Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | V$E12_Q6 |
Enrichment Score (ES) | 0.44777972 |
Normalized Enrichment Score (NES) | 1.3217353 |
Nominal p-value | 0.020028612 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | GNAS | 630441 1850373 4050152 | 32 | 3.653 | 0.0369 | Yes | ||
2 | PTK2B | 4730411 | 40 | 3.507 | 0.0735 | Yes | ||
3 | AIG1 | 2450091 | 58 | 3.339 | 0.1079 | Yes | ||
4 | HEYL | 5860528 | 64 | 3.298 | 0.1425 | Yes | ||
5 | ELOVL1 | 2450019 4760138 5340685 | 123 | 2.949 | 0.1705 | Yes | ||
6 | PPOX | 2640678 3850102 | 352 | 2.364 | 0.1831 | Yes | ||
7 | SMAD3 | 6450671 | 421 | 2.238 | 0.2031 | Yes | ||
8 | SASH1 | 4070270 | 456 | 2.190 | 0.2243 | Yes | ||
9 | GFRA1 | 3610152 | 461 | 2.182 | 0.2472 | Yes | ||
10 | SELL | 1190500 | 673 | 1.940 | 0.2562 | Yes | ||
11 | SLC37A4 | 6400079 | 702 | 1.909 | 0.2749 | Yes | ||
12 | HMGA1 | 6580408 | 787 | 1.825 | 0.2896 | Yes | ||
13 | TNFSF13 | 2650170 | 927 | 1.692 | 0.3000 | Yes | ||
14 | HES6 | 540411 6550504 | 1013 | 1.605 | 0.3123 | Yes | ||
15 | PSTPIP1 | 3190156 | 1216 | 1.463 | 0.3168 | Yes | ||
16 | ARID5A | 2450133 | 1221 | 1.460 | 0.3320 | Yes | ||
17 | IGF2 | 6510020 | 1271 | 1.422 | 0.3444 | Yes | ||
18 | TTC17 | 2470440 | 1335 | 1.376 | 0.3555 | Yes | ||
19 | CKM | 1450524 | 1381 | 1.346 | 0.3673 | Yes | ||
20 | CENTB1 | 2120093 | 1388 | 1.343 | 0.3812 | Yes | ||
21 | GPD1 | 2480095 | 1544 | 1.243 | 0.3859 | Yes | ||
22 | IGSF8 | 1580592 | 1627 | 1.185 | 0.3940 | Yes | ||
23 | RANGAP1 | 2320593 6650601 | 1814 | 1.071 | 0.3952 | Yes | ||
24 | ARHGAP24 | 540278 4540025 | 1990 | 0.996 | 0.3962 | Yes | ||
25 | POLR1D | 70082 450750 6040458 | 2017 | 0.990 | 0.4053 | Yes | ||
26 | CORO2A | 3840605 6620390 | 2041 | 0.976 | 0.4143 | Yes | ||
27 | ENO3 | 5270136 | 2060 | 0.967 | 0.4236 | Yes | ||
28 | NEURL | 5390538 | 2073 | 0.962 | 0.4331 | Yes | ||
29 | GRB7 | 2100471 | 2196 | 0.901 | 0.4360 | Yes | ||
30 | DEF6 | 840593 | 2389 | 0.811 | 0.4342 | Yes | ||
31 | STC2 | 4920601 | 2540 | 0.749 | 0.4339 | Yes | ||
32 | CRELD1 | 2060253 | 2605 | 0.718 | 0.4381 | Yes | ||
33 | SIPA1 | 5220687 | 2672 | 0.687 | 0.4417 | Yes | ||
34 | INVS | 4200632 6620528 | 2704 | 0.671 | 0.4471 | Yes | ||
35 | IGFBP5 | 2360592 | 2913 | 0.595 | 0.4422 | Yes | ||
36 | TNFRSF21 | 6380100 | 2983 | 0.570 | 0.4444 | Yes | ||
37 | ITGB4 | 1740021 3840482 | 3030 | 0.552 | 0.4478 | Yes | ||
38 | CXCL14 | 840114 6450324 | 3223 | 0.488 | 0.4425 | No | ||
39 | ACTN3 | 3140541 6480598 | 3308 | 0.461 | 0.4428 | No | ||
40 | SYT4 | 5080193 | 3357 | 0.448 | 0.4450 | No | ||
41 | SEMA3F | 5420601 6770731 | 3708 | 0.372 | 0.4299 | No | ||
42 | USP2 | 1190292 1240253 4850035 | 3732 | 0.367 | 0.4325 | No | ||
43 | POFUT1 | 1570458 | 3790 | 0.354 | 0.4332 | No | ||
44 | FGF8 | 6350504 | 3853 | 0.346 | 0.4335 | No | ||
45 | SCG2 | 5670438 130671 | 3858 | 0.345 | 0.4369 | No | ||
46 | LRP5 | 2100397 3170484 | 4138 | 0.295 | 0.4249 | No | ||
47 | PHACTR3 | 3850435 5900445 | 4214 | 0.282 | 0.4238 | No | ||
48 | DNAJB5 | 2900215 | 4249 | 0.277 | 0.4249 | No | ||
49 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 4251 | 0.276 | 0.4278 | No | ||
50 | BRUNOL4 | 4490452 5080451 | 4292 | 0.272 | 0.4285 | No | ||
51 | MDGA1 | 1170139 | 4321 | 0.269 | 0.4298 | No | ||
52 | FYN | 2100468 4760520 4850687 | 4389 | 0.260 | 0.4289 | No | ||
53 | GGN | 1410528 4210082 5290170 | 4466 | 0.249 | 0.4274 | No | ||
54 | HOXB7 | 4540706 4610358 | 4561 | 0.237 | 0.4248 | No | ||
55 | PLCB3 | 4670402 | 4661 | 0.227 | 0.4219 | No | ||
56 | PRKAG2 | 2340100 | 4712 | 0.220 | 0.4215 | No | ||
57 | TNNC2 | 3840079 | 4963 | 0.195 | 0.4100 | No | ||
58 | CANX | 4760402 | 5045 | 0.187 | 0.4076 | No | ||
59 | NOL4 | 5050446 5360519 | 5230 | 0.171 | 0.3994 | No | ||
60 | CDH2 | 520435 2450451 2760025 6650477 | 5313 | 0.164 | 0.3967 | No | ||
61 | DNMT3A | 4050068 4810717 | 5565 | 0.146 | 0.3846 | No | ||
62 | DLL1 | 1770377 | 5744 | 0.134 | 0.3764 | No | ||
63 | TEAD4 | 1850239 6380519 | 5925 | 0.123 | 0.3679 | No | ||
64 | FSCN2 | 1230039 | 6073 | 0.115 | 0.3612 | No | ||
65 | POU2F3 | 2030601 | 6096 | 0.114 | 0.3612 | No | ||
66 | CALB1 | 460070 | 6326 | 0.103 | 0.3498 | No | ||
67 | CYP26A1 | 380022 2690600 | 6524 | 0.094 | 0.3401 | No | ||
68 | CHST9 | 4560092 | 6653 | 0.089 | 0.3341 | No | ||
69 | KCNK12 | 4070072 | 6730 | 0.086 | 0.3309 | No | ||
70 | MT3 | 1450537 | 6738 | 0.086 | 0.3315 | No | ||
71 | RASSF2 | 2480079 5720546 | 6822 | 0.083 | 0.3278 | No | ||
72 | IRX6 | 4590025 | 7184 | 0.071 | 0.3090 | No | ||
73 | GJB2 | 5900609 6200487 | 7273 | 0.068 | 0.3050 | No | ||
74 | CPZ | 70193 | 7315 | 0.067 | 0.3034 | No | ||
75 | SLC24A3 | 5080707 | 7318 | 0.067 | 0.3040 | No | ||
76 | HSD11B2 | 5900053 | 7629 | 0.058 | 0.2878 | No | ||
77 | ANK2 | 6510546 | 7637 | 0.058 | 0.2881 | No | ||
78 | MYOZ3 | 1990138 | 7707 | 0.056 | 0.2849 | No | ||
79 | NR4A1 | 6290161 | 7795 | 0.054 | 0.2808 | No | ||
80 | CALN1 | 3610722 | 7896 | 0.052 | 0.2759 | No | ||
81 | PPP1R9B | 3130619 | 7938 | 0.051 | 0.2742 | No | ||
82 | ROBO3 | 6550408 | 7948 | 0.051 | 0.2743 | No | ||
83 | ODC1 | 5670168 | 8038 | 0.048 | 0.2699 | No | ||
84 | RTN4RL2 | 6450609 | 8091 | 0.047 | 0.2676 | No | ||
85 | ALDH1A2 | 2320301 | 8225 | 0.044 | 0.2609 | No | ||
86 | CENTG3 | 2470079 4610092 5050170 | 8325 | 0.042 | 0.2560 | No | ||
87 | GDPD2 | 7000040 | 8380 | 0.041 | 0.2535 | No | ||
88 | CPA4 | 3610100 | 8561 | 0.037 | 0.2441 | No | ||
89 | ZNF205 | 6900022 | 8635 | 0.036 | 0.2405 | No | ||
90 | DOC2A | 6020121 | 8835 | 0.032 | 0.2300 | No | ||
91 | GATA2 | 6590280 | 8948 | 0.029 | 0.2243 | No | ||
92 | DLL3 | 4010093 | 9074 | 0.027 | 0.2178 | No | ||
93 | CORO2B | 2340035 4850390 | 9077 | 0.027 | 0.2180 | No | ||
94 | GPR37 | 2320093 | 9105 | 0.027 | 0.2168 | No | ||
95 | GPM6B | 6220458 | 9126 | 0.027 | 0.2160 | No | ||
96 | NFATC4 | 2470735 | 9458 | 0.021 | 0.1983 | No | ||
97 | ARHGEF12 | 3990195 | 9615 | 0.018 | 0.1900 | No | ||
98 | SFTPC | 3290133 | 9719 | 0.016 | 0.1846 | No | ||
99 | SOST | 1170195 | 9817 | 0.015 | 0.1795 | No | ||
100 | ARVCF | 2190537 | 9954 | 0.013 | 0.1722 | No | ||
101 | MTUS1 | 780348 4920609 | 9973 | 0.012 | 0.1714 | No | ||
102 | CHRND | 840403 2260670 | 10099 | 0.010 | 0.1647 | No | ||
103 | FOXI1 | 3710095 6620195 | 10240 | 0.008 | 0.1572 | No | ||
104 | PPARA | 2060026 | 10473 | 0.004 | 0.1447 | No | ||
105 | KCNB1 | 3610035 | 10551 | 0.003 | 0.1405 | No | ||
106 | CCNL2 | 6520167 | 10655 | 0.001 | 0.1350 | No | ||
107 | PTPRJ | 4010707 | 10982 | -0.004 | 0.1173 | No | ||
108 | BMP6 | 2100128 | 11287 | -0.009 | 0.1009 | No | ||
109 | FGF11 | 840292 | 11320 | -0.010 | 0.0993 | No | ||
110 | SORCS2 | 6350520 | 11377 | -0.011 | 0.0964 | No | ||
111 | NHLH1 | 6100452 | 11425 | -0.012 | 0.0939 | No | ||
112 | SLC12A5 | 1980692 | 11657 | -0.016 | 0.0816 | No | ||
113 | AP1S2 | 780279 4280707 | 11658 | -0.016 | 0.0818 | No | ||
114 | HIF3A | 2630053 2680102 6450364 | 11768 | -0.018 | 0.0760 | No | ||
115 | NBL1 | 2480021 | 11890 | -0.020 | 0.0697 | No | ||
116 | COL4A3 | 5910075 | 12017 | -0.023 | 0.0631 | No | ||
117 | NPEPPS | 2630731 | 12061 | -0.024 | 0.0610 | No | ||
118 | LAMA5 | 2680722 | 12078 | -0.024 | 0.0604 | No | ||
119 | TREX2 | 4920707 | 12088 | -0.025 | 0.0602 | No | ||
120 | GFAP | 2060092 | 12535 | -0.035 | 0.0364 | No | ||
121 | MYH14 | 4010017 | 12567 | -0.035 | 0.0351 | No | ||
122 | MTSS1 | 780435 2370114 | 12568 | -0.035 | 0.0354 | No | ||
123 | UNC13B | 130735 | 12661 | -0.038 | 0.0308 | No | ||
124 | GRIA1 | 1340152 3780750 4920440 | 12664 | -0.038 | 0.0311 | No | ||
125 | TCF2 | 870338 5050632 | 12683 | -0.039 | 0.0306 | No | ||
126 | PCDH15 | 7000438 | 12726 | -0.040 | 0.0287 | No | ||
127 | ANKRD2 | 6590427 | 12840 | -0.043 | 0.0230 | No | ||
128 | WTAP | 4010176 | 12992 | -0.048 | 0.0154 | No | ||
129 | NEGR1 | 1940731 5130170 | 13122 | -0.053 | 0.0089 | No | ||
130 | RAPGEF4 | 6100563 | 13211 | -0.056 | 0.0047 | No | ||
131 | KLHL13 | 6590731 | 13297 | -0.059 | 0.0007 | No | ||
132 | DSCAM | 1780050 2450731 2810438 | 13365 | -0.062 | -0.0022 | No | ||
133 | FUT8 | 1340068 2340056 | 13436 | -0.065 | -0.0053 | No | ||
134 | HR | 2690095 6200300 | 13480 | -0.067 | -0.0070 | No | ||
135 | SOX17 | 5270551 | 13488 | -0.067 | -0.0066 | No | ||
136 | KCNN3 | 6520600 6420138 | 13538 | -0.069 | -0.0086 | No | ||
137 | PIM2 | 840136 5720692 7100577 | 13685 | -0.076 | -0.0157 | No | ||
138 | RAB26 | 5910025 | 13789 | -0.082 | -0.0204 | No | ||
139 | NTRK2 | 6220463 | 13810 | -0.083 | -0.0206 | No | ||
140 | SIM1 | 1770332 | 13853 | -0.085 | -0.0220 | No | ||
141 | ELMO1 | 110338 1190451 1580148 1850609 2350706 2370369 2450129 3840113 4150184 4280079 6290066 6380435 6770494 7100180 | 13915 | -0.089 | -0.0244 | No | ||
142 | ITGA6 | 3830129 | 14095 | -0.100 | -0.0330 | No | ||
143 | COL4A4 | 1050541 | 14134 | -0.103 | -0.0340 | No | ||
144 | CHRDL1 | 1580037 6380204 | 14262 | -0.114 | -0.0397 | No | ||
145 | TNFAIP1 | 6940593 | 14280 | -0.115 | -0.0394 | No | ||
146 | ASB14 | 5860427 | 14424 | -0.128 | -0.0458 | No | ||
147 | SSH2 | 360056 | 14577 | -0.142 | -0.0525 | No | ||
148 | CNNM2 | 2650100 | 14598 | -0.145 | -0.0521 | No | ||
149 | CDH5 | 5340487 | 14636 | -0.150 | -0.0525 | No | ||
150 | EIF2C1 | 6900551 | 14773 | -0.168 | -0.0581 | No | ||
151 | WDR20 | 1240373 | 14820 | -0.174 | -0.0587 | No | ||
152 | TRIM23 | 580168 6510672 | 15095 | -0.219 | -0.0713 | No | ||
153 | ADAM12 | 3390132 4070347 | 15105 | -0.222 | -0.0694 | No | ||
154 | RIN1 | 510593 | 15195 | -0.241 | -0.0717 | No | ||
155 | CAMK1D | 1660100 2350309 | 15241 | -0.251 | -0.0715 | No | ||
156 | CAMK2A | 1740333 1940112 4150292 | 15552 | -0.322 | -0.0849 | No | ||
157 | EYA3 | 1580195 6510632 | 15636 | -0.348 | -0.0857 | No | ||
158 | PACSIN3 | 4540369 4540400 5360037 6940129 | 15695 | -0.367 | -0.0850 | No | ||
159 | TGFB3 | 1070041 | 15914 | -0.438 | -0.0922 | No | ||
160 | NTRK3 | 4050687 4070167 4610026 6100484 | 16034 | -0.477 | -0.0936 | No | ||
161 | SORT1 | 1850242 2320632 3870537 | 16382 | -0.608 | -0.1060 | No | ||
162 | WNT6 | 4570364 | 16391 | -0.610 | -0.1000 | No | ||
163 | LNX2 | 3130025 | 16447 | -0.636 | -0.0962 | No | ||
164 | GRB2 | 6650398 | 16567 | -0.690 | -0.0954 | No | ||
165 | HMGN2 | 3140091 | 16716 | -0.789 | -0.0951 | No | ||
166 | LRP10 | 1580128 | 16889 | -0.890 | -0.0950 | No | ||
167 | CFL1 | 2340735 | 16966 | -0.941 | -0.0892 | No | ||
168 | TPM3 | 670600 3170296 5670167 6650471 | 17068 | -0.998 | -0.0841 | No | ||
169 | MFNG | 1770242 4280348 | 17148 | -1.029 | -0.0775 | No | ||
170 | NUP88 | 2510044 6760180 | 17411 | -1.238 | -0.0787 | No | ||
171 | SLC23A2 | 6660722 | 17562 | -1.380 | -0.0722 | No | ||
172 | PLAGL2 | 1770148 | 17572 | -1.390 | -0.0580 | No | ||
173 | RUNX1 | 3840711 | 17706 | -1.531 | -0.0491 | No | ||
174 | OSR1 | 1500025 | 17906 | -1.738 | -0.0415 | No | ||
175 | EGLN1 | 2480180 3120253 6110195 | 18255 | -2.198 | -0.0371 | No | ||
176 | RRAGC | 5910348 | 18404 | -2.517 | -0.0186 | No | ||
177 | NEDD4L | 6380368 | 18511 | -2.841 | 0.0057 | No |