Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
| Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
| Upregulated in class | wtNotch |
| GeneSet | REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS |
| Enrichment Score (ES) | -0.6774672 |
| Normalized Enrichment Score (NES) | -1.6143832 |
| Nominal p-value | 0.004651163 |
| FDR q-value | 0.20208539 |
| FWER p-Value | 0.921 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | RFC5 | 3800452 6020091 | 1531 | 1.251 | -0.0188 | No | ||
| 2 | MCM2 | 5050139 | 3319 | 0.459 | -0.0916 | No | ||
| 3 | MCM5 | 2680647 | 3531 | 0.411 | -0.0820 | No | ||
| 4 | MCM3 | 5570068 | 5213 | 0.172 | -0.1637 | No | ||
| 5 | RAD1 | 4200551 | 5893 | 0.125 | -0.1939 | No | ||
| 6 | RFC3 | 1980600 | 7145 | 0.072 | -0.2575 | No | ||
| 7 | CHEK1 | 50167 1940300 | 13289 | -0.059 | -0.5849 | No | ||
| 8 | MCM10 | 4920632 | 13362 | -0.062 | -0.5857 | No | ||
| 9 | CDC25C | 2570673 4760161 6520707 | 14375 | -0.124 | -0.6338 | No | ||
| 10 | ORC2L | 1990470 6510019 | 14587 | -0.144 | -0.6378 | No | ||
| 11 | ORC1L | 2370328 6110390 | 15143 | -0.230 | -0.6560 | Yes | ||
| 12 | RPA2 | 2760301 5420195 | 15395 | -0.283 | -0.6551 | Yes | ||
| 13 | CDK2 | 130484 2260301 4010088 5050110 | 15400 | -0.284 | -0.6409 | Yes | ||
| 14 | ORC4L | 4230538 5550288 | 16081 | -0.494 | -0.6523 | Yes | ||
| 15 | HUS1 | 3440494 3800156 | 16187 | -0.533 | -0.6309 | Yes | ||
| 16 | MCM7 | 3290292 5220056 | 16282 | -0.569 | -0.6071 | Yes | ||
| 17 | CDC25A | 3800184 | 16404 | -0.617 | -0.5822 | Yes | ||
| 18 | CDC45L | 70537 3130114 | 16566 | -0.690 | -0.5558 | Yes | ||
| 19 | RAD9B | 2320064 | 16609 | -0.722 | -0.5213 | Yes | ||
| 20 | MCM6 | 60092 540181 6510110 | 16794 | -0.831 | -0.4890 | Yes | ||
| 21 | ORC5L | 1940133 1940711 | 17603 | -1.414 | -0.4606 | Yes | ||
| 22 | MCM4 | 2760673 5420711 | 17712 | -1.538 | -0.3882 | Yes | ||
| 23 | RPA3 | 5700136 | 17795 | -1.631 | -0.3097 | Yes | ||
| 24 | CDC7 | 4060546 4850041 | 17891 | -1.718 | -0.2275 | Yes | ||
| 25 | RPA1 | 360452 | 18231 | -2.159 | -0.1360 | Yes | ||
| 26 | RFC4 | 3800082 6840142 | 18552 | -3.081 | 0.0034 | Yes |
