Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
Upregulated in class | truncNotch |
GeneSet | V$USF_C |
Enrichment Score (ES) | 0.46562725 |
Normalized Enrichment Score (NES) | 1.2634202 |
Nominal p-value | 0.03628447 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | G6PC3 | 1580487 5390253 | 24 | 9.367 | 0.0350 | Yes | ||
2 | ABCB6 | 6350138 | 55 | 8.001 | 0.0644 | Yes | ||
3 | FBL | 5130020 | 63 | 7.719 | 0.0940 | Yes | ||
4 | RPS19 | 5860066 | 151 | 6.362 | 0.1140 | Yes | ||
5 | PFDN2 | 4230156 | 196 | 5.888 | 0.1344 | Yes | ||
6 | IPO4 | 5050619 | 199 | 5.881 | 0.1571 | Yes | ||
7 | EXOSC5 | 3370671 | 258 | 5.520 | 0.1754 | Yes | ||
8 | PA2G4 | 2030463 | 277 | 5.334 | 0.1951 | Yes | ||
9 | EXOSC2 | 6900471 | 345 | 4.933 | 0.2106 | Yes | ||
10 | NUDC | 4780025 | 376 | 4.782 | 0.2275 | Yes | ||
11 | ENO3 | 5270136 | 448 | 4.550 | 0.2413 | Yes | ||
12 | HMOX1 | 1740687 | 484 | 4.425 | 0.2566 | Yes | ||
13 | PSEN2 | 130382 | 575 | 4.117 | 0.2677 | Yes | ||
14 | PPAT | 1980019 | 630 | 3.927 | 0.2800 | Yes | ||
15 | HSPE1 | 3170438 | 670 | 3.793 | 0.2926 | Yes | ||
16 | TIMM10 | 610070 1450019 | 680 | 3.769 | 0.3067 | Yes | ||
17 | SDC1 | 3440471 6350408 | 768 | 3.555 | 0.3158 | Yes | ||
18 | ANXA6 | 2190014 | 882 | 3.265 | 0.3223 | Yes | ||
19 | OPRS1 | 6130128 6290717 | 884 | 3.260 | 0.3349 | Yes | ||
20 | HERPUD1 | 7100440 | 918 | 3.196 | 0.3455 | Yes | ||
21 | EIF4B | 5390563 5270577 | 1080 | 2.905 | 0.3481 | Yes | ||
22 | HYAL2 | 1500152 | 1219 | 2.671 | 0.3509 | Yes | ||
23 | PSMB3 | 4280594 | 1223 | 2.661 | 0.3611 | Yes | ||
24 | RHEBL1 | 2810576 | 1310 | 2.521 | 0.3662 | Yes | ||
25 | SLC39A7 | 5570131 | 1336 | 2.489 | 0.3745 | Yes | ||
26 | SH3KBP1 | 670102 2850458 7000309 | 1392 | 2.405 | 0.3808 | Yes | ||
27 | PER1 | 3290315 | 1425 | 2.364 | 0.3883 | Yes | ||
28 | POLR2H | 5890242 | 1455 | 2.332 | 0.3958 | Yes | ||
29 | GPD1 | 2480095 | 1502 | 2.277 | 0.4021 | Yes | ||
30 | LYAR | 7000402 | 1568 | 2.177 | 0.4070 | Yes | ||
31 | BCKDHA | 50189 | 1670 | 2.054 | 0.4095 | Yes | ||
32 | MYST3 | 5270500 | 1680 | 2.048 | 0.4170 | Yes | ||
33 | HMGN2 | 3140091 | 1787 | 1.946 | 0.4187 | Yes | ||
34 | PABPC4 | 1990170 6760270 5390138 | 1804 | 1.930 | 0.4254 | Yes | ||
35 | EIF2C2 | 770451 | 1822 | 1.913 | 0.4319 | Yes | ||
36 | ALDH3B1 | 4210010 6940403 | 1830 | 1.904 | 0.4389 | Yes | ||
37 | FKBP11 | 3170575 | 1950 | 1.765 | 0.4393 | Yes | ||
38 | RPL22 | 4070070 | 1952 | 1.764 | 0.4461 | Yes | ||
39 | BHLHB2 | 7040603 | 1959 | 1.760 | 0.4526 | Yes | ||
40 | POLR3E | 380152 | 2025 | 1.692 | 0.4556 | Yes | ||
41 | AKAP12 | 1450739 | 2060 | 1.646 | 0.4601 | Yes | ||
42 | PABPC1 | 2650180 2690253 6020632 1990270 | 2199 | 1.494 | 0.4584 | Yes | ||
43 | IPO13 | 3870088 | 2301 | 1.411 | 0.4584 | Yes | ||
44 | SRP72 | 3990427 | 2307 | 1.408 | 0.4636 | Yes | ||
45 | PAICS | 610142 | 2378 | 1.343 | 0.4650 | Yes | ||
46 | FARP1 | 5290102 7100341 | 2513 | 1.192 | 0.4624 | Yes | ||
47 | AMPD2 | 630093 1170070 | 2538 | 1.171 | 0.4656 | Yes | ||
48 | FHOD1 | 2680279 | 2670 | 1.072 | 0.4627 | No | ||
49 | RUSC1 | 6450093 6980575 | 2778 | 1.008 | 0.4608 | No | ||
50 | BCL9L | 6940053 | 2991 | 0.892 | 0.4527 | No | ||
51 | GRK6 | 1500053 | 2999 | 0.884 | 0.4558 | No | ||
52 | TNFRSF21 | 6380100 | 3000 | 0.883 | 0.4592 | No | ||
53 | ARF6 | 3520026 | 3174 | 0.768 | 0.4528 | No | ||
54 | CACNA1D | 1740315 4730731 | 3181 | 0.766 | 0.4555 | No | ||
55 | UBE1 | 4150139 7050463 | 3393 | 0.649 | 0.4465 | No | ||
56 | MYOHD1 | 1410520 | 3556 | 0.581 | 0.4400 | No | ||
57 | CNNM1 | 2190433 | 3575 | 0.570 | 0.4412 | No | ||
58 | LTBR | 2450341 | 3582 | 0.566 | 0.4431 | No | ||
59 | MPP3 | 1400056 4480411 6770168 | 3842 | 0.478 | 0.4309 | No | ||
60 | NR1D1 | 2360471 770746 6590204 | 3902 | 0.461 | 0.4295 | No | ||
61 | SYT3 | 6380017 | 4018 | 0.428 | 0.4249 | No | ||
62 | SUCLG2 | 5340397 5700270 | 4053 | 0.419 | 0.4247 | No | ||
63 | GTF2H1 | 2570746 2650148 | 4099 | 0.405 | 0.4238 | No | ||
64 | UBXD3 | 5050193 | 4163 | 0.390 | 0.4219 | No | ||
65 | AVP | 2100113 | 4168 | 0.388 | 0.4232 | No | ||
66 | SOCS5 | 3830398 7100093 | 4178 | 0.386 | 0.4242 | No | ||
67 | TIMM9 | 2450484 | 4219 | 0.376 | 0.4235 | No | ||
68 | ETV4 | 2450605 | 4317 | 0.349 | 0.4196 | No | ||
69 | B4GALT2 | 780037 | 4344 | 0.344 | 0.4195 | No | ||
70 | CTSF | 6100021 | 4493 | 0.318 | 0.4127 | No | ||
71 | MNT | 4920575 | 4645 | 0.292 | 0.4057 | No | ||
72 | RUNX2 | 1400193 4230215 | 4901 | 0.250 | 0.3928 | No | ||
73 | HOXA3 | 3610632 6020358 | 4903 | 0.250 | 0.3937 | No | ||
74 | HPCAL4 | 2600484 | 5319 | 0.201 | 0.3720 | No | ||
75 | TBX4 | 3060008 | 5372 | 0.195 | 0.3699 | No | ||
76 | TIAL1 | 4150048 6510605 | 5411 | 0.191 | 0.3686 | No | ||
77 | SLC26A2 | 2360278 | 5452 | 0.186 | 0.3671 | No | ||
78 | DNMT3A | 4050068 4810717 | 5469 | 0.184 | 0.3670 | No | ||
79 | NXPH1 | 3870546 | 5494 | 0.181 | 0.3664 | No | ||
80 | BMP2K | 60541 5570504 | 5709 | 0.162 | 0.3554 | No | ||
81 | ETV1 | 70735 2940603 5080463 | 6155 | 0.127 | 0.3317 | No | ||
82 | DNAJB9 | 460114 | 6522 | 0.107 | 0.3123 | No | ||
83 | RPL13A | 2680519 5700142 | 6606 | 0.103 | 0.3082 | No | ||
84 | GRIN2A | 6550538 | 6647 | 0.101 | 0.3064 | No | ||
85 | SLC6A15 | 5290176 6040017 | 6835 | 0.093 | 0.2966 | No | ||
86 | CGN | 5890139 6370167 6400537 | 7054 | 0.083 | 0.2851 | No | ||
87 | NLN | 1450576 5870575 | 7070 | 0.083 | 0.2846 | No | ||
88 | LAP3 | 2570064 | 7125 | 0.081 | 0.2820 | No | ||
89 | HS3ST3A1 | 2230497 | 7314 | 0.074 | 0.2721 | No | ||
90 | ARRDC3 | 4610390 | 7538 | 0.066 | 0.2603 | No | ||
91 | ADAMTS17 | 6510739 | 7746 | 0.061 | 0.2493 | No | ||
92 | TLL1 | 2680315 | 8094 | 0.052 | 0.2306 | No | ||
93 | STMN1 | 1990717 | 8289 | 0.047 | 0.2203 | No | ||
94 | POGK | 5290315 | 8408 | 0.045 | 0.2141 | No | ||
95 | DRD1 | 430025 | 8409 | 0.045 | 0.2142 | No | ||
96 | FADS3 | 3120079 | 8679 | 0.039 | 0.1998 | No | ||
97 | NKX2-3 | 1990736 6940088 | 8780 | 0.037 | 0.1945 | No | ||
98 | COL2A1 | 460446 3940500 | 8808 | 0.036 | 0.1932 | No | ||
99 | CHST11 | 6760546 | 8998 | 0.032 | 0.1831 | No | ||
100 | SC5DL | 6650390 | 9085 | 0.031 | 0.1785 | No | ||
101 | SLC12A5 | 1980692 | 9505 | 0.024 | 0.1559 | No | ||
102 | HPCA | 6860010 | 9522 | 0.023 | 0.1551 | No | ||
103 | MTHFD1 | 5900398 6520427 | 9708 | 0.020 | 0.1451 | No | ||
104 | SYT6 | 2510280 3850128 4540064 | 9729 | 0.020 | 0.1441 | No | ||
105 | FLT3 | 2640487 | 9848 | 0.018 | 0.1378 | No | ||
106 | PAX6 | 1190025 | 9897 | 0.017 | 0.1352 | No | ||
107 | GPRC5C | 1580372 | 9901 | 0.017 | 0.1352 | No | ||
108 | BMP4 | 380113 | 9938 | 0.016 | 0.1333 | No | ||
109 | KIAA0427 | 1690435 | 10029 | 0.015 | 0.1284 | No | ||
110 | ABCA1 | 6290156 | 10073 | 0.014 | 0.1262 | No | ||
111 | ARX | 6900504 | 10217 | 0.012 | 0.1184 | No | ||
112 | CHRM1 | 4280619 | 10310 | 0.010 | 0.1135 | No | ||
113 | PRKCE | 5700053 | 10501 | 0.007 | 0.1032 | No | ||
114 | HOXC12 | 5270411 | 10558 | 0.006 | 0.1002 | No | ||
115 | FGF11 | 840292 | 10593 | 0.006 | 0.0984 | No | ||
116 | LIN28 | 6590672 | 10871 | 0.001 | 0.0834 | No | ||
117 | SATB2 | 2470181 | 10987 | -0.001 | 0.0771 | No | ||
118 | SGTB | 460170 | 11308 | -0.006 | 0.0598 | No | ||
119 | EIF3S1 | 6130368 6770044 | 11332 | -0.007 | 0.0586 | No | ||
120 | FGF14 | 2630390 3520075 6770048 | 11418 | -0.009 | 0.0540 | No | ||
121 | HOXC13 | 4070722 | 11553 | -0.011 | 0.0468 | No | ||
122 | NPTX1 | 3710736 | 11852 | -0.017 | 0.0307 | No | ||
123 | NPM1 | 4730427 | 12091 | -0.022 | 0.0178 | No | ||
124 | LHX9 | 2350112 | 12245 | -0.026 | 0.0096 | No | ||
125 | PLA2G4A | 6380364 | 12255 | -0.026 | 0.0092 | No | ||
126 | HHIP | 6940438 | 12397 | -0.030 | 0.0017 | No | ||
127 | PIGW | 4810072 | 12493 | -0.032 | -0.0033 | No | ||
128 | SET | 6650286 | 12672 | -0.037 | -0.0128 | No | ||
129 | SCFD2 | 2480504 | 12701 | -0.037 | -0.0142 | No | ||
130 | ELOVL4 | 5220333 | 13097 | -0.051 | -0.0355 | No | ||
131 | ENPP6 | 110524 580563 | 13110 | -0.052 | -0.0359 | No | ||
132 | MCM8 | 6130743 | 13120 | -0.052 | -0.0362 | No | ||
133 | GTF2A1 | 4120138 4920524 5390110 1230397 | 13282 | -0.059 | -0.0447 | No | ||
134 | SNCAIP | 4010551 | 13549 | -0.074 | -0.0588 | No | ||
135 | PPARGC1B | 3290114 | 13778 | -0.090 | -0.0709 | No | ||
136 | DAZL | 4050082 | 13812 | -0.092 | -0.0723 | No | ||
137 | TDRD1 | 4230301 6110750 | 13982 | -0.107 | -0.0811 | No | ||
138 | SNX5 | 1570021 6860609 | 14144 | -0.123 | -0.0893 | No | ||
139 | XRN2 | 130603 1230113 4230309 | 14174 | -0.125 | -0.0904 | No | ||
140 | LRP8 | 3610746 5360035 | 14182 | -0.127 | -0.0903 | No | ||
141 | GPX1 | 4150093 | 14283 | -0.141 | -0.0952 | No | ||
142 | ADCY3 | 2350347 3440242 | 14451 | -0.169 | -0.1036 | No | ||
143 | CDC14A | 4050132 | 14577 | -0.195 | -0.1096 | No | ||
144 | WEE1 | 3390070 | 14754 | -0.240 | -0.1182 | No | ||
145 | EEF1E1 | 4540711 | 14838 | -0.265 | -0.1217 | No | ||
146 | HOXA4 | 940152 | 15140 | -0.359 | -0.1366 | No | ||
147 | IVNS1ABP | 4760601 6520113 | 15287 | -0.418 | -0.1429 | No | ||
148 | SEMA7A | 2630239 5050593 | 15335 | -0.437 | -0.1438 | No | ||
149 | DAZAP1 | 5890563 | 15338 | -0.438 | -0.1422 | No | ||
150 | HSPA4 | 1050170 3450309 | 15448 | -0.501 | -0.1462 | No | ||
151 | CAMK4 | 1690091 | 15590 | -0.576 | -0.1516 | No | ||
152 | CENTB5 | 5690128 | 15600 | -0.582 | -0.1498 | No | ||
153 | EIF4E | 1580403 70133 6380215 | 15675 | -0.622 | -0.1514 | No | ||
154 | SLC31A2 | 1450577 | 15701 | -0.641 | -0.1503 | No | ||
155 | CRMP1 | 4810014 | 15915 | -0.758 | -0.1589 | No | ||
156 | EIF5A | 1500059 5290022 6370026 | 16008 | -0.822 | -0.1607 | No | ||
157 | CNOT4 | 2320242 6760706 | 16037 | -0.844 | -0.1589 | No | ||
158 | RPL19 | 5550592 | 16041 | -0.846 | -0.1558 | No | ||
159 | TEF | 1050050 3120397 4060487 | 16133 | -0.917 | -0.1572 | No | ||
160 | CLCN2 | 1940021 | 16136 | -0.919 | -0.1537 | No | ||
161 | PFN1 | 6130132 | 16156 | -0.934 | -0.1511 | No | ||
162 | EIF4G1 | 4070446 | 16163 | -0.938 | -0.1478 | No | ||
163 | EFNB1 | 2970433 | 16266 | -0.995 | -0.1495 | No | ||
164 | USP2 | 1190292 1240253 4850035 | 16298 | -1.004 | -0.1473 | No | ||
165 | SIRT1 | 1190731 | 16522 | -1.209 | -0.1547 | No | ||
166 | HSPH1 | 1690017 | 16694 | -1.368 | -0.1587 | No | ||
167 | MORF4L2 | 6450133 | 16753 | -1.436 | -0.1562 | No | ||
168 | MXD4 | 4810113 | 16871 | -1.587 | -0.1564 | No | ||
169 | MAX | 5220021 | 16906 | -1.643 | -0.1519 | No | ||
170 | PDK2 | 2690017 | 16927 | -1.663 | -0.1465 | No | ||
171 | RXRB | 1780040 5340438 | 16993 | -1.723 | -0.1434 | No | ||
172 | MAT2A | 4070026 4730079 6020280 | 17258 | -2.048 | -0.1498 | No | ||
173 | PTMA | 5570148 | 17343 | -2.177 | -0.1459 | No | ||
174 | ACVR2B | 1660546 | 17472 | -2.377 | -0.1436 | No | ||
175 | GNA13 | 4590102 | 17741 | -2.915 | -0.1468 | No | ||
176 | FCHSD2 | 5720092 | 17769 | -2.962 | -0.1368 | No | ||
177 | H3F3A | 2900086 | 17809 | -3.042 | -0.1271 | No | ||
178 | SLC20A1 | 6420014 | 17874 | -3.207 | -0.1182 | No | ||
179 | GABARAP | 1450286 | 17962 | -3.439 | -0.1095 | No | ||
180 | DIABLO | 2360170 | 18000 | -3.526 | -0.0979 | No | ||
181 | BCAS3 | 4050647 | 18111 | -3.842 | -0.0889 | No | ||
182 | WBP2 | 3170128 | 18364 | -5.139 | -0.0827 | No | ||
183 | PPP1R9B | 3130619 | 18386 | -5.338 | -0.0631 | No | ||
184 | BCL6 | 940100 | 18388 | -5.346 | -0.0424 | No | ||
185 | HSPBAP1 | 4060022 | 18512 | -6.429 | -0.0241 | No | ||
186 | RORC | 1740121 | 18573 | -7.664 | 0.0023 | No |