Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | VERHAAK_AML_NPM1_MUT_VS_WT_DN |
Enrichment Score (ES) | 0.5434036 |
Normalized Enrichment Score (NES) | 1.598564 |
Nominal p-value | 0.0 |
FDR q-value | 0.16509181 |
FWER p-Value | 0.966 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | SIDT1 | 7100010 | 2 | 5.462 | 0.0479 | Yes | ||
2 | GYPC | 2320102 | 20 | 4.042 | 0.0825 | Yes | ||
3 | TOX | 3440053 | 50 | 3.421 | 0.1110 | Yes | ||
4 | CST7 | 380369 | 115 | 2.985 | 0.1338 | Yes | ||
5 | ZAP70 | 1410494 2260504 | 121 | 2.950 | 0.1595 | Yes | ||
6 | TGFBI | 2060446 6900112 | 191 | 2.742 | 0.1798 | Yes | ||
7 | EVL | 1740113 | 201 | 2.713 | 0.2032 | Yes | ||
8 | CD200 | 940725 5260647 | 347 | 2.371 | 0.2162 | Yes | ||
9 | LHFPL2 | 450020 | 371 | 2.327 | 0.2354 | Yes | ||
10 | ATP9A | 4780673 5390280 | 385 | 2.297 | 0.2549 | Yes | ||
11 | GMPR | 3990022 | 480 | 2.160 | 0.2688 | Yes | ||
12 | HIST1H2BG | 5670632 | 717 | 1.890 | 0.2726 | Yes | ||
13 | CD2 | 430672 | 723 | 1.885 | 0.2889 | Yes | ||
14 | HSPB1 | 6760435 | 750 | 1.859 | 0.3038 | Yes | ||
15 | PRODH | 1240452 | 811 | 1.804 | 0.3164 | Yes | ||
16 | SERPING1 | 5550440 | 842 | 1.761 | 0.3303 | Yes | ||
17 | RBPMS | 3990494 | 900 | 1.713 | 0.3422 | Yes | ||
18 | ASS1 | 1580632 4070082 | 954 | 1.661 | 0.3540 | Yes | ||
19 | SERPINF1 | 7040367 | 994 | 1.624 | 0.3661 | Yes | ||
20 | ALAS2 | 6550176 | 1022 | 1.598 | 0.3787 | Yes | ||
21 | ITM2C | 780647 | 1188 | 1.477 | 0.3827 | Yes | ||
22 | CHI3L1 | 1170039 | 1362 | 1.360 | 0.3853 | Yes | ||
23 | NARFL | 2260372 4050341 | 1404 | 1.337 | 0.3949 | Yes | ||
24 | TRIB2 | 4120605 | 1435 | 1.321 | 0.4048 | Yes | ||
25 | CD3D | 2810739 | 1543 | 1.243 | 0.4100 | Yes | ||
26 | LCN2 | 2510112 | 1568 | 1.231 | 0.4195 | Yes | ||
27 | SSBP2 | 2260725 2900400 4730711 | 1689 | 1.151 | 0.4231 | Yes | ||
28 | YPEL1 | 6590435 | 1690 | 1.150 | 0.4332 | Yes | ||
29 | ISG20 | 1770750 | 1724 | 1.129 | 0.4413 | Yes | ||
30 | PTPRCAP | 6650075 | 1744 | 1.116 | 0.4501 | Yes | ||
31 | CACNA2D2 | 520736 | 1777 | 1.086 | 0.4579 | Yes | ||
32 | MPO | 2360176 2760440 5690176 | 1862 | 1.045 | 0.4626 | Yes | ||
33 | PRTN3 | 6900670 | 1882 | 1.035 | 0.4706 | Yes | ||
34 | HSPG2 | 2510687 6220750 | 1889 | 1.032 | 0.4794 | Yes | ||
35 | EGFL7 | 150113 670170 3840707 | 1895 | 1.029 | 0.4882 | Yes | ||
36 | IFITM1 | 1690601 3120438 6510075 | 1915 | 1.022 | 0.4961 | Yes | ||
37 | BLNK | 70288 6590092 | 1942 | 1.009 | 0.5036 | Yes | ||
38 | IGFBP7 | 520411 3060110 5290152 | 2028 | 0.984 | 0.5076 | Yes | ||
39 | SNCA | 5340673 | 2061 | 0.967 | 0.5144 | Yes | ||
40 | FZD2 | 6480154 | 2076 | 0.962 | 0.5221 | Yes | ||
41 | DLK1 | 1240138 | 2234 | 0.888 | 0.5214 | Yes | ||
42 | BZRAP1 | 5290487 | 2422 | 0.794 | 0.5182 | Yes | ||
43 | SCRN1 | 6040025 6580019 | 2428 | 0.791 | 0.5249 | Yes | ||
44 | MSLN | 2640048 | 2748 | 0.651 | 0.5133 | Yes | ||
45 | ADIPOR1 | 3140440 | 2762 | 0.644 | 0.5183 | Yes | ||
46 | CD7 | 3140465 | 2796 | 0.633 | 0.5220 | Yes | ||
47 | PLXND1 | 5270682 | 2809 | 0.631 | 0.5269 | Yes | ||
48 | HPGD | 6770192 | 2902 | 0.599 | 0.5272 | Yes | ||
49 | SERPINE2 | 2810390 | 2924 | 0.591 | 0.5313 | Yes | ||
50 | TNFRSF21 | 6380100 | 2983 | 0.570 | 0.5331 | Yes | ||
51 | CIITA | 2650242 | 2990 | 0.568 | 0.5378 | Yes | ||
52 | TACSTD2 | 6660341 | 3098 | 0.529 | 0.5366 | Yes | ||
53 | ICAM4 | 6770053 | 3117 | 0.521 | 0.5403 | Yes | ||
54 | BAALC | 5310133 6450170 | 3143 | 0.512 | 0.5434 | Yes | ||
55 | MMP9 | 580338 | 3236 | 0.483 | 0.5427 | No | ||
56 | KIT | 7040095 | 3383 | 0.442 | 0.5386 | No | ||
57 | SORL1 | 630204 | 3684 | 0.377 | 0.5257 | No | ||
58 | FGF13 | 630575 1570440 5360121 | 3714 | 0.371 | 0.5273 | No | ||
59 | SPRY1 | 450253 460093 | 3811 | 0.351 | 0.5252 | No | ||
60 | PROM1 | 3170537 | 3946 | 0.329 | 0.5209 | No | ||
61 | TSPAN7 | 870133 | 3995 | 0.322 | 0.5211 | No | ||
62 | DEPDC6 | 730326 5820239 | 4000 | 0.321 | 0.5237 | No | ||
63 | GJA1 | 5220731 | 4162 | 0.290 | 0.5175 | No | ||
64 | TRAF5 | 3290064 | 4237 | 0.278 | 0.5159 | No | ||
65 | APP | 2510053 | 4242 | 0.278 | 0.5181 | No | ||
66 | MEF2A | 2350041 3360128 6040180 | 4341 | 0.266 | 0.5152 | No | ||
67 | B4GALT6 | 1850176 2340687 | 4510 | 0.243 | 0.5082 | No | ||
68 | MS4A3 | 2480309 2690086 | 4610 | 0.233 | 0.5049 | No | ||
69 | EVI1 | 2000193 2680494 | 4622 | 0.231 | 0.5063 | No | ||
70 | TFPI | 1400288 5550008 | 4730 | 0.218 | 0.5024 | No | ||
71 | SYNGR1 | 5130452 6650056 | 4771 | 0.214 | 0.5021 | No | ||
72 | PTPRM | 6370136 | 4840 | 0.208 | 0.5003 | No | ||
73 | CYP2E1 | 4480209 | 4888 | 0.203 | 0.4995 | No | ||
74 | VPREB1 | 3520280 | 4891 | 0.202 | 0.5012 | No | ||
75 | VLDLR | 870722 3060047 5340452 6550131 | 4943 | 0.197 | 0.5001 | No | ||
76 | RGS1 | 4060347 4540181 | 5036 | 0.188 | 0.4968 | No | ||
77 | PTGIR | 2100563 | 5155 | 0.177 | 0.4919 | No | ||
78 | TRH | 5050576 | 5208 | 0.173 | 0.4906 | No | ||
79 | SLC38A1 | 520465 | 5256 | 0.168 | 0.4896 | No | ||
80 | TGFB1I1 | 2060288 6550450 | 5331 | 0.163 | 0.4870 | No | ||
81 | FGFR1 | 2190095 4570161 | 5417 | 0.156 | 0.4838 | No | ||
82 | FHL1 | 60278 | 5630 | 0.141 | 0.4735 | No | ||
83 | PALM | 130601 3850017 | 5798 | 0.131 | 0.4656 | No | ||
84 | TSPAN13 | 1690450 | 5832 | 0.129 | 0.4649 | No | ||
85 | CLDN15 | 4150270 4730592 | 5861 | 0.127 | 0.4645 | No | ||
86 | RETN | 1050041 | 5966 | 0.121 | 0.4599 | No | ||
87 | RUNX3 | 3800546 | 5980 | 0.121 | 0.4603 | No | ||
88 | DPYSL2 | 2100427 3130112 5700324 | 6141 | 0.112 | 0.4526 | No | ||
89 | IL5RA | 4540091 | 6147 | 0.111 | 0.4533 | No | ||
90 | EHD3 | 5360484 | 6221 | 0.108 | 0.4503 | No | ||
91 | POU4F1 | 2260315 | 6227 | 0.108 | 0.4510 | No | ||
92 | LMO4 | 3800746 | 6356 | 0.101 | 0.4449 | No | ||
93 | P2RY5 | 3800136 | 6487 | 0.096 | 0.4387 | No | ||
94 | TMOD1 | 3850100 | 6497 | 0.095 | 0.4390 | No | ||
95 | CLEC5A | 6420139 | 6516 | 0.095 | 0.4389 | No | ||
96 | RHOBTB3 | 4010687 | 6654 | 0.089 | 0.4322 | No | ||
97 | TKTL1 | 2810672 6760102 | 6673 | 0.088 | 0.4320 | No | ||
98 | SPON1 | 1660301 | 7036 | 0.075 | 0.4131 | No | ||
99 | P2RX5 | 5570427 6130435 | 7143 | 0.072 | 0.4079 | No | ||
100 | MEST | 4780440 6620292 | 7211 | 0.070 | 0.4049 | No | ||
101 | IFI16 | 6520601 | 7233 | 0.069 | 0.4044 | No | ||
102 | MEF2C | 670025 780338 | 7314 | 0.067 | 0.4006 | No | ||
103 | PTRF | 2260204 | 7434 | 0.063 | 0.3947 | No | ||
104 | PPP4R2 | 5890035 | 7438 | 0.063 | 0.3951 | No | ||
105 | ADCY3 | 2350347 3440242 | 7660 | 0.058 | 0.3837 | No | ||
106 | ROBO1 | 3710398 | 7799 | 0.054 | 0.3766 | No | ||
107 | CSF3R | 670500 2640239 3440091 5690020 | 7842 | 0.053 | 0.3748 | No | ||
108 | CAV1 | 870025 | 7984 | 0.050 | 0.3676 | No | ||
109 | CD19 | 6940692 | 8125 | 0.046 | 0.3604 | No | ||
110 | ELA2 | 1570452 5270129 | 8214 | 0.045 | 0.3560 | No | ||
111 | ST18 | 5720537 | 8379 | 0.041 | 0.3475 | No | ||
112 | BANK1 | 50750 | 8598 | 0.037 | 0.3360 | No | ||
113 | GSN | 3830168 | 8622 | 0.036 | 0.3351 | No | ||
114 | PMAIP1 | 1400717 5360047 5900039 | 8767 | 0.033 | 0.3275 | No | ||
115 | EPS8 | 7050204 | 9057 | 0.028 | 0.3121 | No | ||
116 | GPM6B | 6220458 | 9126 | 0.027 | 0.3087 | No | ||
117 | TRPM4 | 6980270 | 9220 | 0.025 | 0.3038 | No | ||
118 | AGTPBP1 | 1990735 | 9303 | 0.024 | 0.2996 | No | ||
119 | PTGER4 | 6400670 | 9319 | 0.023 | 0.2990 | No | ||
120 | OPTN | 3940041 | 9570 | 0.019 | 0.2856 | No | ||
121 | NT5E | 2030603 1400731 | 9572 | 0.019 | 0.2857 | No | ||
122 | ARHGEF12 | 3990195 | 9615 | 0.018 | 0.2836 | No | ||
123 | F2RL1 | 3290279 | 9824 | 0.015 | 0.2724 | No | ||
124 | CCND2 | 5340167 | 9898 | 0.014 | 0.2686 | No | ||
125 | CD38 | 6100056 | 10326 | 0.006 | 0.2455 | No | ||
126 | GPA33 | 2650044 | 10543 | 0.003 | 0.2338 | No | ||
127 | MYH11 | 7100273 | 10648 | 0.001 | 0.2281 | No | ||
128 | GPSM2 | 2260053 | 10767 | -0.001 | 0.2218 | No | ||
129 | CD34 | 6650270 | 10872 | -0.002 | 0.2161 | No | ||
130 | STK32B | 7000204 | 10915 | -0.003 | 0.2139 | No | ||
131 | NCAM1 | 3140026 | 11005 | -0.005 | 0.2091 | No | ||
132 | MST1 | 1400403 | 11192 | -0.008 | 0.1991 | No | ||
133 | DACH1 | 2450593 5700592 | 11221 | -0.008 | 0.1976 | No | ||
134 | PAM | 5290528 | 11865 | -0.020 | 0.1629 | No | ||
135 | NBL1 | 2480021 | 11890 | -0.020 | 0.1618 | No | ||
136 | PDE3B | 2030563 | 11926 | -0.021 | 0.1601 | No | ||
137 | FCER1A | 1050671 | 11929 | -0.021 | 0.1601 | No | ||
138 | NPR3 | 1580239 | 11950 | -0.021 | 0.1593 | No | ||
139 | DCHS1 | 4850487 | 11960 | -0.022 | 0.1590 | No | ||
140 | BPGM | 5080520 | 12049 | -0.024 | 0.1544 | No | ||
141 | FZD6 | 360288 | 12217 | -0.027 | 0.1456 | No | ||
142 | GNAI1 | 4560390 | 12262 | -0.028 | 0.1434 | No | ||
143 | DHRS3 | 360609 | 12448 | -0.033 | 0.1337 | No | ||
144 | GNG7 | 1940019 | 12486 | -0.033 | 0.1320 | No | ||
145 | PDE4B | 4480121 | 12688 | -0.039 | 0.1214 | No | ||
146 | CD48 | 1570647 | 12914 | -0.045 | 0.1096 | No | ||
147 | PRKD3 | 5220520 5890519 | 13346 | -0.061 | 0.0867 | No | ||
148 | MPL | 2360253 | 13483 | -0.067 | 0.0800 | No | ||
149 | TM6SF1 | 730181 | 13529 | -0.069 | 0.0781 | No | ||
150 | HGF | 3360593 | 13659 | -0.075 | 0.0718 | No | ||
151 | GALC | 2260685 4810161 6370040 | 13716 | -0.077 | 0.0694 | No | ||
152 | KCNE1L | 4670092 | 13760 | -0.080 | 0.0678 | No | ||
153 | SPARC | 1690086 | 13851 | -0.085 | 0.0637 | No | ||
154 | ITGA6 | 3830129 | 14095 | -0.100 | 0.0514 | No | ||
155 | GATM | 380671 | 14245 | -0.112 | 0.0443 | No | ||
156 | SH3BP4 | 3140242 | 14461 | -0.131 | 0.0337 | No | ||
157 | MLLT3 | 510204 3850722 6200088 | 14519 | -0.136 | 0.0319 | No | ||
158 | CCR2 | 1450519 | 14557 | -0.140 | 0.0311 | No | ||
159 | TCF3 | 5080022 | 14799 | -0.172 | 0.0195 | No | ||
160 | ARHGEF17 | 2060008 | 14984 | -0.200 | 0.0113 | No | ||
161 | ERG | 50154 1770739 | 15307 | -0.264 | -0.0039 | No | ||
162 | LAMC1 | 4730025 | 15310 | -0.264 | -0.0017 | No | ||
163 | CD69 | 380167 4730088 | 15481 | -0.303 | -0.0082 | No | ||
164 | NEDD4 | 460736 1190280 | 15607 | -0.339 | -0.0120 | No | ||
165 | CENTD1 | 2570592 | 15660 | -0.354 | -0.0117 | No | ||
166 | AK3L1 | 7100601 | 15694 | -0.367 | -0.0103 | No | ||
167 | JUP | 2510671 | 15925 | -0.443 | -0.0189 | No | ||
168 | ALDH2 | 4230019 | 15977 | -0.460 | -0.0176 | No | ||
169 | ZHX2 | 2900452 | 15981 | -0.461 | -0.0137 | No | ||
170 | ABLIM1 | 580170 3710338 6520504 | 15997 | -0.466 | -0.0104 | No | ||
171 | RAMP1 | 2320168 | 16004 | -0.467 | -0.0066 | No | ||
172 | MX1 | 2690301 6840364 | 16182 | -0.531 | -0.0116 | No | ||
173 | FOXO1A | 3120670 | 16243 | -0.553 | -0.0100 | No | ||
174 | RPS6KA2 | 2970161 4730278 | 16612 | -0.726 | -0.0236 | No | ||
175 | GATA3 | 6130068 | 16831 | -0.855 | -0.0279 | No | ||
176 | RRAGD | 670075 | 16869 | -0.879 | -0.0221 | No | ||
177 | WASF1 | 2060484 | 16941 | -0.925 | -0.0179 | No | ||
178 | DNTT | 670162 | 17011 | -0.974 | -0.0131 | No | ||
179 | PPP1R16B | 3520300 | 17237 | -1.091 | -0.0157 | No | ||
180 | FLNB | 2510575 | 17311 | -1.148 | -0.0095 | No | ||
181 | H1F0 | 1400408 | 17357 | -1.192 | -0.0015 | No | ||
182 | UGCG | 3420053 | 17386 | -1.219 | 0.0077 | No | ||
183 | EMP1 | 4120438 | 17427 | -1.248 | 0.0165 | No | ||
184 | ITM2A | 460576 4210086 | 17474 | -1.289 | 0.0253 | No | ||
185 | VIL2 | 5570161 | 17922 | -1.755 | 0.0165 | No | ||
186 | POLE | 6020538 | 18351 | -2.398 | 0.0144 | No |