Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
Upregulated in class | truncNotch |
GeneSet | V$COUP_DR1_Q6 |
Enrichment Score (ES) | 0.4399161 |
Normalized Enrichment Score (NES) | 1.1926752 |
Nominal p-value | 0.099540584 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | FBLN1 | 2480059 5670735 | 29 | 9.066 | 0.0464 | Yes | ||
2 | WBSCR16 | 5570390 | 57 | 7.910 | 0.0867 | Yes | ||
3 | MRPL11 | 110215 | 159 | 6.258 | 0.1144 | Yes | ||
4 | TP53 | 6130707 | 231 | 5.694 | 0.1406 | Yes | ||
5 | SMYD5 | 6220025 | 251 | 5.584 | 0.1691 | Yes | ||
6 | MRPS28 | 2230373 | 268 | 5.433 | 0.1970 | Yes | ||
7 | PCBP4 | 6350722 | 298 | 5.205 | 0.2230 | Yes | ||
8 | TCEA2 | 6370546 | 406 | 4.663 | 0.2418 | Yes | ||
9 | ENO3 | 5270136 | 448 | 4.550 | 0.2637 | Yes | ||
10 | ZBTB12 | 1850079 | 464 | 4.486 | 0.2866 | Yes | ||
11 | SLC11A2 | 3140603 | 631 | 3.922 | 0.2983 | Yes | ||
12 | HSPE1 | 3170438 | 670 | 3.793 | 0.3163 | Yes | ||
13 | PRKAG1 | 6450091 | 1098 | 2.878 | 0.3084 | Yes | ||
14 | PDLIM7 | 4780136 | 1190 | 2.726 | 0.3179 | Yes | ||
15 | PSMF1 | 5340056 | 1209 | 2.679 | 0.3311 | Yes | ||
16 | PEX16 | 4560044 | 1355 | 2.449 | 0.3362 | Yes | ||
17 | PALM | 130601 3850017 | 1364 | 2.441 | 0.3486 | Yes | ||
18 | POLR2H | 5890242 | 1455 | 2.332 | 0.3561 | Yes | ||
19 | LRP1 | 6270386 | 1470 | 2.314 | 0.3676 | Yes | ||
20 | ATP5O | 7000398 | 1544 | 2.218 | 0.3754 | Yes | ||
21 | PDZK1 | 2320128 | 1625 | 2.106 | 0.3822 | Yes | ||
22 | EEF1B2 | 4850400 6130161 | 1697 | 2.029 | 0.3890 | Yes | ||
23 | NCDN | 50040 1980739 3520603 | 1793 | 1.942 | 0.3942 | Yes | ||
24 | RTN4 | 50725 630647 870097 870184 | 1799 | 1.934 | 0.4041 | Yes | ||
25 | PCTK1 | 4560079 | 1885 | 1.833 | 0.4092 | Yes | ||
26 | FGD2 | 5340195 | 1910 | 1.803 | 0.4174 | Yes | ||
27 | DCTN2 | 540471 3780717 | 1916 | 1.795 | 0.4267 | Yes | ||
28 | PRKACA | 2640731 4050048 | 2050 | 1.668 | 0.4283 | Yes | ||
29 | PAK4 | 1690152 | 2241 | 1.462 | 0.4257 | Yes | ||
30 | HIP2 | 2810095 3990369 4120301 | 2285 | 1.425 | 0.4309 | Yes | ||
31 | STOML2 | 1940487 | 2467 | 1.239 | 0.4277 | Yes | ||
32 | PRKCSH | 3360398 | 2527 | 1.179 | 0.4307 | Yes | ||
33 | TRAF4 | 3060041 4920528 6980286 | 2579 | 1.145 | 0.4340 | Yes | ||
34 | NR2F6 | 1340239 5670239 60338 4280088 | 2582 | 1.143 | 0.4399 | Yes | ||
35 | CXCL14 | 840114 6450324 | 2718 | 1.043 | 0.4381 | No | ||
36 | RQCD1 | 1850139 | 2922 | 0.938 | 0.4321 | No | ||
37 | HSPD1 | 60097 2030451 | 3056 | 0.843 | 0.4293 | No | ||
38 | MAGMAS | 580064 4920452 | 3086 | 0.825 | 0.4321 | No | ||
39 | ARF6 | 3520026 | 3174 | 0.768 | 0.4315 | No | ||
40 | NR2F1 | 4120528 360402 | 3271 | 0.714 | 0.4300 | No | ||
41 | HDAC11 | 2510242 | 3288 | 0.706 | 0.4329 | No | ||
42 | GBL | 2120161 5690086 | 3545 | 0.584 | 0.4221 | No | ||
43 | TPM2 | 520735 3870390 | 3689 | 0.528 | 0.4171 | No | ||
44 | PGF | 4810593 | 3740 | 0.512 | 0.4171 | No | ||
45 | NR2C1 | 2570605 | 3976 | 0.442 | 0.4067 | No | ||
46 | TOMM70A | 780114 | 4161 | 0.390 | 0.3988 | No | ||
47 | PRRX2 | 4260603 | 4293 | 0.356 | 0.3936 | No | ||
48 | HSD17B8 | 1940647 | 4513 | 0.314 | 0.3834 | No | ||
49 | SYTL2 | 580097 5390576 6770603 | 4527 | 0.312 | 0.3844 | No | ||
50 | OVOL1 | 1690131 | 4767 | 0.270 | 0.3728 | No | ||
51 | HOXA3 | 3610632 6020358 | 4903 | 0.250 | 0.3668 | No | ||
52 | NR2F2 | 3170609 3310577 | 5041 | 0.234 | 0.3606 | No | ||
53 | DPF3 | 2650128 2970168 | 5050 | 0.233 | 0.3614 | No | ||
54 | YBX2 | 3520441 | 5151 | 0.220 | 0.3572 | No | ||
55 | ESRRA | 6550242 | 5482 | 0.182 | 0.3403 | No | ||
56 | MYH10 | 2640673 | 5697 | 0.163 | 0.3295 | No | ||
57 | ERBB2 | 3830673 | 6585 | 0.104 | 0.2820 | No | ||
58 | TNRC4 | 4050156 | 6661 | 0.100 | 0.2785 | No | ||
59 | SALL1 | 5420020 7050195 | 6691 | 0.099 | 0.2774 | No | ||
60 | SLC39A5 | 2900100 4610440 | 6881 | 0.091 | 0.2677 | No | ||
61 | STMN2 | 6220181 | 6929 | 0.089 | 0.2656 | No | ||
62 | KIRREL3 | 2630195 | 7148 | 0.080 | 0.2542 | No | ||
63 | CLDN15 | 4150270 4730592 | 7210 | 0.077 | 0.2513 | No | ||
64 | SAP18 | 3610092 | 7383 | 0.071 | 0.2423 | No | ||
65 | ADAMTS19 | 2680739 | 7804 | 0.059 | 0.2199 | No | ||
66 | PAPLN | 2510592 | 7971 | 0.055 | 0.2112 | No | ||
67 | PIPOX | 70750 | 8066 | 0.053 | 0.2064 | No | ||
68 | PRODH2 | 630411 1400195 | 8084 | 0.052 | 0.2057 | No | ||
69 | TOM1L2 | 4810465 | 8238 | 0.048 | 0.1977 | No | ||
70 | F12 | 1090215 3520736 | 8258 | 0.048 | 0.1969 | No | ||
71 | TTR | 4150072 | 8561 | 0.041 | 0.1808 | No | ||
72 | GDNF | 4050487 5720739 | 8608 | 0.040 | 0.1785 | No | ||
73 | PTHR1 | 2640711 3360647 | 8669 | 0.039 | 0.1754 | No | ||
74 | CNTFR | 4480092 6200064 | 8719 | 0.038 | 0.1730 | No | ||
75 | PRDM13 | 1430022 | 8959 | 0.033 | 0.1602 | No | ||
76 | CYP26A1 | 380022 2690600 | 9012 | 0.032 | 0.1575 | No | ||
77 | IBRDC2 | 5130041 | 9069 | 0.031 | 0.1547 | No | ||
78 | TREX1 | 3450040 7100692 | 9164 | 0.029 | 0.1497 | No | ||
79 | CSF2 | 1660593 | 9269 | 0.028 | 0.1442 | No | ||
80 | NR4A1 | 6290161 | 9539 | 0.023 | 0.1298 | No | ||
81 | THPO | 2060286 | 9635 | 0.021 | 0.1247 | No | ||
82 | PAX6 | 1190025 | 9897 | 0.017 | 0.1107 | No | ||
83 | DMD | 1740041 3990332 | 10111 | 0.014 | 0.0992 | No | ||
84 | SLC26A3 | 380750 | 10130 | 0.013 | 0.0983 | No | ||
85 | CRABP2 | 6940725 | 10162 | 0.013 | 0.0967 | No | ||
86 | KCNE1L | 4670092 | 10175 | 0.013 | 0.0961 | No | ||
87 | TTYH1 | 3780672 5570520 | 10219 | 0.012 | 0.0938 | No | ||
88 | TPCN1 | 60458 6510731 6860601 | 10247 | 0.011 | 0.0924 | No | ||
89 | IRX6 | 4590025 | 10312 | 0.010 | 0.0890 | No | ||
90 | RNF139 | 2650114 3610450 | 10360 | 0.010 | 0.0865 | No | ||
91 | FABP1 | 6940035 | 10380 | 0.009 | 0.0855 | No | ||
92 | SS18 | 1940440 2900072 6900129 | 10506 | 0.007 | 0.0788 | No | ||
93 | POU5F1 | 450739 4560605 | 10638 | 0.005 | 0.0717 | No | ||
94 | PPARGC1A | 4670040 | 10672 | 0.004 | 0.0700 | No | ||
95 | EFEMP1 | 5860324 | 10742 | 0.003 | 0.0662 | No | ||
96 | HOXD3 | 6450154 | 10852 | 0.001 | 0.0603 | No | ||
97 | FOXA1 | 3710609 | 11195 | -0.005 | 0.0418 | No | ||
98 | HOXC13 | 4070722 | 11553 | -0.011 | 0.0225 | No | ||
99 | PRDM1 | 3170347 3520301 | 11777 | -0.016 | 0.0105 | No | ||
100 | MAP2K3 | 5570193 | 11952 | -0.019 | 0.0012 | No | ||
101 | CLCNKA | 1740050 | 12129 | -0.023 | -0.0082 | No | ||
102 | REST | 1500471 | 12219 | -0.025 | -0.0129 | No | ||
103 | APEX2 | 3780044 | 12276 | -0.026 | -0.0158 | No | ||
104 | PRDM16 | 4120541 | 12423 | -0.030 | -0.0236 | No | ||
105 | GOLGA4 | 460300 | 12490 | -0.032 | -0.0270 | No | ||
106 | EFNB3 | 5570594 | 12643 | -0.036 | -0.0350 | No | ||
107 | PAX7 | 6860593 | 12697 | -0.037 | -0.0377 | No | ||
108 | PNOC | 1990114 | 12703 | -0.038 | -0.0378 | No | ||
109 | UBE2R2 | 1230504 | 12806 | -0.040 | -0.0431 | No | ||
110 | OBSCN | 3610129 | 12817 | -0.041 | -0.0434 | No | ||
111 | NDUFS1 | 2650253 | 12928 | -0.045 | -0.0491 | No | ||
112 | FOXA3 | 2680121 | 13096 | -0.051 | -0.0579 | No | ||
113 | ARHGEF7 | 1690441 | 13151 | -0.053 | -0.0606 | No | ||
114 | WTAP | 4010176 | 13263 | -0.058 | -0.0663 | No | ||
115 | GPR124 | 510292 6290047 | 13271 | -0.059 | -0.0663 | No | ||
116 | LCAT | 6400441 | 13533 | -0.072 | -0.0801 | No | ||
117 | FXYD1 | 1400239 6560129 | 13724 | -0.086 | -0.0899 | No | ||
118 | RBBP6 | 2320129 | 13725 | -0.086 | -0.0895 | No | ||
119 | INSR | 1190504 | 13765 | -0.089 | -0.0911 | No | ||
120 | ACTA1 | 840538 | 14031 | -0.111 | -0.1049 | No | ||
121 | PPP1R14D | 2190168 | 14280 | -0.141 | -0.1176 | No | ||
122 | SLC16A9 | 6220497 | 14294 | -0.143 | -0.1175 | No | ||
123 | DNAJA2 | 2630253 6860358 | 14334 | -0.149 | -0.1189 | No | ||
124 | NR4A3 | 2900021 5860095 5910039 | 14450 | -0.169 | -0.1242 | No | ||
125 | AGPAT1 | 610056 | 14520 | -0.183 | -0.1270 | No | ||
126 | PRKCD | 770592 | 14588 | -0.197 | -0.1296 | No | ||
127 | CLSPN | 2190239 2630687 5550632 | 14672 | -0.215 | -0.1329 | No | ||
128 | SFRS6 | 60224 | 14710 | -0.226 | -0.1337 | No | ||
129 | NRAP | 1780433 | 14805 | -0.255 | -0.1375 | No | ||
130 | PKP3 | 3710048 | 14846 | -0.267 | -0.1382 | No | ||
131 | HMGCS2 | 770725 | 14967 | -0.302 | -0.1431 | No | ||
132 | COMMD3 | 2510259 | 15319 | -0.432 | -0.1599 | No | ||
133 | SHC1 | 2900731 3170504 6520537 | 15383 | -0.470 | -0.1608 | No | ||
134 | KLK6 | 4010706 870026 | 15398 | -0.477 | -0.1591 | No | ||
135 | AHCYL1 | 540609 | 15442 | -0.497 | -0.1588 | No | ||
136 | SLC26A6 | 4810575 | 15452 | -0.504 | -0.1566 | No | ||
137 | RRBP1 | 2260477 5050440 | 15475 | -0.515 | -0.1551 | No | ||
138 | AP1B1 | 4290373 | 15478 | -0.516 | -0.1524 | No | ||
139 | RFX1 | 540373 | 15575 | -0.567 | -0.1546 | No | ||
140 | GABARAPL2 | 610204 3360047 | 15586 | -0.575 | -0.1521 | No | ||
141 | PAPD4 | 1580673 730605 5270112 | 15599 | -0.582 | -0.1497 | No | ||
142 | UBE2D3 | 3190452 | 15655 | -0.609 | -0.1495 | No | ||
143 | USP37 | 2470433 | 15657 | -0.610 | -0.1463 | No | ||
144 | APOM | 2340010 | 15677 | -0.623 | -0.1440 | No | ||
145 | ZIC4 | 1500082 | 16045 | -0.848 | -0.1594 | No | ||
146 | ARFGEF2 | 5550500 | 16124 | -0.913 | -0.1588 | No | ||
147 | CLCN2 | 1940021 | 16136 | -0.919 | -0.1546 | No | ||
148 | PFN1 | 6130132 | 16156 | -0.934 | -0.1507 | No | ||
149 | LAMP2 | 1230402 1980373 | 16422 | -1.110 | -0.1592 | No | ||
150 | AGPS | 6980184 | 16725 | -1.403 | -0.1681 | No | ||
151 | SLC23A3 | 6840152 | 16754 | -1.439 | -0.1620 | No | ||
152 | ETFDH | 4670358 | 16755 | -1.441 | -0.1544 | No | ||
153 | SMAD3 | 6450671 | 16901 | -1.640 | -0.1536 | No | ||
154 | MAP3K11 | 7000039 | 17284 | -2.094 | -0.1632 | No | ||
155 | RBMS1 | 6400014 | 17294 | -2.106 | -0.1526 | No | ||
156 | EIF4EBP2 | 5670279 | 17337 | -2.170 | -0.1434 | No | ||
157 | DCTN1 | 1450056 6590022 | 17364 | -2.208 | -0.1331 | No | ||
158 | GLG1 | 3130021 | 17379 | -2.238 | -0.1220 | No | ||
159 | LMAN2L | 50079 6590100 6650338 | 17664 | -2.758 | -0.1228 | No | ||
160 | RNF5 | 2760088 | 17680 | -2.778 | -0.1089 | No | ||
161 | ZSWIM3 | 1230563 | 17744 | -2.920 | -0.0969 | No | ||
162 | BIN3 | 380551 | 17761 | -2.954 | -0.0821 | No | ||
163 | SCOTIN | 670332 3450167 6450022 | 17882 | -3.227 | -0.0716 | No | ||
164 | ZYX | 4730068 | 18001 | -3.527 | -0.0593 | No | ||
165 | USP52 | 3710215 6380133 | 18170 | -4.079 | -0.0469 | No | ||
166 | ALPI | 3940162 | 18518 | -6.524 | -0.0312 | No | ||
167 | HIBADH | 5550739 | 18539 | -6.887 | 0.0042 | No |