Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
Upregulated in class | truncNotch |
GeneSet | V$MAX_01 |
Enrichment Score (ES) | 0.41516668 |
Normalized Enrichment Score (NES) | 1.122882 |
Nominal p-value | 0.16542473 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | BAX | 3830008 | 36 | 8.812 | 0.0343 | Yes | ||
2 | CAD | 2340717 | 51 | 8.137 | 0.0670 | Yes | ||
3 | HMGA1 | 6580408 | 90 | 7.163 | 0.0943 | Yes | ||
4 | PFDN2 | 4230156 | 196 | 5.888 | 0.1129 | Yes | ||
5 | PA2G4 | 2030463 | 277 | 5.334 | 0.1304 | Yes | ||
6 | MRPL27 | 2060131 | 302 | 5.192 | 0.1505 | Yes | ||
7 | QTRT1 | 1340162 | 326 | 5.042 | 0.1700 | Yes | ||
8 | PTGES2 | 4210097 | 359 | 4.856 | 0.1882 | Yes | ||
9 | NUDC | 4780025 | 376 | 4.782 | 0.2070 | Yes | ||
10 | PLCG2 | 5720008 | 390 | 4.728 | 0.2257 | Yes | ||
11 | CFL1 | 2340735 | 427 | 4.620 | 0.2428 | Yes | ||
12 | ACY1 | 2360279 6550161 | 455 | 4.517 | 0.2599 | Yes | ||
13 | CLN3 | 780368 | 567 | 4.145 | 0.2709 | Yes | ||
14 | VPS16 | 430064 3390041 6860301 | 570 | 4.133 | 0.2878 | Yes | ||
15 | ASNA1 | 3830041 | 633 | 3.913 | 0.3005 | Yes | ||
16 | TIMM10 | 610070 1450019 | 680 | 3.769 | 0.3135 | Yes | ||
17 | NOTCH1 | 3390114 | 883 | 3.264 | 0.3160 | Yes | ||
18 | OPRS1 | 6130128 6290717 | 884 | 3.260 | 0.3294 | Yes | ||
19 | SUPT16H | 1240333 | 1061 | 2.936 | 0.3319 | Yes | ||
20 | PPRC1 | 1740441 | 1073 | 2.918 | 0.3433 | Yes | ||
21 | EIF4B | 5390563 5270577 | 1080 | 2.905 | 0.3549 | Yes | ||
22 | AATF | 5220575 | 1113 | 2.845 | 0.3649 | Yes | ||
23 | PSME3 | 2810537 | 1197 | 2.715 | 0.3715 | Yes | ||
24 | PER1 | 3290315 | 1425 | 2.364 | 0.3689 | Yes | ||
25 | TFRC | 4050551 | 1439 | 2.350 | 0.3779 | Yes | ||
26 | EEF1B2 | 4850400 6130161 | 1697 | 2.029 | 0.3723 | Yes | ||
27 | HNRPA1 | 4670398 5050687 | 1779 | 1.951 | 0.3759 | Yes | ||
28 | EIF2C2 | 770451 | 1822 | 1.913 | 0.3815 | Yes | ||
29 | HIRA | 4480609 5270167 | 1918 | 1.795 | 0.3837 | Yes | ||
30 | DDX3X | 2190020 | 1925 | 1.791 | 0.3908 | Yes | ||
31 | FKBP11 | 3170575 | 1950 | 1.765 | 0.3967 | Yes | ||
32 | TAF6L | 1850056 | 2037 | 1.678 | 0.3990 | Yes | ||
33 | AKAP12 | 1450739 | 2060 | 1.646 | 0.4045 | Yes | ||
34 | PABPC1 | 2650180 2690253 6020632 1990270 | 2199 | 1.494 | 0.4032 | Yes | ||
35 | DHX35 | 1230440 | 2231 | 1.476 | 0.4076 | Yes | ||
36 | IPO13 | 3870088 | 2301 | 1.411 | 0.4097 | Yes | ||
37 | SRP72 | 3990427 | 2307 | 1.408 | 0.4152 | Yes | ||
38 | AMPD2 | 630093 1170070 | 2538 | 1.171 | 0.4075 | No | ||
39 | RPS2 | 1340647 | 2585 | 1.142 | 0.4097 | No | ||
40 | COPZ1 | 6940100 | 2849 | 0.981 | 0.3995 | No | ||
41 | SLC38A2 | 1470242 3800026 | 2869 | 0.969 | 0.4024 | No | ||
42 | MRPL40 | 2370215 | 2885 | 0.957 | 0.4056 | No | ||
43 | GNAS | 630441 1850373 4050152 | 2945 | 0.924 | 0.4062 | No | ||
44 | RAB3IL1 | 380685 5420176 | 3297 | 0.702 | 0.3900 | No | ||
45 | CCAR1 | 3190092 | 3450 | 0.623 | 0.3843 | No | ||
46 | SNTB2 | 2630014 5390035 | 3640 | 0.541 | 0.3763 | No | ||
47 | TIMM8A | 110279 | 3753 | 0.508 | 0.3723 | No | ||
48 | EIF3S10 | 1190079 3840176 | 3899 | 0.462 | 0.3664 | No | ||
49 | SYT3 | 6380017 | 4018 | 0.428 | 0.3617 | No | ||
50 | SUCLG2 | 5340397 5700270 | 4053 | 0.419 | 0.3616 | No | ||
51 | GTF2H1 | 2570746 2650148 | 4099 | 0.405 | 0.3609 | No | ||
52 | SLC38A5 | 540093 | 4156 | 0.391 | 0.3594 | No | ||
53 | UBXD3 | 5050193 | 4163 | 0.390 | 0.3607 | No | ||
54 | ANAPC13 | 3800446 | 4475 | 0.321 | 0.3452 | No | ||
55 | ZNF318 | 5890091 6130021 | 4681 | 0.285 | 0.3352 | No | ||
56 | TESK2 | 6520524 | 4751 | 0.273 | 0.3326 | No | ||
57 | GNB2 | 2350053 | 4836 | 0.261 | 0.3291 | No | ||
58 | NEUROD1 | 3060619 | 4883 | 0.254 | 0.3277 | No | ||
59 | RUNX2 | 1400193 4230215 | 4901 | 0.250 | 0.3278 | No | ||
60 | OPRD1 | 4280138 | 5348 | 0.199 | 0.3044 | No | ||
61 | SLC26A2 | 2360278 | 5452 | 0.186 | 0.2996 | No | ||
62 | DNMT3A | 4050068 4810717 | 5469 | 0.184 | 0.2995 | No | ||
63 | NFX1 | 450504 | 5601 | 0.171 | 0.2931 | No | ||
64 | PPP1R3C | 2640170 | 5756 | 0.157 | 0.2854 | No | ||
65 | KCNE4 | 2470102 | 5807 | 0.152 | 0.2833 | No | ||
66 | ETV1 | 70735 2940603 5080463 | 6155 | 0.127 | 0.2650 | No | ||
67 | SYNCRIP | 1690195 3140113 4670279 | 6326 | 0.117 | 0.2563 | No | ||
68 | GUCY1A2 | 1660441 | 6803 | 0.094 | 0.2309 | No | ||
69 | PRKCH | 5720079 | 7131 | 0.080 | 0.2135 | No | ||
70 | RAI14 | 770288 1660075 | 7168 | 0.079 | 0.2118 | No | ||
71 | IRS4 | 430341 1190450 | 7184 | 0.078 | 0.2114 | No | ||
72 | EN1 | 5360168 7050025 | 7300 | 0.074 | 0.2054 | No | ||
73 | HOXC5 | 1580017 | 7420 | 0.070 | 0.1993 | No | ||
74 | CHD4 | 5420059 6130338 6380717 | 7662 | 0.063 | 0.1865 | No | ||
75 | NRIP3 | 1340372 | 7682 | 0.063 | 0.1857 | No | ||
76 | DSCAM | 1780050 2450731 2810438 | 7714 | 0.062 | 0.1843 | No | ||
77 | GGN | 1410528 4210082 5290170 | 7723 | 0.061 | 0.1841 | No | ||
78 | ADAMTS17 | 6510739 | 7746 | 0.061 | 0.1831 | No | ||
79 | ODC1 | 5670168 | 7800 | 0.059 | 0.1805 | No | ||
80 | STMN1 | 1990717 | 8289 | 0.047 | 0.1542 | No | ||
81 | SLC1A7 | 1990181 | 8339 | 0.046 | 0.1518 | No | ||
82 | POGK | 5290315 | 8408 | 0.045 | 0.1483 | No | ||
83 | PCDHA10 | 3830725 | 8519 | 0.042 | 0.1425 | No | ||
84 | HOXB5 | 2900538 | 8565 | 0.041 | 0.1402 | No | ||
85 | CPT1A | 6350093 | 8846 | 0.035 | 0.1252 | No | ||
86 | HOXD10 | 6100039 | 9393 | 0.025 | 0.0957 | No | ||
87 | XPO1 | 540707 | 9448 | 0.024 | 0.0929 | No | ||
88 | MTHFD1 | 5900398 6520427 | 9708 | 0.020 | 0.0789 | No | ||
89 | LZTFL1 | 540114 | 9808 | 0.018 | 0.0736 | No | ||
90 | ZBTB10 | 4200132 | 9918 | 0.017 | 0.0678 | No | ||
91 | HOXB7 | 4540706 4610358 | 9973 | 0.016 | 0.0649 | No | ||
92 | RCL1 | 1980408 2680008 3800176 | 10519 | 0.007 | 0.0354 | No | ||
93 | BCOR | 1660452 3940053 | 10650 | 0.005 | 0.0284 | No | ||
94 | HOXA11 | 6980133 | 10712 | 0.004 | 0.0251 | No | ||
95 | SEPT3 | 3830022 5290079 | 10724 | 0.003 | 0.0245 | No | ||
96 | LIN28 | 6590672 | 10871 | 0.001 | 0.0166 | No | ||
97 | ARMET | 5130670 | 11044 | -0.002 | 0.0073 | No | ||
98 | AKAP1 | 110148 1740735 2260019 7000563 | 11256 | -0.005 | -0.0041 | No | ||
99 | FGF14 | 2630390 3520075 6770048 | 11418 | -0.009 | -0.0128 | No | ||
100 | AP1S2 | 780279 4280707 | 11485 | -0.010 | -0.0164 | No | ||
101 | BMP6 | 2100128 | 11502 | -0.010 | -0.0172 | No | ||
102 | SSR1 | 5890100 | 11648 | -0.013 | -0.0250 | No | ||
103 | NPTX1 | 3710736 | 11852 | -0.017 | -0.0359 | No | ||
104 | NPM1 | 4730427 | 12091 | -0.022 | -0.0488 | No | ||
105 | ATOH8 | 4540204 | 12116 | -0.023 | -0.0500 | No | ||
106 | GATA5 | 430465 | 12143 | -0.023 | -0.0513 | No | ||
107 | ELAVL3 | 2850014 | 12594 | -0.035 | -0.0755 | No | ||
108 | NDUFS1 | 2650253 | 12928 | -0.045 | -0.0934 | No | ||
109 | FOXD3 | 6550156 | 13166 | -0.054 | -0.1060 | No | ||
110 | USP15 | 610592 3520504 | 13194 | -0.055 | -0.1073 | No | ||
111 | MEOX2 | 6400288 | 13401 | -0.065 | -0.1182 | No | ||
112 | TGFB2 | 4920292 | 13407 | -0.065 | -0.1182 | No | ||
113 | SNCAIP | 4010551 | 13549 | -0.074 | -0.1255 | No | ||
114 | CBX5 | 3830072 6290167 | 13658 | -0.081 | -0.1310 | No | ||
115 | SNX5 | 1570021 6860609 | 14144 | -0.123 | -0.1568 | No | ||
116 | UBE2B | 4780497 | 14201 | -0.128 | -0.1593 | No | ||
117 | GPX1 | 4150093 | 14283 | -0.141 | -0.1631 | No | ||
118 | DUSP7 | 2940309 | 14302 | -0.144 | -0.1635 | No | ||
119 | PICALM | 1940280 | 14430 | -0.165 | -0.1697 | No | ||
120 | TCERG1 | 2350551 4540397 5220746 | 14434 | -0.166 | -0.1692 | No | ||
121 | UBE4B | 780008 3610154 | 14528 | -0.185 | -0.1735 | No | ||
122 | PRPS1 | 6350129 | 14534 | -0.186 | -0.1730 | No | ||
123 | SUMF1 | 730050 | 14607 | -0.202 | -0.1760 | No | ||
124 | CSK | 6350593 | 14670 | -0.215 | -0.1785 | No | ||
125 | BOK | 1170373 5860446 | 14795 | -0.252 | -0.1842 | No | ||
126 | TOP1 | 770471 4060632 6650324 | 14995 | -0.312 | -0.1937 | No | ||
127 | TCF4 | 520021 | 15110 | -0.349 | -0.1985 | No | ||
128 | DVL2 | 6110162 | 15174 | -0.374 | -0.2003 | No | ||
129 | ATF4 | 730441 1740195 | 15175 | -0.374 | -0.1988 | No | ||
130 | COMMD3 | 2510259 | 15319 | -0.432 | -0.2048 | No | ||
131 | MTCH2 | 3780603 6620215 | 15359 | -0.451 | -0.2050 | No | ||
132 | ZCCHC7 | 6510592 | 15594 | -0.579 | -0.2153 | No | ||
133 | CENTB5 | 5690128 | 15600 | -0.582 | -0.2132 | No | ||
134 | EIF4E | 1580403 70133 6380215 | 15675 | -0.622 | -0.2147 | No | ||
135 | SLC31A2 | 1450577 | 15701 | -0.641 | -0.2134 | No | ||
136 | ATP6V1A | 6590242 | 16058 | -0.861 | -0.2291 | No | ||
137 | TCOF1 | 2680086 | 16071 | -0.874 | -0.2262 | No | ||
138 | EPC1 | 1570050 5290095 6900193 | 16244 | -0.985 | -0.2315 | No | ||
139 | HBP1 | 2510102 3130010 4210619 | 16288 | -1.001 | -0.2297 | No | ||
140 | HHEX | 2340575 | 16511 | -1.198 | -0.2368 | No | ||
141 | FEN1 | 1770541 | 16518 | -1.203 | -0.2322 | No | ||
142 | SIRT1 | 1190731 | 16522 | -1.209 | -0.2274 | No | ||
143 | CD164 | 3830594 | 16533 | -1.216 | -0.2229 | No | ||
144 | ATP6V1C1 | 2690324 5220528 | 16830 | -1.548 | -0.2326 | No | ||
145 | QTRTD1 | 7000053 | 16846 | -1.560 | -0.2270 | No | ||
146 | MXD4 | 4810113 | 16871 | -1.587 | -0.2218 | No | ||
147 | MAX | 5220021 | 16906 | -1.643 | -0.2169 | No | ||
148 | PDK2 | 2690017 | 16927 | -1.663 | -0.2111 | No | ||
149 | ILF3 | 940722 3190647 6520110 | 16952 | -1.684 | -0.2055 | No | ||
150 | TOPORS | 4060592 | 17123 | -1.872 | -0.2070 | No | ||
151 | ALDH6A1 | 1770746 | 17200 | -1.957 | -0.2031 | No | ||
152 | MAT2A | 4070026 4730079 6020280 | 17258 | -2.048 | -0.1978 | No | ||
153 | LAMP1 | 2470524 | 17305 | -2.122 | -0.1915 | No | ||
154 | PTMA | 5570148 | 17343 | -2.177 | -0.1846 | No | ||
155 | ATF7IP | 2690176 6770021 | 17399 | -2.275 | -0.1782 | No | ||
156 | SMAD2 | 4200592 | 17412 | -2.286 | -0.1695 | No | ||
157 | DUSP1 | 6860121 | 17511 | -2.443 | -0.1647 | No | ||
158 | DNAJB5 | 2900215 | 17773 | -2.967 | -0.1667 | No | ||
159 | BRDT | 3940102 | 17916 | -3.299 | -0.1608 | No | ||
160 | LZTS2 | 2260440 | 17920 | -3.303 | -0.1474 | No | ||
161 | GJA1 | 5220731 | 17978 | -3.476 | -0.1362 | No | ||
162 | HOXA7 | 5910152 | 17999 | -3.526 | -0.1228 | No | ||
163 | PPM1A | 1170301 5900273 | 18039 | -3.620 | -0.1100 | No | ||
164 | BCAS3 | 4050647 | 18111 | -3.842 | -0.0981 | No | ||
165 | KBTBD2 | 2320014 | 18277 | -4.613 | -0.0881 | No | ||
166 | ZFYVE26 | 6860152 | 18414 | -5.519 | -0.0728 | No | ||
167 | ISGF3G | 3190131 7100142 | 18497 | -6.228 | -0.0516 | No | ||
168 | NIT1 | 1230338 3940671 | 18499 | -6.238 | -0.0260 | No | ||
169 | CDK5R1 | 3870161 | 18581 | -7.857 | 0.0019 | No |