Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
| Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | SH3_SH2_ADAPTOR_ACTIVITY |
| Enrichment Score (ES) | -0.6870611 |
| Normalized Enrichment Score (NES) | -1.6197724 |
| Nominal p-value | 0.007853403 |
| FDR q-value | 0.51794165 |
| FWER p-Value | 0.852 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | GRB2 | 6650398 | 1856 | 1.865 | -0.0587 | No | ||
| 2 | SH3BGRL | 2060110 | 2448 | 1.259 | -0.0627 | No | ||
| 3 | RUSC1 | 6450093 6980575 | 2778 | 1.008 | -0.0582 | No | ||
| 4 | BLNK | 70288 6590092 | 2842 | 0.985 | -0.0398 | No | ||
| 5 | GRB7 | 2100471 | 3736 | 0.513 | -0.0766 | No | ||
| 6 | ARHGAP1 | 2810010 5270064 | 3803 | 0.490 | -0.0693 | No | ||
| 7 | SHB | 4920494 | 3849 | 0.476 | -0.0612 | No | ||
| 8 | GRAP2 | 7100441 1410647 | 3859 | 0.474 | -0.0512 | No | ||
| 9 | CHN2 | 870528 | 4787 | 0.267 | -0.0952 | No | ||
| 10 | CNTNAP1 | 6650132 | 5399 | 0.193 | -0.1239 | No | ||
| 11 | SH3BP2 | 610131 | 5676 | 0.166 | -0.1351 | No | ||
| 12 | GRB14 | 510035 3060369 | 6249 | 0.120 | -0.1632 | No | ||
| 13 | IRS4 | 430341 1190450 | 7184 | 0.078 | -0.2117 | No | ||
| 14 | SH2D3C | 3060014 | 7196 | 0.077 | -0.2106 | No | ||
| 15 | ARHGAP6 | 2060121 | 7647 | 0.064 | -0.2334 | No | ||
| 16 | EPS8 | 7050204 | 7994 | 0.054 | -0.2509 | No | ||
| 17 | SKAP2 | 6760500 | 9165 | 0.029 | -0.3132 | No | ||
| 18 | ABI2 | 940368 4200092 | 11549 | -0.011 | -0.4412 | No | ||
| 19 | GRB10 | 6980082 | 12870 | -0.043 | -0.5113 | No | ||
| 20 | SRC | 580132 | 13241 | -0.057 | -0.5299 | No | ||
| 21 | GRAP | 1770195 | 13272 | -0.059 | -0.5303 | No | ||
| 22 | CHN1 | 6040441 | 13279 | -0.059 | -0.5293 | No | ||
| 23 | SH3BGR | 840400 | 13462 | -0.069 | -0.5376 | No | ||
| 24 | SNX9 | 3290592 | 14242 | -0.134 | -0.5765 | No | ||
| 25 | STAM | 3850008 4760441 | 14960 | -0.301 | -0.6085 | No | ||
| 26 | LASP1 | 1690528 2190341 6420341 | 15493 | -0.525 | -0.6255 | No | ||
| 27 | VAV3 | 1050731 2450242 2680653 | 15709 | -0.646 | -0.6228 | No | ||
| 28 | LAT | 3170025 | 16561 | -1.244 | -0.6412 | Yes | ||
| 29 | KHDRBS1 | 1240403 6040040 | 17415 | -2.292 | -0.6365 | Yes | ||
| 30 | ITSN2 | 780484 | 17688 | -2.790 | -0.5895 | Yes | ||
| 31 | SLA | 2000070 | 17755 | -2.940 | -0.5281 | Yes | ||
| 32 | SH2D2A | 2970594 | 17865 | -3.186 | -0.4636 | Yes | ||
| 33 | GAB1 | 2970156 | 17889 | -3.238 | -0.3934 | Yes | ||
| 34 | SOCS2 | 4760692 | 17895 | -3.247 | -0.3220 | Yes | ||
| 35 | TOB1 | 4150138 | 18291 | -4.690 | -0.2397 | Yes | ||
| 36 | CRKL | 4050427 | 18419 | -5.557 | -0.1238 | Yes | ||
| 37 | ARHGAP4 | 1940022 | 18482 | -6.085 | 0.0072 | Yes |
