Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | V$SRF_Q5_01 |
Enrichment Score (ES) | 0.45727745 |
Normalized Enrichment Score (NES) | 1.327297 |
Nominal p-value | 0.02097902 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | MAPKAPK2 | 2850500 | 26 | 3.846 | 0.0403 | Yes | ||
2 | FLNA | 5390193 | 62 | 3.307 | 0.0742 | Yes | ||
3 | PADI2 | 2940092 6420136 | 117 | 2.975 | 0.1036 | Yes | ||
4 | ARPC4 | 2900056 | 199 | 2.722 | 0.1287 | Yes | ||
5 | ASB2 | 4760168 | 220 | 2.652 | 0.1563 | Yes | ||
6 | ARF6 | 3520026 | 355 | 2.362 | 0.1747 | Yes | ||
7 | DUSP10 | 2850673 3360064 | 366 | 2.336 | 0.1994 | Yes | ||
8 | MYL6 | 60563 6100152 | 538 | 2.094 | 0.2129 | Yes | ||
9 | PDLIM7 | 4780136 | 624 | 1.999 | 0.2299 | Yes | ||
10 | MUS81 | 6660184 | 652 | 1.968 | 0.2498 | Yes | ||
11 | BLOC1S1 | 130341 3940717 | 665 | 1.953 | 0.2703 | Yes | ||
12 | EGR1 | 4610347 | 670 | 1.942 | 0.2912 | Yes | ||
13 | CNN2 | 2230433 5270446 | 706 | 1.904 | 0.3099 | Yes | ||
14 | CSRP1 | 2810403 | 725 | 1.880 | 0.3293 | Yes | ||
15 | GRK6 | 1500053 | 899 | 1.715 | 0.3385 | Yes | ||
16 | CDC25B | 6940102 | 1097 | 1.538 | 0.3445 | Yes | ||
17 | UBE2H | 1980142 2970079 | 1161 | 1.491 | 0.3572 | Yes | ||
18 | SERTAD4 | 130593 | 1192 | 1.476 | 0.3716 | Yes | ||
19 | EEF1B2 | 4850400 6130161 | 1198 | 1.472 | 0.3873 | Yes | ||
20 | CKM | 1450524 | 1381 | 1.346 | 0.3920 | Yes | ||
21 | H2AFX | 3520082 | 1412 | 1.332 | 0.4048 | Yes | ||
22 | VASP | 7050500 | 1695 | 1.147 | 0.4020 | Yes | ||
23 | PFN1 | 6130132 | 1701 | 1.144 | 0.4141 | Yes | ||
24 | MRPS21 | 2650008 | 1880 | 1.036 | 0.4157 | Yes | ||
25 | TAZ | 7100193 | 2030 | 0.983 | 0.4183 | Yes | ||
26 | EMILIN2 | 70253 | 2295 | 0.857 | 0.4132 | Yes | ||
27 | RUNDC1 | 2450037 | 2369 | 0.824 | 0.4182 | Yes | ||
28 | RHOJ | 6660176 | 2452 | 0.781 | 0.4222 | Yes | ||
29 | TLE3 | 580040 4730121 | 2456 | 0.780 | 0.4305 | Yes | ||
30 | ANXA6 | 2190014 | 2479 | 0.771 | 0.4377 | Yes | ||
31 | FGFRL1 | 6370047 | 2547 | 0.745 | 0.4421 | Yes | ||
32 | SGK | 1400131 2480056 | 2647 | 0.698 | 0.4443 | Yes | ||
33 | MYADM | 4230132 | 2920 | 0.592 | 0.4360 | Yes | ||
34 | CFL2 | 380239 6200368 | 3035 | 0.551 | 0.4358 | Yes | ||
35 | SLC4A3 | 360603 4730239 6380347 | 3078 | 0.535 | 0.4393 | Yes | ||
36 | JUNB | 4230048 | 3164 | 0.504 | 0.4402 | Yes | ||
37 | TPM2 | 520735 3870390 | 3306 | 0.461 | 0.4375 | Yes | ||
38 | EGR3 | 6940128 | 3418 | 0.434 | 0.4362 | Yes | ||
39 | ACTB | 1660736 2030204 2060215 5050047 | 3426 | 0.433 | 0.4405 | Yes | ||
40 | TAF5L | 5690152 | 3438 | 0.430 | 0.4446 | Yes | ||
41 | COL1A1 | 730020 | 3476 | 0.422 | 0.4472 | Yes | ||
42 | NR2F1 | 4120528 360402 | 3643 | 0.386 | 0.4423 | Yes | ||
43 | FOS | 1850315 | 3645 | 0.386 | 0.4465 | Yes | ||
44 | NPPA | 6550328 | 3668 | 0.382 | 0.4494 | Yes | ||
45 | ELAVL4 | 50735 3360086 5220167 | 3674 | 0.381 | 0.4533 | Yes | ||
46 | DVL3 | 360156 5390075 | 3677 | 0.380 | 0.4573 | Yes | ||
47 | FGF8 | 6350504 | 3853 | 0.346 | 0.4515 | No | ||
48 | MAP1A | 4920576 | 3945 | 0.329 | 0.4502 | No | ||
49 | NRAS | 6900577 | 4037 | 0.314 | 0.4486 | No | ||
50 | MRGPRF | 4780746 | 4364 | 0.264 | 0.4338 | No | ||
51 | GGN | 1410528 4210082 5290170 | 4466 | 0.249 | 0.4311 | No | ||
52 | LRRTM4 | 5910100 | 4504 | 0.243 | 0.4317 | No | ||
53 | SRF | 70139 2320039 | 4578 | 0.235 | 0.4303 | No | ||
54 | FOXE3 | 6900102 | 4598 | 0.234 | 0.4318 | No | ||
55 | PLCB3 | 4670402 | 4661 | 0.227 | 0.4309 | No | ||
56 | ACTG2 | 4780180 | 4745 | 0.217 | 0.4287 | No | ||
57 | CITED2 | 5670114 5130088 | 4784 | 0.213 | 0.4290 | No | ||
58 | PELI2 | 1940364 | 5239 | 0.170 | 0.4062 | No | ||
59 | TGFB1I1 | 2060288 6550450 | 5331 | 0.163 | 0.4030 | No | ||
60 | PCDH7 | 450398 4150040 | 5391 | 0.158 | 0.4015 | No | ||
61 | PPAP2B | 3190397 4730280 | 5410 | 0.156 | 0.4023 | No | ||
62 | FOXP2 | 3520561 4150372 4760524 | 5437 | 0.155 | 0.4025 | No | ||
63 | WNT3 | 2360685 | 5468 | 0.153 | 0.4026 | No | ||
64 | STAT5B | 6200026 | 5493 | 0.151 | 0.4029 | No | ||
65 | ITGB1BP2 | 6200129 | 5536 | 0.148 | 0.4022 | No | ||
66 | MYLK | 4010600 7000364 | 5581 | 0.144 | 0.4014 | No | ||
67 | SRD5A2 | 6840433 | 5634 | 0.141 | 0.4001 | No | ||
68 | RSU1 | 4850372 | 5684 | 0.138 | 0.3989 | No | ||
69 | COL23A1 | 2030358 | 5697 | 0.137 | 0.3998 | No | ||
70 | DLL1 | 1770377 | 5744 | 0.134 | 0.3987 | No | ||
71 | RIMS1 | 5670022 | 6239 | 0.107 | 0.3731 | No | ||
72 | HOXB5 | 2900538 | 6359 | 0.101 | 0.3678 | No | ||
73 | TADA3L | 4210070 5720088 6660333 | 6380 | 0.100 | 0.3678 | No | ||
74 | PPARG | 1990168 2680603 6130632 | 6395 | 0.100 | 0.3681 | No | ||
75 | ATF3 | 1940546 | 6450 | 0.097 | 0.3662 | No | ||
76 | CA3 | 870687 5890390 | 6457 | 0.097 | 0.3669 | No | ||
77 | CHST8 | 1940050 | 6596 | 0.091 | 0.3604 | No | ||
78 | CASQ1 | 6290035 7000707 | 6627 | 0.090 | 0.3598 | No | ||
79 | FLNC | 2360048 5050270 | 6651 | 0.089 | 0.3595 | No | ||
80 | PODN | 3710068 | 6717 | 0.087 | 0.3569 | No | ||
81 | CACNA1B | 1740010 5360593 | 6726 | 0.086 | 0.3574 | No | ||
82 | LRRFIP1 | 870259 1050204 2760377 | 6803 | 0.083 | 0.3542 | No | ||
83 | RASSF2 | 2480079 5720546 | 6822 | 0.083 | 0.3541 | No | ||
84 | PLN | 3940132 | 6832 | 0.083 | 0.3545 | No | ||
85 | MLLT7 | 4480707 | 7021 | 0.076 | 0.3452 | No | ||
86 | RAI2 | 6770333 | 7132 | 0.072 | 0.3400 | No | ||
87 | CALD1 | 1770129 1940397 | 7213 | 0.070 | 0.3364 | No | ||
88 | ABR | 610079 1170609 3610195 5670050 | 7285 | 0.068 | 0.3333 | No | ||
89 | TANK | 1090020 2060458 2370400 | 7540 | 0.061 | 0.3202 | No | ||
90 | DSTN | 3140592 | 7545 | 0.061 | 0.3206 | No | ||
91 | IER2 | 2030008 | 7641 | 0.058 | 0.3161 | No | ||
92 | HOXC5 | 1580017 | 7717 | 0.056 | 0.3126 | No | ||
93 | BNC2 | 4810603 | 7719 | 0.056 | 0.3132 | No | ||
94 | NPAS2 | 770670 | 7791 | 0.054 | 0.3099 | No | ||
95 | CNN1 | 510707 | 7875 | 0.052 | 0.3060 | No | ||
96 | CALN1 | 3610722 | 7896 | 0.052 | 0.3055 | No | ||
97 | KCNA1 | 2030594 | 7898 | 0.052 | 0.3060 | No | ||
98 | NKX2-2 | 4150731 | 7960 | 0.050 | 0.3032 | No | ||
99 | CXCL5 | 6370333 | 7983 | 0.050 | 0.3026 | No | ||
100 | LPP | 1660541 | 8155 | 0.046 | 0.2938 | No | ||
101 | NRXN3 | 1400546 3360471 | 8373 | 0.041 | 0.2825 | No | ||
102 | HOXC4 | 1940193 | 8546 | 0.038 | 0.2735 | No | ||
103 | ABCA1 | 6290156 | 8659 | 0.035 | 0.2678 | No | ||
104 | ASPA | 3290400 | 9038 | 0.028 | 0.2477 | No | ||
105 | TRDN | 1580411 | 9195 | 0.025 | 0.2395 | No | ||
106 | ACTA1 | 840538 | 9331 | 0.023 | 0.2324 | No | ||
107 | NFATC4 | 2470735 | 9458 | 0.021 | 0.2258 | No | ||
108 | MYO1E | 3140504 | 9494 | 0.020 | 0.2241 | No | ||
109 | DIXDC1 | 6980435 | 10047 | 0.011 | 0.1943 | No | ||
110 | TAGLN | 6660280 | 10085 | 0.010 | 0.1924 | No | ||
111 | MYL9 | 4210750 7050138 | 10173 | 0.009 | 0.1878 | No | ||
112 | HOXD10 | 6100039 | 10374 | 0.006 | 0.1770 | No | ||
113 | MYH11 | 7100273 | 10648 | 0.001 | 0.1622 | No | ||
114 | KCNK3 | 2690372 | 11147 | -0.007 | 0.1353 | No | ||
115 | IL17B | 6940711 | 11182 | -0.008 | 0.1335 | No | ||
116 | SLC2A4 | 540441 | 11569 | -0.014 | 0.1128 | No | ||
117 | FGF7 | 5390484 | 11593 | -0.015 | 0.1117 | No | ||
118 | CRH | 3710301 | 11643 | -0.016 | 0.1092 | No | ||
119 | NPR3 | 1580239 | 11950 | -0.021 | 0.0928 | No | ||
120 | MITF | 380056 | 12042 | -0.024 | 0.0881 | No | ||
121 | THRAP1 | 2470121 | 12182 | -0.027 | 0.0809 | No | ||
122 | ADAMTSL1 | 2970092 | 12428 | -0.032 | 0.0680 | No | ||
123 | RARB | 430139 1410138 | 12614 | -0.037 | 0.0583 | No | ||
124 | PRKAB2 | 6980300 | 12629 | -0.037 | 0.0580 | No | ||
125 | ACTR3 | 1400497 | 12632 | -0.037 | 0.0583 | No | ||
126 | ITGB6 | 2810068 4570332 | 12671 | -0.038 | 0.0566 | No | ||
127 | THBS1 | 4560494 430288 | 12677 | -0.039 | 0.0568 | No | ||
128 | STARD13 | 540722 | 12837 | -0.043 | 0.0486 | No | ||
129 | NR2F2 | 3170609 3310577 | 12988 | -0.048 | 0.0410 | No | ||
130 | FOSB | 1940142 | 13018 | -0.049 | 0.0400 | No | ||
131 | TRIM46 | 3520609 4590010 | 13084 | -0.051 | 0.0370 | No | ||
132 | GPR20 | 6620601 | 13118 | -0.052 | 0.0358 | No | ||
133 | SDPR | 3360292 | 13176 | -0.055 | 0.0333 | No | ||
134 | TNMD | 3060520 | 13303 | -0.060 | 0.0271 | No | ||
135 | EGR2 | 3800403 | 13438 | -0.065 | 0.0205 | No | ||
136 | EFHD1 | 4070358 | 13449 | -0.065 | 0.0207 | No | ||
137 | OTX1 | 2510215 | 13778 | -0.081 | 0.0038 | No | ||
138 | FGF17 | 3130022 | 14165 | -0.106 | -0.0160 | No | ||
139 | RERE | 3940279 | 14292 | -0.117 | -0.0216 | No | ||
140 | MID1 | 4070114 4760458 | 14377 | -0.124 | -0.0248 | No | ||
141 | TRIM3 | 5570156 | 14454 | -0.130 | -0.0275 | No | ||
142 | CDKN1B | 3800025 6450044 | 14572 | -0.142 | -0.0323 | No | ||
143 | MAP2K6 | 1230056 2940204 | 14593 | -0.145 | -0.0318 | No | ||
144 | ASXL2 | 130670 | 15015 | -0.204 | -0.0524 | No | ||
145 | MYL7 | 2480541 | 15019 | -0.205 | -0.0504 | No | ||
146 | PICALM | 1940280 | 15187 | -0.238 | -0.0568 | No | ||
147 | GADD45G | 2510142 | 15193 | -0.240 | -0.0545 | No | ||
148 | CORO1C | 4570397 | 15368 | -0.278 | -0.0609 | No | ||
149 | PHF12 | 870400 3130687 | 15491 | -0.306 | -0.0642 | No | ||
150 | VCL | 4120487 | 15804 | -0.405 | -0.0767 | No | ||
151 | TIMP3 | 1450504 1980270 | 15927 | -0.443 | -0.0786 | No | ||
152 | LCP1 | 4280397 | 16029 | -0.475 | -0.0789 | No | ||
153 | CHD2 | 4070039 | 16070 | -0.490 | -0.0757 | No | ||
154 | SLC16A6 | 1690156 | 16145 | -0.516 | -0.0742 | No | ||
155 | PPP1R12A | 4070066 4590162 | 16212 | -0.543 | -0.0719 | No | ||
156 | KRTCAP2 | 5220040 | 16244 | -0.553 | -0.0675 | No | ||
157 | SVIL | 2450347 4050735 4070576 4120706 5390161 5860142 6520278 7100397 | 16281 | -0.569 | -0.0633 | No | ||
158 | CSDA | 2470092 3060053 4780056 | 16284 | -0.572 | -0.0572 | No | ||
159 | FOXP1 | 6510433 | 16376 | -0.605 | -0.0556 | No | ||
160 | ERBB2IP | 580253 1090672 | 16411 | -0.621 | -0.0507 | No | ||
161 | SLC25A4 | 2360519 | 16458 | -0.642 | -0.0463 | No | ||
162 | DGKG | 1770025 | 16462 | -0.643 | -0.0395 | No | ||
163 | MBNL1 | 2640762 7100048 | 16585 | -0.700 | -0.0385 | No | ||
164 | SCOC | 610048 2230053 | 16671 | -0.761 | -0.0348 | No | ||
165 | LDB1 | 5270601 | 16834 | -0.855 | -0.0343 | No | ||
166 | EML4 | 5700373 | 16965 | -0.941 | -0.0312 | No | ||
167 | CFL1 | 2340735 | 16966 | -0.941 | -0.0210 | No | ||
168 | TPM3 | 670600 3170296 5670167 6650471 | 17068 | -0.998 | -0.0157 | No | ||
169 | MAPK14 | 5290731 | 17315 | -1.150 | -0.0165 | No | ||
170 | KCNH2 | 1170451 | 17472 | -1.287 | -0.0110 | No | ||
171 | ATF4 | 730441 1740195 | 17764 | -1.594 | -0.0095 | No | ||
172 | HOXB4 | 540131 | 17850 | -1.681 | 0.0041 | No | ||
173 | RBBP7 | 430113 450450 2370309 | 17868 | -1.701 | 0.0216 | No | ||
174 | H3F3A | 2900086 | 17914 | -1.745 | 0.0381 | No |