Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | wtNotch |
GeneSet | ATGTACA,MIR-493 |
Enrichment Score (ES) | -0.5780098 |
Normalized Enrichment Score (NES) | -1.8666883 |
Nominal p-value | 0.0 |
FDR q-value | 8.279061E-4 |
FWER p-Value | 0.0030 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | USP21 | 3060446 | 559 | 2.064 | -0.0153 | No | ||
2 | SLC25A26 | 4210577 | 1028 | 1.593 | -0.0290 | No | ||
3 | PMP22 | 4010239 6550072 | 1123 | 1.521 | -0.0230 | No | ||
4 | IRF7 | 1570605 | 1159 | 1.493 | -0.0140 | No | ||
5 | ANKRD50 | 870543 | 1472 | 1.290 | -0.0215 | No | ||
6 | HNRPA0 | 2680048 | 1551 | 1.239 | -0.0166 | No | ||
7 | UBE2Q1 | 610348 2350114 4210717 | 1672 | 1.161 | -0.0147 | No | ||
8 | LRIG1 | 1050136 | 1674 | 1.160 | -0.0062 | No | ||
9 | OTUB1 | 610551 | 1932 | 1.014 | -0.0128 | No | ||
10 | DOCK9 | 5080037 | 2140 | 0.930 | -0.0172 | No | ||
11 | HIC2 | 4010433 | 2150 | 0.923 | -0.0109 | No | ||
12 | EFNA3 | 6370390 | 2182 | 0.907 | -0.0060 | No | ||
13 | CRSP7 | 4230408 | 2246 | 0.877 | -0.0030 | No | ||
14 | VGLL4 | 6860463 | 2375 | 0.818 | -0.0039 | No | ||
15 | ATAD2 | 870242 2260687 | 2457 | 0.780 | -0.0026 | No | ||
16 | ATP5A1 | 1990722 | 2691 | 0.679 | -0.0103 | No | ||
17 | VAMP2 | 2100100 | 2701 | 0.674 | -0.0059 | No | ||
18 | ANTXR1 | 1990593 2850056 | 2752 | 0.649 | -0.0038 | No | ||
19 | CHKB | 770129 | 2819 | 0.627 | -0.0028 | No | ||
20 | BCL2 | 730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164 | 2962 | 0.579 | -0.0063 | No | ||
21 | TMEM16D | 2650324 | 3073 | 0.536 | -0.0084 | No | ||
22 | LRP12 | 2370112 | 3131 | 0.517 | -0.0077 | No | ||
23 | KPNA4 | 510369 | 3238 | 0.482 | -0.0099 | No | ||
24 | OVOL1 | 1690131 | 3523 | 0.412 | -0.0223 | No | ||
25 | SPRYD3 | 50403 | 3530 | 0.411 | -0.0196 | No | ||
26 | SPAG8 | 4280446 | 3697 | 0.374 | -0.0259 | No | ||
27 | FGF13 | 630575 1570440 5360121 | 3714 | 0.371 | -0.0241 | No | ||
28 | SNRP70 | 4200181 | 3783 | 0.355 | -0.0252 | No | ||
29 | GABRG2 | 2350402 4210204 6130279 6550037 | 3833 | 0.348 | -0.0253 | No | ||
30 | AFF3 | 3870102 | 4032 | 0.315 | -0.0338 | No | ||
31 | ZMYND19 | 1570706 6860551 | 4039 | 0.314 | -0.0318 | No | ||
32 | UNC5A | 2120528 3060324 | 4051 | 0.312 | -0.0301 | No | ||
33 | TBC1D4 | 6420397 | 4053 | 0.312 | -0.0279 | No | ||
34 | RNF38 | 1940746 3140133 3840601 | 4208 | 0.283 | -0.0342 | No | ||
35 | TRPS1 | 870100 | 4270 | 0.274 | -0.0355 | No | ||
36 | GAD1 | 2360035 3140167 | 4529 | 0.240 | -0.0477 | No | ||
37 | JPH1 | 610739 | 4629 | 0.230 | -0.0514 | No | ||
38 | VPS13D | 2350451 | 4684 | 0.224 | -0.0527 | No | ||
39 | CITED2 | 5670114 5130088 | 4784 | 0.213 | -0.0565 | No | ||
40 | PPP2R5C | 3310121 6650672 | 4798 | 0.212 | -0.0557 | No | ||
41 | SNAI1 | 6590253 | 4848 | 0.207 | -0.0569 | No | ||
42 | HIVEP2 | 6520538 | 4878 | 0.203 | -0.0569 | No | ||
43 | MAST1 | 6940215 | 4940 | 0.197 | -0.0588 | No | ||
44 | CDH2 | 520435 2450451 2760025 6650477 | 5313 | 0.164 | -0.0778 | No | ||
45 | SDC2 | 1980168 | 5487 | 0.151 | -0.0861 | No | ||
46 | CDH13 | 5130368 5340114 | 5514 | 0.149 | -0.0864 | No | ||
47 | TRAM2 | 3940112 | 5645 | 0.140 | -0.0925 | No | ||
48 | DLL1 | 1770377 | 5744 | 0.134 | -0.0968 | No | ||
49 | SOX21 | 1050110 4670041 6660338 | 5747 | 0.134 | -0.0960 | No | ||
50 | PDGFC | 4200133 | 5829 | 0.129 | -0.0994 | No | ||
51 | MARK1 | 450484 | 5959 | 0.121 | -0.1055 | No | ||
52 | AK5 | 6290348 | 6007 | 0.119 | -0.1072 | No | ||
53 | IL1A | 3610056 | 6048 | 0.117 | -0.1085 | No | ||
54 | NXPH1 | 3870546 | 6055 | 0.116 | -0.1080 | No | ||
55 | JUN | 840170 | 6110 | 0.114 | -0.1101 | No | ||
56 | POU4F1 | 2260315 | 6227 | 0.108 | -0.1156 | No | ||
57 | COBLL1 | 4230056 6370494 | 6400 | 0.099 | -0.1243 | No | ||
58 | HS3ST3B1 | 380040 | 6470 | 0.096 | -0.1273 | No | ||
59 | GRM5 | 60528 | 6479 | 0.096 | -0.1270 | No | ||
60 | CUL5 | 450142 | 6527 | 0.094 | -0.1289 | No | ||
61 | UBE2V2 | 4210484 | 6707 | 0.087 | -0.1380 | No | ||
62 | FZD4 | 1580520 | 6907 | 0.079 | -0.1482 | No | ||
63 | GAB1 | 2970156 | 7103 | 0.073 | -0.1583 | No | ||
64 | PTPN12 | 2030309 6020725 6130746 6290609 | 7189 | 0.071 | -0.1624 | No | ||
65 | FHOD3 | 1240541 | 7193 | 0.071 | -0.1620 | No | ||
66 | MEF2C | 670025 780338 | 7314 | 0.067 | -0.1681 | No | ||
67 | ZBTB11 | 6520092 | 7317 | 0.067 | -0.1677 | No | ||
68 | CAPN3 | 1980451 6940047 | 7325 | 0.067 | -0.1676 | No | ||
69 | CDH11 | 1230133 2100180 4610110 | 7613 | 0.059 | -0.1828 | No | ||
70 | TMEFF1 | 2680100 | 7762 | 0.055 | -0.1904 | No | ||
71 | SV2B | 3850717 | 7803 | 0.054 | -0.1922 | No | ||
72 | ENAH | 1690292 5700300 | 7869 | 0.052 | -0.1953 | No | ||
73 | IRX3 | 4200112 | 7959 | 0.050 | -0.1998 | No | ||
74 | BASP1 | 5700044 | 8210 | 0.045 | -0.2131 | No | ||
75 | LRRTM3 | 4210021 | 8308 | 0.042 | -0.2180 | No | ||
76 | NRXN3 | 1400546 3360471 | 8373 | 0.041 | -0.2212 | No | ||
77 | SRPX | 580717 1980162 | 8396 | 0.040 | -0.2221 | No | ||
78 | TTN | 2320161 4670056 6550026 | 8471 | 0.039 | -0.2258 | No | ||
79 | PSD2 | 2060091 | 8496 | 0.038 | -0.2269 | No | ||
80 | BCOR | 1660452 3940053 | 8562 | 0.037 | -0.2301 | No | ||
81 | FIGN | 7000601 | 8589 | 0.037 | -0.2313 | No | ||
82 | WDFY3 | 3610041 4560333 4570273 | 8643 | 0.036 | -0.2339 | No | ||
83 | EPHA7 | 1190288 4010278 | 8903 | 0.030 | -0.2477 | No | ||
84 | CSNK1A1 | 2340427 | 8940 | 0.030 | -0.2495 | No | ||
85 | CRSP6 | 2940358 | 8953 | 0.029 | -0.2499 | No | ||
86 | DKK2 | 3610433 | 9016 | 0.028 | -0.2531 | No | ||
87 | CPNE8 | 7040039 | 9151 | 0.026 | -0.2602 | No | ||
88 | RIMS3 | 3890563 | 9228 | 0.025 | -0.2641 | No | ||
89 | EYA1 | 1450278 5220390 | 9389 | 0.022 | -0.2727 | No | ||
90 | PIK3R1 | 4730671 | 9411 | 0.022 | -0.2736 | No | ||
91 | SNX9 | 3290592 | 9590 | 0.019 | -0.2832 | No | ||
92 | SERTAD2 | 2810673 6840450 | 9604 | 0.019 | -0.2838 | No | ||
93 | PDZRN3 | 2340131 | 9658 | 0.018 | -0.2865 | No | ||
94 | ESRRG | 4010181 | 9926 | 0.013 | -0.3009 | No | ||
95 | ARHGAP5 | 2510619 3360035 | 9961 | 0.013 | -0.3027 | No | ||
96 | BHLHB3 | 3450438 | 9991 | 0.012 | -0.3042 | No | ||
97 | ZIC1 | 670113 | 10035 | 0.011 | -0.3064 | No | ||
98 | SP4 | 3850176 | 10063 | 0.011 | -0.3078 | No | ||
99 | ADAM10 | 3780156 | 10220 | 0.008 | -0.3162 | No | ||
100 | RPE | 940114 | 10320 | 0.006 | -0.3216 | No | ||
101 | NDST1 | 1500427 5340121 | 10735 | -0.000 | -0.3441 | No | ||
102 | SP3 | 3840338 | 10973 | -0.004 | -0.3569 | No | ||
103 | SS18 | 1940440 2900072 6900129 | 11119 | -0.007 | -0.3648 | No | ||
104 | PCDH18 | 430010 | 11198 | -0.008 | -0.3689 | No | ||
105 | KCNMA1 | 1450402 | 11220 | -0.008 | -0.3700 | No | ||
106 | DACH1 | 2450593 5700592 | 11221 | -0.008 | -0.3700 | No | ||
107 | NLGN3 | 2650463 | 11241 | -0.009 | -0.3709 | No | ||
108 | NLGN1 | 5670278 | 11291 | -0.009 | -0.3735 | No | ||
109 | BHLHB5 | 6510520 | 11357 | -0.010 | -0.3770 | No | ||
110 | UNC50 | 4920037 | 11548 | -0.014 | -0.3872 | No | ||
111 | PUM2 | 4200441 5910446 | 11603 | -0.015 | -0.3900 | No | ||
112 | SALL1 | 5420020 7050195 | 11661 | -0.016 | -0.3930 | No | ||
113 | GABRA1 | 130372 | 11912 | -0.021 | -0.4065 | No | ||
114 | ZIC2 | 1410408 | 11949 | -0.021 | -0.4083 | No | ||
115 | KCNIP4 | 4120435 7050605 | 11957 | -0.022 | -0.4085 | No | ||
116 | GABRA5 | 5570215 | 12037 | -0.023 | -0.4126 | No | ||
117 | THRAP1 | 2470121 | 12182 | -0.027 | -0.4202 | No | ||
118 | TNFSF11 | 6350204 | 12548 | -0.035 | -0.4398 | No | ||
119 | GPC4 | 5910408 | 12562 | -0.035 | -0.4403 | No | ||
120 | OSBPL6 | 3800072 | 12576 | -0.036 | -0.4407 | No | ||
121 | SPEN | 2060041 | 12625 | -0.037 | -0.4430 | No | ||
122 | DUSP16 | 2370082 2480450 | 13192 | -0.055 | -0.4734 | No | ||
123 | PFN2 | 730040 5700026 | 13325 | -0.060 | -0.4801 | No | ||
124 | SEMA4C | 1980315 | 13405 | -0.063 | -0.4840 | No | ||
125 | HIPK1 | 110193 | 13682 | -0.076 | -0.4984 | No | ||
126 | WNT5A | 840685 3120152 | 13787 | -0.081 | -0.5035 | No | ||
127 | PIP5K3 | 5360112 | 13791 | -0.082 | -0.5030 | No | ||
128 | PBX3 | 1300424 3710577 6180575 | 13879 | -0.086 | -0.5071 | No | ||
129 | RSBN1 | 7000487 | 13951 | -0.091 | -0.5103 | No | ||
130 | KIF1B | 1240494 2370139 4570270 6510102 | 13965 | -0.092 | -0.5104 | No | ||
131 | SORCS3 | 5700309 | 13992 | -0.094 | -0.5111 | No | ||
132 | TJP1 | 6350184 | 14107 | -0.101 | -0.5165 | No | ||
133 | PCGF2 | 6370347 | 14171 | -0.106 | -0.5192 | No | ||
134 | SPRED2 | 510138 540195 | 14226 | -0.111 | -0.5213 | No | ||
135 | CCNT2 | 2100390 4150563 | 14235 | -0.111 | -0.5209 | No | ||
136 | E2F6 | 3120133 3850332 4070324 | 14349 | -0.122 | -0.5262 | No | ||
137 | NAB1 | 430739 1230114 3390736 6660056 | 14456 | -0.130 | -0.5310 | No | ||
138 | THRAP2 | 4920600 | 14483 | -0.134 | -0.5314 | No | ||
139 | SSH2 | 360056 | 14577 | -0.142 | -0.5354 | No | ||
140 | EIF2C1 | 6900551 | 14773 | -0.168 | -0.5448 | No | ||
141 | JARID1B | 4730494 | 14801 | -0.172 | -0.5450 | No | ||
142 | RBM12 | 4570239 6040411 6660129 | 14852 | -0.179 | -0.5464 | No | ||
143 | TLE4 | 1450064 1500519 | 14863 | -0.181 | -0.5457 | No | ||
144 | HEMGN | 670411 | 14996 | -0.202 | -0.5513 | No | ||
145 | CLASP1 | 6860279 | 15087 | -0.218 | -0.5546 | No | ||
146 | RALGPS1 | 3440129 6400746 | 15121 | -0.226 | -0.5548 | No | ||
147 | BAZ2A | 730184 | 15123 | -0.226 | -0.5532 | No | ||
148 | FBS1 | 2570520 | 15153 | -0.231 | -0.5531 | No | ||
149 | CARM1 | 7040292 | 15188 | -0.239 | -0.5532 | No | ||
150 | SPIRE2 | 450088 | 15242 | -0.251 | -0.5542 | No | ||
151 | SH2D3C | 3060014 | 15411 | -0.286 | -0.5612 | No | ||
152 | GTF2IRD1 | 2030154 3990040 5080372 | 15416 | -0.287 | -0.5594 | No | ||
153 | AXIN1 | 3360358 6940451 | 15468 | -0.299 | -0.5599 | No | ||
154 | PHF12 | 870400 3130687 | 15491 | -0.306 | -0.5589 | No | ||
155 | RPS6KA5 | 2120563 7040546 | 15553 | -0.322 | -0.5599 | No | ||
156 | AR | 6380167 | 15557 | -0.323 | -0.5576 | No | ||
157 | ANKRD17 | 2120402 3850035 6400044 | 15814 | -0.408 | -0.5686 | No | ||
158 | PDE4D | 2470528 6660014 | 15917 | -0.441 | -0.5709 | No | ||
159 | GNB1 | 2120397 | 15975 | -0.459 | -0.5706 | No | ||
160 | UBE3A | 1240152 2690438 5860609 | 15982 | -0.461 | -0.5676 | No | ||
161 | MAPK1 | 3190193 6200253 | 16096 | -0.498 | -0.5701 | No | ||
162 | FOXO1A | 3120670 | 16243 | -0.553 | -0.5740 | Yes | ||
163 | DAB2IP | 3170064 6200441 | 16249 | -0.555 | -0.5702 | Yes | ||
164 | XPO7 | 2630215 6760014 | 16261 | -0.560 | -0.5667 | Yes | ||
165 | SVIL | 2450347 4050735 4070576 4120706 5390161 5860142 6520278 7100397 | 16281 | -0.569 | -0.5635 | Yes | ||
166 | CUGBP2 | 6180121 6840139 | 16339 | -0.592 | -0.5623 | Yes | ||
167 | ARFGEF1 | 6760494 | 16345 | -0.593 | -0.5582 | Yes | ||
168 | MADD | 6100725 7000088 | 16454 | -0.638 | -0.5594 | Yes | ||
169 | RBBP6 | 2320129 | 16474 | -0.650 | -0.5557 | Yes | ||
170 | FBXO33 | 1510504 | 16499 | -0.664 | -0.5521 | Yes | ||
171 | PPP1R10 | 110136 3170725 3610484 | 16503 | -0.666 | -0.5474 | Yes | ||
172 | MLLT10 | 1410288 3290142 | 16630 | -0.735 | -0.5489 | Yes | ||
173 | ITGB1 | 5080156 6270528 | 16739 | -0.801 | -0.5489 | Yes | ||
174 | UTX | 2900017 6770452 | 16759 | -0.810 | -0.5440 | Yes | ||
175 | NUDT4 | 6760689 | 16841 | -0.860 | -0.5421 | Yes | ||
176 | RYBP | 60746 | 16895 | -0.894 | -0.5384 | Yes | ||
177 | SIPA1L2 | 4850731 | 16952 | -0.930 | -0.5346 | Yes | ||
178 | CDC14A | 4050132 | 16977 | -0.950 | -0.5290 | Yes | ||
179 | DCUN1D1 | 2360332 | 17007 | -0.972 | -0.5234 | Yes | ||
180 | PPP2R5D | 4010156 380408 5550112 5670162 | 17034 | -0.982 | -0.5177 | Yes | ||
181 | BTG1 | 4200735 6040131 6200133 | 17083 | -1.000 | -0.5129 | Yes | ||
182 | PDPK1 | 6650168 | 17086 | -1.001 | -0.5057 | Yes | ||
183 | EFTUD1 | 5360736 | 17191 | -1.054 | -0.5037 | Yes | ||
184 | DNAJC13 | 4730091 | 17225 | -1.082 | -0.4975 | Yes | ||
185 | CREBBP | 5690035 7040050 | 17238 | -1.091 | -0.4902 | Yes | ||
186 | FMNL2 | 4060438 | 17286 | -1.131 | -0.4845 | Yes | ||
187 | PHF2 | 4060300 | 17353 | -1.188 | -0.4793 | Yes | ||
188 | TTC7B | 4760725 | 17358 | -1.193 | -0.4708 | Yes | ||
189 | CDC73 | 1580132 | 17389 | -1.222 | -0.4635 | Yes | ||
190 | KBTBD2 | 2320014 | 17441 | -1.261 | -0.4570 | Yes | ||
191 | BCL7A | 4560095 | 17468 | -1.282 | -0.4491 | Yes | ||
192 | EIF4ENIF1 | 2060341 | 17486 | -1.305 | -0.4404 | Yes | ||
193 | DDX3X | 2190020 | 17667 | -1.484 | -0.4393 | Yes | ||
194 | IRF2 | 5390044 | 17728 | -1.557 | -0.4312 | Yes | ||
195 | PAIP1 | 3870576 | 17791 | -1.625 | -0.4227 | Yes | ||
196 | KLF3 | 5130438 | 17834 | -1.666 | -0.4127 | Yes | ||
197 | ITSN2 | 780484 | 17846 | -1.677 | -0.4010 | Yes | ||
198 | ZFX | 5900400 | 17912 | -1.744 | -0.3918 | Yes | ||
199 | PIAS1 | 5340301 | 18009 | -1.854 | -0.3834 | Yes | ||
200 | SRPK2 | 6380341 | 18036 | -1.872 | -0.3711 | Yes | ||
201 | DHX36 | 2470465 | 18066 | -1.905 | -0.3588 | Yes | ||
202 | NCOA1 | 3610438 | 18073 | -1.911 | -0.3451 | Yes | ||
203 | ETF1 | 6770075 | 18136 | -2.016 | -0.3337 | Yes | ||
204 | MBNL2 | 3450707 | 18177 | -2.076 | -0.3207 | Yes | ||
205 | CTDSPL | 4670546 | 18183 | -2.083 | -0.3057 | Yes | ||
206 | MTPN | 3940167 | 18216 | -2.138 | -0.2917 | Yes | ||
207 | TBK1 | 5690338 | 18268 | -2.222 | -0.2782 | Yes | ||
208 | NMT1 | 5810152 | 18336 | -2.373 | -0.2645 | Yes | ||
209 | PPP3CB | 6020156 | 18339 | -2.375 | -0.2472 | Yes | ||
210 | SFRS3 | 770315 4230593 | 18340 | -2.375 | -0.2298 | Yes | ||
211 | SIN3A | 2190121 | 18425 | -2.561 | -0.2156 | Yes | ||
212 | HMGCS1 | 6620452 | 18447 | -2.621 | -0.1976 | Yes | ||
213 | ATP2A2 | 1090075 3990279 | 18452 | -2.633 | -0.1785 | Yes | ||
214 | CLPX | 6220156 | 18462 | -2.674 | -0.1594 | Yes | ||
215 | AP3S1 | 5570044 | 18484 | -2.755 | -0.1404 | Yes | ||
216 | RHOT1 | 6760692 | 18504 | -2.826 | -0.1207 | Yes | ||
217 | APLP2 | 3610037 | 18528 | -2.931 | -0.1005 | Yes | ||
218 | ARID1A | 2630022 1690551 4810110 | 18538 | -2.995 | -0.0790 | Yes | ||
219 | UBE2G1 | 2230546 5420528 7040463 | 18555 | -3.099 | -0.0572 | Yes | ||
220 | BRD7 | 2120068 6200746 | 18604 | -3.947 | -0.0309 | Yes | ||
221 | MCL1 | 1660672 | 18610 | -4.296 | 0.0003 | Yes |