Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | V$OCT1_B |
Enrichment Score (ES) | 0.408754 |
Normalized Enrichment Score (NES) | 1.1996527 |
Nominal p-value | 0.07713885 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | HIST1H3C | 730204 | 23 | 3.948 | 0.0434 | Yes | ||
2 | HIST2H2BE | 3360184 | 43 | 3.486 | 0.0818 | Yes | ||
3 | HIST1H3B | 4780092 | 44 | 3.453 | 0.1208 | Yes | ||
4 | CD79B | 1450066 3390358 | 97 | 3.091 | 0.1529 | Yes | ||
5 | HIST1H2AB | 2680465 | 172 | 2.796 | 0.1805 | Yes | ||
6 | HIST1H2BK | 6130433 | 271 | 2.499 | 0.2034 | Yes | ||
7 | PIK3CD | 3060546 | 340 | 2.382 | 0.2267 | Yes | ||
8 | BAT2 | 6650435 | 469 | 2.170 | 0.2443 | Yes | ||
9 | HIST1H2BM | 3170168 | 585 | 2.033 | 0.2610 | Yes | ||
10 | UBE2S | 1850110 | 875 | 1.734 | 0.2649 | Yes | ||
11 | ARHGAP4 | 1940022 | 887 | 1.724 | 0.2838 | Yes | ||
12 | HIST1H2BB | 1340035 | 980 | 1.633 | 0.2973 | Yes | ||
13 | ACBD4 | 6980079 | 991 | 1.628 | 0.3152 | Yes | ||
14 | SERTAD4 | 130593 | 1192 | 1.476 | 0.3210 | Yes | ||
15 | SCML4 | 2850088 | 1291 | 1.407 | 0.3316 | Yes | ||
16 | ESRRA | 6550242 | 1522 | 1.257 | 0.3333 | Yes | ||
17 | SESN3 | 110687 | 1635 | 1.181 | 0.3406 | Yes | ||
18 | RRAS | 4150609 | 1766 | 1.094 | 0.3459 | Yes | ||
19 | SH3GL3 | 3800112 | 1781 | 1.084 | 0.3574 | Yes | ||
20 | THRAP5 | 2030403 | 1935 | 1.011 | 0.3605 | Yes | ||
21 | BLNK | 70288 6590092 | 1942 | 1.009 | 0.3716 | Yes | ||
22 | HIST1H2BC | 2570156 6520315 | 1973 | 1.000 | 0.3813 | Yes | ||
23 | FZD2 | 6480154 | 2076 | 0.962 | 0.3866 | Yes | ||
24 | TBXAS1 | 5050053 6900286 | 2095 | 0.949 | 0.3964 | Yes | ||
25 | TWIST1 | 5130619 | 2209 | 0.898 | 0.4004 | Yes | ||
26 | RHOB | 1500309 | 2694 | 0.678 | 0.3818 | Yes | ||
27 | AXUD1 | 1230053 | 2735 | 0.659 | 0.3871 | Yes | ||
28 | CYR61 | 1240408 5290026 4120452 6550008 | 2750 | 0.650 | 0.3937 | Yes | ||
29 | ITPR3 | 4010632 | 2827 | 0.624 | 0.3966 | Yes | ||
30 | BCL2 | 730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164 | 2962 | 0.579 | 0.3959 | Yes | ||
31 | KCTD12 | 7050091 | 2987 | 0.569 | 0.4010 | Yes | ||
32 | CDX2 | 3850349 | 2992 | 0.567 | 0.4072 | Yes | ||
33 | POU3F4 | 870274 | 3076 | 0.535 | 0.4088 | Yes | ||
34 | POLM | 2630440 | 3299 | 0.464 | 0.4020 | No | ||
35 | SLC25A12 | 7400731 | 3676 | 0.380 | 0.3858 | No | ||
36 | RHOBTB2 | 1570129 2320253 3520253 | 3771 | 0.358 | 0.3848 | No | ||
37 | ADORA2A | 1990687 | 3810 | 0.351 | 0.3867 | No | ||
38 | DUSP6 | 5910286 7100070 | 3988 | 0.323 | 0.3807 | No | ||
39 | NRAS | 6900577 | 4037 | 0.314 | 0.3817 | No | ||
40 | NR1D1 | 2360471 770746 6590204 | 4046 | 0.313 | 0.3848 | No | ||
41 | TBR1 | 5130053 | 4127 | 0.297 | 0.3838 | No | ||
42 | HPCAL4 | 2600484 | 4178 | 0.289 | 0.3844 | No | ||
43 | CSMD3 | 1660427 1940687 | 4225 | 0.280 | 0.3850 | No | ||
44 | TRPM1 | 50746 2060301 5130100 5720129 | 4336 | 0.267 | 0.3821 | No | ||
45 | PTHLH | 5290739 | 4393 | 0.260 | 0.3820 | No | ||
46 | HOXA10 | 6110397 7100458 | 4449 | 0.252 | 0.3818 | No | ||
47 | LRRTM4 | 5910100 | 4504 | 0.243 | 0.3817 | No | ||
48 | SRF | 70139 2320039 | 4578 | 0.235 | 0.3804 | No | ||
49 | KIF13A | 5390750 | 4676 | 0.224 | 0.3776 | No | ||
50 | BCDO2 | 4560279 | 4715 | 0.220 | 0.3781 | No | ||
51 | EAF2 | 4280711 5080324 | 4727 | 0.218 | 0.3799 | No | ||
52 | SLITRK6 | 7320739 | 4786 | 0.213 | 0.3792 | No | ||
53 | LRCH4 | 5220279 6510026 | 5115 | 0.181 | 0.3635 | No | ||
54 | CSF3 | 2230193 6660707 | 5118 | 0.181 | 0.3654 | No | ||
55 | VPREB3 | 3780131 | 5207 | 0.173 | 0.3626 | No | ||
56 | SOX2 | 630487 2230491 | 5382 | 0.159 | 0.3549 | No | ||
57 | PFKFB1 | 2370128 | 5415 | 0.156 | 0.3550 | No | ||
58 | CDH13 | 5130368 5340114 | 5514 | 0.149 | 0.3513 | No | ||
59 | COL23A1 | 2030358 | 5697 | 0.137 | 0.3430 | No | ||
60 | CPD | 5360403 5860685 | 5802 | 0.130 | 0.3388 | No | ||
61 | SLC6A15 | 5290176 6040017 | 5837 | 0.128 | 0.3384 | No | ||
62 | NXPH1 | 3870546 | 6055 | 0.116 | 0.3280 | No | ||
63 | KLF12 | 1660095 4810288 5340546 6520286 | 6072 | 0.115 | 0.3284 | No | ||
64 | HIST1H2AC | 3130292 | 6094 | 0.114 | 0.3286 | No | ||
65 | POU2F3 | 2030601 | 6096 | 0.114 | 0.3298 | No | ||
66 | DMD | 1740041 3990332 | 6236 | 0.107 | 0.3235 | No | ||
67 | NRL | 4210110 | 6303 | 0.105 | 0.3211 | No | ||
68 | SP6 | 60484 510452 2690333 | 6486 | 0.096 | 0.3123 | No | ||
69 | STAG1 | 1190300 1400722 4590100 | 6607 | 0.091 | 0.3068 | No | ||
70 | SLC1A2 | 2230520 | 6701 | 0.087 | 0.3027 | No | ||
71 | DLGAP4 | 4570672 5690161 | 6799 | 0.083 | 0.2984 | No | ||
72 | DNAH5 | 7040315 | 6834 | 0.082 | 0.2975 | No | ||
73 | ETV1 | 70735 2940603 5080463 | 6938 | 0.079 | 0.2928 | No | ||
74 | BTK | 3130044 | 6974 | 0.077 | 0.2918 | No | ||
75 | CLCA3 | 6510167 | 7051 | 0.075 | 0.2885 | No | ||
76 | SYNPR | 2810400 | 7086 | 0.074 | 0.2875 | No | ||
77 | CDX4 | 6380164 | 7096 | 0.073 | 0.2878 | No | ||
78 | NEUROD6 | 4670731 | 7482 | 0.062 | 0.2676 | No | ||
79 | TCEAL1 | 870577 | 7492 | 0.062 | 0.2679 | No | ||
80 | ADORA1 | 6370520 | 7558 | 0.060 | 0.2650 | No | ||
81 | VSNL1 | 3120017 | 7643 | 0.058 | 0.2611 | No | ||
82 | HOXC5 | 1580017 | 7717 | 0.056 | 0.2578 | No | ||
83 | PRDM1 | 3170347 3520301 | 7768 | 0.055 | 0.2557 | No | ||
84 | PAX6 | 1190025 | 7893 | 0.052 | 0.2495 | No | ||
85 | TMOD2 | 5130180 | 8136 | 0.046 | 0.2369 | No | ||
86 | CRISP1 | 50181 | 8224 | 0.044 | 0.2327 | No | ||
87 | NRXN3 | 1400546 3360471 | 8373 | 0.041 | 0.2251 | No | ||
88 | GPM6A | 1660044 2750152 | 8418 | 0.040 | 0.2232 | No | ||
89 | HDAC9 | 1990010 2260133 | 8592 | 0.037 | 0.2142 | No | ||
90 | LHX6 | 2360731 3360397 | 8650 | 0.036 | 0.2115 | No | ||
91 | FBXO24 | 1230132 4610121 | 8755 | 0.033 | 0.2063 | No | ||
92 | RGS13 | 3780722 | 8910 | 0.030 | 0.1983 | No | ||
93 | ALK | 730008 | 9014 | 0.028 | 0.1930 | No | ||
94 | UPK3A | 1410717 | 9030 | 0.028 | 0.1925 | No | ||
95 | NFIA | 2760129 5860278 | 9045 | 0.028 | 0.1920 | No | ||
96 | HIST1H2AH | 3710333 | 9278 | 0.024 | 0.1797 | No | ||
97 | SLC19A3 | 2650601 | 9296 | 0.024 | 0.1791 | No | ||
98 | GPR4 | 2060358 | 9350 | 0.023 | 0.1765 | No | ||
99 | HOXA13 | 3120647 | 9444 | 0.021 | 0.1716 | No | ||
100 | ITSN1 | 2640577 | 9525 | 0.020 | 0.1675 | No | ||
101 | EPHB3 | 6650341 | 9595 | 0.019 | 0.1640 | No | ||
102 | DPYSL3 | 1580594 | 9755 | 0.016 | 0.1556 | No | ||
103 | LRRN1 | 3290154 | 9799 | 0.015 | 0.1534 | No | ||
104 | PCDH20 | 4200576 | 9913 | 0.013 | 0.1474 | No | ||
105 | EHF | 4560088 | 9970 | 0.012 | 0.1445 | No | ||
106 | GAB2 | 1410280 2340520 4280040 | 10087 | 0.010 | 0.1383 | No | ||
107 | ALDH1A1 | 6520706 | 10328 | 0.006 | 0.1254 | No | ||
108 | NR2C2 | 6100097 | 10393 | 0.005 | 0.1220 | No | ||
109 | PIPOX | 70750 | 10810 | -0.002 | 0.0994 | No | ||
110 | TLL2 | 6220040 | 10955 | -0.004 | 0.0916 | No | ||
111 | PCYT1B | 1780402 | 11274 | -0.009 | 0.0745 | No | ||
112 | GNB3 | 1230167 | 11304 | -0.009 | 0.0730 | No | ||
113 | SKIL | 1090364 | 11420 | -0.012 | 0.0669 | No | ||
114 | FGF12 | 1740446 2360037 | 11673 | -0.016 | 0.0534 | No | ||
115 | MITF | 380056 | 12042 | -0.024 | 0.0337 | No | ||
116 | COL25A1 | 1580072 4280537 4480168 5290441 7040563 | 12064 | -0.024 | 0.0329 | No | ||
117 | CD86 | 3390471 6200280 | 12216 | -0.027 | 0.0250 | No | ||
118 | LIPG | 1770040 | 12321 | -0.030 | 0.0197 | No | ||
119 | PRKG1 | 4120671 | 12437 | -0.032 | 0.0138 | No | ||
120 | IRX4 | 1980102 | 12522 | -0.034 | 0.0096 | No | ||
121 | SATB2 | 2470181 | 12557 | -0.035 | 0.0082 | No | ||
122 | GPC4 | 5910408 | 12562 | -0.035 | 0.0084 | No | ||
123 | NEUROG1 | 380341 | 12565 | -0.035 | 0.0086 | No | ||
124 | SILV | 2350673 | 12636 | -0.037 | 0.0053 | No | ||
125 | BDNF | 2940128 3520368 | 12660 | -0.038 | 0.0044 | No | ||
126 | TCF2 | 870338 5050632 | 12683 | -0.039 | 0.0037 | No | ||
127 | SLC24A1 | 1240463 | 12784 | -0.042 | -0.0013 | No | ||
128 | SFRP2 | 4850097 | 12899 | -0.045 | -0.0069 | No | ||
129 | HOXB6 | 4210739 | 12941 | -0.046 | -0.0086 | No | ||
130 | LYN | 6040600 | 13008 | -0.048 | -0.0117 | No | ||
131 | TSC1 | 1850672 | 13024 | -0.049 | -0.0119 | No | ||
132 | ARPC5 | 1740411 3450300 | 13268 | -0.058 | -0.0245 | No | ||
133 | EGR2 | 3800403 | 13438 | -0.065 | -0.0329 | No | ||
134 | FGF14 | 2630390 3520075 6770048 | 13453 | -0.065 | -0.0329 | No | ||
135 | KCNN3 | 6520600 6420138 | 13538 | -0.069 | -0.0367 | No | ||
136 | MGAT5B | 380131 2570364 | 13584 | -0.071 | -0.0383 | No | ||
137 | RRM2B | 1690025 1690465 4010400 | 13667 | -0.076 | -0.0419 | No | ||
138 | PIM2 | 840136 5720692 7100577 | 13685 | -0.076 | -0.0420 | No | ||
139 | SPRR2B | 60037 | 13688 | -0.076 | -0.0412 | No | ||
140 | RAB26 | 5910025 | 13789 | -0.082 | -0.0457 | No | ||
141 | NDNL2 | 6550458 | 13836 | -0.084 | -0.0473 | No | ||
142 | E2F3 | 50162 460180 | 13868 | -0.086 | -0.0480 | No | ||
143 | CNNM4 | 1740347 | 13881 | -0.086 | -0.0477 | No | ||
144 | SREBF2 | 3390692 | 14049 | -0.098 | -0.0556 | No | ||
145 | NRXN1 | 460408 5340270 6370066 | 14110 | -0.101 | -0.0577 | No | ||
146 | FSTL5 | 770280 | 14169 | -0.106 | -0.0597 | No | ||
147 | KCTD6 | 4070435 | 14279 | -0.115 | -0.0643 | No | ||
148 | GPRC5B | 2760114 | 14330 | -0.120 | -0.0656 | No | ||
149 | MID1 | 4070114 4760458 | 14377 | -0.124 | -0.0667 | No | ||
150 | NR6A1 | 4010347 | 14404 | -0.126 | -0.0667 | No | ||
151 | MAP2K6 | 1230056 2940204 | 14593 | -0.145 | -0.0753 | No | ||
152 | PRRX1 | 4120193 4480390 | 14623 | -0.149 | -0.0752 | No | ||
153 | ASCL3 | 4570484 | 14627 | -0.149 | -0.0737 | No | ||
154 | HIST2H2AC | 2030600 | 14692 | -0.156 | -0.0754 | No | ||
155 | OLIG3 | 1050603 | 14794 | -0.171 | -0.0789 | No | ||
156 | RGL1 | 1500097 6900450 | 14908 | -0.188 | -0.0829 | No | ||
157 | GFI1B | 4570131 | 15009 | -0.204 | -0.0860 | No | ||
158 | MRAS | 2030524 | 15212 | -0.246 | -0.0942 | No | ||
159 | CRYZL1 | 730022 2320044 | 15323 | -0.268 | -0.0972 | No | ||
160 | REL | 360707 | 15372 | -0.279 | -0.0966 | No | ||
161 | CDK2 | 130484 2260301 4010088 5050110 | 15400 | -0.284 | -0.0949 | No | ||
162 | NEDD4 | 460736 1190280 | 15607 | -0.339 | -0.1022 | No | ||
163 | THRA | 6770341 110164 1990600 | 15621 | -0.343 | -0.0990 | No | ||
164 | GUCA1A | 6020338 | 15728 | -0.377 | -0.1005 | No | ||
165 | LDB2 | 5670441 6110170 | 15818 | -0.409 | -0.1007 | No | ||
166 | PDE4D | 2470528 6660014 | 15917 | -0.441 | -0.1011 | No | ||
167 | ZHX2 | 2900452 | 15981 | -0.461 | -0.0993 | No | ||
168 | FES | 3120129 5550600 | 16131 | -0.511 | -0.1016 | No | ||
169 | ATF7IP | 2690176 6770021 | 16210 | -0.541 | -0.0997 | No | ||
170 | FOXP1 | 6510433 | 16376 | -0.605 | -0.1018 | No | ||
171 | TCF12 | 3610324 7000156 | 16383 | -0.608 | -0.0953 | No | ||
172 | WNT6 | 4570364 | 16391 | -0.610 | -0.0887 | No | ||
173 | CSNK1E | 2850347 5050093 6110301 | 16546 | -0.684 | -0.0894 | No | ||
174 | SCOC | 610048 2230053 | 16671 | -0.761 | -0.0875 | No | ||
175 | LPL | 1450735 2970706 | 16673 | -0.762 | -0.0789 | No | ||
176 | STAT4 | 1660373 3130019 | 16725 | -0.792 | -0.0727 | No | ||
177 | NOTCH1 | 3390114 | 16787 | -0.827 | -0.0667 | No | ||
178 | PPARGC1B | 3290114 | 16851 | -0.866 | -0.0603 | No | ||
179 | OTX2 | 1190471 | 16926 | -0.918 | -0.0540 | No | ||
180 | PTEN | 3390064 | 17207 | -1.066 | -0.0571 | No | ||
181 | BIN3 | 380551 | 17250 | -1.101 | -0.0469 | No | ||
182 | IFIT2 | 4810735 | 17270 | -1.121 | -0.0353 | No | ||
183 | MBIP | 2640524 5570441 | 17494 | -1.315 | -0.0325 | No | ||
184 | SH3BGRL | 2060110 | 17577 | -1.394 | -0.0212 | No | ||
185 | TSGA14 | 6660465 | 17987 | -1.829 | -0.0227 | No | ||
186 | H3F3B | 1410300 | 18304 | -2.281 | -0.0141 | No | ||
187 | NFYB | 1850053 | 18478 | -2.739 | 0.0075 | No |