Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | V$SRF_C |
Enrichment Score (ES) | 0.43086147 |
Normalized Enrichment Score (NES) | 1.26069 |
Nominal p-value | 0.05124451 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | FLNA | 5390193 | 62 | 3.307 | 0.0361 | Yes | ||
2 | PADI2 | 2940092 6420136 | 117 | 2.975 | 0.0688 | Yes | ||
3 | ARPC4 | 2900056 | 199 | 2.722 | 0.0969 | Yes | ||
4 | ASB2 | 4760168 | 220 | 2.652 | 0.1275 | Yes | ||
5 | PNKP | 4610685 5720605 | 363 | 2.346 | 0.1478 | Yes | ||
6 | DUSP10 | 2850673 3360064 | 366 | 2.336 | 0.1756 | Yes | ||
7 | MYL6 | 60563 6100152 | 538 | 2.094 | 0.1914 | Yes | ||
8 | PDLIM7 | 4780136 | 624 | 1.999 | 0.2107 | Yes | ||
9 | MUS81 | 6660184 | 652 | 1.968 | 0.2327 | Yes | ||
10 | EGR1 | 4610347 | 670 | 1.942 | 0.2550 | Yes | ||
11 | CNN2 | 2230433 5270446 | 706 | 1.904 | 0.2758 | Yes | ||
12 | GRK6 | 1500053 | 899 | 1.715 | 0.2859 | Yes | ||
13 | KCTD15 | 2810735 | 1116 | 1.526 | 0.2925 | Yes | ||
14 | CKM | 1450524 | 1381 | 1.346 | 0.2942 | Yes | ||
15 | DAPK3 | 4590121 | 1386 | 1.344 | 0.3101 | Yes | ||
16 | FHL2 | 1400008 | 1663 | 1.165 | 0.3090 | Yes | ||
17 | PFN1 | 6130132 | 1701 | 1.144 | 0.3207 | Yes | ||
18 | CAP1 | 2650278 | 1715 | 1.136 | 0.3336 | Yes | ||
19 | TUFT1 | 540047 2370010 | 1860 | 1.046 | 0.3383 | Yes | ||
20 | RGS3 | 60670 540736 1340180 1500369 3390735 4010131 4610402 6380114 | 1960 | 1.004 | 0.3449 | Yes | ||
21 | TAZ | 7100193 | 2030 | 0.983 | 0.3529 | Yes | ||
22 | TOP1 | 770471 4060632 6650324 | 2058 | 0.968 | 0.3630 | Yes | ||
23 | ARHGAP1 | 2810010 5270064 | 2242 | 0.884 | 0.3637 | Yes | ||
24 | EMILIN2 | 70253 | 2295 | 0.857 | 0.3711 | Yes | ||
25 | RUNDC1 | 2450037 | 2369 | 0.824 | 0.3770 | Yes | ||
26 | RHOJ | 6660176 | 2452 | 0.781 | 0.3818 | Yes | ||
27 | TLE3 | 580040 4730121 | 2456 | 0.780 | 0.3910 | Yes | ||
28 | PDLIM4 | 3990358 | 2478 | 0.772 | 0.3991 | Yes | ||
29 | ANXA6 | 2190014 | 2479 | 0.771 | 0.4083 | Yes | ||
30 | FGFRL1 | 6370047 | 2547 | 0.745 | 0.4136 | Yes | ||
31 | SIPA1 | 5220687 | 2672 | 0.687 | 0.4151 | Yes | ||
32 | CYR61 | 1240408 5290026 4120452 6550008 | 2750 | 0.650 | 0.4187 | Yes | ||
33 | MRVI1 | 4810338 4850601 5900441 | 2974 | 0.573 | 0.4134 | Yes | ||
34 | CFL2 | 380239 6200368 | 3035 | 0.551 | 0.4168 | Yes | ||
35 | POU3F4 | 870274 | 3076 | 0.535 | 0.4210 | Yes | ||
36 | JUNB | 4230048 | 3164 | 0.504 | 0.4223 | Yes | ||
37 | MCAM | 5130270 6620577 | 3406 | 0.437 | 0.4144 | Yes | ||
38 | EGR3 | 6940128 | 3418 | 0.434 | 0.4190 | Yes | ||
39 | ACTB | 1660736 2030204 2060215 5050047 | 3426 | 0.433 | 0.4238 | Yes | ||
40 | NR2F1 | 4120528 360402 | 3643 | 0.386 | 0.4167 | Yes | ||
41 | FOS | 1850315 | 3645 | 0.386 | 0.4213 | Yes | ||
42 | ELAVL4 | 50735 3360086 5220167 | 3674 | 0.381 | 0.4243 | Yes | ||
43 | DVL3 | 360156 5390075 | 3677 | 0.380 | 0.4288 | Yes | ||
44 | TITF1 | 3390554 4540292 | 3844 | 0.346 | 0.4239 | Yes | ||
45 | MATR3 | 1940170 5340278 | 3846 | 0.346 | 0.4280 | Yes | ||
46 | MAP1A | 4920576 | 3945 | 0.329 | 0.4266 | Yes | ||
47 | DUSP6 | 5910286 7100070 | 3988 | 0.323 | 0.4282 | Yes | ||
48 | COL1A2 | 380364 | 4010 | 0.319 | 0.4309 | Yes | ||
49 | LRP5 | 2100397 3170484 | 4138 | 0.295 | 0.4275 | No | ||
50 | NKX6-2 | 2450332 3120333 | 4350 | 0.266 | 0.4193 | No | ||
51 | MRGPRF | 4780746 | 4364 | 0.264 | 0.4217 | No | ||
52 | GFPT2 | 2370129 | 4370 | 0.263 | 0.4246 | No | ||
53 | LMCD1 | 1740484 2190097 | 4392 | 0.260 | 0.4265 | No | ||
54 | GGN | 1410528 4210082 5290170 | 4466 | 0.249 | 0.4256 | No | ||
55 | SRF | 70139 2320039 | 4578 | 0.235 | 0.4224 | No | ||
56 | FOXE3 | 6900102 | 4598 | 0.234 | 0.4241 | No | ||
57 | ACVR1 | 6840671 | 4652 | 0.228 | 0.4240 | No | ||
58 | PLCB3 | 4670402 | 4661 | 0.227 | 0.4263 | No | ||
59 | ACTG2 | 4780180 | 4745 | 0.217 | 0.4243 | No | ||
60 | MYO18B | 7100670 | 5266 | 0.168 | 0.3982 | No | ||
61 | SYNCRIP | 1690195 3140113 4670279 | 5278 | 0.167 | 0.3996 | No | ||
62 | TGFB1I1 | 2060288 6550450 | 5331 | 0.163 | 0.3987 | No | ||
63 | FOXP2 | 3520561 4150372 4760524 | 5437 | 0.155 | 0.3949 | No | ||
64 | STAT5B | 6200026 | 5493 | 0.151 | 0.3937 | No | ||
65 | JPH2 | 940041 5860026 | 5508 | 0.150 | 0.3947 | No | ||
66 | ITGB1BP2 | 6200129 | 5536 | 0.148 | 0.3950 | No | ||
67 | MYLK | 4010600 7000364 | 5581 | 0.144 | 0.3944 | No | ||
68 | SRD5A2 | 6840433 | 5634 | 0.141 | 0.3932 | No | ||
69 | RSU1 | 4850372 | 5684 | 0.138 | 0.3922 | No | ||
70 | DLL1 | 1770377 | 5744 | 0.134 | 0.3906 | No | ||
71 | HOXA3 | 3610632 6020358 | 5970 | 0.121 | 0.3799 | No | ||
72 | DMD | 1740041 3990332 | 6236 | 0.107 | 0.3668 | No | ||
73 | HOXB5 | 2900538 | 6359 | 0.101 | 0.3614 | No | ||
74 | TADA3L | 4210070 5720088 6660333 | 6380 | 0.100 | 0.3615 | No | ||
75 | CA3 | 870687 5890390 | 6457 | 0.097 | 0.3586 | No | ||
76 | MYO1B | 770372 | 6464 | 0.097 | 0.3594 | No | ||
77 | CACNA1B | 1740010 5360593 | 6726 | 0.086 | 0.3463 | No | ||
78 | RASSF2 | 2480079 5720546 | 6822 | 0.083 | 0.3421 | No | ||
79 | PLN | 3940132 | 6832 | 0.083 | 0.3426 | No | ||
80 | TNNC1 | 1990575 | 6971 | 0.077 | 0.3361 | No | ||
81 | ITGA7 | 1230739 | 7104 | 0.073 | 0.3298 | No | ||
82 | CALD1 | 1770129 1940397 | 7213 | 0.070 | 0.3248 | No | ||
83 | TANK | 1090020 2060458 2370400 | 7540 | 0.061 | 0.3078 | No | ||
84 | DSTN | 3140592 | 7545 | 0.061 | 0.3084 | No | ||
85 | SSH3 | 6290110 6650497 | 7567 | 0.060 | 0.3079 | No | ||
86 | IER2 | 2030008 | 7641 | 0.058 | 0.3047 | No | ||
87 | NPAS2 | 770670 | 7791 | 0.054 | 0.2972 | No | ||
88 | NR4A1 | 6290161 | 7795 | 0.054 | 0.2977 | No | ||
89 | CNN1 | 510707 | 7875 | 0.052 | 0.2941 | No | ||
90 | NKX2-2 | 4150731 | 7960 | 0.050 | 0.2901 | No | ||
91 | LPP | 1660541 | 8155 | 0.046 | 0.2802 | No | ||
92 | MEIS1 | 1400575 | 8223 | 0.044 | 0.2771 | No | ||
93 | FOSL1 | 430021 | 8986 | 0.029 | 0.2361 | No | ||
94 | ASPA | 3290400 | 9038 | 0.028 | 0.2337 | No | ||
95 | ACTA1 | 840538 | 9331 | 0.023 | 0.2182 | No | ||
96 | EGR4 | 3120750 | 9432 | 0.021 | 0.2130 | No | ||
97 | MYO1E | 3140504 | 9494 | 0.020 | 0.2099 | No | ||
98 | SLC7A1 | 2450193 2710241 | 9925 | 0.013 | 0.1868 | No | ||
99 | DIXDC1 | 6980435 | 10047 | 0.011 | 0.1804 | No | ||
100 | TAGLN | 6660280 | 10085 | 0.010 | 0.1785 | No | ||
101 | HOXA5 | 6840026 | 10171 | 0.009 | 0.1740 | No | ||
102 | MYL9 | 4210750 7050138 | 10173 | 0.009 | 0.1741 | No | ||
103 | KCNMB1 | 4760139 | 10310 | 0.006 | 0.1668 | No | ||
104 | RASD2 | 3360010 | 10371 | 0.006 | 0.1636 | No | ||
105 | HOXD10 | 6100039 | 10374 | 0.006 | 0.1635 | No | ||
106 | MYH11 | 7100273 | 10648 | 0.001 | 0.1488 | No | ||
107 | KCNK3 | 2690372 | 11147 | -0.007 | 0.1219 | No | ||
108 | IL17B | 6940711 | 11182 | -0.008 | 0.1201 | No | ||
109 | SLC2A4 | 540441 | 11569 | -0.014 | 0.0994 | No | ||
110 | COL8A1 | 4590050 | 11614 | -0.015 | 0.0972 | No | ||
111 | CRK | 1230162 4780128 | 11967 | -0.022 | 0.0784 | No | ||
112 | MITF | 380056 | 12042 | -0.024 | 0.0746 | No | ||
113 | PRKAB2 | 6980300 | 12629 | -0.037 | 0.0433 | No | ||
114 | ACTR3 | 1400497 | 12632 | -0.037 | 0.0437 | No | ||
115 | ITGB6 | 2810068 4570332 | 12671 | -0.038 | 0.0421 | No | ||
116 | THBS1 | 4560494 430288 | 12677 | -0.039 | 0.0423 | No | ||
117 | TCF2 | 870338 5050632 | 12683 | -0.039 | 0.0425 | No | ||
118 | POPDC2 | 2030056 | 12759 | -0.041 | 0.0389 | No | ||
119 | LIN28 | 6590672 | 12802 | -0.042 | 0.0371 | No | ||
120 | STARD13 | 540722 | 12837 | -0.043 | 0.0358 | No | ||
121 | NR2F2 | 3170609 3310577 | 12988 | -0.048 | 0.0282 | No | ||
122 | FOSB | 1940142 | 13018 | -0.049 | 0.0272 | No | ||
123 | TRIM46 | 3520609 4590010 | 13084 | -0.051 | 0.0243 | No | ||
124 | GPR20 | 6620601 | 13118 | -0.052 | 0.0232 | No | ||
125 | EGR2 | 3800403 | 13438 | -0.065 | 0.0067 | No | ||
126 | EFHD1 | 4070358 | 13449 | -0.065 | 0.0069 | No | ||
127 | AOC3 | 6840129 | 13873 | -0.086 | -0.0150 | No | ||
128 | ROCK2 | 1780035 5720025 | 14976 | -0.199 | -0.0723 | No | ||
129 | MYL7 | 2480541 | 15019 | -0.205 | -0.0721 | No | ||
130 | SPAG7 | 4560524 | 15138 | -0.229 | -0.0758 | No | ||
131 | DUSP2 | 2370184 | 15174 | -0.235 | -0.0749 | No | ||
132 | GADD45G | 2510142 | 15193 | -0.240 | -0.0730 | No | ||
133 | LTBP1 | 780035 2100746 2760402 3780551 6550184 6860193 | 15445 | -0.293 | -0.0831 | No | ||
134 | PHF12 | 870400 3130687 | 15491 | -0.306 | -0.0819 | No | ||
135 | VCL | 4120487 | 15804 | -0.405 | -0.0939 | No | ||
136 | LCP1 | 4280397 | 16029 | -0.475 | -0.1004 | No | ||
137 | DNAJB4 | 380195 2760372 3940735 | 16042 | -0.481 | -0.0953 | No | ||
138 | USP52 | 3710215 6380133 | 16107 | -0.502 | -0.0928 | No | ||
139 | PPP1R12A | 4070066 4590162 | 16212 | -0.543 | -0.0919 | No | ||
140 | KRTCAP2 | 5220040 | 16244 | -0.553 | -0.0870 | No | ||
141 | FOXP1 | 6510433 | 16376 | -0.605 | -0.0868 | No | ||
142 | ERBB2IP | 580253 1090672 | 16411 | -0.621 | -0.0813 | No | ||
143 | SLC25A4 | 2360519 | 16458 | -0.642 | -0.0761 | No | ||
144 | MBNL1 | 2640762 7100048 | 16585 | -0.700 | -0.0746 | No | ||
145 | SCOC | 610048 2230053 | 16671 | -0.761 | -0.0701 | No | ||
146 | ABL1 | 1050593 2030050 4010114 | 16718 | -0.789 | -0.0631 | No | ||
147 | YWHAZ | 1230717 | 16788 | -0.828 | -0.0570 | No | ||
148 | EML4 | 5700373 | 16965 | -0.941 | -0.0553 | No | ||
149 | CFL1 | 2340735 | 16966 | -0.941 | -0.0440 | No | ||
150 | CDC14A | 4050132 | 16977 | -0.950 | -0.0332 | No | ||
151 | TPM3 | 670600 3170296 5670167 6650471 | 17068 | -0.998 | -0.0262 | No | ||
152 | MAPK14 | 5290731 | 17315 | -1.150 | -0.0258 | No | ||
153 | BCAS3 | 4050647 | 17407 | -1.234 | -0.0159 | No | ||
154 | AKAP12 | 1450739 | 17716 | -1.545 | -0.0142 | No | ||
155 | HOXB4 | 540131 | 17850 | -1.681 | -0.0013 | No | ||
156 | RBBP7 | 430113 450450 2370309 | 17868 | -1.701 | 0.0181 | No | ||
157 | RRM1 | 4150433 | 18035 | -1.872 | 0.0315 | No |