Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | V$SRF_Q4 |
Enrichment Score (ES) | 0.41942316 |
Normalized Enrichment Score (NES) | 1.2298592 |
Nominal p-value | 0.062228654 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | MAPKAPK2 | 2850500 | 26 | 3.846 | 0.0425 | Yes | ||
2 | FLNA | 5390193 | 62 | 3.307 | 0.0783 | Yes | ||
3 | PADI2 | 2940092 6420136 | 117 | 2.975 | 0.1093 | Yes | ||
4 | ARPC4 | 2900056 | 199 | 2.722 | 0.1359 | Yes | ||
5 | AGRP | 1990082 | 438 | 2.207 | 0.1482 | Yes | ||
6 | MYL6 | 60563 6100152 | 538 | 2.094 | 0.1667 | Yes | ||
7 | MUS81 | 6660184 | 652 | 1.968 | 0.1830 | Yes | ||
8 | BLOC1S1 | 130341 3940717 | 665 | 1.953 | 0.2047 | Yes | ||
9 | EGR1 | 4610347 | 670 | 1.942 | 0.2266 | Yes | ||
10 | CSRP1 | 2810403 | 725 | 1.880 | 0.2451 | Yes | ||
11 | NPM3 | 3610300 | 865 | 1.742 | 0.2575 | Yes | ||
12 | TPM1 | 130673 | 883 | 1.728 | 0.2762 | Yes | ||
13 | GRK6 | 1500053 | 899 | 1.715 | 0.2950 | Yes | ||
14 | SERTAD4 | 130593 | 1192 | 1.476 | 0.2960 | Yes | ||
15 | EEF1B2 | 4850400 6130161 | 1198 | 1.472 | 0.3125 | Yes | ||
16 | CKM | 1450524 | 1381 | 1.346 | 0.3180 | Yes | ||
17 | H2AFX | 3520082 | 1412 | 1.332 | 0.3316 | Yes | ||
18 | ESRRA | 6550242 | 1522 | 1.257 | 0.3400 | Yes | ||
19 | SLC35A2 | 6770156 | 1687 | 1.153 | 0.3442 | Yes | ||
20 | VASP | 7050500 | 1695 | 1.147 | 0.3569 | Yes | ||
21 | PFN1 | 6130132 | 1701 | 1.144 | 0.3697 | Yes | ||
22 | TAZ | 7100193 | 2030 | 0.983 | 0.3631 | Yes | ||
23 | EMILIN2 | 70253 | 2295 | 0.857 | 0.3586 | Yes | ||
24 | RUNDC1 | 2450037 | 2369 | 0.824 | 0.3640 | Yes | ||
25 | RHOJ | 6660176 | 2452 | 0.781 | 0.3685 | Yes | ||
26 | TLE3 | 580040 4730121 | 2456 | 0.780 | 0.3772 | Yes | ||
27 | ANXA6 | 2190014 | 2479 | 0.771 | 0.3848 | Yes | ||
28 | FGFRL1 | 6370047 | 2547 | 0.745 | 0.3897 | Yes | ||
29 | SERPINH1 | 6130014 | 2555 | 0.742 | 0.3978 | Yes | ||
30 | SGK | 1400131 2480056 | 2647 | 0.698 | 0.4008 | Yes | ||
31 | IHPK1 | 1340053 | 2727 | 0.661 | 0.4041 | Yes | ||
32 | CFL2 | 380239 6200368 | 3035 | 0.551 | 0.3937 | Yes | ||
33 | POU3F4 | 870274 | 3076 | 0.535 | 0.3977 | Yes | ||
34 | SLC4A3 | 360603 4730239 6380347 | 3078 | 0.535 | 0.4037 | Yes | ||
35 | JUNB | 4230048 | 3164 | 0.504 | 0.4049 | Yes | ||
36 | TPM2 | 520735 3870390 | 3306 | 0.461 | 0.4025 | Yes | ||
37 | EGR3 | 6940128 | 3418 | 0.434 | 0.4014 | Yes | ||
38 | ACTB | 1660736 2030204 2060215 5050047 | 3426 | 0.433 | 0.4060 | Yes | ||
39 | TAF5L | 5690152 | 3438 | 0.430 | 0.4103 | Yes | ||
40 | NR2F1 | 4120528 360402 | 3643 | 0.386 | 0.4036 | Yes | ||
41 | FOS | 1850315 | 3645 | 0.386 | 0.4080 | Yes | ||
42 | NPPA | 6550328 | 3668 | 0.382 | 0.4111 | Yes | ||
43 | ELAVL4 | 50735 3360086 5220167 | 3674 | 0.381 | 0.4152 | Yes | ||
44 | DVL3 | 360156 5390075 | 3677 | 0.380 | 0.4194 | Yes | ||
45 | FGF8 | 6350504 | 3853 | 0.346 | 0.4139 | No | ||
46 | MAP1A | 4920576 | 3945 | 0.329 | 0.4127 | No | ||
47 | DUSP6 | 5910286 7100070 | 3988 | 0.323 | 0.4141 | No | ||
48 | CX3CL1 | 3990707 | 4299 | 0.272 | 0.4004 | No | ||
49 | MRGPRF | 4780746 | 4364 | 0.264 | 0.3999 | No | ||
50 | LRRTM4 | 5910100 | 4504 | 0.243 | 0.3952 | No | ||
51 | SRF | 70139 2320039 | 4578 | 0.235 | 0.3939 | No | ||
52 | FOXE3 | 6900102 | 4598 | 0.234 | 0.3955 | No | ||
53 | PLCB3 | 4670402 | 4661 | 0.227 | 0.3948 | No | ||
54 | ASPH | 360722 1940039 2100066 2340121 2650113 2810064 2970008 3140040 3800750 4210014 4280133 4590035 4760433 6370671 6940338 | 4680 | 0.224 | 0.3963 | No | ||
55 | ACTG2 | 4780180 | 4745 | 0.217 | 0.3953 | No | ||
56 | CITED2 | 5670114 5130088 | 4784 | 0.213 | 0.3957 | No | ||
57 | TGFB1I1 | 2060288 6550450 | 5331 | 0.163 | 0.3680 | No | ||
58 | PPAP2B | 3190397 4730280 | 5410 | 0.156 | 0.3655 | No | ||
59 | FOXP2 | 3520561 4150372 4760524 | 5437 | 0.155 | 0.3659 | No | ||
60 | STAT5B | 6200026 | 5493 | 0.151 | 0.3646 | No | ||
61 | JPH2 | 940041 5860026 | 5508 | 0.150 | 0.3656 | No | ||
62 | ITGB1BP2 | 6200129 | 5536 | 0.148 | 0.3658 | No | ||
63 | MYLK | 4010600 7000364 | 5581 | 0.144 | 0.3651 | No | ||
64 | SRD5A2 | 6840433 | 5634 | 0.141 | 0.3638 | No | ||
65 | RSU1 | 4850372 | 5684 | 0.138 | 0.3628 | No | ||
66 | COL23A1 | 2030358 | 5697 | 0.137 | 0.3637 | No | ||
67 | CTGF | 4540577 | 5729 | 0.135 | 0.3635 | No | ||
68 | DLL1 | 1770377 | 5744 | 0.134 | 0.3643 | No | ||
69 | HOXA3 | 3610632 6020358 | 5970 | 0.121 | 0.3535 | No | ||
70 | DMD | 1740041 3990332 | 6236 | 0.107 | 0.3403 | No | ||
71 | RIMS1 | 5670022 | 6239 | 0.107 | 0.3415 | No | ||
72 | HOXB5 | 2900538 | 6359 | 0.101 | 0.3362 | No | ||
73 | TADA3L | 4210070 5720088 6660333 | 6380 | 0.100 | 0.3362 | No | ||
74 | PPARG | 1990168 2680603 6130632 | 6395 | 0.100 | 0.3366 | No | ||
75 | MYO1B | 770372 | 6464 | 0.097 | 0.3340 | No | ||
76 | TMOD1 | 3850100 | 6497 | 0.095 | 0.3334 | No | ||
77 | PODN | 3710068 | 6717 | 0.087 | 0.3225 | No | ||
78 | CACNA1B | 1740010 5360593 | 6726 | 0.086 | 0.3230 | No | ||
79 | RASSF2 | 2480079 5720546 | 6822 | 0.083 | 0.3188 | No | ||
80 | TNNC1 | 1990575 | 6971 | 0.077 | 0.3117 | No | ||
81 | CALD1 | 1770129 1940397 | 7213 | 0.070 | 0.2994 | No | ||
82 | ABR | 610079 1170609 3610195 5670050 | 7285 | 0.068 | 0.2963 | No | ||
83 | TANK | 1090020 2060458 2370400 | 7540 | 0.061 | 0.2833 | No | ||
84 | DSTN | 3140592 | 7545 | 0.061 | 0.2837 | No | ||
85 | IER2 | 2030008 | 7641 | 0.058 | 0.2793 | No | ||
86 | HOXC5 | 1580017 | 7717 | 0.056 | 0.2758 | No | ||
87 | BNC2 | 4810603 | 7719 | 0.056 | 0.2764 | No | ||
88 | NPAS2 | 770670 | 7791 | 0.054 | 0.2732 | No | ||
89 | NR4A1 | 6290161 | 7795 | 0.054 | 0.2736 | No | ||
90 | CNN1 | 510707 | 7875 | 0.052 | 0.2700 | No | ||
91 | CALN1 | 3610722 | 7896 | 0.052 | 0.2695 | No | ||
92 | KCNA1 | 2030594 | 7898 | 0.052 | 0.2700 | No | ||
93 | NKX2-2 | 4150731 | 7960 | 0.050 | 0.2673 | No | ||
94 | LPP | 1660541 | 8155 | 0.046 | 0.2573 | No | ||
95 | ASPA | 3290400 | 9038 | 0.028 | 0.2098 | No | ||
96 | ACTA1 | 840538 | 9331 | 0.023 | 0.1942 | No | ||
97 | EGR4 | 3120750 | 9432 | 0.021 | 0.1890 | No | ||
98 | MYO1E | 3140504 | 9494 | 0.020 | 0.1860 | No | ||
99 | DIXDC1 | 6980435 | 10047 | 0.011 | 0.1562 | No | ||
100 | TAGLN | 6660280 | 10085 | 0.010 | 0.1543 | No | ||
101 | GAB2 | 1410280 2340520 4280040 | 10087 | 0.010 | 0.1543 | No | ||
102 | HOXA5 | 6840026 | 10171 | 0.009 | 0.1499 | No | ||
103 | MYL9 | 4210750 7050138 | 10173 | 0.009 | 0.1500 | No | ||
104 | KCNMB1 | 4760139 | 10310 | 0.006 | 0.1427 | No | ||
105 | MSX1 | 2650309 | 10361 | 0.006 | 0.1400 | No | ||
106 | RASD2 | 3360010 | 10371 | 0.006 | 0.1396 | No | ||
107 | HOXD10 | 6100039 | 10374 | 0.006 | 0.1396 | No | ||
108 | MYH11 | 7100273 | 10648 | 0.001 | 0.1248 | No | ||
109 | KCNK3 | 2690372 | 11147 | -0.007 | 0.0979 | No | ||
110 | IL17B | 6940711 | 11182 | -0.008 | 0.0961 | No | ||
111 | NLGN3 | 2650463 | 11241 | -0.009 | 0.0931 | No | ||
112 | FST | 1110600 | 11433 | -0.012 | 0.0829 | No | ||
113 | NCOA6 | 1780333 6450110 | 11461 | -0.012 | 0.0815 | No | ||
114 | CRH | 3710301 | 11643 | -0.016 | 0.0719 | No | ||
115 | SH3BGR | 840400 | 11832 | -0.019 | 0.0619 | No | ||
116 | NPR3 | 1580239 | 11950 | -0.021 | 0.0558 | No | ||
117 | EDN1 | 1770047 | 12024 | -0.023 | 0.0521 | No | ||
118 | MYL1 | 2450707 | 12085 | -0.025 | 0.0492 | No | ||
119 | INSM1 | 3450671 | 12097 | -0.025 | 0.0488 | No | ||
120 | THRAP1 | 2470121 | 12182 | -0.027 | 0.0446 | No | ||
121 | ADAMTSL1 | 2970092 | 12428 | -0.032 | 0.0317 | No | ||
122 | RARB | 430139 1410138 | 12614 | -0.037 | 0.0221 | No | ||
123 | THBS1 | 4560494 430288 | 12677 | -0.039 | 0.0192 | No | ||
124 | ATRX | 2340039 3610132 4210373 | 12753 | -0.041 | 0.0156 | No | ||
125 | NR2F2 | 3170609 3310577 | 12988 | -0.048 | 0.0034 | No | ||
126 | FOSB | 1940142 | 13018 | -0.049 | 0.0024 | No | ||
127 | TRIM46 | 3520609 4590010 | 13084 | -0.051 | -0.0005 | No | ||
128 | GPR20 | 6620601 | 13118 | -0.052 | -0.0017 | No | ||
129 | SDPR | 3360292 | 13176 | -0.055 | -0.0042 | No | ||
130 | TNMD | 3060520 | 13303 | -0.060 | -0.0103 | No | ||
131 | EGR2 | 3800403 | 13438 | -0.065 | -0.0169 | No | ||
132 | EFHD1 | 4070358 | 13449 | -0.065 | -0.0167 | No | ||
133 | FGF17 | 3130022 | 14165 | -0.106 | -0.0542 | No | ||
134 | RERE | 3940279 | 14292 | -0.117 | -0.0597 | No | ||
135 | MID1 | 4070114 4760458 | 14377 | -0.124 | -0.0628 | No | ||
136 | CDKN1B | 3800025 6450044 | 14572 | -0.142 | -0.0717 | No | ||
137 | MAP2K6 | 1230056 2940204 | 14593 | -0.145 | -0.0712 | No | ||
138 | ROCK2 | 1780035 5720025 | 14976 | -0.199 | -0.0896 | No | ||
139 | ARHGEF17 | 2060008 | 14984 | -0.200 | -0.0877 | No | ||
140 | MYL7 | 2480541 | 15019 | -0.205 | -0.0872 | No | ||
141 | SRP54 | 2970605 | 15127 | -0.227 | -0.0904 | No | ||
142 | DUSP2 | 2370184 | 15174 | -0.235 | -0.0903 | No | ||
143 | GADD45G | 2510142 | 15193 | -0.240 | -0.0885 | No | ||
144 | PHF12 | 870400 3130687 | 15491 | -0.306 | -0.1011 | No | ||
145 | ELF4 | 4850193 | 15581 | -0.330 | -0.1022 | No | ||
146 | VCL | 4120487 | 15804 | -0.405 | -0.1096 | No | ||
147 | STAG2 | 4540132 | 16056 | -0.485 | -0.1177 | No | ||
148 | CHD2 | 4070039 | 16070 | -0.490 | -0.1128 | No | ||
149 | PPP1R12A | 4070066 4590162 | 16212 | -0.543 | -0.1142 | No | ||
150 | KRTCAP2 | 5220040 | 16244 | -0.553 | -0.1096 | No | ||
151 | SVIL | 2450347 4050735 4070576 4120706 5390161 5860142 6520278 7100397 | 16281 | -0.569 | -0.1051 | No | ||
152 | CSDA | 2470092 3060053 4780056 | 16284 | -0.572 | -0.0987 | No | ||
153 | FOXP1 | 6510433 | 16376 | -0.605 | -0.0967 | No | ||
154 | SORT1 | 1850242 2320632 3870537 | 16382 | -0.608 | -0.0900 | No | ||
155 | ERBB2IP | 580253 1090672 | 16411 | -0.621 | -0.0845 | No | ||
156 | SLC25A4 | 2360519 | 16458 | -0.642 | -0.0796 | No | ||
157 | DGKG | 1770025 | 16462 | -0.643 | -0.0725 | No | ||
158 | MBNL1 | 2640762 7100048 | 16585 | -0.700 | -0.0711 | No | ||
159 | SCOC | 610048 2230053 | 16671 | -0.761 | -0.0670 | No | ||
160 | TBL1X | 6400524 | 16839 | -0.858 | -0.0663 | No | ||
161 | EML4 | 5700373 | 16965 | -0.941 | -0.0623 | No | ||
162 | CFL1 | 2340735 | 16966 | -0.941 | -0.0516 | No | ||
163 | MMP14 | 670079 | 16996 | -0.964 | -0.0422 | No | ||
164 | TPM3 | 670600 3170296 5670167 6650471 | 17068 | -0.998 | -0.0347 | No | ||
165 | MAPK14 | 5290731 | 17315 | -1.150 | -0.0349 | No | ||
166 | AKAP12 | 1450739 | 17716 | -1.545 | -0.0389 | No | ||
167 | HOXB4 | 540131 | 17850 | -1.681 | -0.0270 | No | ||
168 | RBBP7 | 430113 450450 2370309 | 17868 | -1.701 | -0.0085 | No | ||
169 | MCL1 | 1660672 | 18610 | -4.296 | 0.0003 | No |