Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
Upregulated in class | truncNotch |
GeneSet | V$NMYC_01 |
Enrichment Score (ES) | 0.5286788 |
Normalized Enrichment Score (NES) | 1.4329286 |
Nominal p-value | 0.004524887 |
FDR q-value | 0.83052975 |
FWER p-Value | 0.996 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | VARS2 | 1410017 3800114 4210270 | 15 | 10.218 | 0.0456 | Yes | ||
2 | CEBPB | 2970019 | 19 | 9.933 | 0.0906 | Yes | ||
3 | G6PC3 | 1580487 5390253 | 24 | 9.367 | 0.1330 | Yes | ||
4 | FBL | 5130020 | 63 | 7.719 | 0.1660 | Yes | ||
5 | BCL7C | 460050 | 67 | 7.545 | 0.2002 | Yes | ||
6 | ATAD3A | 4050288 | 138 | 6.485 | 0.2259 | Yes | ||
7 | IPO4 | 5050619 | 199 | 5.881 | 0.2493 | Yes | ||
8 | ATP5G1 | 5290019 | 253 | 5.555 | 0.2717 | Yes | ||
9 | PA2G4 | 2030463 | 277 | 5.334 | 0.2947 | Yes | ||
10 | COPS7A | 3940458 7000022 | 299 | 5.204 | 0.3172 | Yes | ||
11 | HMOX1 | 1740687 | 484 | 4.425 | 0.3274 | Yes | ||
12 | VPS16 | 430064 3390041 6860301 | 570 | 4.133 | 0.3416 | Yes | ||
13 | PSEN2 | 130382 | 575 | 4.117 | 0.3601 | Yes | ||
14 | PRDX4 | 3800039 | 610 | 3.963 | 0.3762 | Yes | ||
15 | PPAT | 1980019 | 630 | 3.927 | 0.3931 | Yes | ||
16 | HSPE1 | 3170438 | 670 | 3.793 | 0.4082 | Yes | ||
17 | TIMM10 | 610070 1450019 | 680 | 3.769 | 0.4248 | Yes | ||
18 | ANXA6 | 2190014 | 882 | 3.265 | 0.4288 | Yes | ||
19 | EIF4B | 5390563 5270577 | 1080 | 2.905 | 0.4313 | Yes | ||
20 | HYAL2 | 1500152 | 1219 | 2.671 | 0.4360 | Yes | ||
21 | NOL5A | 5570139 | 1390 | 2.409 | 0.4377 | Yes | ||
22 | SH3KBP1 | 670102 2850458 7000309 | 1392 | 2.405 | 0.4486 | Yes | ||
23 | GPD1 | 2480095 | 1502 | 2.277 | 0.4530 | Yes | ||
24 | GTPBP1 | 2230541 4560528 | 1603 | 2.134 | 0.4573 | Yes | ||
25 | MYST3 | 5270500 | 1680 | 2.048 | 0.4625 | Yes | ||
26 | FKBP5 | 2190048 | 1785 | 1.947 | 0.4657 | Yes | ||
27 | HMGN2 | 3140091 | 1787 | 1.946 | 0.4745 | Yes | ||
28 | PABPC4 | 1990170 6760270 5390138 | 1804 | 1.930 | 0.4824 | Yes | ||
29 | FKBP10 | 1340706 | 1936 | 1.778 | 0.4834 | Yes | ||
30 | RPL22 | 4070070 | 1952 | 1.764 | 0.4906 | Yes | ||
31 | LMNB1 | 5890292 6020008 | 1995 | 1.723 | 0.4961 | Yes | ||
32 | TLE3 | 580040 4730121 | 2021 | 1.697 | 0.5025 | Yes | ||
33 | POLR3E | 380152 | 2025 | 1.692 | 0.5100 | Yes | ||
34 | DLX1 | 360168 | 2111 | 1.576 | 0.5126 | Yes | ||
35 | NR5A1 | 70707 | 2168 | 1.521 | 0.5164 | Yes | ||
36 | PABPC1 | 2650180 2690253 6020632 1990270 | 2199 | 1.494 | 0.5216 | Yes | ||
37 | IPO13 | 3870088 | 2301 | 1.411 | 0.5226 | Yes | ||
38 | SRP72 | 3990427 | 2307 | 1.408 | 0.5287 | Yes | ||
39 | AMPD2 | 630093 1170070 | 2538 | 1.171 | 0.5215 | No | ||
40 | DUSP4 | 2690044 2850593 | 2653 | 1.086 | 0.5203 | No | ||
41 | FHOD1 | 2680279 | 2670 | 1.072 | 0.5243 | No | ||
42 | KRTCAP2 | 5220040 | 2749 | 1.024 | 0.5247 | No | ||
43 | PES1 | 2470427 | 2843 | 0.985 | 0.5242 | No | ||
44 | ATP6V0B | 2810112 | 2957 | 0.914 | 0.5222 | No | ||
45 | GRK6 | 1500053 | 2999 | 0.884 | 0.5240 | No | ||
46 | HSPD1 | 60097 2030451 | 3056 | 0.843 | 0.5248 | No | ||
47 | GADD45G | 2510142 | 3166 | 0.773 | 0.5224 | No | ||
48 | ARF6 | 3520026 | 3174 | 0.768 | 0.5255 | No | ||
49 | CACNA1D | 1740315 4730731 | 3181 | 0.766 | 0.5286 | No | ||
50 | UBE1 | 4150139 7050463 | 3393 | 0.649 | 0.5201 | No | ||
51 | SCYL1 | 5050717 | 3408 | 0.641 | 0.5223 | No | ||
52 | AKAP10 | 2630504 5910577 | 3567 | 0.575 | 0.5163 | No | ||
53 | TPM2 | 520735 3870390 | 3689 | 0.528 | 0.5122 | No | ||
54 | NR1D1 | 2360471 770746 6590204 | 3902 | 0.461 | 0.5028 | No | ||
55 | BARHL1 | 4210113 | 4042 | 0.421 | 0.4972 | No | ||
56 | SLC38A5 | 540093 | 4156 | 0.391 | 0.4928 | No | ||
57 | DLC1 | 1090632 6450594 | 4172 | 0.387 | 0.4938 | No | ||
58 | SOCS5 | 3830398 7100093 | 4178 | 0.386 | 0.4952 | No | ||
59 | ELOVL6 | 5340746 | 4182 | 0.386 | 0.4968 | No | ||
60 | TIMM9 | 2450484 | 4219 | 0.376 | 0.4966 | No | ||
61 | LIG3 | 2940300 | 4302 | 0.354 | 0.4938 | No | ||
62 | B4GALT2 | 780037 | 4344 | 0.344 | 0.4931 | No | ||
63 | NRAS | 6900577 | 4377 | 0.338 | 0.4929 | No | ||
64 | RNF128 | 1230300 5670273 | 4447 | 0.327 | 0.4906 | No | ||
65 | CTSF | 6100021 | 4493 | 0.318 | 0.4896 | No | ||
66 | BAI2 | 380632 630113 6650170 | 4603 | 0.299 | 0.4851 | No | ||
67 | MNT | 4920575 | 4645 | 0.292 | 0.4842 | No | ||
68 | RAD9A | 110300 1940632 3990390 6040014 | 4716 | 0.279 | 0.4817 | No | ||
69 | TESK2 | 6520524 | 4751 | 0.273 | 0.4811 | No | ||
70 | RUNX2 | 1400193 4230215 | 4901 | 0.250 | 0.4741 | No | ||
71 | KCNK5 | 4590504 6860687 | 5194 | 0.214 | 0.4593 | No | ||
72 | TIAL1 | 4150048 6510605 | 5411 | 0.191 | 0.4484 | No | ||
73 | ADPRHL1 | 4150133 6650300 | 5437 | 0.187 | 0.4479 | No | ||
74 | DNMT3A | 4050068 4810717 | 5469 | 0.184 | 0.4471 | No | ||
75 | NXPH1 | 3870546 | 5494 | 0.181 | 0.4466 | No | ||
76 | BMP2K | 60541 5570504 | 5709 | 0.162 | 0.4357 | No | ||
77 | PLAGL1 | 3190082 6200193 | 6118 | 0.128 | 0.4142 | No | ||
78 | ETV1 | 70735 2940603 5080463 | 6155 | 0.127 | 0.4128 | No | ||
79 | MAPKAPK3 | 630520 | 6236 | 0.122 | 0.4090 | No | ||
80 | RTN4RL2 | 6450609 | 6518 | 0.107 | 0.3943 | No | ||
81 | DNAJB9 | 460114 | 6522 | 0.107 | 0.3946 | No | ||
82 | GPC3 | 6180735 | 6583 | 0.104 | 0.3918 | No | ||
83 | RPL13A | 2680519 5700142 | 6606 | 0.103 | 0.3911 | No | ||
84 | GRIN2A | 6550538 | 6647 | 0.101 | 0.3894 | No | ||
85 | SFXN2 | 2650563 3140095 3830762 3870398 | 6882 | 0.091 | 0.3771 | No | ||
86 | SOX12 | 1780037 | 6975 | 0.087 | 0.3725 | No | ||
87 | LAP3 | 2570064 | 7125 | 0.081 | 0.3648 | No | ||
88 | HS3ST3A1 | 2230497 | 7314 | 0.074 | 0.3549 | No | ||
89 | ARRDC3 | 4610390 | 7538 | 0.066 | 0.3431 | No | ||
90 | NKX2-2 | 4150731 | 7544 | 0.066 | 0.3432 | No | ||
91 | ADAMTS17 | 6510739 | 7746 | 0.061 | 0.3325 | No | ||
92 | GPS1 | 2470037 4760315 6200528 7100040 | 7795 | 0.060 | 0.3302 | No | ||
93 | CTBP2 | 430309 3710079 | 7921 | 0.056 | 0.3237 | No | ||
94 | NEUROD2 | 5290097 | 8301 | 0.047 | 0.3033 | No | ||
95 | POGK | 5290315 | 8408 | 0.045 | 0.2978 | No | ||
96 | NRXN1 | 460408 5340270 6370066 | 8423 | 0.044 | 0.2972 | No | ||
97 | JPH1 | 610739 | 8473 | 0.043 | 0.2948 | No | ||
98 | PCDHA10 | 3830725 | 8519 | 0.042 | 0.2925 | No | ||
99 | COL2A1 | 460446 3940500 | 8808 | 0.036 | 0.2771 | No | ||
100 | ANGPT2 | 1230458 5720706 6040605 | 8923 | 0.033 | 0.2710 | No | ||
101 | CHST11 | 6760546 | 8998 | 0.032 | 0.2672 | No | ||
102 | SC5DL | 6650390 | 9085 | 0.031 | 0.2626 | No | ||
103 | CUGBP1 | 450292 510022 7050176 7050215 | 9108 | 0.030 | 0.2616 | No | ||
104 | SLC12A5 | 1980692 | 9505 | 0.024 | 0.2402 | No | ||
105 | ADAM10 | 3780156 | 9517 | 0.023 | 0.2397 | No | ||
106 | HPCA | 6860010 | 9522 | 0.023 | 0.2396 | No | ||
107 | MTHFD1 | 5900398 6520427 | 9708 | 0.020 | 0.2297 | No | ||
108 | FLT3 | 2640487 | 9848 | 0.018 | 0.2222 | No | ||
109 | HOXB7 | 4540706 4610358 | 9973 | 0.016 | 0.2156 | No | ||
110 | KIAA0427 | 1690435 | 10029 | 0.015 | 0.2127 | No | ||
111 | ABCA1 | 6290156 | 10073 | 0.014 | 0.2104 | No | ||
112 | CHRM1 | 4280619 | 10310 | 0.010 | 0.1976 | No | ||
113 | PRKCE | 5700053 | 10501 | 0.007 | 0.1874 | No | ||
114 | RCL1 | 1980408 2680008 3800176 | 10519 | 0.007 | 0.1865 | No | ||
115 | FGF11 | 840292 | 10593 | 0.006 | 0.1825 | No | ||
116 | SEPT3 | 3830022 5290079 | 10724 | 0.003 | 0.1755 | No | ||
117 | NEUROD6 | 4670731 | 10794 | 0.002 | 0.1718 | No | ||
118 | ALX4 | 3870019 | 10815 | 0.002 | 0.1707 | No | ||
119 | LIN28 | 6590672 | 10871 | 0.001 | 0.1677 | No | ||
120 | B3GALT2 | 430136 | 11264 | -0.006 | 0.1465 | No | ||
121 | SGTB | 460170 | 11308 | -0.006 | 0.1442 | No | ||
122 | EIF3S1 | 6130368 6770044 | 11332 | -0.007 | 0.1430 | No | ||
123 | HOXC13 | 4070722 | 11553 | -0.011 | 0.1311 | No | ||
124 | SLC17A2 | 870593 2810035 | 11608 | -0.012 | 0.1282 | No | ||
125 | NPM1 | 4730427 | 12091 | -0.022 | 0.1022 | No | ||
126 | NUP153 | 7000452 | 12122 | -0.023 | 0.1006 | No | ||
127 | EN2 | 7000368 | 12197 | -0.025 | 0.0967 | No | ||
128 | LHX9 | 2350112 | 12245 | -0.026 | 0.0943 | No | ||
129 | PLA2G4A | 6380364 | 12255 | -0.026 | 0.0939 | No | ||
130 | POU3F1 | 3710022 | 12376 | -0.029 | 0.0876 | No | ||
131 | HHIP | 6940438 | 12397 | -0.030 | 0.0866 | No | ||
132 | APOA5 | 6130471 | 12497 | -0.032 | 0.0814 | No | ||
133 | SCFD2 | 2480504 | 12701 | -0.037 | 0.0706 | No | ||
134 | STMN4 | 2900091 | 12790 | -0.040 | 0.0660 | No | ||
135 | NDUFS1 | 2650253 | 12928 | -0.045 | 0.0587 | No | ||
136 | ENPP6 | 110524 580563 | 13110 | -0.052 | 0.0492 | No | ||
137 | MCM8 | 6130743 | 13120 | -0.052 | 0.0489 | No | ||
138 | SNCAIP | 4010551 | 13549 | -0.074 | 0.0260 | No | ||
139 | RBBP6 | 2320129 | 13725 | -0.086 | 0.0169 | No | ||
140 | PPARGC1B | 3290114 | 13778 | -0.090 | 0.0145 | No | ||
141 | PLAG1 | 1450142 3870139 6520039 | 13817 | -0.093 | 0.0129 | No | ||
142 | XRN2 | 130603 1230113 4230309 | 14174 | -0.125 | -0.0059 | No | ||
143 | ADCY3 | 2350347 3440242 | 14451 | -0.169 | -0.0201 | No | ||
144 | SEMA3F | 5420601 6770731 | 14497 | -0.178 | -0.0217 | No | ||
145 | CDC14A | 4050132 | 14577 | -0.195 | -0.0251 | No | ||
146 | WEE1 | 3390070 | 14754 | -0.240 | -0.0335 | No | ||
147 | TOP1 | 770471 4060632 6650324 | 14995 | -0.312 | -0.0451 | No | ||
148 | ZZZ3 | 780133 2320239 2640452 5080706 6550341 | 15034 | -0.321 | -0.0457 | No | ||
149 | HRH3 | 6180040 | 15133 | -0.356 | -0.0494 | No | ||
150 | RAMP2 | 6860037 | 15281 | -0.415 | -0.0555 | No | ||
151 | SEMA7A | 2630239 5050593 | 15335 | -0.437 | -0.0564 | No | ||
152 | PANK3 | 3060687 | 15411 | -0.482 | -0.0583 | No | ||
153 | U2AF2 | 450600 4670128 5420292 | 15479 | -0.519 | -0.0596 | No | ||
154 | ZCCHC7 | 6510592 | 15594 | -0.579 | -0.0631 | No | ||
155 | GADD45B | 2350408 | 15961 | -0.782 | -0.0794 | No | ||
156 | RBM3 | 2360739 5700167 | 16109 | -0.905 | -0.0833 | No | ||
157 | TEF | 1050050 3120397 4060487 | 16133 | -0.917 | -0.0803 | No | ||
158 | CLCN2 | 1940021 | 16136 | -0.919 | -0.0763 | No | ||
159 | HRSP12 | 610136 2510133 4280561 2760047 | 16142 | -0.923 | -0.0724 | No | ||
160 | BCL2 | 730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164 | 16152 | -0.932 | -0.0686 | No | ||
161 | PFN1 | 6130132 | 16156 | -0.934 | -0.0645 | No | ||
162 | EIF4G1 | 4070446 | 16163 | -0.938 | -0.0606 | No | ||
163 | HBP1 | 2510102 3130010 4210619 | 16288 | -1.001 | -0.0628 | No | ||
164 | USP2 | 1190292 1240253 4850035 | 16298 | -1.004 | -0.0587 | No | ||
165 | ZHX2 | 2900452 | 16477 | -1.164 | -0.0630 | No | ||
166 | MXD4 | 4810113 | 16871 | -1.587 | -0.0771 | No | ||
167 | MAX | 5220021 | 16906 | -1.643 | -0.0715 | No | ||
168 | PDK2 | 2690017 | 16927 | -1.663 | -0.0650 | No | ||
169 | RXRB | 1780040 5340438 | 16993 | -1.723 | -0.0607 | No | ||
170 | HTF9C | 3190048 4120132 | 17432 | -2.321 | -0.0739 | No | ||
171 | PFKFB3 | 630706 | 17720 | -2.857 | -0.0765 | No | ||
172 | GNA13 | 4590102 | 17741 | -2.915 | -0.0643 | No | ||
173 | SLC20A1 | 6420014 | 17874 | -3.207 | -0.0569 | No | ||
174 | AP1GBP1 | 2510372 | 17938 | -3.349 | -0.0451 | No | ||
175 | GJA1 | 5220731 | 17978 | -3.476 | -0.0314 | No | ||
176 | RPIA | 780079 | 18281 | -4.639 | -0.0267 | No | ||
177 | STAT3 | 460040 3710341 | 18295 | -4.709 | -0.0060 | No | ||
178 | WBP2 | 3170128 | 18364 | -5.139 | 0.0137 | No |