Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | V$TEF1_Q6 |
Enrichment Score (ES) | 0.4335635 |
Normalized Enrichment Score (NES) | 1.2524142 |
Nominal p-value | 0.049635038 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | MAPKAPK2 | 2850500 | 26 | 3.846 | 0.0440 | Yes | ||
2 | POLD4 | 2320082 | 55 | 3.377 | 0.0823 | Yes | ||
3 | PADI2 | 2940092 6420136 | 117 | 2.975 | 0.1141 | Yes | ||
4 | FRAG1 | 1050504 1170152 2030092 | 189 | 2.750 | 0.1427 | Yes | ||
5 | USP5 | 4850017 | 479 | 2.160 | 0.1525 | Yes | ||
6 | DPM3 | 50039 | 519 | 2.117 | 0.1754 | Yes | ||
7 | LMNA | 520471 1500075 3190167 4210020 | 720 | 1.886 | 0.1868 | Yes | ||
8 | CD2 | 430672 | 723 | 1.885 | 0.2089 | Yes | ||
9 | RAPSN | 610110 2370162 | 759 | 1.848 | 0.2288 | Yes | ||
10 | RBM14 | 5340731 5690315 | 822 | 1.791 | 0.2466 | Yes | ||
11 | PTPRF | 1770528 3190044 | 872 | 1.736 | 0.2644 | Yes | ||
12 | PEA15 | 4590685 | 911 | 1.702 | 0.2824 | Yes | ||
13 | DEDD | 6400131 | 926 | 1.693 | 0.3017 | Yes | ||
14 | SRRM1 | 6110025 | 948 | 1.674 | 0.3203 | Yes | ||
15 | RASGRP2 | 2970333 | 1071 | 1.563 | 0.3321 | Yes | ||
16 | IPO13 | 3870088 | 1234 | 1.450 | 0.3404 | Yes | ||
17 | MAST2 | 6200348 | 1275 | 1.419 | 0.3550 | Yes | ||
18 | SH3BGRL3 | 1850750 | 1565 | 1.231 | 0.3539 | Yes | ||
19 | EHD1 | 3840731 | 1743 | 1.117 | 0.3575 | Yes | ||
20 | PTPRCAP | 6650075 | 1744 | 1.116 | 0.3706 | Yes | ||
21 | NFKB2 | 2320670 | 1817 | 1.069 | 0.3794 | Yes | ||
22 | IL18BP | 3450128 | 1969 | 1.000 | 0.3830 | Yes | ||
23 | AVPI1 | 1850377 | 1986 | 0.997 | 0.3939 | Yes | ||
24 | EPHB2 | 1090288 1410377 2100541 | 1989 | 0.997 | 0.4055 | Yes | ||
25 | PIAS3 | 50204 240739 4060524 | 2050 | 0.973 | 0.4138 | Yes | ||
26 | PAQR6 | 580450 2630093 5550341 | 2548 | 0.745 | 0.3956 | Yes | ||
27 | EPC1 | 1570050 5290095 6900193 | 2559 | 0.741 | 0.4038 | Yes | ||
28 | CDKN2C | 5050750 5130148 | 2627 | 0.707 | 0.4085 | Yes | ||
29 | SIPA1 | 5220687 | 2672 | 0.687 | 0.4143 | Yes | ||
30 | ADD3 | 4150739 5390600 | 2721 | 0.663 | 0.4195 | Yes | ||
31 | CYR61 | 1240408 5290026 4120452 6550008 | 2750 | 0.650 | 0.4256 | Yes | ||
32 | ADIPOR1 | 3140440 | 2762 | 0.644 | 0.4326 | Yes | ||
33 | SWAP70 | 2810577 2850739 5130594 | 2917 | 0.593 | 0.4313 | Yes | ||
34 | SYNPO2L | 5390719 | 3111 | 0.523 | 0.4270 | Yes | ||
35 | ETV3 | 5360487 | 3201 | 0.493 | 0.4280 | Yes | ||
36 | PVRL1 | 2570167 5220519 5890500 3190309 | 3345 | 0.452 | 0.4256 | Yes | ||
37 | MCAM | 5130270 6620577 | 3406 | 0.437 | 0.4275 | Yes | ||
38 | MUC1 | 2470273 3140082 6220131 7040066 | 3431 | 0.432 | 0.4313 | Yes | ||
39 | OVOL1 | 1690131 | 3523 | 0.412 | 0.4312 | Yes | ||
40 | PAX2 | 6040270 7000133 | 3593 | 0.397 | 0.4322 | Yes | ||
41 | ELAVL4 | 50735 3360086 5220167 | 3674 | 0.381 | 0.4323 | Yes | ||
42 | USP2 | 1190292 1240253 4850035 | 3732 | 0.367 | 0.4336 | Yes | ||
43 | CUL2 | 4200278 | 4121 | 0.298 | 0.4161 | No | ||
44 | MRGPRF | 4780746 | 4364 | 0.264 | 0.4061 | No | ||
45 | SYTL2 | 580097 5390576 6770603 | 4521 | 0.241 | 0.4005 | No | ||
46 | ST5 | 3780204 | 4683 | 0.224 | 0.3944 | No | ||
47 | NNMT | 450471 | 4995 | 0.192 | 0.3798 | No | ||
48 | ABCG4 | 3440458 | 5026 | 0.189 | 0.3804 | No | ||
49 | PRKCDBP | 4210341 | 5057 | 0.186 | 0.3810 | No | ||
50 | OLFML3 | 7100463 | 5099 | 0.183 | 0.3809 | No | ||
51 | CACNA1S | 4730465 | 5400 | 0.157 | 0.3665 | No | ||
52 | DAB1 | 2060193 7000605 | 5403 | 0.157 | 0.3683 | No | ||
53 | EPHA2 | 5890056 | 5412 | 0.156 | 0.3697 | No | ||
54 | UBXD3 | 5050193 | 5754 | 0.133 | 0.3528 | No | ||
55 | VAX1 | 6660750 | 5826 | 0.129 | 0.3505 | No | ||
56 | LAMC2 | 450692 2680041 4200059 4670148 | 5842 | 0.128 | 0.3512 | No | ||
57 | MFAP5 | 4920139 | 6113 | 0.113 | 0.3379 | No | ||
58 | ELF3 | 770551 6180019 | 6222 | 0.108 | 0.3333 | No | ||
59 | CYP26A1 | 380022 2690600 | 6524 | 0.094 | 0.3181 | No | ||
60 | SYT8 | 4280551 | 6569 | 0.092 | 0.3168 | No | ||
61 | BRMS1 | 6860280 | 6664 | 0.089 | 0.3128 | No | ||
62 | HDGF | 5130114 5420066 6590152 | 6677 | 0.088 | 0.3132 | No | ||
63 | TMPRSS4 | 1050402 1710128 2480341 | 6849 | 0.082 | 0.3049 | No | ||
64 | SLC17A6 | 4210576 | 6885 | 0.080 | 0.3039 | No | ||
65 | JAM3 | 4280193 | 6985 | 0.077 | 0.2995 | No | ||
66 | IER5 | 2350575 | 7003 | 0.076 | 0.2995 | No | ||
67 | NES | 1190672 2450167 | 7025 | 0.075 | 0.2992 | No | ||
68 | PBXIP1 | 70131 | 7080 | 0.074 | 0.2972 | No | ||
69 | TNRC4 | 4050156 | 7129 | 0.072 | 0.2954 | No | ||
70 | CPT1A | 6350093 | 7308 | 0.067 | 0.2866 | No | ||
71 | ANXA8 | 4780022 | 7338 | 0.066 | 0.2858 | No | ||
72 | FOLR1 | 2470369 | 7368 | 0.065 | 0.2850 | No | ||
73 | CGN | 5890139 6370167 6400537 | 7487 | 0.062 | 0.2793 | No | ||
74 | RNF2 | 2340497 | 7708 | 0.056 | 0.2681 | No | ||
75 | RAB18 | 3120575 4590577 | 7758 | 0.055 | 0.2661 | No | ||
76 | THBS3 | 2360465 4050176 | 7970 | 0.050 | 0.2552 | No | ||
77 | LMOD1 | 2120035 | 8072 | 0.047 | 0.2503 | No | ||
78 | RTN4RL2 | 6450609 | 8091 | 0.047 | 0.2499 | No | ||
79 | SCNN1A | 4730019 | 8420 | 0.040 | 0.2326 | No | ||
80 | TNKS1BP1 | 7040184 | 8506 | 0.038 | 0.2285 | No | ||
81 | LOXL4 | 6520095 | 8605 | 0.036 | 0.2236 | No | ||
82 | POGZ | 870348 7040286 | 8639 | 0.036 | 0.2222 | No | ||
83 | WNT3A | 6350348 | 8879 | 0.031 | 0.2096 | No | ||
84 | PBX1 | 6660301 | 8912 | 0.030 | 0.2083 | No | ||
85 | DNM3 | 730711 | 9316 | 0.023 | 0.1867 | No | ||
86 | ACTA1 | 840538 | 9331 | 0.023 | 0.1862 | No | ||
87 | EPS8L2 | 2850528 | 9439 | 0.021 | 0.1807 | No | ||
88 | TLX1 | 2630162 | 9731 | 0.016 | 0.1651 | No | ||
89 | ANKRD1 | 4850685 | 9734 | 0.016 | 0.1652 | No | ||
90 | CCND2 | 5340167 | 9898 | 0.014 | 0.1565 | No | ||
91 | TNNI3K | 5890072 | 9915 | 0.013 | 0.1558 | No | ||
92 | POGK | 5290315 | 10117 | 0.010 | 0.1451 | No | ||
93 | SYT2 | 60609 | 10459 | 0.004 | 0.1266 | No | ||
94 | LHX4 | 6940551 | 10500 | 0.004 | 0.1245 | No | ||
95 | BBOX1 | 2030538 2370452 | 10869 | -0.002 | 0.1046 | No | ||
96 | PTPRJ | 4010707 | 10982 | -0.004 | 0.0986 | No | ||
97 | CACNA1E | 840253 | 11094 | -0.006 | 0.0927 | No | ||
98 | VANGL1 | 380162 | 11299 | -0.009 | 0.0817 | No | ||
99 | PRDM16 | 4120541 | 11312 | -0.010 | 0.0812 | No | ||
100 | DR1 | 5860750 | 11705 | -0.017 | 0.0602 | No | ||
101 | SLC1A7 | 1990181 | 11856 | -0.020 | 0.0523 | No | ||
102 | SDCCAG8 | 1780687 | 12332 | -0.030 | 0.0269 | No | ||
103 | KCNIP2 | 60088 1780324 | 12386 | -0.031 | 0.0244 | No | ||
104 | BDNF | 2940128 3520368 | 12660 | -0.038 | 0.0101 | No | ||
105 | LIN28 | 6590672 | 12802 | -0.042 | 0.0029 | No | ||
106 | ATPAF1 | 2470164 | 12856 | -0.044 | 0.0006 | No | ||
107 | TNNT2 | 2450364 | 13114 | -0.052 | -0.0127 | No | ||
108 | KIRREL3 | 2630195 | 13204 | -0.056 | -0.0169 | No | ||
109 | EGR2 | 3800403 | 13438 | -0.065 | -0.0287 | No | ||
110 | FGFR2 | 4670601 5570402 6940377 | 13521 | -0.069 | -0.0324 | No | ||
111 | IFRG15 | 2810538 | 13684 | -0.076 | -0.0402 | No | ||
112 | TIAL1 | 4150048 6510605 | 13803 | -0.082 | -0.0457 | No | ||
113 | KIF1B | 1240494 2370139 4570270 6510102 | 13965 | -0.092 | -0.0533 | No | ||
114 | CHD4 | 5420059 6130338 6380717 | 13979 | -0.093 | -0.0529 | No | ||
115 | MPZ | 1990333 | 14111 | -0.101 | -0.0588 | No | ||
116 | JMJD1C | 940575 2120025 | 14253 | -0.113 | -0.0651 | No | ||
117 | NPPB | 4150722 | 14274 | -0.115 | -0.0648 | No | ||
118 | NOTCH2 | 2570397 | 14467 | -0.131 | -0.0737 | No | ||
119 | CNNM2 | 2650100 | 14598 | -0.145 | -0.0790 | No | ||
120 | KISS1 | 1580398 | 14601 | -0.146 | -0.0774 | No | ||
121 | PRRX1 | 4120193 4480390 | 14623 | -0.149 | -0.0768 | No | ||
122 | HOOK1 | 840450 940390 2480500 2690402 | 14761 | -0.166 | -0.0822 | No | ||
123 | EIF2C1 | 6900551 | 14773 | -0.168 | -0.0809 | No | ||
124 | CDCA3 | 3940397 | 15005 | -0.203 | -0.0910 | No | ||
125 | ANK3 | 1500161 2900435 4210154 6400100 | 15162 | -0.233 | -0.0967 | No | ||
126 | LAMC1 | 4730025 | 15310 | -0.264 | -0.1015 | No | ||
127 | SLC6A9 | 2470520 | 15413 | -0.287 | -0.1037 | No | ||
128 | SHC1 | 2900731 3170504 6520537 | 15499 | -0.308 | -0.1046 | No | ||
129 | MDK | 3840020 | 15615 | -0.341 | -0.1068 | No | ||
130 | VCL | 4120487 | 15804 | -0.405 | -0.1122 | No | ||
131 | MAN1A2 | 5700435 5720114 | 15900 | -0.435 | -0.1122 | No | ||
132 | BCL9L | 6940053 | 16049 | -0.483 | -0.1146 | No | ||
133 | TIMM23 | 60288 7040133 | 16109 | -0.502 | -0.1118 | No | ||
134 | MADD | 6100725 7000088 | 16454 | -0.638 | -0.1229 | No | ||
135 | CHKA | 510324 | 16710 | -0.782 | -0.1275 | No | ||
136 | HMGN2 | 3140091 | 16716 | -0.789 | -0.1185 | No | ||
137 | ITGB1 | 5080156 6270528 | 16739 | -0.801 | -0.1102 | No | ||
138 | OVGP1 | 2630746 2940372 | 16746 | -0.804 | -0.1011 | No | ||
139 | FXYD6 | 3870164 | 16796 | -0.831 | -0.0939 | No | ||
140 | GATA3 | 6130068 | 16831 | -0.855 | -0.0857 | No | ||
141 | LAMB3 | 7100301 | 16910 | -0.903 | -0.0792 | No | ||
142 | CDC14A | 4050132 | 16977 | -0.950 | -0.0716 | No | ||
143 | CRYAB | 4810619 | 17016 | -0.975 | -0.0622 | No | ||
144 | HSPB2 | 1990110 | 17098 | -1.004 | -0.0547 | No | ||
145 | SLC6A13 | 5270152 | 17368 | -1.201 | -0.0551 | No | ||
146 | MTX1 | 5910059 6550181 | 17408 | -1.235 | -0.0427 | No | ||
147 | ATP1B1 | 3130594 | 17741 | -1.572 | -0.0421 | No | ||
148 | CNN3 | 6110020 | 17907 | -1.739 | -0.0305 | No | ||
149 | PPFIA1 | 430176 3610524 | 18508 | -2.837 | -0.0295 | No | ||
150 | ARID1A | 2630022 1690551 4810110 | 18538 | -2.995 | 0.0042 | No |