
104 | MRE11A | 3850601 4670332 | 16658 | -0.748 | -0.5044 | Yes | ||
105 | DLG7 | 3120041 | 16674 | -0.763 | -0.4978 | Yes | ||
106 | CDK2AP1 | 2340156 | 16688 | -0.770 | -0.4910 | Yes | ||
107 | ABL1 | 1050593 2030050 4010114 | 16718 | -0.789 | -0.4848 | Yes | ||
108 | BIRC5 | 110408 580014 1770632 | 16722 | -0.790 | -0.4773 | Yes | ||
109 | RAD21 | 1990278 | 16835 | -0.856 | -0.4750 | Yes | ||
110 | RAD51L3 | 2230609 2810286 3190008 3390053 4230168 | 16913 | -0.906 | -0.4703 | Yes | ||
111 | KNTC1 | 430079 | 16964 | -0.940 | -0.4639 | Yes | ||
112 | CDC16 | 1940706 | 17027 | -0.980 | -0.4577 | Yes | ||
113 | CD28 | 1400739 4210093 | 17038 | -0.983 | -0.4486 | Yes | ||
114 | PCBP4 | 6350722 | 17053 | -0.991 | -0.4397 | Yes | ||
115 | TIPIN | 1570301 2480113 | 17184 | -1.048 | -0.4365 | Yes | ||
116 | CDKN2A | 4670215 4760047 | 17236 | -1.090 | -0.4287 | Yes | ||
117 | ZW10 | 2900735 3520687 | 17254 | -1.103 | -0.4188 | Yes | ||
118 | SMC1A | 3060600 5700148 5890113 6370154 | 17283 | -1.130 | -0.4093 | Yes | ||
119 | AURKA | 780537 | 17299 | -1.140 | -0.3990 | Yes | ||
120 | HSPA2 | 6420592 | 17312 | -1.149 | -0.3885 | Yes | ||
121 | KHDRBS1 | 1240403 6040040 | 17319 | -1.152 | -0.3776 | Yes | ||
122 | LIG3 | 2940300 | 17350 | -1.187 | -0.3676 | Yes | ||
123 | MPHOSPH6 | 5570164 | 17437 | -1.259 | -0.3600 | Yes | ||
124 | CDKN1C | 6520577 | 17535 | -1.353 | -0.3520 | Yes | ||
125 | GSPT1 | 5420050 | 17593 | -1.408 | -0.3414 | Yes | ||
126 | ZWINT | 6940670 | 17662 | -1.481 | -0.3306 | Yes | ||
127 | NDC80 | 4120465 | 17749 | -1.583 | -0.3199 | Yes | ||
128 | PPP6C | 2450670 | 17776 | -1.613 | -0.3055 | Yes | ||
129 | PTPRC | 130402 5290148 | 17828 | -1.663 | -0.2921 | Yes | ||
130 | CUL1 | 1990632 | 17844 | -1.677 | -0.2765 | Yes | ||
131 | CDC7 | 4060546 4850041 | 17891 | -1.718 | -0.2623 | Yes | ||
132 | NUSAP1 | 940048 3120435 | 17902 | -1.733 | -0.2459 | Yes | ||
133 | ANAPC5 | 730164 7100685 | 18019 | -1.862 | -0.2340 | Yes | ||
134 | SKP2 | 360711 380093 4810368 | 18133 | -2.012 | -0.2205 | Yes | ||
135 | CUL3 | 1850520 | 18170 | -2.066 | -0.2023 | Yes | ||
136 | RB1 | 5900338 | 18226 | -2.152 | -0.1843 | Yes | ||
137 | TPX2 | 6420324 | 18310 | -2.306 | -0.1663 | Yes | ||
138 | MAD2L1 | 4480725 | 18343 | -2.379 | -0.1448 | Yes | ||
139 | ANAPC4 | 4540338 | 18344 | -2.384 | -0.1216 | Yes | ||
140 | POLE | 6020538 | 18351 | -2.398 | -0.0985 | Yes | ||
141 | BUB1B | 1450288 | 18355 | -2.413 | -0.0751 | Yes | ||
142 | KPNA2 | 3450114 | 18491 | -2.781 | -0.0553 | Yes | ||
143 | AKAP8 | 4210026 | 18559 | -3.171 | -0.0280 | Yes | ||
144 | NCAPH | 6220435 | 18560 | -3.183 | 0.0030 | Yes |