Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | V$NFKAPPAB_01 |
Enrichment Score (ES) | 0.40578762 |
Normalized Enrichment Score (NES) | 1.191284 |
Nominal p-value | 0.10130246 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | ARHGAP8 | 380333 5390487 | 53 | 3.405 | 0.0292 | Yes | ||
2 | CXCL16 | 510278 | 114 | 2.989 | 0.0541 | Yes | ||
3 | IL2RA | 6620450 | 190 | 2.744 | 0.0759 | Yes | ||
4 | ETV6 | 610524 | 460 | 2.182 | 0.0819 | Yes | ||
5 | FBXL12 | 2230040 3520008 | 522 | 2.115 | 0.0985 | Yes | ||
6 | IL27RA | 940093 | 744 | 1.864 | 0.1040 | Yes | ||
7 | SLC11A2 | 3140603 | 788 | 1.824 | 0.1189 | Yes | ||
8 | IL4I1 | 3190161 | 1047 | 1.578 | 0.1198 | Yes | ||
9 | EIF5A | 1500059 5290022 6370026 | 1098 | 1.536 | 0.1315 | Yes | ||
10 | RELB | 1400048 | 1117 | 1.525 | 0.1449 | Yes | ||
11 | UBE2H | 1980142 2970079 | 1161 | 1.491 | 0.1566 | Yes | ||
12 | MAP4K2 | 4200037 | 1181 | 1.482 | 0.1696 | Yes | ||
13 | CCL5 | 3710397 | 1229 | 1.453 | 0.1807 | Yes | ||
14 | BFSP1 | 1410347 | 1232 | 1.450 | 0.1943 | Yes | ||
15 | BCKDK | 1940601 3990600 | 1258 | 1.428 | 0.2064 | Yes | ||
16 | IRF1 | 2340152 3450592 6290121 6980577 | 1313 | 1.388 | 0.2165 | Yes | ||
17 | TRIB2 | 4120605 | 1435 | 1.321 | 0.2224 | Yes | ||
18 | AGPAT1 | 610056 | 1464 | 1.298 | 0.2331 | Yes | ||
19 | RPS6KA4 | 2190524 | 1491 | 1.271 | 0.2437 | Yes | ||
20 | JAK3 | 70347 3290008 | 1508 | 1.262 | 0.2547 | Yes | ||
21 | EBI3 | 5340300 | 1649 | 1.172 | 0.2581 | Yes | ||
22 | ABHD8 | 6660082 | 1691 | 1.150 | 0.2667 | Yes | ||
23 | PFN1 | 6130132 | 1701 | 1.144 | 0.2770 | Yes | ||
24 | RRAS | 4150609 | 1766 | 1.094 | 0.2839 | Yes | ||
25 | STAT6 | 1190010 5720019 | 1810 | 1.075 | 0.2917 | Yes | ||
26 | NFKB2 | 2320670 | 1817 | 1.069 | 0.3014 | Yes | ||
27 | LTB | 3990672 | 1925 | 1.016 | 0.3052 | Yes | ||
28 | MSC | 5080139 | 1953 | 1.005 | 0.3132 | Yes | ||
29 | TAZ | 7100193 | 2030 | 0.983 | 0.3183 | Yes | ||
30 | PLAU | 6510047 | 2031 | 0.982 | 0.3276 | Yes | ||
31 | COL16A1 | 1780520 | 2051 | 0.973 | 0.3357 | Yes | ||
32 | ENO3 | 5270136 | 2060 | 0.967 | 0.3444 | Yes | ||
33 | EDG5 | 2640300 | 2137 | 0.930 | 0.3490 | Yes | ||
34 | HCST | 2350603 | 2256 | 0.874 | 0.3509 | Yes | ||
35 | CLCN1 | 840161 | 2292 | 0.858 | 0.3570 | Yes | ||
36 | VCAM1 | 2900450 | 2305 | 0.852 | 0.3644 | Yes | ||
37 | ZBTB5 | 770279 | 2362 | 0.827 | 0.3692 | Yes | ||
38 | GADD45B | 2350408 | 2500 | 0.766 | 0.3690 | Yes | ||
39 | LIG1 | 1980438 4540112 5570609 | 2526 | 0.754 | 0.3747 | Yes | ||
40 | STC2 | 4920601 | 2540 | 0.749 | 0.3811 | Yes | ||
41 | NFKBIB | 2260167 | 2552 | 0.743 | 0.3875 | Yes | ||
42 | CD83 | 4150242 | 2563 | 0.739 | 0.3939 | Yes | ||
43 | KRTAP13-1 | 2600242 | 2722 | 0.662 | 0.3916 | Yes | ||
44 | ASH1L | 2510402 5360687 6650685 | 2746 | 0.652 | 0.3965 | Yes | ||
45 | PPARBP | 4280131 5690022 5860050 | 2928 | 0.591 | 0.3922 | Yes | ||
46 | GPHN | 3290195 3840121 | 3009 | 0.562 | 0.3932 | Yes | ||
47 | ITGB4 | 1740021 3840482 | 3030 | 0.552 | 0.3973 | Yes | ||
48 | TNIP1 | 2510279 5900041 6510435 | 3126 | 0.519 | 0.3970 | Yes | ||
49 | TNFRSF1B | 3990035 5860372 | 3152 | 0.510 | 0.4005 | Yes | ||
50 | MMP9 | 580338 | 3236 | 0.483 | 0.4005 | Yes | ||
51 | CDK6 | 4920253 | 3281 | 0.469 | 0.4025 | Yes | ||
52 | ACTN3 | 3140541 6480598 | 3308 | 0.461 | 0.4055 | Yes | ||
53 | TP53 | 6130707 | 3380 | 0.442 | 0.4058 | Yes | ||
54 | MAG | 2370037 | 3491 | 0.419 | 0.4038 | No | ||
55 | DDR1 | 2060044 5220180 | 3529 | 0.411 | 0.4056 | No | ||
56 | DCAMKL1 | 540095 2690092 | 3720 | 0.369 | 0.3988 | No | ||
57 | PRX | 2260400 4200347 | 3900 | 0.338 | 0.3923 | No | ||
58 | ZFP36L2 | 510180 | 3954 | 0.328 | 0.3925 | No | ||
59 | SLAMF8 | 1230048 | 4059 | 0.310 | 0.3898 | No | ||
60 | PCSK2 | 360017 430528 5900619 | 4186 | 0.287 | 0.3856 | No | ||
61 | TRIM47 | 5080717 | 4213 | 0.283 | 0.3869 | No | ||
62 | COL11A2 | 5130341 | 4276 | 0.274 | 0.3861 | No | ||
63 | SOX5 | 2370576 2900167 3190128 5050528 | 4329 | 0.268 | 0.3858 | No | ||
64 | RND1 | 5080300 | 4369 | 0.264 | 0.3862 | No | ||
65 | CXCL9 | 1570673 | 4438 | 0.253 | 0.3849 | No | ||
66 | IL13 | 7040021 | 4590 | 0.235 | 0.3789 | No | ||
67 | TNFSF18 | 1990458 2850520 | 4690 | 0.222 | 0.3756 | No | ||
68 | SLC12A2 | 4610019 6040672 | 4813 | 0.210 | 0.3710 | No | ||
69 | CXCL2 | 610398 | 4866 | 0.205 | 0.3701 | No | ||
70 | GRK5 | 1940348 4670053 | 5015 | 0.190 | 0.3639 | No | ||
71 | FUT7 | 2900736 | 5196 | 0.173 | 0.3557 | No | ||
72 | NOL4 | 5050446 5360519 | 5230 | 0.171 | 0.3555 | No | ||
73 | DAP3 | 1660528 2120039 5420593 | 5490 | 0.151 | 0.3429 | No | ||
74 | HSD3B7 | 1410129 | 5597 | 0.143 | 0.3385 | No | ||
75 | TNFRSF9 | 2510400 6650484 | 5701 | 0.137 | 0.3342 | No | ||
76 | KCNH3 | 3130100 | 5721 | 0.135 | 0.3345 | No | ||
77 | CTGF | 4540577 | 5729 | 0.135 | 0.3353 | No | ||
78 | BMP2K | 60541 5570504 | 5753 | 0.133 | 0.3354 | No | ||
79 | CPD | 5360403 5860685 | 5802 | 0.130 | 0.3340 | No | ||
80 | SMPD3 | 520164 | 5815 | 0.130 | 0.3346 | No | ||
81 | MOBKL2C | 2640088 3830017 | 5948 | 0.122 | 0.3285 | No | ||
82 | BCL6B | 60047 | 5968 | 0.121 | 0.3286 | No | ||
83 | RIMS2 | 670725 | 6021 | 0.119 | 0.3269 | No | ||
84 | IL1A | 3610056 | 6048 | 0.117 | 0.3266 | No | ||
85 | IFNB1 | 1400142 | 6317 | 0.104 | 0.3131 | No | ||
86 | PUNC | 2470647 | 6428 | 0.098 | 0.3080 | No | ||
87 | SP6 | 60484 510452 2690333 | 6486 | 0.096 | 0.3058 | No | ||
88 | C1QL1 | 2030465 | 6724 | 0.086 | 0.2938 | No | ||
89 | LTA | 1740088 | 6769 | 0.085 | 0.2922 | No | ||
90 | FTHL17 | 6550193 | 6883 | 0.080 | 0.2868 | No | ||
91 | GABRB1 | 6760193 | 6992 | 0.076 | 0.2817 | No | ||
92 | IER5 | 2350575 | 7003 | 0.076 | 0.2819 | No | ||
93 | MAP3K8 | 2940286 | 7203 | 0.070 | 0.2717 | No | ||
94 | TSLP | 730408 1990500 | 7256 | 0.069 | 0.2696 | No | ||
95 | ZBTB11 | 6520092 | 7317 | 0.067 | 0.2669 | No | ||
96 | ATOH1 | 460278 | 7493 | 0.062 | 0.2580 | No | ||
97 | HSD11B2 | 5900053 | 7629 | 0.058 | 0.2513 | No | ||
98 | TNFSF15 | 360341 | 7718 | 0.056 | 0.2470 | No | ||
99 | BNC2 | 4810603 | 7719 | 0.056 | 0.2475 | No | ||
100 | IL27 | 1990324 | 7737 | 0.056 | 0.2471 | No | ||
101 | NTN1 | 5700600 | 7807 | 0.054 | 0.2439 | No | ||
102 | ALG6 | 4060131 | 7848 | 0.053 | 0.2422 | No | ||
103 | CXCL5 | 6370333 | 7983 | 0.050 | 0.2354 | No | ||
104 | FGF1 | 4780435 5670601 | 8344 | 0.041 | 0.2163 | No | ||
105 | GATA4 | 1410215 2690609 | 8583 | 0.037 | 0.2037 | No | ||
106 | HOXB9 | 2640687 | 8757 | 0.033 | 0.1947 | No | ||
107 | HOXA11 | 6980133 | 8863 | 0.031 | 0.1893 | No | ||
108 | GREM1 | 3940180 | 8894 | 0.030 | 0.1879 | No | ||
109 | FKHL18 | 6370603 | 9056 | 0.028 | 0.1794 | No | ||
110 | SLC6A12 | 3170685 | 9664 | 0.018 | 0.1467 | No | ||
111 | TLX1 | 2630162 | 9731 | 0.016 | 0.1432 | No | ||
112 | CXCL10 | 2450408 | 9764 | 0.016 | 0.1417 | No | ||
113 | FLRT1 | 4540348 | 9819 | 0.015 | 0.1389 | No | ||
114 | CHX10 | 3830184 | 9896 | 0.014 | 0.1349 | No | ||
115 | ARHGAP5 | 2510619 3360035 | 9961 | 0.013 | 0.1315 | No | ||
116 | EHF | 4560088 | 9970 | 0.012 | 0.1312 | No | ||
117 | RIN2 | 2450184 | 10293 | 0.007 | 0.1138 | No | ||
118 | MSX1 | 2650309 | 10361 | 0.006 | 0.1102 | No | ||
119 | KCNS3 | 4150039 | 10523 | 0.003 | 0.1015 | No | ||
120 | MADCAM1 | 1580010 | 10557 | 0.003 | 0.0998 | No | ||
121 | IL1RN | 2370333 | 10640 | 0.001 | 0.0953 | No | ||
122 | LAMA1 | 1770594 | 10719 | 0.000 | 0.0911 | No | ||
123 | IL23A | 6290044 | 11513 | -0.013 | 0.0482 | No | ||
124 | AP1S2 | 780279 4280707 | 11658 | -0.016 | 0.0405 | No | ||
125 | SALL1 | 5420020 7050195 | 11661 | -0.016 | 0.0406 | No | ||
126 | GNAO1 | 2510292 6590487 | 11847 | -0.020 | 0.0307 | No | ||
127 | BDNF | 2940128 3520368 | 12660 | -0.038 | -0.0130 | No | ||
128 | UBE2I | 2680056 6350446 | 12954 | -0.047 | -0.0284 | No | ||
129 | NR2F2 | 3170609 3310577 | 12988 | -0.048 | -0.0298 | No | ||
130 | BAI2 | 380632 630113 6650170 | 13080 | -0.051 | -0.0342 | No | ||
131 | CXCL11 | 1090551 | 13406 | -0.063 | -0.0513 | No | ||
132 | KCNN3 | 6520600 6420138 | 13538 | -0.069 | -0.0577 | No | ||
133 | EDN2 | 6760647 | 13676 | -0.076 | -0.0644 | No | ||
134 | GRIN2D | 6620372 | 13825 | -0.083 | -0.0717 | No | ||
135 | GNG4 | 2630600 | 13846 | -0.085 | -0.0720 | No | ||
136 | UBD | 5570632 | 13863 | -0.086 | -0.0720 | No | ||
137 | CHD4 | 5420059 6130338 6380717 | 13979 | -0.093 | -0.0774 | No | ||
138 | FGF17 | 3130022 | 14165 | -0.106 | -0.0864 | No | ||
139 | TAL1 | 7040239 | 14170 | -0.106 | -0.0856 | No | ||
140 | TRAF4 | 3060041 4920528 6980286 | 14195 | -0.107 | -0.0859 | No | ||
141 | KLK9 | 4120164 | 14207 | -0.109 | -0.0855 | No | ||
142 | WNT10B | 510050 | 14270 | -0.114 | -0.0878 | No | ||
143 | WNT10A | 2100706 | 14347 | -0.122 | -0.0908 | No | ||
144 | BIRC3 | 6550411 | 14380 | -0.125 | -0.0913 | No | ||
145 | SOX10 | 6200538 | 14522 | -0.137 | -0.0977 | No | ||
146 | JARID2 | 6290538 | 14566 | -0.141 | -0.0987 | No | ||
147 | ERN1 | 2360403 | 14585 | -0.143 | -0.0983 | No | ||
148 | ASCL3 | 4570484 | 14627 | -0.149 | -0.0991 | No | ||
149 | SESN2 | 2370019 | 14971 | -0.198 | -0.1159 | No | ||
150 | NLK | 2030010 2450041 | 15161 | -0.233 | -0.1239 | No | ||
151 | HIVEP1 | 3850632 | 15209 | -0.245 | -0.1242 | No | ||
152 | BLR1 | 1500300 5420017 | 15275 | -0.256 | -0.1253 | No | ||
153 | SHOX2 | 3190438 6450059 | 15383 | -0.282 | -0.1284 | No | ||
154 | FOXJ2 | 2450441 | 15507 | -0.310 | -0.1322 | No | ||
155 | SAMSN1 | 2370563 | 15658 | -0.354 | -0.1370 | No | ||
156 | TCEA2 | 6370546 | 15714 | -0.373 | -0.1365 | No | ||
157 | CREB1 | 1500717 2230358 3610600 6550601 | 15718 | -0.374 | -0.1331 | No | ||
158 | GNB1 | 2120397 | 15975 | -0.459 | -0.1427 | No | ||
159 | USP52 | 3710215 6380133 | 16107 | -0.502 | -0.1450 | No | ||
160 | EGF | 5220154 | 16142 | -0.515 | -0.1420 | No | ||
161 | SEC14L2 | 2640370 | 16453 | -0.638 | -0.1528 | No | ||
162 | TNF | 6650603 | 16480 | -0.652 | -0.1481 | No | ||
163 | SMOC1 | 840039 | 16510 | -0.670 | -0.1434 | No | ||
164 | BMF | 610102 | 16518 | -0.672 | -0.1374 | No | ||
165 | P2RY10 | 6370039 6840204 | 16644 | -0.740 | -0.1372 | No | ||
166 | RALGDS | 430463 | 16664 | -0.757 | -0.1311 | No | ||
167 | NFAT5 | 2510411 5890195 6550152 | 16745 | -0.804 | -0.1279 | No | ||
168 | UBE4B | 780008 3610154 | 16887 | -0.888 | -0.1272 | No | ||
169 | RBMS1 | 6400014 | 16951 | -0.929 | -0.1218 | No | ||
170 | CDC14A | 4050132 | 16977 | -0.950 | -0.1142 | No | ||
171 | PCBP4 | 6350722 | 17053 | -0.991 | -0.1090 | No | ||
172 | ICAM1 | 6980138 | 17164 | -1.039 | -0.1051 | No | ||
173 | BCL3 | 3990440 | 17204 | -1.061 | -0.0973 | No | ||
174 | CYLD | 6590079 | 17461 | -1.276 | -0.0991 | No | ||
175 | ATP1B1 | 3130594 | 17741 | -1.572 | -0.0994 | No | ||
176 | SDC4 | 6370411 | 17863 | -1.694 | -0.0900 | No | ||
177 | UACA | 1190725 | 17874 | -1.708 | -0.0745 | No | ||
178 | ARPC2 | 6020484 | 17954 | -1.788 | -0.0619 | No | ||
179 | RAP2C | 1690132 | 18028 | -1.868 | -0.0483 | No | ||
180 | UBE2D3 | 3190452 | 18074 | -1.915 | -0.0327 | No | ||
181 | MSN | 4060044 | 18102 | -1.972 | -0.0156 | No | ||
182 | HCFC1 | 2260008 | 18153 | -2.041 | 0.0009 | No | ||
183 | SIN3A | 2190121 | 18425 | -2.561 | 0.0104 | No |