Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
Upregulated in class | truncNotch |
GeneSet | V$AP1_Q4 |
Enrichment Score (ES) | 0.41459498 |
Normalized Enrichment Score (NES) | 1.1394237 |
Nominal p-value | 0.1502146 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | LMNA | 520471 1500075 3190167 4210020 | 17 | 10.046 | 0.0447 | Yes | ||
2 | ABCB6 | 6350138 | 55 | 8.001 | 0.0790 | Yes | ||
3 | TAGLN2 | 4560121 | 100 | 6.921 | 0.1080 | Yes | ||
4 | CD151 | 1450592 3780309 | 140 | 6.481 | 0.1353 | Yes | ||
5 | RPL27A | 3130451 110195 6840494 | 195 | 5.913 | 0.1592 | Yes | ||
6 | EEF1A1 | 1980193 1990195 4670735 | 240 | 5.656 | 0.1825 | Yes | ||
7 | BAG2 | 2900324 | 368 | 4.822 | 0.1975 | Yes | ||
8 | CAPNS1 | 3940113 | 369 | 4.820 | 0.2194 | Yes | ||
9 | AKT1S1 | 1660048 | 579 | 4.103 | 0.2267 | Yes | ||
10 | PKN3 | 2260538 | 711 | 3.696 | 0.2364 | Yes | ||
11 | ELA1 | 3390167 | 832 | 3.366 | 0.2451 | Yes | ||
12 | ETV5 | 110017 | 844 | 3.337 | 0.2597 | Yes | ||
13 | PDGFRB | 6450279 | 930 | 3.165 | 0.2694 | Yes | ||
14 | GNGT2 | 540176 | 937 | 3.153 | 0.2834 | Yes | ||
15 | LIMK1 | 5080064 | 969 | 3.091 | 0.2958 | Yes | ||
16 | SYTL1 | 510487 | 1136 | 2.809 | 0.2995 | Yes | ||
17 | TNFRSF12A | 4810253 | 1193 | 2.721 | 0.3088 | Yes | ||
18 | BLMH | 1410438 | 1221 | 2.665 | 0.3195 | Yes | ||
19 | CDKN1A | 4050088 6400706 | 1374 | 2.431 | 0.3223 | Yes | ||
20 | RBBP7 | 430113 450450 2370309 | 1431 | 2.361 | 0.3299 | Yes | ||
21 | FKBP8 | 4060019 | 1476 | 2.307 | 0.3380 | Yes | ||
22 | CORO1C | 4570397 | 1479 | 2.301 | 0.3484 | Yes | ||
23 | TCF7 | 3800736 5390181 | 1528 | 2.244 | 0.3560 | Yes | ||
24 | DTX2 | 4210041 7000008 | 1666 | 2.058 | 0.3579 | Yes | ||
25 | RTN4 | 50725 630647 870097 870184 | 1799 | 1.934 | 0.3595 | Yes | ||
26 | COL27A1 | 1740390 | 1837 | 1.890 | 0.3661 | Yes | ||
27 | DCTN2 | 540471 3780717 | 1916 | 1.795 | 0.3700 | Yes | ||
28 | ABHD2 | 4850504 6840010 | 2013 | 1.704 | 0.3725 | Yes | ||
29 | POLR3E | 380152 | 2025 | 1.692 | 0.3796 | Yes | ||
30 | TGFBR2 | 1780711 1980537 6550398 | 2073 | 1.617 | 0.3844 | Yes | ||
31 | AP2A2 | 130082 | 2150 | 1.537 | 0.3872 | Yes | ||
32 | MAPK3 | 580161 4780035 | 2169 | 1.520 | 0.3931 | Yes | ||
33 | CIZ1 | 4150128 6130484 | 2304 | 1.410 | 0.3923 | Yes | ||
34 | UBQLN1 | 110280 730376 2470133 6590594 | 2322 | 1.390 | 0.3977 | Yes | ||
35 | ABHD4 | 6760450 | 2339 | 1.375 | 0.4030 | Yes | ||
36 | STOML2 | 1940487 | 2467 | 1.239 | 0.4018 | Yes | ||
37 | XPOT | 7050184 | 2477 | 1.223 | 0.4068 | Yes | ||
38 | IGFBP6 | 1580181 | 2479 | 1.222 | 0.4123 | Yes | ||
39 | MMP19 | 5080377 | 2541 | 1.170 | 0.4143 | Yes | ||
40 | IRAK1 | 4120593 | 2630 | 1.109 | 0.4146 | Yes | ||
41 | LAMB3 | 7100301 | 3104 | 0.816 | 0.3926 | No | ||
42 | APOBEC1 | 4610022 | 3156 | 0.777 | 0.3934 | No | ||
43 | SCRN1 | 6040025 6580019 | 3193 | 0.759 | 0.3949 | No | ||
44 | LTBP3 | 1190162 2650440 6520451 | 3199 | 0.757 | 0.3980 | No | ||
45 | VIM | 20431 | 3211 | 0.749 | 0.4009 | No | ||
46 | IL10 | 2340685 2640541 2850403 6590286 | 3254 | 0.720 | 0.4018 | No | ||
47 | TBC1D17 | 1780450 | 3394 | 0.649 | 0.3972 | No | ||
48 | DUSP13 | 6400152 | 3562 | 0.579 | 0.3908 | No | ||
49 | PTPRN | 5900577 | 3613 | 0.552 | 0.3906 | No | ||
50 | AK5 | 6290348 | 3679 | 0.532 | 0.3895 | No | ||
51 | FHL3 | 1090369 2650017 | 3699 | 0.524 | 0.3908 | No | ||
52 | ROM1 | 3130685 | 3704 | 0.524 | 0.3930 | No | ||
53 | CYFIP1 | 5690082 | 3861 | 0.473 | 0.3867 | No | ||
54 | CLSTN3 | 2350685 | 4147 | 0.394 | 0.3730 | No | ||
55 | NRAS | 6900577 | 4377 | 0.338 | 0.3621 | No | ||
56 | UBE2C | 6130017 | 4508 | 0.314 | 0.3565 | No | ||
57 | MDFI | 6200041 | 4561 | 0.306 | 0.3551 | No | ||
58 | GSN | 3830168 | 4731 | 0.277 | 0.3471 | No | ||
59 | PAPPA | 4230463 | 4805 | 0.264 | 0.3444 | No | ||
60 | NEFH | 630239 | 4847 | 0.259 | 0.3433 | No | ||
61 | HSPB7 | 1190441 | 4946 | 0.246 | 0.3391 | No | ||
62 | LAMC2 | 450692 2680041 4200059 4670148 | 5124 | 0.223 | 0.3305 | No | ||
63 | KCNN4 | 2680129 | 5181 | 0.216 | 0.3285 | No | ||
64 | TIAL1 | 4150048 6510605 | 5411 | 0.191 | 0.3169 | No | ||
65 | ADORA2A | 1990687 | 5423 | 0.189 | 0.3172 | No | ||
66 | GPR150 | 2570440 | 5459 | 0.185 | 0.3161 | No | ||
67 | GPR3 | 2970452 | 5582 | 0.174 | 0.3103 | No | ||
68 | RB1CC1 | 510494 7100072 | 5660 | 0.167 | 0.3069 | No | ||
69 | EEF1A2 | 2260162 5290086 | 5795 | 0.153 | 0.3003 | No | ||
70 | ESRRB | 3870082 | 5818 | 0.151 | 0.2998 | No | ||
71 | DNM1 | 1660097 5340519 | 5902 | 0.145 | 0.2960 | No | ||
72 | SLC16A6 | 1690156 | 5988 | 0.137 | 0.2920 | No | ||
73 | ZIC1 | 670113 | 6055 | 0.132 | 0.2890 | No | ||
74 | CASK | 2340215 3290576 6770215 | 6226 | 0.122 | 0.2803 | No | ||
75 | APBA2BP | 5700341 | 6229 | 0.122 | 0.2808 | No | ||
76 | XLKD1 | 520441 | 6252 | 0.120 | 0.2801 | No | ||
77 | PLAC1 | 2350594 | 6280 | 0.119 | 0.2792 | No | ||
78 | PAX9 | 3850519 | 6525 | 0.107 | 0.2664 | No | ||
79 | SHC3 | 2690398 | 6739 | 0.097 | 0.2553 | No | ||
80 | CCL22 | 6380086 | 6851 | 0.092 | 0.2497 | No | ||
81 | WDFY3 | 3610041 4560333 4570273 | 6987 | 0.086 | 0.2428 | No | ||
82 | UCHL3 | 1240735 | 7135 | 0.080 | 0.2352 | No | ||
83 | PTPRH | 3870070 | 7145 | 0.080 | 0.2350 | No | ||
84 | MAPRE3 | 7050504 | 7198 | 0.077 | 0.2326 | No | ||
85 | BTK | 3130044 | 7278 | 0.075 | 0.2286 | No | ||
86 | BMP2 | 6620687 | 7287 | 0.074 | 0.2285 | No | ||
87 | APOB48R | 2810070 | 7294 | 0.074 | 0.2285 | No | ||
88 | SH3RF2 | 6200600 | 7346 | 0.072 | 0.2261 | No | ||
89 | PTPRR | 130121 3990273 | 7385 | 0.071 | 0.2244 | No | ||
90 | EYA1 | 1450278 5220390 | 7397 | 0.070 | 0.2241 | No | ||
91 | LRP1B | 1450193 | 7542 | 0.066 | 0.2166 | No | ||
92 | NRIP3 | 1340372 | 7682 | 0.063 | 0.2093 | No | ||
93 | LPP | 1660541 | 7715 | 0.062 | 0.2079 | No | ||
94 | GGN | 1410528 4210082 5290170 | 7723 | 0.061 | 0.2078 | No | ||
95 | KBTBD5 | 6350025 | 7779 | 0.060 | 0.2050 | No | ||
96 | ST18 | 5720537 | 7781 | 0.060 | 0.2053 | No | ||
97 | DSTN | 3140592 | 7953 | 0.056 | 0.1962 | No | ||
98 | EPHA2 | 5890056 | 7986 | 0.055 | 0.1947 | No | ||
99 | TRIB1 | 2320435 | 8172 | 0.050 | 0.1849 | No | ||
100 | MMP7 | 1780497 | 8372 | 0.045 | 0.1743 | No | ||
101 | CMYA1 | 6900632 | 8397 | 0.045 | 0.1732 | No | ||
102 | LIFR | 3360068 3830102 | 8435 | 0.044 | 0.1714 | No | ||
103 | MYBPH | 2190711 | 8531 | 0.042 | 0.1665 | No | ||
104 | PADI3 | 6520072 | 8931 | 0.033 | 0.1450 | No | ||
105 | IL9 | 3440338 | 8978 | 0.033 | 0.1426 | No | ||
106 | IBRDC2 | 5130041 | 9069 | 0.031 | 0.1379 | No | ||
107 | SCOC | 610048 2230053 | 9674 | 0.021 | 0.1052 | No | ||
108 | GAB2 | 1410280 2340520 4280040 | 10136 | 0.013 | 0.0803 | No | ||
109 | BNIP3 | 3140270 | 10326 | 0.010 | 0.0700 | No | ||
110 | IL23A | 6290044 | 10396 | 0.009 | 0.0663 | No | ||
111 | CRYBA2 | 5900138 | 10466 | 0.008 | 0.0626 | No | ||
112 | FGF11 | 840292 | 10593 | 0.006 | 0.0558 | No | ||
113 | HOXA11 | 6980133 | 10712 | 0.004 | 0.0494 | No | ||
114 | HOXD3 | 6450154 | 10852 | 0.001 | 0.0419 | No | ||
115 | AP2B1 | 1450184 2370148 3520139 4850593 | 11213 | -0.005 | 0.0224 | No | ||
116 | IL1RN | 2370333 | 11222 | -0.005 | 0.0220 | No | ||
117 | GJB3 | 2650040 | 11235 | -0.005 | 0.0214 | No | ||
118 | AKAP1 | 110148 1740735 2260019 7000563 | 11256 | -0.005 | 0.0203 | No | ||
119 | USP13 | 1450670 | 11261 | -0.006 | 0.0201 | No | ||
120 | EIF3S1 | 6130368 6770044 | 11332 | -0.007 | 0.0163 | No | ||
121 | UCN2 | 4590372 | 11343 | -0.007 | 0.0158 | No | ||
122 | FAP | 4560019 | 11739 | -0.015 | -0.0055 | No | ||
123 | PRDM1 | 3170347 3520301 | 11777 | -0.016 | -0.0075 | No | ||
124 | S100A5 | 4120592 | 11954 | -0.019 | -0.0169 | No | ||
125 | GNAI1 | 4560390 | 12039 | -0.021 | -0.0214 | No | ||
126 | FGF12 | 1740446 2360037 | 12168 | -0.024 | -0.0282 | No | ||
127 | EDN1 | 1770047 | 12189 | -0.025 | -0.0292 | No | ||
128 | ANXA7 | 6110446 | 12473 | -0.031 | -0.0444 | No | ||
129 | GOLGA4 | 460300 | 12490 | -0.032 | -0.0451 | No | ||
130 | UBE3A | 1240152 2690438 5860609 | 12866 | -0.043 | -0.0653 | No | ||
131 | TRPV3 | 540341 | 13054 | -0.049 | -0.0752 | No | ||
132 | FBXW11 | 6450632 | 13105 | -0.052 | -0.0777 | No | ||
133 | PDAP1 | 1410735 | 13306 | -0.061 | -0.0883 | No | ||
134 | EVI2B | 1050465 | 13350 | -0.063 | -0.0903 | No | ||
135 | RAD23B | 2190671 | 13359 | -0.063 | -0.0905 | No | ||
136 | IL6 | 380133 | 13465 | -0.069 | -0.0958 | No | ||
137 | PCDH9 | 2100136 | 13564 | -0.075 | -0.1008 | No | ||
138 | EFNA1 | 3840672 | 13825 | -0.093 | -0.1145 | No | ||
139 | PDE4D | 2470528 6660014 | 13925 | -0.101 | -0.1194 | No | ||
140 | STAT5B | 6200026 | 13964 | -0.105 | -0.1210 | No | ||
141 | ROCK2 | 1780035 5720025 | 14051 | -0.113 | -0.1252 | No | ||
142 | RABEP1 | 4760427 6200463 | 14094 | -0.117 | -0.1269 | No | ||
143 | LRRC15 | 3940609 | 14156 | -0.124 | -0.1297 | No | ||
144 | LRRFIP2 | 670575 730152 6590438 | 14203 | -0.129 | -0.1316 | No | ||
145 | NEK6 | 3360687 | 14494 | -0.178 | -0.1465 | No | ||
146 | HS3ST3B1 | 380040 | 14741 | -0.236 | -0.1588 | No | ||
147 | RIN1 | 510593 | 14765 | -0.243 | -0.1589 | No | ||
148 | SFN | 6290301 7510608 | 14842 | -0.266 | -0.1618 | No | ||
149 | STX17 | 2260037 | 15011 | -0.316 | -0.1695 | No | ||
150 | HDAC3 | 4060072 | 15017 | -0.317 | -0.1683 | No | ||
151 | VDR | 130156 510438 | 15057 | -0.329 | -0.1690 | No | ||
152 | PSMD11 | 2340538 6510053 | 15097 | -0.345 | -0.1695 | No | ||
153 | MAP1A | 4920576 | 15164 | -0.372 | -0.1714 | No | ||
154 | MAP2K1 | 840739 | 15572 | -0.564 | -0.1909 | No | ||
155 | EIF4E | 1580403 70133 6380215 | 15675 | -0.622 | -0.1936 | No | ||
156 | AKT3 | 1580270 3290278 | 15891 | -0.742 | -0.2019 | No | ||
157 | PITPNC1 | 3990017 | 15965 | -0.787 | -0.2023 | No | ||
158 | ARRDC4 | 2810019 | 15995 | -0.810 | -0.2002 | No | ||
159 | ZIC4 | 1500082 | 16045 | -0.848 | -0.1990 | No | ||
160 | ICK | 1580746 3140021 | 16086 | -0.887 | -0.1972 | No | ||
161 | LAPTM5 | 5550372 | 16128 | -0.915 | -0.1952 | No | ||
162 | EIF4G1 | 4070446 | 16163 | -0.938 | -0.1928 | No | ||
163 | PSMA3 | 5900047 7040161 | 16279 | -1.000 | -0.1945 | No | ||
164 | USP2 | 1190292 1240253 4850035 | 16298 | -1.004 | -0.1909 | No | ||
165 | BACH1 | 290195 | 16344 | -1.040 | -0.1887 | No | ||
166 | NFRKB | 3130538 | 16417 | -1.105 | -0.1876 | No | ||
167 | TCF12 | 3610324 7000156 | 16445 | -1.131 | -0.1839 | No | ||
168 | CREM | 840156 6380438 6660041 6660168 | 16504 | -1.193 | -0.1816 | No | ||
169 | PSMD4 | 430068 | 16882 | -1.603 | -0.1948 | No | ||
170 | AXIN2 | 3850131 | 16894 | -1.628 | -0.1880 | No | ||
171 | MCART1 | 5270059 | 16946 | -1.677 | -0.1832 | No | ||
172 | ELK3 | 460377 1400762 3710497 | 17008 | -1.735 | -0.1786 | No | ||
173 | USP3 | 2060332 | 17095 | -1.832 | -0.1749 | No | ||
174 | PIM2 | 840136 5720692 7100577 | 17219 | -1.989 | -0.1726 | No | ||
175 | BAZ2A | 730184 | 17471 | -2.373 | -0.1754 | No | ||
176 | SRPK2 | 6380341 | 17551 | -2.521 | -0.1683 | No | ||
177 | MMP9 | 580338 | 17812 | -3.049 | -0.1685 | No | ||
178 | ISG20 | 1770750 | 17937 | -3.348 | -0.1601 | No | ||
179 | RPA3 | 5700136 | 18113 | -3.845 | -0.1521 | No | ||
180 | CMAS | 2190129 | 18184 | -4.113 | -0.1372 | No | ||
181 | TRIM8 | 6130441 | 18257 | -4.536 | -0.1205 | No | ||
182 | CAMKK1 | 6370324 | 18360 | -5.128 | -0.1028 | No | ||
183 | PPP1R9B | 3130619 | 18386 | -5.338 | -0.0799 | No | ||
184 | LAMC1 | 4730025 | 18437 | -5.753 | -0.0565 | No | ||
185 | ABI3 | 1740563 | 18540 | -6.889 | -0.0308 | No | ||
186 | KCNH2 | 1170451 | 18574 | -7.677 | 0.0023 | No |