Details for gene set HSA04660_T_CELL_RECEPTOR_SIGNALING

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos
Phenotype	phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos
Upregulated in class	normalThy
GeneSet	HSA04660_T_CELL_RECEPTOR_SIGNALING_PATHWAY
Enrichment Score (ES)	-0.5924187
Normalized Enrichment Score (NES)	-1.5852388
Nominal p-value	0.005249344
FDR q-value	0.36513525
FWER p-Value	0.989

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PIK3R2	1660193	606	3.975	-0.0026	No
2	NFKBIB	2260167	770	3.547	0.0154	No
3	HRAS	1980551	798	3.458	0.0401	No
4	ZAP70	1410494 2260504	1024	2.988	0.0505	No
5	PDCD1	4120082	1409	2.385	0.0478	No
6	NFKB1	5420358	1663	2.059	0.0498	No
7	GRB2	6650398	1856	1.865	0.0535	No
8	RASGRP1	1050148 4050632 6510671	2163	1.527	0.0485	No
9	PAK4	1690152	2241	1.462	0.0554	No
10	NFATC1	510400 2320348 4050600 6180161 6290136 6620086	2365	1.357	0.0590	No
11	CDK4	540075 4540600	2750	1.023	0.0461	No
12	PPP3R1	1190041 1570487	2809	0.997	0.0505	No
13	PTPN6	4230128	3027	0.864	0.0453	No
14	IL10	2340685 2640541 2850403 6590286	3254	0.720	0.0385	No
15	PIK3R3	1770333	3593	0.560	0.0245	No
16	CDC42	1240168 3440278 4480519 5290162	3752	0.508	0.0198	No
17	GRAP2	7100441 1410647	3859	0.474	0.0177	No
18	NRAS	6900577	4377	0.338	-0.0076	No
19	PTPRC	130402 5290148	4545	0.309	-0.0143	No
20	IL4	6020537	4994	0.240	-0.0367	No
21	PIK3CD	3060546	5286	0.205	-0.0509	No
22	IL5	6370364 1050193	5609	0.171	-0.0669	No
23	PPP3CA	4760332 6760092	5932	0.142	-0.0832	No
24	PPP3R2	7000154	6096	0.130	-0.0911	No
25	PIK3R1	4730671	7309	0.074	-0.1559	No
26	FOS	1850315	7375	0.071	-0.1589	No
27	CBLC	50152	7689	0.063	-0.1753	No
28	SOS1	7050338	7718	0.062	-0.1764	No
29	CBLB	3520465 4670348	7847	0.058	-0.1828	No
30	NFKBIE	580390 2190086	8369	0.045	-0.2106	No
31	PAK7	3830164	8919	0.034	-0.2400	No
32	NCK1	6200575 6510050	8925	0.033	-0.2400	No
33	CSF2	1660593	9269	0.028	-0.2583	No
34	AKT1	5290746	9328	0.027	-0.2612	No
35	IL2	1770725	9836	0.018	-0.2885	No
36	PLCG1	6020369	9889	0.017	-0.2911	No
37	PAK3	4210136	9921	0.016	-0.2927	No
38	NFATC2	70450 540097	10515	0.007	-0.3246	No
39	PRKCQ	2260170 3870193	11611	-0.012	-0.3837	No
40	CD40LG	3120270	11851	-0.017	-0.3964	No
41	NFATC4	2470735	11895	-0.018	-0.3986	No
42	PPP3CC	2450139	12057	-0.021	-0.4071	No
43	AKT2	3850541 3870519	12186	-0.025	-0.4139	No
44	TNF	6650603	12392	-0.029	-0.4247	No
45	IFNG	5670592	12899	-0.044	-0.4517	No
46	JUN	840170	13860	-0.095	-0.5028	No
47	PIK3CA	6220129	13874	-0.096	-0.5028	No
48	PAK1	4540315	13880	-0.097	-0.5023	No
49	NFAT5	2510411 5890195 6550152	14931	-0.293	-0.5567	No
50	MALT1	4670292	14981	-0.308	-0.5571	No
51	IKBKG	3450092 3840377 6590592	15489	-0.523	-0.5805	No
52	NFKB2	2320670	15676	-0.622	-0.5858	No
53	VAV3	1050731 2450242 2680653	15709	-0.646	-0.5826	No
54	AKT3	1580270 3290278	15891	-0.742	-0.5868	Yes
55	FYN	2100468 4760520 4850687	15896	-0.745	-0.5814	Yes
56	PIK3R5	1090056	15924	-0.763	-0.5771	Yes
57	NCK2	2510010	15978	-0.794	-0.5739	Yes
58	VAV2	3610725 5890717	15989	-0.803	-0.5684	Yes
59	MAP3K8	2940286	16052	-0.854	-0.5653	Yes
60	SOS2	2060722	16061	-0.863	-0.5592	Yes
61	ICOS	1190048	16064	-0.868	-0.5527	Yes
62	LCP2	2680066 6650707	16263	-0.994	-0.5559	Yes
63	CD8B	1940411 2570035	16471	-1.157	-0.5583	Yes
64	LAT	3170025	16561	-1.244	-0.5537	Yes
65	RHOA	580142 5900131 5340450	16657	-1.337	-0.5487	Yes
66	CTLA4	6590537	16670	-1.347	-0.5392	Yes
67	KRAS	2060170	16854	-1.572	-0.5372	Yes
68	PPP3CB	6020156	16865	-1.582	-0.5258	Yes
69	IKBKB	6840072	16924	-1.659	-0.5163	Yes
70	PIK3CG	5890110	16947	-1.678	-0.5048	Yes
71	LCK	3360142	17003	-1.730	-0.4947	Yes
72	CHUK	7050736	17108	-1.856	-0.4863	Yes
73	PIK3CB	3800600	17306	-2.122	-0.4809	Yes
74	CD3D	2810739	17311	-2.126	-0.4650	Yes
75	PAK2	360438 7050068	17539	-2.495	-0.4584	Yes
76	NFATC3	5050520	17626	-2.654	-0.4430	Yes
77	CD28	1400739 4210093	17714	-2.847	-0.4261	Yes
78	PDK1	5290427	17798	-3.019	-0.4078	Yes
79	NFKBIA	1570152	17856	-3.162	-0.3869	Yes
80	CARD11	70338	17860	-3.175	-0.3631	Yes
81	CBL	6380068	18068	-3.711	-0.3462	Yes
82	VAV1	6020487	18073	-3.720	-0.3183	Yes
83	BCL10	2360397	18081	-3.744	-0.2903	Yes
84	MAP3K14	5890435	18190	-4.158	-0.2647	Yes
85	CD3E	3800056	18329	-4.901	-0.2351	Yes
86	CD4	1090010	18448	-5.828	-0.1974	Yes
87	CD247	3800725 5720136	18455	-5.882	-0.1532	Yes
88	CD3G	2680288	18503	-6.298	-0.1081	Yes
89	TEC	1400576	18565	-7.453	-0.0551	Yes
90	ITK	2230592	18571	-7.638	0.0024	Yes