Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | V$LFA1_Q6 |
Enrichment Score (ES) | 0.45142037 |
Normalized Enrichment Score (NES) | 1.3105319 |
Nominal p-value | 0.021802325 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | POLD4 | 2320082 | 55 | 3.377 | 0.0283 | Yes | ||
2 | IFRD2 | 4150110 | 63 | 3.299 | 0.0584 | Yes | ||
3 | RHOG | 6760575 | 84 | 3.188 | 0.0868 | Yes | ||
4 | CEBPB | 2970019 | 175 | 2.781 | 0.1077 | Yes | ||
5 | HES1 | 4810280 | 269 | 2.504 | 0.1258 | Yes | ||
6 | HEBP1 | 6100279 | 400 | 2.276 | 0.1398 | Yes | ||
7 | TCF7 | 3800736 5390181 | 408 | 2.262 | 0.1603 | Yes | ||
8 | BAX | 3830008 | 416 | 2.252 | 0.1808 | Yes | ||
9 | SMAD3 | 6450671 | 421 | 2.238 | 0.2013 | Yes | ||
10 | ZFP36 | 2030605 | 482 | 2.159 | 0.2180 | Yes | ||
11 | PDLIM7 | 4780136 | 624 | 1.999 | 0.2289 | Yes | ||
12 | CNN2 | 2230433 5270446 | 706 | 1.904 | 0.2421 | Yes | ||
13 | NCDN | 50040 1980739 3520603 | 745 | 1.864 | 0.2573 | Yes | ||
14 | NDUFS2 | 4850020 6200402 | 837 | 1.771 | 0.2687 | Yes | ||
15 | MAZ | 3360121 6940750 | 849 | 1.755 | 0.2844 | Yes | ||
16 | SLC25A29 | 5080095 | 984 | 1.632 | 0.2922 | Yes | ||
17 | COX7A2L | 1500142 | 996 | 1.621 | 0.3066 | Yes | ||
18 | RASGRP2 | 2970333 | 1071 | 1.563 | 0.3170 | Yes | ||
19 | PPP1R16A | 5080239 | 1260 | 1.428 | 0.3200 | Yes | ||
20 | MRPL40 | 2370215 | 1269 | 1.424 | 0.3328 | Yes | ||
21 | DCTN1 | 1450056 6590022 | 1295 | 1.405 | 0.3444 | Yes | ||
22 | ROM1 | 3130685 | 1342 | 1.373 | 0.3546 | Yes | ||
23 | GSS | 6130465 6900398 | 1478 | 1.284 | 0.3592 | Yes | ||
24 | ADM | 4810121 | 1505 | 1.264 | 0.3695 | Yes | ||
25 | RAB4B | 1770204 | 1603 | 1.205 | 0.3754 | Yes | ||
26 | MNT | 4920575 | 1607 | 1.202 | 0.3863 | Yes | ||
27 | SESN3 | 110687 | 1635 | 1.181 | 0.3958 | Yes | ||
28 | VASP | 7050500 | 1695 | 1.147 | 0.4032 | Yes | ||
29 | NFKBIA | 1570152 | 1757 | 1.101 | 0.4101 | Yes | ||
30 | PDYN | 5720408 | 1962 | 1.003 | 0.4083 | Yes | ||
31 | EPHB2 | 1090288 1410377 2100541 | 1989 | 0.997 | 0.4161 | Yes | ||
32 | IMMT | 870450 4280438 | 2005 | 0.993 | 0.4245 | Yes | ||
33 | NEURL | 5390538 | 2073 | 0.962 | 0.4298 | Yes | ||
34 | LAG3 | 6860112 | 2175 | 0.911 | 0.4327 | Yes | ||
35 | EFNA3 | 6370390 | 2182 | 0.907 | 0.4408 | Yes | ||
36 | HIRA | 4480609 5270167 | 2222 | 0.892 | 0.4469 | Yes | ||
37 | CIC | 6370161 | 2287 | 0.861 | 0.4514 | Yes | ||
38 | GABARAP | 1450286 | 2771 | 0.640 | 0.4311 | No | ||
39 | UQCRC1 | 520053 | 2820 | 0.627 | 0.4343 | No | ||
40 | MCRS1 | 110121 2340592 5270484 | 2868 | 0.610 | 0.4374 | No | ||
41 | TRIP10 | 460438 | 2910 | 0.596 | 0.4407 | No | ||
42 | SLC26A9 | 3440722 5340088 7510093 | 3244 | 0.481 | 0.4271 | No | ||
43 | STOML2 | 1940487 | 3310 | 0.461 | 0.4279 | No | ||
44 | SLC13A5 | 5810615 | 3655 | 0.384 | 0.4128 | No | ||
45 | MOV10 | 50673 430577 3870280 | 3758 | 0.362 | 0.4106 | No | ||
46 | SH3BP1 | 3450075 6350288 | 3793 | 0.354 | 0.4120 | No | ||
47 | GABRG2 | 2350402 4210204 6130279 6550037 | 3833 | 0.348 | 0.4131 | No | ||
48 | TITF1 | 3390554 4540292 | 3844 | 0.346 | 0.4158 | No | ||
49 | KIF1C | 2480484 | 3984 | 0.323 | 0.4112 | No | ||
50 | RHO | 4280398 | 3986 | 0.323 | 0.4142 | No | ||
51 | TBR1 | 5130053 | 4127 | 0.297 | 0.4093 | No | ||
52 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 4251 | 0.276 | 0.4052 | No | ||
53 | SOX5 | 2370576 2900167 3190128 5050528 | 4329 | 0.268 | 0.4035 | No | ||
54 | NRGN | 4280433 | 4501 | 0.244 | 0.3965 | No | ||
55 | GAD1 | 2360035 3140167 | 4529 | 0.240 | 0.3973 | No | ||
56 | ANXA4 | 1400315 | 4558 | 0.237 | 0.3979 | No | ||
57 | ZNF385 | 450176 4810358 | 4632 | 0.230 | 0.3961 | No | ||
58 | HOXC10 | 5360170 | 4767 | 0.215 | 0.3908 | No | ||
59 | MYOG | 3190672 | 4934 | 0.198 | 0.3836 | No | ||
60 | GPR3 | 2970452 | 5360 | 0.161 | 0.3621 | No | ||
61 | LCAT | 6400441 | 5702 | 0.137 | 0.3449 | No | ||
62 | CTGF | 4540577 | 5729 | 0.135 | 0.3447 | No | ||
63 | PALM | 130601 3850017 | 5798 | 0.131 | 0.3422 | No | ||
64 | RABGGTA | 3190484 4070195 | 5923 | 0.123 | 0.3366 | No | ||
65 | CREB3L2 | 3390484 | 6004 | 0.119 | 0.3334 | No | ||
66 | M6PR | 2480458 3290593 3840324 | 6129 | 0.112 | 0.3277 | No | ||
67 | POU4F1 | 2260315 | 6227 | 0.108 | 0.3235 | No | ||
68 | CACNA1G | 3060161 4810706 5550722 | 6438 | 0.098 | 0.3130 | No | ||
69 | CLIC5 | 6900338 | 6500 | 0.095 | 0.3105 | No | ||
70 | DLGAP4 | 4570672 5690161 | 6799 | 0.083 | 0.2952 | No | ||
71 | GRIN2A | 6550538 | 6902 | 0.080 | 0.2904 | No | ||
72 | ETV1 | 70735 2940603 5080463 | 6938 | 0.079 | 0.2892 | No | ||
73 | EPO | 940180 | 6955 | 0.078 | 0.2890 | No | ||
74 | TPCN1 | 60458 6510731 6860601 | 7011 | 0.076 | 0.2868 | No | ||
75 | JPH4 | 780020 | 7023 | 0.076 | 0.2869 | No | ||
76 | GBA2 | 2900372 | 7067 | 0.074 | 0.2852 | No | ||
77 | TNRC4 | 4050156 | 7129 | 0.072 | 0.2826 | No | ||
78 | ADAMTS4 | 430435 | 7310 | 0.067 | 0.2734 | No | ||
79 | HARS2 | 1400215 2640471 | 7387 | 0.065 | 0.2699 | No | ||
80 | PTRF | 2260204 | 7434 | 0.063 | 0.2680 | No | ||
81 | SEMA6A | 2690138 3060021 | 7533 | 0.061 | 0.2633 | No | ||
82 | SMARCD2 | 3830619 | 7647 | 0.058 | 0.2577 | No | ||
83 | BNC2 | 4810603 | 7719 | 0.056 | 0.2543 | No | ||
84 | NKX2-3 | 1990736 6940088 | 7720 | 0.056 | 0.2549 | No | ||
85 | USH1G | 2940446 | 7753 | 0.055 | 0.2536 | No | ||
86 | NR4A1 | 6290161 | 7795 | 0.054 | 0.2519 | No | ||
87 | NPTXR | 4060685 450438 | 7867 | 0.052 | 0.2485 | No | ||
88 | CAV1 | 870025 | 7984 | 0.050 | 0.2427 | No | ||
89 | MYBPH | 2190711 | 8026 | 0.049 | 0.2409 | No | ||
90 | DPF2 | 6980373 | 8290 | 0.043 | 0.2271 | No | ||
91 | HNRPR | 2320440 2900601 4610008 | 8572 | 0.037 | 0.2122 | No | ||
92 | NACA | 520326 5890673 | 8697 | 0.035 | 0.2058 | No | ||
93 | XYLT1 | 6550403 | 8818 | 0.032 | 0.1996 | No | ||
94 | WNT4 | 4150619 | 8861 | 0.031 | 0.1976 | No | ||
95 | RFX4 | 3710100 5340215 | 9162 | 0.026 | 0.1816 | No | ||
96 | PAK1IP1 | 2230438 | 9170 | 0.026 | 0.1814 | No | ||
97 | ACCN1 | 2060139 2190541 | 9207 | 0.025 | 0.1797 | No | ||
98 | GPR4 | 2060358 | 9350 | 0.023 | 0.1722 | No | ||
99 | ACVR1C | 5890044 | 9536 | 0.020 | 0.1624 | No | ||
100 | CHX10 | 3830184 | 9896 | 0.014 | 0.1430 | No | ||
101 | LMOD3 | 2120524 | 9969 | 0.012 | 0.1392 | No | ||
102 | OTOP2 | 610068 | 9999 | 0.012 | 0.1378 | No | ||
103 | RAB5C | 1990397 | 10140 | 0.009 | 0.1303 | No | ||
104 | MGEA5 | 6100014 | 10157 | 0.009 | 0.1295 | No | ||
105 | DUOX2 | 1410575 | 10266 | 0.007 | 0.1237 | No | ||
106 | BOC | 5270348 | 10352 | 0.006 | 0.1191 | No | ||
107 | MSX1 | 2650309 | 10361 | 0.006 | 0.1187 | No | ||
108 | PPY | 2340373 | 10385 | 0.005 | 0.1176 | No | ||
109 | EDG1 | 4200619 | 10622 | 0.002 | 0.1048 | No | ||
110 | AKT3 | 1580270 3290278 | 10642 | 0.001 | 0.1038 | No | ||
111 | SLC7A10 | 5570411 | 10718 | 0.000 | 0.0997 | No | ||
112 | PLA2G10 | 3060605 | 10771 | -0.001 | 0.0969 | No | ||
113 | CRMP1 | 4810014 | 10777 | -0.001 | 0.0966 | No | ||
114 | SLC2A4 | 540441 | 11569 | -0.014 | 0.0539 | No | ||
115 | SP7 | 1050315 | 11611 | -0.015 | 0.0518 | No | ||
116 | S100A5 | 4120592 | 11646 | -0.016 | 0.0501 | No | ||
117 | SALL1 | 5420020 7050195 | 11661 | -0.016 | 0.0495 | No | ||
118 | CACNB1 | 2940427 3710487 | 11679 | -0.016 | 0.0487 | No | ||
119 | GNAO1 | 2510292 6590487 | 11847 | -0.020 | 0.0398 | No | ||
120 | OLFML2A | 5890039 | 12108 | -0.025 | 0.0259 | No | ||
121 | SIX4 | 6760022 | 12181 | -0.027 | 0.0223 | No | ||
122 | THRAP1 | 2470121 | 12182 | -0.027 | 0.0225 | No | ||
123 | KCNQ4 | 3800438 7050400 | 12394 | -0.032 | 0.0114 | No | ||
124 | CLTC | 6590458 | 12416 | -0.032 | 0.0105 | No | ||
125 | NEUROG1 | 380341 | 12565 | -0.035 | 0.0028 | No | ||
126 | NPAS3 | 630408 4610066 | 12607 | -0.037 | 0.0010 | No | ||
127 | LIN28 | 6590672 | 12802 | -0.042 | -0.0092 | No | ||
128 | TSP50 | 6100593 | 12963 | -0.047 | -0.0174 | No | ||
129 | NGFB | 2630019 | 13146 | -0.054 | -0.0268 | No | ||
130 | NYX | 4120239 | 13316 | -0.060 | -0.0354 | No | ||
131 | CASQ2 | 3170136 | 13345 | -0.061 | -0.0363 | No | ||
132 | FLT1 | 3830167 4920438 | 13505 | -0.068 | -0.0443 | No | ||
133 | DHH | 2120433 | 13614 | -0.073 | -0.0495 | No | ||
134 | IL1F10 | 2260647 | 13672 | -0.076 | -0.0519 | No | ||
135 | OBSCN | 3610129 | 13857 | -0.085 | -0.0611 | No | ||
136 | FXYD3 | 2320450 | 13981 | -0.093 | -0.0669 | No | ||
137 | PAX7 | 6860593 | 14122 | -0.102 | -0.0735 | No | ||
138 | TAL1 | 7040239 | 14170 | -0.106 | -0.0751 | No | ||
139 | HOXC6 | 3850133 4920736 | 14175 | -0.106 | -0.0743 | No | ||
140 | KLK9 | 4120164 | 14207 | -0.109 | -0.0750 | No | ||
141 | KCNAB1 | 1580070 3290156 | 14240 | -0.112 | -0.0757 | No | ||
142 | LRP8 | 3610746 5360035 | 14368 | -0.123 | -0.0815 | No | ||
143 | PRRX1 | 4120193 4480390 | 14623 | -0.149 | -0.0939 | No | ||
144 | CPNE1 | 3440131 | 14641 | -0.150 | -0.0934 | No | ||
145 | RBM12 | 4570239 6040411 6660129 | 14852 | -0.179 | -0.1031 | No | ||
146 | CNKSR2 | 110348 1770372 | 14878 | -0.183 | -0.1028 | No | ||
147 | ARID4A | 520156 1050707 | 14880 | -0.183 | -0.1012 | No | ||
148 | BRPF1 | 3170139 | 15112 | -0.224 | -0.1116 | No | ||
149 | NR5A2 | 1690180 6900050 | 15122 | -0.226 | -0.1100 | No | ||
150 | PNOC | 1990114 | 15473 | -0.300 | -0.1262 | No | ||
151 | PHF12 | 870400 3130687 | 15491 | -0.306 | -0.1243 | No | ||
152 | ELF4 | 4850193 | 15581 | -0.330 | -0.1261 | No | ||
153 | FKBP2 | 2320025 | 15896 | -0.434 | -0.1391 | No | ||
154 | FES | 3120129 5550600 | 16131 | -0.511 | -0.1470 | No | ||
155 | BACE1 | 2650438 | 16341 | -0.592 | -0.1529 | No | ||
156 | LZTS2 | 2260440 | 16443 | -0.635 | -0.1525 | No | ||
157 | CKB | 4560632 | 16445 | -0.636 | -0.1467 | No | ||
158 | RBBP6 | 2320129 | 16474 | -0.650 | -0.1422 | No | ||
159 | PCBP2 | 5690048 | 16524 | -0.675 | -0.1386 | No | ||
160 | CXCR4 | 4590519 | 16552 | -0.686 | -0.1337 | No | ||
161 | NFAT5 | 2510411 5890195 6550152 | 16745 | -0.804 | -0.1367 | No | ||
162 | GSK3B | 5360348 | 17269 | -1.119 | -0.1547 | No | ||
163 | DLX1 | 360168 | 17318 | -1.151 | -0.1466 | No | ||
164 | FLI1 | 3990142 | 17449 | -1.266 | -0.1420 | No | ||
165 | PYGO2 | 360494 | 17505 | -1.326 | -0.1327 | No | ||
166 | NPC2 | 2350102 | 17717 | -1.546 | -0.1298 | No | ||
167 | BCL11B | 2680673 | 17870 | -1.704 | -0.1223 | No | ||
168 | CCNL1 | 130273 | 17942 | -1.776 | -0.1097 | No | ||
169 | UPF2 | 4810471 | 17962 | -1.793 | -0.0942 | No | ||
170 | ZFPM1 | 6760093 | 18013 | -1.858 | -0.0797 | No | ||
171 | NXF1 | 1570377 | 18162 | -2.053 | -0.0687 | No | ||
172 | BCL6 | 940100 | 18261 | -2.213 | -0.0536 | No | ||
173 | UBL3 | 6450458 | 18289 | -2.259 | -0.0341 | No | ||
174 | EMILIN1 | 2190402 | 18438 | -2.597 | -0.0181 | No | ||
175 | ARID1A | 2630022 1690551 4810110 | 18538 | -2.995 | 0.0042 | No |