Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | V$PEA3_Q6 |
Enrichment Score (ES) | 0.48566905 |
Normalized Enrichment Score (NES) | 1.4180502 |
Nominal p-value | 0.005952381 |
FDR q-value | 0.7904084 |
FWER p-Value | 0.999 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | MAPKAPK2 | 2850500 | 26 | 3.846 | 0.0308 | Yes | ||
2 | UNC93B1 | 430152 | 41 | 3.487 | 0.0593 | Yes | ||
3 | POLD4 | 2320082 | 55 | 3.377 | 0.0869 | Yes | ||
4 | RHOG | 6760575 | 84 | 3.188 | 0.1122 | Yes | ||
5 | ELOVL1 | 2450019 4760138 5340685 | 123 | 2.949 | 0.1348 | Yes | ||
6 | CD5 | 6590338 | 142 | 2.900 | 0.1582 | Yes | ||
7 | SLAMF9 | 3710300 | 158 | 2.839 | 0.1812 | Yes | ||
8 | TYSND1 | 2940273 | 182 | 2.760 | 0.2031 | Yes | ||
9 | IL2RA | 6620450 | 190 | 2.744 | 0.2257 | Yes | ||
10 | CTSW | 360368 | 465 | 2.179 | 0.2292 | Yes | ||
11 | SELL | 1190500 | 673 | 1.940 | 0.2342 | Yes | ||
12 | ZNF289 | 3610390 3870711 3940138 5340373 | 711 | 1.900 | 0.2481 | Yes | ||
13 | PTPN6 | 4230128 | 715 | 1.895 | 0.2639 | Yes | ||
14 | LPXN | 2360142 | 774 | 1.840 | 0.2762 | Yes | ||
15 | NDUFS2 | 4850020 6200402 | 837 | 1.771 | 0.2877 | Yes | ||
16 | POU2AF1 | 5690242 | 862 | 1.745 | 0.3010 | Yes | ||
17 | PRF1 | 6660309 | 945 | 1.676 | 0.3106 | Yes | ||
18 | SRRM1 | 6110025 | 948 | 1.674 | 0.3245 | Yes | ||
19 | SSBP3 | 870717 1050377 7040551 | 1140 | 1.506 | 0.3268 | Yes | ||
20 | MAP4K2 | 4200037 | 1181 | 1.482 | 0.3371 | Yes | ||
21 | DGKZ | 3460041 6400129 | 1201 | 1.471 | 0.3484 | Yes | ||
22 | TCIRG1 | 4590524 5910079 6900619 | 1455 | 1.302 | 0.3456 | Yes | ||
23 | RPS6KA4 | 2190524 | 1491 | 1.271 | 0.3544 | Yes | ||
24 | SLC2A3 | 1990377 | 1517 | 1.258 | 0.3636 | Yes | ||
25 | ESRRA | 6550242 | 1522 | 1.257 | 0.3739 | Yes | ||
26 | GPD1 | 2480095 | 1544 | 1.243 | 0.3832 | Yes | ||
27 | ARHGDIB | 4730433 | 1573 | 1.226 | 0.3919 | Yes | ||
28 | TNNI2 | 5910739 | 1610 | 1.201 | 0.4001 | Yes | ||
29 | CD53 | 5550162 | 1640 | 1.178 | 0.4084 | Yes | ||
30 | CAP1 | 2650278 | 1715 | 1.136 | 0.4139 | Yes | ||
31 | FCGR3A | 3840184 | 1765 | 1.094 | 0.4204 | Yes | ||
32 | LCK | 3360142 | 1776 | 1.087 | 0.4290 | Yes | ||
33 | BLNK | 70288 6590092 | 1942 | 1.009 | 0.4285 | Yes | ||
34 | ADRBK1 | 1340333 | 1966 | 1.002 | 0.4357 | Yes | ||
35 | IL18BP | 3450128 | 1969 | 1.000 | 0.4440 | Yes | ||
36 | MFN2 | 2260195 6100164 | 1974 | 1.000 | 0.4521 | Yes | ||
37 | LAG3 | 6860112 | 2175 | 0.911 | 0.4489 | Yes | ||
38 | VCAM1 | 2900450 | 2305 | 0.852 | 0.4491 | Yes | ||
39 | PIK4CB | 510450 1780452 | 2366 | 0.825 | 0.4527 | Yes | ||
40 | DPP3 | 2680725 3780670 | 2425 | 0.793 | 0.4563 | Yes | ||
41 | KCNQ1 | 1580050 6860441 | 2512 | 0.761 | 0.4580 | Yes | ||
42 | SPI1 | 1410397 | 2542 | 0.748 | 0.4627 | Yes | ||
43 | EPC1 | 1570050 5290095 6900193 | 2559 | 0.741 | 0.4680 | Yes | ||
44 | LRFN4 | 5670368 | 2597 | 0.723 | 0.4721 | Yes | ||
45 | CDKN2C | 5050750 5130148 | 2627 | 0.707 | 0.4764 | Yes | ||
46 | SIPA1 | 5220687 | 2672 | 0.687 | 0.4798 | Yes | ||
47 | CYR61 | 1240408 5290026 4120452 6550008 | 2750 | 0.650 | 0.4811 | Yes | ||
48 | ITPKB | 2900195 7100039 | 2766 | 0.642 | 0.4857 | Yes | ||
49 | ZRANB1 | 510373 4540278 | 2889 | 0.603 | 0.4841 | No | ||
50 | NUMA1 | 6520576 | 3038 | 0.548 | 0.4807 | No | ||
51 | ETV3 | 5360487 | 3201 | 0.493 | 0.4761 | No | ||
52 | LTBR | 2450341 | 3213 | 0.491 | 0.4796 | No | ||
53 | SLC26A9 | 3440722 5340088 7510093 | 3244 | 0.481 | 0.4820 | No | ||
54 | BCL2L14 | 2940279 | 3253 | 0.479 | 0.4856 | No | ||
55 | WASF2 | 4850592 | 3496 | 0.418 | 0.4760 | No | ||
56 | CENTD2 | 60408 2510156 6100494 | 3504 | 0.415 | 0.4791 | No | ||
57 | MMRN2 | 1740047 | 3533 | 0.410 | 0.4810 | No | ||
58 | SYTL1 | 510487 | 3642 | 0.386 | 0.4784 | No | ||
59 | ELAVL4 | 50735 3360086 5220167 | 3674 | 0.381 | 0.4799 | No | ||
60 | SORL1 | 630204 | 3684 | 0.377 | 0.4826 | No | ||
61 | CTSS | 1740056 | 3822 | 0.349 | 0.4781 | No | ||
62 | GPR120 | 2350398 | 4357 | 0.265 | 0.4514 | No | ||
63 | CD3E | 3800056 | 4405 | 0.258 | 0.4510 | No | ||
64 | NRGN | 4280433 | 4501 | 0.244 | 0.4479 | No | ||
65 | SELP | 6040193 | 4553 | 0.237 | 0.4471 | No | ||
66 | PLCB3 | 4670402 | 4661 | 0.227 | 0.4432 | No | ||
67 | SLC30A7 | 2230463 | 4719 | 0.220 | 0.4420 | No | ||
68 | RPS3 | 1570017 2370170 | 5022 | 0.190 | 0.4272 | No | ||
69 | DMBT1 | 7050270 | 5148 | 0.178 | 0.4219 | No | ||
70 | CUGBP1 | 450292 510022 7050176 7050215 | 5294 | 0.166 | 0.4155 | No | ||
71 | EPHA2 | 5890056 | 5412 | 0.156 | 0.4104 | No | ||
72 | PRDX6 | 4920397 6380601 | 5616 | 0.142 | 0.4006 | No | ||
73 | HHEX | 2340575 | 5691 | 0.138 | 0.3978 | No | ||
74 | ST7L | 840735 2360576 | 5719 | 0.135 | 0.3974 | No | ||
75 | IVL | 4560500 | 5839 | 0.128 | 0.3921 | No | ||
76 | MARK1 | 450484 | 5959 | 0.121 | 0.3866 | No | ||
77 | RUNX3 | 3800546 | 5980 | 0.121 | 0.3866 | No | ||
78 | PBXIP1 | 70131 | 7080 | 0.074 | 0.3276 | No | ||
79 | LALBA | 6940685 | 7146 | 0.072 | 0.3247 | No | ||
80 | VPS11 | 1090048 6040372 | 7181 | 0.071 | 0.3235 | No | ||
81 | PGM2L1 | 2350035 | 7185 | 0.071 | 0.3239 | No | ||
82 | IL18 | 6180039 | 7228 | 0.069 | 0.3222 | No | ||
83 | ADAMTS4 | 430435 | 7310 | 0.067 | 0.3184 | No | ||
84 | KAZALD1 | 380603 | 7507 | 0.062 | 0.3083 | No | ||
85 | FGF23 | 510746 | 7836 | 0.053 | 0.2910 | No | ||
86 | PAX6 | 1190025 | 7893 | 0.052 | 0.2884 | No | ||
87 | PDGFD | 60438 | 8092 | 0.047 | 0.2780 | No | ||
88 | FUCA1 | 610075 | 8096 | 0.047 | 0.2783 | No | ||
89 | IPO7 | 2190746 | 8346 | 0.041 | 0.2651 | No | ||
90 | XPNPEP1 | 2640750 3850315 6200242 | 8929 | 0.030 | 0.2338 | No | ||
91 | CPNE8 | 7040039 | 9151 | 0.026 | 0.2221 | No | ||
92 | NCF2 | 540129 2370441 2650133 | 9688 | 0.017 | 0.1932 | No | ||
93 | ANKRD1 | 4850685 | 9734 | 0.016 | 0.1909 | No | ||
94 | EHF | 4560088 | 9970 | 0.012 | 0.1783 | No | ||
95 | GAB2 | 1410280 2340520 4280040 | 10087 | 0.010 | 0.1721 | No | ||
96 | MMP7 | 1780497 | 10124 | 0.010 | 0.1702 | No | ||
97 | TAF5 | 3450288 5890193 6860435 | 10194 | 0.008 | 0.1665 | No | ||
98 | GPA33 | 2650044 | 10543 | 0.003 | 0.1477 | No | ||
99 | AKT3 | 1580270 3290278 | 10642 | 0.001 | 0.1424 | No | ||
100 | NCAM1 | 3140026 | 11005 | -0.005 | 0.1228 | No | ||
101 | CACNA1E | 840253 | 11094 | -0.006 | 0.1181 | No | ||
102 | CMAS | 2190129 | 12195 | -0.027 | 0.0587 | No | ||
103 | BDNF | 2940128 3520368 | 12660 | -0.038 | 0.0339 | No | ||
104 | RNASEL | 2340133 | 12702 | -0.039 | 0.0320 | No | ||
105 | XCL1 | 3800504 | 12757 | -0.041 | 0.0294 | No | ||
106 | LIN28 | 6590672 | 12802 | -0.042 | 0.0274 | No | ||
107 | ELK4 | 460494 940369 4480136 | 13060 | -0.051 | 0.0139 | No | ||
108 | SPRR4 | 5720273 | 13215 | -0.056 | 0.0060 | No | ||
109 | FUT11 | 6040692 | 13479 | -0.067 | -0.0076 | No | ||
110 | GRIN2B | 3800333 | 13634 | -0.074 | -0.0154 | No | ||
111 | CAPZA1 | 3140390 | 13665 | -0.075 | -0.0164 | No | ||
112 | SLC41A1 | 1230528 | 13681 | -0.076 | -0.0165 | No | ||
113 | HIPK1 | 110193 | 13682 | -0.076 | -0.0159 | No | ||
114 | TIAL1 | 4150048 6510605 | 13803 | -0.082 | -0.0217 | No | ||
115 | SV2A | 1450039 5570685 | 14578 | -0.142 | -0.0625 | No | ||
116 | RAB39 | 430524 | 14862 | -0.181 | -0.0763 | No | ||
117 | CBL | 6380068 | 15047 | -0.209 | -0.0845 | No | ||
118 | ANK3 | 1500161 2900435 4210154 6400100 | 15162 | -0.233 | -0.0887 | No | ||
119 | PAFAH2 | 3140451 5720593 6510014 | 15176 | -0.235 | -0.0874 | No | ||
120 | PICALM | 1940280 | 15187 | -0.238 | -0.0860 | No | ||
121 | RIN1 | 510593 | 15195 | -0.241 | -0.0843 | No | ||
122 | KCNAB2 | 4850315 | 15202 | -0.243 | -0.0826 | No | ||
123 | CAMK1D | 1660100 2350309 | 15241 | -0.251 | -0.0826 | No | ||
124 | LAMC1 | 4730025 | 15310 | -0.264 | -0.0841 | No | ||
125 | CTBP2 | 430309 3710079 | 15405 | -0.285 | -0.0868 | No | ||
126 | FEN1 | 1770541 | 15480 | -0.302 | -0.0882 | No | ||
127 | CD69 | 380167 4730088 | 15481 | -0.303 | -0.0857 | No | ||
128 | SNCG | 3120725 | 15582 | -0.331 | -0.0883 | No | ||
129 | TCEB3 | 5890156 | 15702 | -0.368 | -0.0917 | No | ||
130 | IRAK4 | 5390156 6130594 | 15705 | -0.370 | -0.0887 | No | ||
131 | GFI1 | 730180 | 15709 | -0.371 | -0.0858 | No | ||
132 | GTF2H1 | 2570746 2650148 | 15865 | -0.423 | -0.0906 | No | ||
133 | ITPR2 | 5360128 | 15879 | -0.428 | -0.0877 | No | ||
134 | ABLIM1 | 580170 3710338 6520504 | 15997 | -0.466 | -0.0901 | No | ||
135 | VDAC2 | 7000215 | 16017 | -0.471 | -0.0872 | No | ||
136 | SLC35C1 | 4540154 | 16356 | -0.598 | -0.1005 | No | ||
137 | ZDHHC5 | 1690711 | 16359 | -0.598 | -0.0956 | No | ||
138 | PUM1 | 6130500 | 16425 | -0.627 | -0.0939 | No | ||
139 | LZTS2 | 2260440 | 16443 | -0.635 | -0.0895 | No | ||
140 | TNFRSF19L | 1170168 1190358 5670270 | 16476 | -0.650 | -0.0858 | No | ||
141 | MARK2 | 7210608 | 16526 | -0.675 | -0.0827 | No | ||
142 | EXTL2 | 5050433 | 16568 | -0.690 | -0.0792 | No | ||
143 | SPATA6 | 4590373 | 16734 | -0.797 | -0.0814 | No | ||
144 | GATA3 | 6130068 | 16831 | -0.855 | -0.0795 | No | ||
145 | SEC24C | 6980707 | 16855 | -0.869 | -0.0734 | No | ||
146 | TRIM33 | 580619 2230280 3990433 6200747 | 16870 | -0.879 | -0.0668 | No | ||
147 | MR1 | 3850037 | 16935 | -0.922 | -0.0625 | No | ||
148 | CDC14A | 4050132 | 16977 | -0.950 | -0.0568 | No | ||
149 | ARF3 | 3710446 | 16988 | -0.959 | -0.0493 | No | ||
150 | DCLRE1C | 1450041 2360091 3290671 3390739 | 17291 | -1.134 | -0.0562 | No | ||
151 | NT5C2 | 4280735 4670528 | 17410 | -1.236 | -0.0522 | No | ||
152 | FLI1 | 3990142 | 17449 | -1.266 | -0.0436 | No | ||
153 | TMEM24 | 5860039 | 17491 | -1.314 | -0.0348 | No | ||
154 | LRMP | 6290193 | 17732 | -1.558 | -0.0348 | No | ||
155 | PTPRC | 130402 5290148 | 17828 | -1.663 | -0.0260 | No | ||
156 | INPPL1 | 110717 3120164 | 17899 | -1.732 | -0.0152 | No | ||
157 | CD84 | 1780168 | 18016 | -1.860 | -0.0059 | No | ||
158 | PRKACB | 4210170 | 18277 | -2.235 | -0.0012 | No | ||
159 | TRIM8 | 6130441 | 18322 | -2.332 | 0.0159 | No |