Details for gene set PGC[GSEA]

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos
Phenotype	phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos
Upregulated in class	truncNotch
GeneSet	PGC
Enrichment Score (ES)	0.569609
Normalized Enrichment Score (NES)	1.6263156
Nominal p-value	0.0
FDR q-value	0.067129396
FWER p-Value	0.771

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	COMT	360687 510577 5700092	3	12.727	0.0230	Yes
2	PKM2	6520403 70500	8	11.751	0.0441	Yes
3	RANGNRF	5270520	27	9.218	0.0599	Yes
4	GUK1	5900059	32	8.897	0.0758	Yes
5	MRPS18B	5570086	62	7.759	0.0883	Yes
6	PUS1	2120736	65	7.652	0.1021	Yes
7	RUVBL2	1190377	74	7.395	0.1151	Yes
8	MAPKAPK2	2850500	104	6.885	0.1261	Yes
9	TIMM13	2450601	115	6.699	0.1377	Yes
10	SOD2	1410053	158	6.275	0.1468	Yes
11	MRPL11	110215	159	6.258	0.1582	Yes
12	SHMT1	5900132	175	6.070	0.1684	Yes
13	UNG	3130110 6100364	191	5.927	0.1783	Yes
14	ACADS	110746	215	5.784	0.1876	Yes
15	ADSL	5570484	223	5.722	0.1976	Yes
16	MRPL4	2680050	236	5.673	0.2073	Yes
17	ETFB	2690025	247	5.606	0.2169	Yes
18	CLPP	6520102	256	5.540	0.2265	Yes
19	MRPS18A	6770433	261	5.492	0.2363	Yes
20	LDHA	2190594	263	5.481	0.2462	Yes
21	TCIRG1	4590524 5910079 6900619	283	5.312	0.2548	Yes
22	CYC1	2850546	286	5.279	0.2643	Yes
23	PSMB10	630504 6510039	303	5.190	0.2728	Yes
24	PMM1	6840112	316	5.084	0.2814	Yes
25	PTGES2	4210097	359	4.856	0.2880	Yes
26	UQCRC1	520053	374	4.792	0.2959	Yes
27	PFKM	1990156 5720168	383	4.761	0.3041	Yes
28	TPI1	1500215 2100154	397	4.690	0.3119	Yes
29	APBA3	2510348	446	4.563	0.3176	Yes
30	MDH2	1850601	514	4.312	0.3218	Yes
31	ABCA2	5050039	520	4.296	0.3293	Yes
32	TXN2	2030402	529	4.280	0.3367	Yes
33	MTX1	5910059 6550181	559	4.190	0.3427	Yes
34	NINJ1	4480039	562	4.174	0.3502	Yes
35	GSTO1	6650600	656	3.856	0.3521	Yes
36	GSS	6130465 6900398	664	3.830	0.3587	Yes
37	HSPE1	3170438	670	3.793	0.3653	Yes
38	AGPAT3	60152	699	3.728	0.3705	Yes
39	TOMM40	6110017	745	3.621	0.3747	Yes
40	MT2A	6860286	774	3.542	0.3796	Yes
41	BAT3	1990594	775	3.541	0.3860	Yes
42	PGAM1	2570133	776	3.540	0.3924	Yes
43	PSMB5	6290242	805	3.437	0.3971	Yes
44	SCD	2680441	817	3.413	0.4027	Yes
45	NDUFA8	3460491	821	3.403	0.4088	Yes
46	SKIV2L	3780278 4570092	849	3.332	0.4133	Yes
47	PIGQ	4540286 1450452	875	3.281	0.4179	Yes
48	FXC1	3710053 4060575	906	3.217	0.4221	Yes
49	PGLS	2120324	922	3.187	0.4271	Yes
50	PDGFRB	6450279	930	3.165	0.4325	Yes
51	ECGF1	1990685	932	3.161	0.4382	Yes
52	MRPL34	3520605	971	3.086	0.4417	Yes
53	GCH1	670364 6550358	978	3.072	0.4470	Yes
54	TUFM	3290685	979	3.072	0.4525	Yes
55	ENO1	5340128	1000	3.040	0.4570	Yes
56	PPM1G	610725	1038	2.968	0.4604	Yes
57	PTDSS2	4200019	1056	2.942	0.4648	Yes
58	BSG	2900193 6520053	1063	2.933	0.4698	Yes
59	DGAT1	1850538	1117	2.836	0.4720	Yes
60	ABCF1	2630707 2760273 3520725	1159	2.767	0.4748	Yes
61	NDUFS3	1690136 5340528	1172	2.750	0.4792	Yes
62	ICT1	430138	1179	2.743	0.4838	Yes
63	PSME3	2810537	1197	2.715	0.4878	Yes
64	SGTA	3940154	1257	2.610	0.4893	Yes
65	STK19	3120070 6620300 6660136	1328	2.502	0.4901	Yes
66	NDUFB5	110685	1334	2.493	0.4943	Yes
67	GTPBP4	6840332	1345	2.469	0.4983	Yes
68	MRPS34	5700541	1359	2.446	0.5020	Yes
69	S100A1	6770707	1407	2.385	0.5038	Yes
70	MRPS12	4210707 6110341	1412	2.383	0.5079	Yes
71	TFRC	4050551	1439	2.350	0.5107	Yes
72	IDH3G	6860706	1480	2.301	0.5127	Yes
73	GPX4	5080433	1490	2.294	0.5164	Yes
74	ATP5O	7000398	1544	2.218	0.5175	Yes
75	DDT	4590398	1546	2.214	0.5215	Yes
76	ABHD5	6510273	1616	2.113	0.5216	Yes
77	SPP1	2470609	1662	2.060	0.5229	Yes
78	DBI	1090706	1676	2.049	0.5259	Yes
79	MRPL20	2640494	1714	2.012	0.5275	Yes
80	PGK1	1570494 630300	1768	1.961	0.5282	Yes
81	FOXM1	6650402 6980091	1770	1.958	0.5317	Yes
82	BID	4590592 6130008	1783	1.950	0.5346	Yes
83	PRDX2	6760095 4010619 5340577	1784	1.947	0.5381	Yes
84	RTN4	50725 630647 870097 870184	1799	1.934	0.5409	Yes
85	EIF3S6IP	870041 6770400	1818	1.917	0.5434	Yes
86	VDAC3	5390088	1896	1.818	0.5425	Yes
87	COX5B	6550670	1951	1.765	0.5427	Yes
88	POLR2E	2900348 3360348	2009	1.706	0.5427	Yes
89	MRPS2	5860725	2014	1.704	0.5456	Yes
90	P4HA2	1090546	2044	1.674	0.5470	Yes
91	TNNI3	7000093	2046	1.673	0.5500	Yes
92	SUPV3L1	1170072	2097	1.591	0.5502	Yes
93	NDRG2	450403	2101	1.584	0.5529	Yes
94	SDHB	3120398 4780113 3710435	2156	1.530	0.5527	Yes
95	NDUFA6	3990348	2161	1.527	0.5553	Yes
96	DNAJA3	1980671 6220338	2226	1.478	0.5545	Yes
97	ITPK1	3360056	2249	1.458	0.5559	Yes
98	TIMM17A	130092	2262	1.446	0.5579	Yes
99	PSMA5	5390537	2263	1.443	0.5605	Yes
100	ATP5A1	1990722	2302	1.410	0.5610	Yes
101	NDUFS5	4010692	2343	1.374	0.5613	Yes
102	RAMP3	4060215	2350	1.371	0.5635	Yes
103	PSMB7	5570088 5890647	2362	1.360	0.5654	Yes
104	IDH3A	460332	2364	1.357	0.5678	Yes
105	TCN2	2810139	2376	1.344	0.5696	Yes
106	SLC25A11	130097 770685	2424	1.283	0.5694	No
107	DFFA	2850215	2651	1.087	0.5590	No
108	KCNN1	4200725	2763	1.016	0.5548	No
109	FASTK	2690053 4280288 4610551 6370292	2776	1.009	0.5560	No
110	CYCS	2030072	2866	0.970	0.5529	No
111	MRPL40	2370215	2885	0.957	0.5536	No
112	MRPL46	360736	2924	0.936	0.5533	No
113	ACO2	4230600	2940	0.926	0.5541	No
114	ITPR2	5360128	2965	0.907	0.5545	No
115	MTHFD2	3800411	2985	0.894	0.5550	No
116	CS	5080600	3021	0.868	0.5547	No
117	HSPD1	60097 2030451	3056	0.843	0.5544	No
118	CHRNE	3190170	3067	0.836	0.5554	No
119	EDNRA	6900133	3137	0.791	0.5530	No
120	FABP3	6860452	3152	0.780	0.5537	No
121	DOM3Z	2360068 3870358	3153	0.779	0.5551	No
122	EIF4A2	1170494 1740711 2850504	3212	0.749	0.5533	No
123	MRPS17	4670156	3324	0.686	0.5485	No
124	SLC25A4	2360519	3436	0.629	0.5436	No
125	ERO1L	3060242 4780154 5220075	3645	0.539	0.5332	No
126	SMPD1	1410309 5550717	3665	0.535	0.5331	No
127	ALAS1	6400440	3728	0.515	0.5307	No
128	TIMM8A	110279	3753	0.508	0.5303	No
129	PCOLCE	4210433	3758	0.507	0.5310	No
130	GRPEL1	3180240	3792	0.496	0.5301	No
131	LRPPRC	2370072 2470408	3884	0.467	0.5259	No
132	PCTK3	1500328	3885	0.467	0.5268	No
133	RRM1	4150433	3904	0.461	0.5267	No
134	IDH2	2680397	3986	0.438	0.5230	No
135	UROD	2470494	4057	0.417	0.5200	No
136	MRPL13	1660215 2850551	4085	0.410	0.5192	No
137	PRDX3	1690035	4236	0.373	0.5117	No
138	ATP5C1	5910601	4241	0.371	0.5122	No
139	TIMM23	60288 7040133	4251	0.367	0.5123	No
140	USP8	2640347 3840451 6100672	4489	0.319	0.5000	No
141	CTSF	6100021	4493	0.318	0.5004	No
142	NME7	60170 1230551 2850333 4200102 4560411 5090647	4568	0.305	0.4969	No
143	CA2	1660113 1660600	4747	0.273	0.4877	No
144	HSPA5	5130671	4803	0.264	0.4852	No
145	CRAT	540020 2060364 3520148	4806	0.264	0.4855	No
146	COX7C	2470047	4881	0.255	0.4819	No
147	CA4	130100	4907	0.250	0.4810	No
148	SEPX1	3710041 5270403	4965	0.244	0.4784	No
149	MFN1	5080546 6200292	5206	0.213	0.4656	No
150	SCN1B	1240022 2120048	5402	0.193	0.4553	No
151	ESRRA	6550242	5482	0.182	0.4514	No
152	LRP5	2100397 3170484	5590	0.173	0.4458	No
153	FRAP1	2850037 6660010	5700	0.163	0.4402	No
154	PCYT2	2630092 4590278	5716	0.161	0.4397	No
155	CDC34	1190152 4570451	5766	0.155	0.4373	No
156	EEF1A2	2260162 5290086	5795	0.153	0.4360	No
157	COX7B	2340504	5943	0.141	0.4282	No
158	RRM2	6350059 6940162	5949	0.140	0.4282	No
159	F2RL2	6110736	6001	0.136	0.4257	No
160	FZD4	1580520	6048	0.133	0.4234	No
161	AK1	130605	6066	0.132	0.4227	No
162	DLD	4150403 6590341	6289	0.118	0.4108	No
163	UQCRB	1450047	6430	0.112	0.4034	No
164	DNAJB9	460114	6522	0.107	0.3986	No
165	DHX16	940044	6528	0.107	0.3985	No
166	SOD3	1410484	6570	0.105	0.3965	No
167	COX6A1	1050095 1450239	7027	0.084	0.3717	No
168	FOS	1850315	7375	0.071	0.3529	No
169	IFI16	6520601	7495	0.068	0.3465	No
170	OSBPL1A	770168 2850687 3780079 7050487	7506	0.068	0.3461	No
171	PHYH	6380128	7588	0.065	0.3418	No
172	NDRG4	6510685	7618	0.064	0.3403	No
173	CX3CL1	3990707	7685	0.063	0.3368	No
174	PCK1	7000358	7734	0.061	0.3343	No
175	PSMA6	50609	7761	0.060	0.3330	No
176	PGM1	3840408	8006	0.054	0.3198	No
177	MTX2	6660288	8025	0.054	0.3189	No
178	POPDC2	2030056	8152	0.050	0.3121	No
179	PDK4	6400300	8334	0.046	0.3023	No
180	MYH11	7100273	8367	0.046	0.3006	No
181	HCCS	670397 3170341	8437	0.044	0.2969	No
182	DPYSL3	1580594	8748	0.038	0.2801	No
183	CKMT2	1580288	8756	0.037	0.2798	No
184	CPT1A	6350093	8846	0.035	0.2750	No
185	MYL2	70471	8863	0.035	0.2742	No
186	VIPR1	2480292 5720288 6760537	8895	0.034	0.2725	No
187	ACYP2	2510605	8963	0.033	0.2689	No
188	MKRN3	1340270	9129	0.030	0.2600	No
189	ARVCF	2190537	9465	0.024	0.2417	No
190	LPIN1	1770358 3120059	9507	0.024	0.2395	No
191	ACYP1	6380403	9622	0.022	0.2333	No
192	NDUFB3	4610687	9793	0.019	0.2241	No
193	ATP2A3	130440 2190451	9873	0.017	0.2198	No
194	PDCD6	4760239	9896	0.017	0.2186	No
195	GYS1	540154	9912	0.017	0.2178	No
196	HMGB3	2940168	9924	0.016	0.2173	No
197	PYGM	3940300	10158	0.013	0.2046	No
198	LRBA	3450402	10601	0.006	0.1804	No
199	NR0B2	2470692	10637	0.005	0.1785	No
200	PDXK	6840066	10868	0.001	0.1660	No
201	ARMET	5130670	11044	-0.002	0.1564	No
202	FDX1	4050215	11084	-0.003	0.1543	No
203	CNOT7	2450338 5720397	11221	-0.005	0.1469	No
204	AKAP1	110148 1740735 2260019 7000563	11256	-0.005	0.1450	No
205	GABPA	2360017 4780301 4850279	11719	-0.015	0.1198	No
206	SLC2A4	540441	11889	-0.018	0.1106	No
207	MPP5	2100148 5220632	11903	-0.018	0.1100	No
208	SACM1L	3190446	11923	-0.019	0.1090	No
209	MAP2K3	5570193	11952	-0.019	0.1075	No
210	CKS2	1410156	12021	-0.021	0.1038	No
211	GCDH	2190324 4280347	12148	-0.024	0.0969	No
212	TFB2M	3830161 4670059 4760184	12242	-0.025	0.0919	No
213	AMACR	780215	12341	-0.028	0.0866	No
214	SDHA	7000056	12362	-0.029	0.0856	No
215	MAL	4280487 4590239	12634	-0.035	0.0708	No
216	SLC25A20	3190427	12680	-0.037	0.0684	No
217	PTPRD	520008 3120097	12987	-0.047	0.0518	No
218	NPPB	4150722	13022	-0.048	0.0500	No
219	NFS1	1170465 2680563	13055	-0.049	0.0484	No
220	ACTR2	1170332	13149	-0.053	0.0434	No
221	SUCLG1	1850082 5290270	13154	-0.053	0.0433	No
222	SRC	580132	13241	-0.057	0.0387	No
223	UPP1	3850358 3940100	13251	-0.058	0.0383	No
224	SH3BGR	840400	13462	-0.069	0.0270	No
225	COX7A1	6770427	13501	-0.071	0.0250	No
226	MAT2B	1690139 2510706	13685	-0.083	0.0152	No
227	NFYC	1400746	13690	-0.083	0.0151	No
228	HADHB	60064 2690670	13927	-0.101	0.0024	No
229	SPINT1	3190059	14022	-0.111	-0.0025	No
230	UBE2B	4780497	14201	-0.128	-0.0120	No
231	LRRFIP2	670575 730152 6590438	14203	-0.129	-0.0118	No
232	STARD7	270139 940497	14224	-0.131	-0.0127	No
233	SLC31A1	4590161 6940154	14358	-0.154	-0.0197	No
234	GOLPH3	2370195 6980711	14371	-0.156	-0.0201	No
235	IFRD1	4590215	14547	-0.188	-0.0293	No
236	NCAM1	3140026	14572	-0.194	-0.0302	No
237	NOLA3	6940687	14589	-0.197	-0.0307	No
238	NDUFAB1	1980091	14627	-0.205	-0.0324	No
239	CARHSP1	3390402	14929	-0.293	-0.0483	No
240	SUCLA2	730632 1170292	14993	-0.312	-0.0512	No
241	SNW1	4010736	15056	-0.328	-0.0540	No
242	MRPL39	7000161	15184	-0.379	-0.0602	No
243	LCN2	2510112	15190	-0.380	-0.0598	No
244	VAMP8	380411 1190139	15290	-0.420	-0.0644	No
245	MTCH2	3780603 6620215	15359	-0.451	-0.0673	No
246	GHITM	3290092	15391	-0.473	-0.0682	No
247	PFKP	70138 6760040 1170278	15394	-0.474	-0.0674	No
248	UBC	1190129 1570161 5390079 6770097 7100500	15408	-0.481	-0.0672	No
249	GBAS	6760278	15539	-0.545	-0.0734	No
250	MAP2K1	840739	15572	-0.564	-0.0741	No
251	PSCA	2450161	15618	-0.590	-0.0755	No
252	S100A13	520019	15656	-0.610	-0.0764	No
253	PIB5PA	6900427	15659	-0.611	-0.0754	No
254	TIMM8B	1190364	15698	-0.639	-0.0763	No
255	COX7A2	4280114	15775	-0.674	-0.0792	No
256	BNIP3L	1940347	15806	-0.692	-0.0796	No
257	PDHB	70215 610086	15820	-0.698	-0.0790	No
258	MRPL15	360390	15852	-0.721	-0.0794	No
259	CRMP1	4810014	15915	-0.758	-0.0814	No
260	MRPL18	6560341	16013	-0.824	-0.0852	No
261	TSC2	1450494	16043	-0.847	-0.0853	No
262	THEM2	6840746	16165	-0.941	-0.0902	No
263	COPS3	780039	16181	-0.953	-0.0893	No
264	SPTLC2	6840324 520017	16239	-0.985	-0.0906	No
265	RAB40C	840309	16258	-0.993	-0.0898	No
266	AES	6550333 6180484	16289	-1.001	-0.0896	No
267	USP2	1190292 1240253 4850035	16298	-1.004	-0.0882	No
268	PDHA1	5550397	16299	-1.004	-0.0864	No
269	COL7A1	1230168 2190072	16388	-1.078	-0.0892	No
270	SLC25A5	1980672	16442	-1.126	-0.0901	No
271	NDUFA5	5720239 6550035	16483	-1.169	-0.0901	No
272	NDUFC1	2570377 4200239	16500	-1.190	-0.0888	No
273	STK16	1740154	16542	-1.226	-0.0888	No
274	GRSF1	2100184	16549	-1.235	-0.0869	No
275	RANGAP1	2320593 6650601	16596	-1.280	-0.0871	No
276	NSF	4070075	16705	-1.383	-0.0905	No
277	ACADL	6420044 6860025	16745	-1.429	-0.0900	No
278	TBL1X	6400524	16796	-1.501	-0.0900	No
279	MAPK8	2640195	16851	-1.569	-0.0901	No
280	ARIH1	6900025	16973	-1.702	-0.0936	No
281	RXRB	1780040 5340438	16993	-1.723	-0.0916	No
282	EGLN1	2480180 3120253 6110195	17009	-1.736	-0.0892	No
283	TTC1	5890736	17327	-2.149	-0.1026	No
284	TIMM44	4670746 4730050	17357	-2.197	-0.1002	No
285	SLC12A7	6860079	17361	-2.201	-0.0964	No
286	DUSP1	6860121	17511	-2.443	-0.1001	No
287	NFIX	2450152	17552	-2.521	-0.0977	No
288	RNF5	2760088	17680	-2.778	-0.0996	No
289	LSM8	460068	17694	-2.809	-0.0952	No
290	ATP1A1	5670451	17702	-2.827	-0.0904	No
291	GNA13	4590102	17741	-2.915	-0.0872	No
292	DUSP6	5910286 7100070	17846	-3.147	-0.0872	No
293	SLC20A1	6420014	17874	-3.207	-0.0828	No
294	GATA3	6130068	17892	-3.243	-0.0778	No
295	ULK1	6100315	17957	-3.420	-0.0751	No
296	GABARAPL1	2810458	17968	-3.447	-0.0694	No
297	PHLDA1	2450020	18090	-3.769	-0.0692	No
298	RPA3	5700136	18113	-3.845	-0.0634	No
299	ACADM	460112 3390113	18158	-4.046	-0.0584	No
300	FBS1	2570520	18237	-4.416	-0.0547	No
301	ATP6V1D	2120037	18246	-4.483	-0.0470	No
302	CDKN2D	6040035	18458	-5.892	-0.0478	No
303	CRLF3	6620019	18473	-5.996	-0.0376	No
304	ATP1B1	3130594	18480	-6.052	-0.0270	No
305	GTPBP2	2760750	18494	-6.206	-0.0164	No
306	NGFRAP1	6770195	18496	-6.208	-0.0052	No
307	GTF2H4	3520100	18511	-6.425	0.0057	No