Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | V$NFKB_Q6_01 |
Enrichment Score (ES) | 0.4184076 |
Normalized Enrichment Score (NES) | 1.2171512 |
Nominal p-value | 0.08035714 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | BATF | 6760390 | 19 | 4.143 | 0.0409 | Yes | ||
2 | ARHGAP8 | 380333 5390487 | 53 | 3.405 | 0.0736 | Yes | ||
3 | RHOG | 6760575 | 84 | 3.188 | 0.1043 | Yes | ||
4 | IL2RA | 6620450 | 190 | 2.744 | 0.1264 | Yes | ||
5 | MRPS6 | 870164 | 365 | 2.339 | 0.1406 | Yes | ||
6 | FBXL12 | 2230040 3520008 | 522 | 2.115 | 0.1536 | Yes | ||
7 | IL27RA | 940093 | 744 | 1.864 | 0.1605 | Yes | ||
8 | NEK8 | 5700180 | 870 | 1.739 | 0.1713 | Yes | ||
9 | IL4I1 | 3190161 | 1047 | 1.578 | 0.1777 | Yes | ||
10 | EIF5A | 1500059 5290022 6370026 | 1098 | 1.536 | 0.1906 | Yes | ||
11 | RELB | 1400048 | 1117 | 1.525 | 0.2051 | Yes | ||
12 | UBE2H | 1980142 2970079 | 1161 | 1.491 | 0.2178 | Yes | ||
13 | MAP4K2 | 4200037 | 1181 | 1.482 | 0.2318 | Yes | ||
14 | ILK | 870601 4480180 | 1200 | 1.471 | 0.2457 | Yes | ||
15 | CCL5 | 3710397 | 1229 | 1.453 | 0.2589 | Yes | ||
16 | NDRG2 | 450403 | 1396 | 1.340 | 0.2635 | Yes | ||
17 | TRIB2 | 4120605 | 1435 | 1.321 | 0.2748 | Yes | ||
18 | SIRT2 | 630494 | 1487 | 1.273 | 0.2850 | Yes | ||
19 | JAK3 | 70347 3290008 | 1508 | 1.262 | 0.2966 | Yes | ||
20 | SEC61A1 | 3390437 | 1575 | 1.225 | 0.3055 | Yes | ||
21 | MAP3K11 | 7000039 | 1593 | 1.210 | 0.3168 | Yes | ||
22 | EBI3 | 5340300 | 1649 | 1.172 | 0.3257 | Yes | ||
23 | PFN1 | 6130132 | 1701 | 1.144 | 0.3345 | Yes | ||
24 | NFKBIA | 1570152 | 1757 | 1.101 | 0.3427 | Yes | ||
25 | STAT6 | 1190010 5720019 | 1810 | 1.075 | 0.3507 | Yes | ||
26 | NFKB2 | 2320670 | 1817 | 1.069 | 0.3612 | Yes | ||
27 | LTB | 3990672 | 1925 | 1.016 | 0.3657 | Yes | ||
28 | MSC | 5080139 | 1953 | 1.005 | 0.3745 | Yes | ||
29 | TOP1 | 770471 4060632 6650324 | 2058 | 0.968 | 0.3786 | Yes | ||
30 | ENO3 | 5270136 | 2060 | 0.967 | 0.3884 | Yes | ||
31 | RASGRP4 | 540102 | 2101 | 0.945 | 0.3958 | Yes | ||
32 | EDG5 | 2640300 | 2137 | 0.930 | 0.4033 | Yes | ||
33 | CLCN1 | 840161 | 2292 | 0.858 | 0.4036 | Yes | ||
34 | VCAM1 | 2900450 | 2305 | 0.852 | 0.4116 | Yes | ||
35 | GADD45B | 2350408 | 2500 | 0.766 | 0.4089 | Yes | ||
36 | NFKBIB | 2260167 | 2552 | 0.743 | 0.4136 | Yes | ||
37 | KRTAP13-1 | 2600242 | 2722 | 0.662 | 0.4112 | Yes | ||
38 | ASH1L | 2510402 5360687 6650685 | 2746 | 0.652 | 0.4165 | Yes | ||
39 | GPHN | 3290195 3840121 | 3009 | 0.562 | 0.4080 | Yes | ||
40 | CENTB5 | 5690128 | 3041 | 0.547 | 0.4119 | Yes | ||
41 | TNIP1 | 2510279 5900041 6510435 | 3126 | 0.519 | 0.4126 | Yes | ||
42 | TNFRSF1B | 3990035 5860372 | 3152 | 0.510 | 0.4164 | Yes | ||
43 | MMP9 | 580338 | 3236 | 0.483 | 0.4168 | Yes | ||
44 | TP53 | 6130707 | 3380 | 0.442 | 0.4135 | Yes | ||
45 | TCF1 | 5390022 | 3417 | 0.435 | 0.4160 | Yes | ||
46 | MAG | 2370037 | 3491 | 0.419 | 0.4163 | Yes | ||
47 | DDR1 | 2060044 5220180 | 3529 | 0.411 | 0.4184 | Yes | ||
48 | DCAMKL1 | 540095 2690092 | 3720 | 0.369 | 0.4119 | No | ||
49 | DUSP6 | 5910286 7100070 | 3988 | 0.323 | 0.4006 | No | ||
50 | SLAMF8 | 1230048 | 4059 | 0.310 | 0.4000 | No | ||
51 | PCSK2 | 360017 430528 5900619 | 4186 | 0.287 | 0.3961 | No | ||
52 | TRIM47 | 5080717 | 4213 | 0.283 | 0.3975 | No | ||
53 | SOX5 | 2370576 2900167 3190128 5050528 | 4329 | 0.268 | 0.3940 | No | ||
54 | RND1 | 5080300 | 4369 | 0.264 | 0.3946 | No | ||
55 | PTHLH | 5290739 | 4393 | 0.260 | 0.3960 | No | ||
56 | IL13 | 7040021 | 4590 | 0.235 | 0.3877 | No | ||
57 | TNFSF18 | 1990458 2850520 | 4690 | 0.222 | 0.3846 | No | ||
58 | SEMA3B | 5570563 | 4890 | 0.202 | 0.3759 | No | ||
59 | PAPPA | 4230463 | 4896 | 0.202 | 0.3776 | No | ||
60 | GRK5 | 1940348 4670053 | 5015 | 0.190 | 0.3732 | No | ||
61 | SNAP25 | 360520 | 5096 | 0.183 | 0.3707 | No | ||
62 | CSF3 | 2230193 6660707 | 5118 | 0.181 | 0.3714 | No | ||
63 | CNTNAP1 | 6650132 | 5159 | 0.177 | 0.3710 | No | ||
64 | FUT7 | 2900736 | 5196 | 0.173 | 0.3708 | No | ||
65 | DAP3 | 1660528 2120039 5420593 | 5490 | 0.151 | 0.3565 | No | ||
66 | PTGES | 1690075 | 5553 | 0.147 | 0.3546 | No | ||
67 | HSD3B7 | 1410129 | 5597 | 0.143 | 0.3537 | No | ||
68 | TNFRSF9 | 2510400 6650484 | 5701 | 0.137 | 0.3495 | No | ||
69 | BMP2K | 60541 5570504 | 5753 | 0.133 | 0.3481 | No | ||
70 | SMPD3 | 520164 | 5815 | 0.130 | 0.3461 | No | ||
71 | MOBKL2C | 2640088 3830017 | 5948 | 0.122 | 0.3402 | No | ||
72 | BCL6B | 60047 | 5968 | 0.121 | 0.3404 | No | ||
73 | PPP1R13B | 4010605 4760181 | 6064 | 0.116 | 0.3364 | No | ||
74 | POU2F3 | 2030601 | 6096 | 0.114 | 0.3359 | No | ||
75 | IFNB1 | 1400142 | 6317 | 0.104 | 0.3250 | No | ||
76 | SP6 | 60484 510452 2690333 | 6486 | 0.096 | 0.3169 | No | ||
77 | C1QL1 | 2030465 | 6724 | 0.086 | 0.3049 | No | ||
78 | LTA | 1740088 | 6769 | 0.085 | 0.3034 | No | ||
79 | RASSF2 | 2480079 5720546 | 6822 | 0.083 | 0.3014 | No | ||
80 | FTHL17 | 6550193 | 6883 | 0.080 | 0.2990 | No | ||
81 | ETV1 | 70735 2940603 5080463 | 6938 | 0.079 | 0.2968 | No | ||
82 | GABRB1 | 6760193 | 6992 | 0.076 | 0.2947 | No | ||
83 | IER5 | 2350575 | 7003 | 0.076 | 0.2950 | No | ||
84 | TSLP | 730408 1990500 | 7256 | 0.069 | 0.2820 | No | ||
85 | ZBTB11 | 6520092 | 7317 | 0.067 | 0.2794 | No | ||
86 | HSD11B2 | 5900053 | 7629 | 0.058 | 0.2632 | No | ||
87 | TNFSF15 | 360341 | 7718 | 0.056 | 0.2590 | No | ||
88 | IL27 | 1990324 | 7737 | 0.056 | 0.2586 | No | ||
89 | NTN1 | 5700600 | 7807 | 0.054 | 0.2554 | No | ||
90 | ALG6 | 4060131 | 7848 | 0.053 | 0.2537 | No | ||
91 | FGF1 | 4780435 5670601 | 8344 | 0.041 | 0.2273 | No | ||
92 | PHOX2B | 5270075 | 8517 | 0.038 | 0.2184 | No | ||
93 | ARHGEF2 | 3360577 | 8524 | 0.038 | 0.2185 | No | ||
94 | GATA4 | 1410215 2690609 | 8583 | 0.037 | 0.2157 | No | ||
95 | GREM1 | 3940180 | 8894 | 0.030 | 0.1992 | No | ||
96 | SLC6A12 | 3170685 | 9664 | 0.018 | 0.1577 | No | ||
97 | EHF | 4560088 | 9970 | 0.012 | 0.1413 | No | ||
98 | RIN2 | 2450184 | 10293 | 0.007 | 0.1239 | No | ||
99 | MSX1 | 2650309 | 10361 | 0.006 | 0.1203 | No | ||
100 | IL7 | 5360440 | 10430 | 0.005 | 0.1167 | No | ||
101 | MADCAM1 | 1580010 | 10557 | 0.003 | 0.1099 | No | ||
102 | IL1RN | 2370333 | 10640 | 0.001 | 0.1055 | No | ||
103 | PTPRJ | 4010707 | 10982 | -0.004 | 0.0870 | No | ||
104 | IL23A | 6290044 | 11513 | -0.013 | 0.0585 | No | ||
105 | AP1S2 | 780279 4280707 | 11658 | -0.016 | 0.0508 | No | ||
106 | MITF | 380056 | 12042 | -0.024 | 0.0303 | No | ||
107 | BDNF | 2940128 3520368 | 12660 | -0.038 | -0.0027 | No | ||
108 | UBE2I | 2680056 6350446 | 12954 | -0.047 | -0.0182 | No | ||
109 | NR2F2 | 3170609 3310577 | 12988 | -0.048 | -0.0195 | No | ||
110 | BAI2 | 380632 630113 6650170 | 13080 | -0.051 | -0.0239 | No | ||
111 | EDN2 | 6760647 | 13676 | -0.076 | -0.0553 | No | ||
112 | GRIN2D | 6620372 | 13825 | -0.083 | -0.0625 | No | ||
113 | GNG4 | 2630600 | 13846 | -0.085 | -0.0627 | No | ||
114 | UBD | 5570632 | 13863 | -0.086 | -0.0627 | No | ||
115 | ELMO1 | 110338 1190451 1580148 1850609 2350706 2370369 2450129 3840113 4150184 4280079 6290066 6380435 6770494 7100180 | 13915 | -0.089 | -0.0646 | No | ||
116 | CHD4 | 5420059 6130338 6380717 | 13979 | -0.093 | -0.0671 | No | ||
117 | RFX5 | 5420128 | 14009 | -0.095 | -0.0677 | No | ||
118 | TBX20 | 2230279 4920102 6980020 | 14155 | -0.105 | -0.0745 | No | ||
119 | FGF17 | 3130022 | 14165 | -0.106 | -0.0739 | No | ||
120 | TRAF4 | 3060041 4920528 6980286 | 14195 | -0.107 | -0.0744 | No | ||
121 | HTR3B | 430438 520301 | 14198 | -0.108 | -0.0734 | No | ||
122 | KLK9 | 4120164 | 14207 | -0.109 | -0.0727 | No | ||
123 | WNT10A | 2100706 | 14347 | -0.122 | -0.0790 | No | ||
124 | BIRC3 | 6550411 | 14380 | -0.125 | -0.0795 | No | ||
125 | ZNRF1 | 70592 | 14446 | -0.130 | -0.0817 | No | ||
126 | ERN1 | 2360403 | 14585 | -0.143 | -0.0877 | No | ||
127 | ASCL3 | 4570484 | 14627 | -0.149 | -0.0885 | No | ||
128 | NLK | 2030010 2450041 | 15161 | -0.233 | -0.1150 | No | ||
129 | HIVEP1 | 3850632 | 15209 | -0.245 | -0.1150 | No | ||
130 | BLR1 | 1500300 5420017 | 15275 | -0.256 | -0.1160 | No | ||
131 | ZIC4 | 1500082 | 15277 | -0.256 | -0.1134 | No | ||
132 | DUSP22 | 4280010 5550546 | 15300 | -0.263 | -0.1120 | No | ||
133 | SHOX2 | 3190438 6450059 | 15383 | -0.282 | -0.1136 | No | ||
134 | CD69 | 380167 4730088 | 15481 | -0.303 | -0.1158 | No | ||
135 | TCEA2 | 6370546 | 15714 | -0.373 | -0.1245 | No | ||
136 | CREB1 | 1500717 2230358 3610600 6550601 | 15718 | -0.374 | -0.1209 | No | ||
137 | COL27A1 | 1740390 | 15724 | -0.375 | -0.1174 | No | ||
138 | IL6ST | 5890047 | 15820 | -0.409 | -0.1184 | No | ||
139 | GNB1 | 2120397 | 15975 | -0.459 | -0.1221 | No | ||
140 | SOCS2 | 4760692 | 15983 | -0.461 | -0.1178 | No | ||
141 | NR3C1 | 630563 | 16015 | -0.470 | -0.1147 | No | ||
142 | USP52 | 3710215 6380133 | 16107 | -0.502 | -0.1146 | No | ||
143 | EGF | 5220154 | 16142 | -0.515 | -0.1112 | No | ||
144 | IL12A | 7100551 | 16333 | -0.588 | -0.1155 | No | ||
145 | AMOTL1 | 380279 | 16466 | -0.646 | -0.1162 | No | ||
146 | SMOC1 | 840039 | 16510 | -0.670 | -0.1117 | No | ||
147 | BMF | 610102 | 16518 | -0.672 | -0.1053 | No | ||
148 | XPO6 | 3940019 | 16543 | -0.683 | -0.0996 | No | ||
149 | RALGDS | 430463 | 16664 | -0.757 | -0.0985 | No | ||
150 | NFAT5 | 2510411 5890195 6550152 | 16745 | -0.804 | -0.0947 | No | ||
151 | RBMS1 | 6400014 | 16951 | -0.929 | -0.0964 | No | ||
152 | PCBP4 | 6350722 | 17053 | -0.991 | -0.0918 | No | ||
153 | ICAM1 | 6980138 | 17164 | -1.039 | -0.0872 | No | ||
154 | REV3L | 1090717 | 17192 | -1.054 | -0.0780 | No | ||
155 | BCL3 | 3990440 | 17204 | -1.061 | -0.0679 | No | ||
156 | CYLD | 6590079 | 17461 | -1.276 | -0.0688 | No | ||
157 | PRKCD | 770592 | 17702 | -1.525 | -0.0664 | No | ||
158 | ATP1B1 | 3130594 | 17741 | -1.572 | -0.0525 | No | ||
159 | UACA | 1190725 | 17874 | -1.708 | -0.0424 | No | ||
160 | UPF2 | 4810471 | 17962 | -1.793 | -0.0290 | No | ||
161 | RAP2C | 1690132 | 18028 | -1.868 | -0.0136 | No | ||
162 | UBE2D3 | 3190452 | 18074 | -1.915 | 0.0034 | No | ||
163 | SIN3A | 2190121 | 18425 | -2.561 | 0.0104 | No |