Details for gene set V$SREBP1

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch
Phenotype	phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch
Upregulated in class	truncNotch
GeneSet	V$SREBP1_Q6
Enrichment Score (ES)	0.41927
Normalized Enrichment Score (NES)	1.2178329
Nominal p-value	0.0698324
FDR q-value	1.0
FWER p-Value	1.0

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	GNAS	630441 1850373 4050152	32	3.653	0.0335	Yes
2	PTK2B	4730411	40	3.507	0.0669	Yes
3	CORO1A	3140609 3190020 3190037	47	3.439	0.0997	Yes
4	ETV5	110017	57	3.357	0.1316	Yes
5	RHOG	6760575	84	3.188	0.1609	Yes
6	DTX1	5900372	155	2.857	0.1846	Yes
7	CEBPB	2970019	175	2.781	0.2104	Yes
8	RHEBL1	2810576	193	2.741	0.2359	Yes
9	FXC1	3710053 4060575	216	2.661	0.2603	Yes
10	ARFIP2	1850301 4670180	401	2.274	0.2723	Yes
11	MYL6	60563 6100152	538	2.094	0.2851	Yes
12	GRWD1	6350528	617	2.004	0.3002	Yes
13	MRPS18B	5570086	689	1.922	0.3148	Yes
14	DNMT3B	2320138 4070059	1180	1.482	0.3025	Yes
15	DCTN1	1450056 6590022	1295	1.405	0.3099	Yes
16	FOXP4	6290022	1340	1.373	0.3207	Yes
17	MTMR3	1050014 4920180	1385	1.344	0.3313	Yes
18	NDRG2	450403	1396	1.340	0.3437	Yes
19	PEX16	4560044	1497	1.267	0.3505	Yes
20	ARHGDIB	4730433	1573	1.226	0.3582	Yes
21	SSBP2	2260725 2900400 4730711	1689	1.151	0.3631	Yes
22	STAT6	1190010 5720019	1810	1.075	0.3669	Yes
23	HSPG2	2510687 6220750	1889	1.032	0.3726	Yes
24	RHOA	580142 5900131 5340450	1979	0.998	0.3774	Yes
25	PDXP	5050204 460273 6040102	1991	0.996	0.3864	Yes
26	IMMT	870450 4280438	2005	0.993	0.3953	Yes
27	TYRO3	3130193	2007	0.993	0.4048	Yes
28	CLIC1	110600	2033	0.981	0.4129	Yes
29	CDC42EP4	4150338	2224	0.891	0.4112	Yes
30	DLK1	1240138	2234	0.888	0.4193	Yes
31	SPI1	1410397	2542	0.748	0.4098	No
32	ITPR3	4010632	2827	0.624	0.4004	No
33	RAB10	2360008 5890020	2891	0.603	0.4028	No
34	SYNPO2L	5390719	3111	0.523	0.3960	No
35	CLSTN3	2350685	3286	0.468	0.3911	No
36	AP1G2	780458 2690068	3307	0.461	0.3944	No
37	LBX1	1300164 4060204	3324	0.457	0.3980	No
38	PVRL1	2570167 5220519 5890500 3190309	3345	0.452	0.4012	No
39	TCF1	5390022	3417	0.435	0.4016	No
40	PDGFB	3060440 6370008	3509	0.414	0.4006	No
41	DDR1	2060044 5220180	3529	0.411	0.4036	No
42	SLCO3A1	1050408 2370156 6110072	3747	0.363	0.3953	No
43	RPS10	4560673	3885	0.341	0.3911	No
44	MAP1A	4920576	3945	0.329	0.3911	No
45	TBCC	4810021	4028	0.315	0.3897	No
46	NR1D1	2360471 770746 6590204	4046	0.313	0.3918	No
47	IMPDH2	5220138	4049	0.313	0.3947	No
48	LPHN1	1400113 3130301	4106	0.301	0.3946	No
49	A2BP1	2370390 4590593 5550014	4314	0.269	0.3859	No
50	NRGN	4280433	4501	0.244	0.3782	No
51	SYTL2	580097 5390576 6770603	4521	0.241	0.3795	No
52	PLCB3	4670402	4661	0.227	0.3741	No
53	ATE1	290491 6940722	4679	0.224	0.3754	No
54	LDLR	5670386	4732	0.218	0.3747	No
55	HOXB2	6450592	4812	0.210	0.3724	No
56	ABCG4	3440458	5026	0.189	0.3627	No
57	LRCH4	5220279 6510026	5115	0.181	0.3596	No
58	TGFB1I1	2060288 6550450	5331	0.163	0.3496	No
59	INPP4A	510215 1090541 4850093 6100519	5377	0.159	0.3487	No
60	H2AFY	4730750	5599	0.143	0.3380	No
61	BCL6B	60047	5968	0.121	0.3193	No
62	HOXA3	3610632 6020358	5970	0.121	0.3204	No
63	KLF12	1660095 4810288 5340546 6520286	6072	0.115	0.3160	No
64	DPYSL2	2100427 3130112 5700324	6141	0.112	0.3134	No
65	LGP2	4480338	6445	0.097	0.2979	No
66	SMTN	670563 1190438	6575	0.092	0.2918	No
67	FLNC	2360048 5050270	6651	0.089	0.2886	No
68	NEUROD2	5290097	6675	0.088	0.2882	No
69	MACF1	1340132 2370176 2900750 6590364	6703	0.087	0.2876	No
70	DLGAP4	4570672 5690161	6799	0.083	0.2832	No
71	MT4	4780338	6831	0.083	0.2823	No
72	KCNK7	4230576	6899	0.080	0.2795	No
73	EPO	940180	6955	0.078	0.2772	No
74	AGER	5860538 5910180	7034	0.075	0.2737	No
75	ATP6V0C	1780609	7062	0.075	0.2730	No
76	PKP3	3710048	7303	0.067	0.2606	No
77	PTRF	2260204	7434	0.063	0.2542	No
78	CRLF1	3520092	7464	0.062	0.2532	No
79	FADS3	3120079	7536	0.061	0.2499	No
80	RKHD3	6180471	7935	0.051	0.2289	No
81	HOXC4	1940193	8546	0.038	0.1961	No
82	ERF	110551 1770278	8612	0.036	0.1930	No
83	FBXO24	1230132 4610121	8755	0.033	0.1856	No
84	HIF1A	5670605	8830	0.032	0.1819	No
85	HOXA11	6980133	8863	0.031	0.1804	No
86	GREM1	3940180	8894	0.030	0.1791	No
87	LMX1A	2810239 5690324	9242	0.025	0.1605	No
88	FABP6	7000278	9385	0.022	0.1530	No
89	NFATC4	2470735	9458	0.021	0.1493	No
90	EVX1	1980471	9514	0.020	0.1465	No
91	NF1	6980433	9703	0.017	0.1365	No
92	TIMP4	6110433	9724	0.016	0.1356	No
93	LRRN1	3290154	9799	0.015	0.1317	No
94	PDE5A	130072	9812	0.015	0.1312	No
95	ANXA9	1190195	9995	0.012	0.1215	No
96	ESR1	4060372 5860193	10104	0.010	0.1157	No
97	KCNMB1	4760139	10310	0.006	0.1046	No
98	HOXD10	6100039	10374	0.006	0.1013	No
99	ZFP36L1	2510138 4120048	10657	0.001	0.0860	No
100	PAX3	50551	11247	-0.009	0.0541	No
101	SLC2A4	540441	11569	-0.014	0.0369	No
102	SALL1	5420020 7050195	11661	-0.016	0.0321	No
103	CACNB1	2940427 3710487	11679	-0.016	0.0313	No
104	GNAO1	2510292 6590487	11847	-0.020	0.0225	No
105	PLA2G3	5130739	11935	-0.021	0.0179	No
106	HYAL1	3850341	12050	-0.024	0.0120	No
107	SIX4	6760022	12181	-0.027	0.0052	No
108	SERPINI1	2940468	12219	-0.028	0.0035	No
109	EMX2	1660092	12233	-0.028	0.0030	No
110	DUSP8	6650039	12275	-0.029	0.0011	No
111	SLC4A1	6290577	12311	-0.030	-0.0005	No
112	GRID2	2680242	12497	-0.034	-0.0102	No
113	GFAP	2060092	12535	-0.035	-0.0119	No
114	GRIA1	1340152 3780750 4920440	12664	-0.038	-0.0185	No
115	GAP43	3130504	12665	-0.038	-0.0181	No
116	TCF2	870338 5050632	12683	-0.039	-0.0187	No
117	GUCA2B	4200014	12740	-0.040	-0.0213	No
118	SLC24A1	1240463	12784	-0.042	-0.0232	No
119	LIN28	6590672	12802	-0.042	-0.0238	No
120	SLC4A10	2060670	13073	-0.051	-0.0379	No
121	CACNA1D	1740315 4730731	13444	-0.065	-0.0574	No
122	KCNN3	6520600 6420138	13538	-0.069	-0.0617	No
123	MEOX2	6400288	13570	-0.071	-0.0627	No
124	DHH	2120433	13614	-0.073	-0.0644	No
125	TEAD2	6450079	13706	-0.077	-0.0686	No
126	KIF1B	1240494 2370139 4570270 6510102	13965	-0.092	-0.0817	No
127	SREBF2	3390692	14049	-0.098	-0.0852	No
128	TRAF4	3060041 4920528 6980286	14195	-0.107	-0.0920	No
129	RARG	6760136	14266	-0.114	-0.0947	No
130	LRP8	3610746 5360035	14368	-0.123	-0.0990	No
131	POU4F2	2120195 2570022	14374	-0.124	-0.0981	No
132	DSG4	3990605 6400736	14410	-0.127	-0.0988	No
133	RBX1	2120010 2340047	14472	-0.132	-0.1008	No
134	ENO2	2320068	14476	-0.133	-0.0997	No
135	SOX12	1780037	14670	-0.154	-0.1087	No
136	CLASP1	6860279	15087	-0.218	-0.1291	No
137	CLDN5	6510717	15093	-0.218	-0.1273	No
138	BAZ2A	730184	15123	-0.226	-0.1267	No
139	FBS1	2570520	15153	-0.231	-0.1260	No
140	MAPKAPK3	630520	15259	-0.253	-0.1293	No
141	ZIC4	1500082	15277	-0.256	-0.1277	No
142	REL	360707	15372	-0.279	-0.1302	No
143	SLC39A14	670300 1400093 1990711	15428	-0.288	-0.1304	No
144	GPR85	5130750 5910020	15572	-0.327	-0.1350	No
145	B4GALT2	780037	15591	-0.333	-0.1327	No
146	PCF11	1240180	15652	-0.353	-0.1326	No
147	PACSIN3	4540369 4540400 5360037 6940129	15695	-0.367	-0.1313	No
148	EN1	5360168 7050025	15795	-0.400	-0.1328	No
149	DYRK1A	3190181	15866	-0.423	-0.1326	No
150	FXYD1	1400239 6560129	15916	-0.440	-0.1310	No
151	JUP	2510671	15925	-0.443	-0.1271	No
152	NTRK3	4050687 4070167 4610026 6100484	16034	-0.477	-0.1284	No
153	TRERF1	6370017 6940138	16059	-0.485	-0.1250	No
154	STX1A	3060273	16064	-0.487	-0.1205	No
155	DDX6	2630025 6770408	16128	-0.510	-0.1190	No
156	LASP1	1690528 2190341 6420341	16129	-0.511	-0.1141	No
157	PHF15	6550066 6860673	16156	-0.519	-0.1105	No
158	YWHAQ	6760524	16184	-0.532	-0.1069	No
159	MYH10	2640673	16399	-0.614	-0.1126	No
160	PPP1R10	110136 3170725 3610484	16503	-0.666	-0.1117	No
161	NFAT5	2510411 5890195 6550152	16745	-0.804	-0.1171	No
162	EIF4G2	3800575 6860184	16927	-0.918	-0.1180	No
163	ANP32A	510044 1580095 2680037	16930	-0.919	-0.1093	No
164	SIPA1L2	4850731	16952	-0.930	-0.1015	No
165	MMP14	670079	16996	-0.964	-0.0945	No
166	ZFYVE1	60440	17010	-0.973	-0.0858	No
167	NFIX	2450152	17052	-0.991	-0.0785	No
168	SLIT3	7100132	17120	-1.016	-0.0723	No
169	EMP1	4120438	17427	-1.248	-0.0769	No
170	ATP6V1A	6590242	17513	-1.330	-0.0687	No
171	NSF	4070075	17607	-1.418	-0.0601	No
172	PIAS1	5340301	18009	-1.854	-0.0640	No
173	PDCD10	4760500	18256	-2.201	-0.0561	No
174	NMT1	5810152	18336	-2.373	-0.0375	No
175	FCHSD2	5720092	18449	-2.628	-0.0183	No
176	KPNB1	1690138	18506	-2.828	0.0060	No