Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
Upregulated in class | truncNotch |
GeneSet | REACTOME_DIABETES_PATHWAYS |
Enrichment Score (ES) | 0.6065688 |
Normalized Enrichment Score (NES) | 1.6210706 |
Nominal p-value | 0.0 |
FDR q-value | 0.051411096 |
FWER p-Value | 0.552 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PKM2 | 6520403 70500 | 8 | 11.751 | 0.0486 | Yes | ||
2 | RPL38 | 70040 4060138 6200601 | 13 | 10.322 | 0.0915 | Yes | ||
3 | RPS19 | 5860066 | 151 | 6.362 | 0.1107 | Yes | ||
4 | RPL27A | 3130451 110195 6840494 | 195 | 5.913 | 0.1331 | Yes | ||
5 | F2 | 5720280 | 204 | 5.849 | 0.1571 | Yes | ||
6 | ETFB | 2690025 | 247 | 5.606 | 0.1782 | Yes | ||
7 | ATP5G1 | 5290019 | 253 | 5.555 | 0.2011 | Yes | ||
8 | NDUFA10 | 5570347 | 327 | 5.039 | 0.2182 | Yes | ||
9 | ATP5E | 4120411 | 333 | 4.999 | 0.2388 | Yes | ||
10 | DDOST | 2680731 | 364 | 4.837 | 0.2574 | Yes | ||
11 | UQCRC1 | 520053 | 374 | 4.792 | 0.2769 | Yes | ||
12 | TPI1 | 1500215 2100154 | 397 | 4.690 | 0.2953 | Yes | ||
13 | RPS24 | 5420377 | 471 | 4.467 | 0.3100 | Yes | ||
14 | MDH2 | 1850601 | 514 | 4.312 | 0.3258 | Yes | ||
15 | NDUFB8 | 2260450 | 542 | 4.253 | 0.3421 | Yes | ||
16 | SSR4 | 1340619 4150132 | 602 | 3.983 | 0.3555 | Yes | ||
17 | ATP5D | 6550167 | 642 | 3.882 | 0.3696 | Yes | ||
18 | RPS3A | 2470086 | 710 | 3.700 | 0.3814 | Yes | ||
19 | NDUFS2 | 4850020 6200402 | 742 | 3.628 | 0.3949 | Yes | ||
20 | UQCR | 6130025 | 747 | 3.610 | 0.4098 | Yes | ||
21 | NDUFA8 | 3460491 | 821 | 3.403 | 0.4200 | Yes | ||
22 | NDUFB10 | 5900576 | 853 | 3.319 | 0.4322 | Yes | ||
23 | NDUFV1 | 5420369 | 859 | 3.313 | 0.4458 | Yes | ||
24 | RPL14 | 5080471 | 1019 | 2.997 | 0.4497 | Yes | ||
25 | NDUFS3 | 1690136 5340528 | 1172 | 2.750 | 0.4529 | Yes | ||
26 | NDUFS8 | 4150100 | 1174 | 2.747 | 0.4644 | Yes | ||
27 | RPS23 | 7100594 | 1205 | 2.684 | 0.4739 | Yes | ||
28 | NDUFB7 | 1850026 | 1231 | 2.649 | 0.4837 | Yes | ||
29 | SSR2 | 5390180 | 1308 | 2.522 | 0.4901 | Yes | ||
30 | NDUFB5 | 110685 | 1334 | 2.493 | 0.4991 | Yes | ||
31 | IDH3G | 6860706 | 1480 | 2.301 | 0.5009 | Yes | ||
32 | COX8A | 3780500 | 1485 | 2.298 | 0.5103 | Yes | ||
33 | ATP5O | 7000398 | 1544 | 2.218 | 0.5164 | Yes | ||
34 | NDUFA7 | 5900722 | 1610 | 2.118 | 0.5217 | Yes | ||
35 | SEC61G | 4120725 | 1656 | 2.066 | 0.5279 | Yes | ||
36 | SDHD | 2570128 | 1664 | 2.059 | 0.5361 | Yes | ||
37 | ATP5I | 6220047 | 1721 | 2.004 | 0.5415 | Yes | ||
38 | PGK1 | 1570494 630300 | 1768 | 1.961 | 0.5472 | Yes | ||
39 | MBTPS1 | 1230273 4850152 6860605 | 1833 | 1.898 | 0.5516 | Yes | ||
40 | NDUFA11 | 3780333 | 1881 | 1.841 | 0.5568 | Yes | ||
41 | COX5B | 6550670 | 1951 | 1.765 | 0.5604 | Yes | ||
42 | NDUFS7 | 1740142 | 2018 | 1.698 | 0.5639 | Yes | ||
43 | SDHB | 3120398 4780113 3710435 | 2156 | 1.530 | 0.5629 | Yes | ||
44 | NDUFA6 | 3990348 | 2161 | 1.527 | 0.5690 | Yes | ||
45 | ATP5J | 4210100 6900288 | 2216 | 1.484 | 0.5723 | Yes | ||
46 | ATP5A1 | 1990722 | 2302 | 1.410 | 0.5736 | Yes | ||
47 | SRP72 | 3990427 | 2307 | 1.408 | 0.5793 | Yes | ||
48 | NDUFS5 | 4010692 | 2343 | 1.374 | 0.5831 | Yes | ||
49 | NDUFC2 | 580075 | 2349 | 1.371 | 0.5886 | Yes | ||
50 | IDH3A | 460332 | 2364 | 1.357 | 0.5935 | Yes | ||
51 | IGFBP6 | 1580181 | 2479 | 1.222 | 0.5924 | Yes | ||
52 | RPS3 | 1570017 2370170 | 2481 | 1.221 | 0.5975 | Yes | ||
53 | RPL18A | 4570619 | 2535 | 1.176 | 0.5995 | Yes | ||
54 | RPS2 | 1340647 | 2585 | 1.142 | 0.6016 | Yes | ||
55 | SRP19 | 780450 3120075 | 2633 | 1.104 | 0.6037 | Yes | ||
56 | COX6B1 | 3710440 6180438 | 2679 | 1.067 | 0.6057 | Yes | ||
57 | CYCS | 2030072 | 2866 | 0.970 | 0.5997 | Yes | ||
58 | ATP5F1 | 7000725 | 2904 | 0.946 | 0.6016 | Yes | ||
59 | GNAS | 630441 1850373 4050152 | 2945 | 0.924 | 0.6033 | Yes | ||
60 | RPS17 | 2360528 | 3012 | 0.873 | 0.6034 | Yes | ||
61 | CS | 5080600 | 3021 | 0.868 | 0.6066 | Yes | ||
62 | ATP5J2 | 2630706 | 3432 | 0.630 | 0.5870 | No | ||
63 | PRKCA | 6400551 | 3491 | 0.607 | 0.5864 | No | ||
64 | SEC61B | 840113 4540687 | 3517 | 0.594 | 0.5875 | No | ||
65 | PFKFB2 | 3940538 7100059 | 3528 | 0.590 | 0.5894 | No | ||
66 | RPS15A | 1170180 | 3573 | 0.570 | 0.5894 | No | ||
67 | CPE | 2940441 | 3595 | 0.559 | 0.5906 | No | ||
68 | IGFBP5 | 2360592 | 3749 | 0.510 | 0.5845 | No | ||
69 | RPS4X | 2690020 | 3784 | 0.500 | 0.5847 | No | ||
70 | IGF1 | 1990193 3130377 3290280 | 3811 | 0.487 | 0.5853 | No | ||
71 | IGFBP4 | 2680309 5420441 | 4138 | 0.396 | 0.5693 | No | ||
72 | ATP5C1 | 5910601 | 4241 | 0.371 | 0.5653 | No | ||
73 | SLC2A2 | 5130537 5720722 6770079 | 4454 | 0.326 | 0.5552 | No | ||
74 | RPL37A | 7040717 | 4468 | 0.322 | 0.5559 | No | ||
75 | NDUFA9 | 2260280 | 4528 | 0.311 | 0.5540 | No | ||
76 | RPL4 | 2940014 5420324 | 4592 | 0.302 | 0.5518 | No | ||
77 | CTSL1 | 2350519 | 4659 | 0.289 | 0.5494 | No | ||
78 | RPS13 | 1570364 | 4688 | 0.283 | 0.5491 | No | ||
79 | FAU | 7100465 | 4776 | 0.269 | 0.5455 | No | ||
80 | HSPA5 | 5130671 | 4803 | 0.264 | 0.5452 | No | ||
81 | COX7C | 2470047 | 4881 | 0.255 | 0.5421 | No | ||
82 | RPL6 | 6040735 | 5220 | 0.211 | 0.5247 | No | ||
83 | VAMP2 | 2100100 | 5268 | 0.207 | 0.5230 | No | ||
84 | GLP1R | 6420528 | 5275 | 0.206 | 0.5235 | No | ||
85 | RPSA | 2360408 2680736 | 5502 | 0.180 | 0.5120 | No | ||
86 | KCNJ11 | 2510131 | 5596 | 0.172 | 0.5077 | No | ||
87 | UQCRFS1 | 6620576 | 5632 | 0.170 | 0.5065 | No | ||
88 | COX7B | 2340504 | 5943 | 0.141 | 0.4903 | No | ||
89 | KLF4 | 1850022 3830239 5570750 | 6095 | 0.130 | 0.4827 | No | ||
90 | DLD | 4150403 6590341 | 6289 | 0.118 | 0.4727 | No | ||
91 | PLA2G7 | 4730092 | 6292 | 0.118 | 0.4731 | No | ||
92 | ABCC8 | 2810671 3120671 | 6349 | 0.116 | 0.4706 | No | ||
93 | UQCRB | 1450047 | 6430 | 0.112 | 0.4667 | No | ||
94 | PFKFB1 | 2370128 | 6572 | 0.105 | 0.4595 | No | ||
95 | PCSK2 | 360017 430528 5900619 | 6777 | 0.095 | 0.4488 | No | ||
96 | EIF2S1 | 5360292 | 6844 | 0.092 | 0.4456 | No | ||
97 | COX6A1 | 1050095 1450239 | 7027 | 0.084 | 0.4361 | No | ||
98 | RPL17 | 2690167 5690504 | 7449 | 0.069 | 0.4136 | No | ||
99 | NDUFB4 | 460348 5690594 | 7527 | 0.067 | 0.4097 | No | ||
100 | NKX2-2 | 4150731 | 7544 | 0.066 | 0.4091 | No | ||
101 | GCG | 6220735 | 7914 | 0.056 | 0.3894 | No | ||
102 | ERN1 | 2360403 | 8131 | 0.051 | 0.3779 | No | ||
103 | ADRA2A | 5340520 | 8583 | 0.041 | 0.3536 | No | ||
104 | SRP54 | 2970605 | 9095 | 0.030 | 0.3261 | No | ||
105 | PDX1 | 6660647 | 9580 | 0.023 | 0.2999 | No | ||
106 | KIF5B | 770397 5420168 | 9643 | 0.021 | 0.2967 | No | ||
107 | NDUFB3 | 4610687 | 9793 | 0.019 | 0.2887 | No | ||
108 | IGFBP1 | 5720435 | 10500 | 0.007 | 0.2505 | No | ||
109 | LEP | 4010053 | 10635 | 0.005 | 0.2432 | No | ||
110 | SYT5 | 4150082 | 10691 | 0.004 | 0.2403 | No | ||
111 | EXOC5 | 7000711 | 10889 | 0.001 | 0.2296 | No | ||
112 | RAP1A | 1090025 | 11113 | -0.003 | 0.2175 | No | ||
113 | RPL18 | 6380181 3870195 | 11277 | -0.006 | 0.2087 | No | ||
114 | IGFALS | 6350195 | 12215 | -0.025 | 0.1581 | No | ||
115 | SDHA | 7000056 | 12362 | -0.029 | 0.1503 | No | ||
116 | RPL27 | 1940088 | 12937 | -0.045 | 0.1194 | No | ||
117 | SUCLG1 | 1850082 5290270 | 13154 | -0.053 | 0.1079 | No | ||
118 | RPL41 | 6940112 | 13257 | -0.058 | 0.1026 | No | ||
119 | RPLP1 | 3140292 | 14086 | -0.116 | 0.0582 | No | ||
120 | CHRM3 | 6110725 | 14139 | -0.122 | 0.0559 | No | ||
121 | FFAR1 | 540112 | 14257 | -0.137 | 0.0501 | No | ||
122 | KLK3 | 1500278 | 14421 | -0.163 | 0.0420 | No | ||
123 | RPL37 | 3170494 3870750 4280494 | 14502 | -0.179 | 0.0384 | No | ||
124 | NDUFAB1 | 1980091 | 14627 | -0.205 | 0.0325 | No | ||
125 | OGDH | 3840333 6350100 | 14835 | -0.265 | 0.0224 | No | ||
126 | RPS21 | 3120673 | 14978 | -0.306 | 0.0160 | No | ||
127 | ATF4 | 730441 1740195 | 15175 | -0.374 | 0.0070 | No | ||
128 | RPS28 | 3830221 | 15197 | -0.382 | 0.0074 | No | ||
129 | RPS29 | 580324 | 15203 | -0.385 | 0.0088 | No | ||
130 | RPS20 | 1740092 | 15204 | -0.386 | 0.0104 | No | ||
131 | RPS14 | 430541 | 15297 | -0.423 | 0.0072 | No | ||
132 | RPS16 | 510722 | 15314 | -0.430 | 0.0081 | No | ||
133 | RPL8 | 20296 | 15320 | -0.432 | 0.0096 | No | ||
134 | RPLP2 | 5290020 | 15370 | -0.462 | 0.0089 | No | ||
135 | RPL39 | 2370446 | 15524 | -0.539 | 0.0029 | No | ||
136 | COX4I1 | 5340427 | 15548 | -0.548 | 0.0039 | No | ||
137 | RPL28 | 6900136 | 15833 | -0.705 | -0.0085 | No | ||
138 | MMP2 | 2570603 | 15857 | -0.723 | -0.0068 | No | ||
139 | RPL5 | 840095 | 15866 | -0.731 | -0.0041 | No | ||
140 | RPS5 | 580093 | 15972 | -0.790 | -0.0065 | No | ||
141 | ATP5B | 3870138 | 16029 | -0.841 | -0.0061 | No | ||
142 | RPL19 | 5550592 | 16041 | -0.846 | -0.0031 | No | ||
143 | RPS25 | 520139 | 16050 | -0.853 | 0.0000 | No | ||
144 | UQCRC2 | 5550091 | 16127 | -0.914 | -0.0003 | No | ||
145 | PDHA1 | 5550397 | 16299 | -1.004 | -0.0054 | No | ||
146 | NDUFC1 | 2570377 4200239 | 16500 | -1.190 | -0.0112 | No | ||
147 | PRKAR2B | 3130593 5220577 | 16564 | -1.246 | -0.0094 | No | ||
148 | NDUFA2 | 6020100 | 16675 | -1.350 | -0.0097 | No | ||
149 | SLC30A7 | 2230463 | 16722 | -1.401 | -0.0064 | No | ||
150 | ETFDH | 4670358 | 16755 | -1.441 | -0.0021 | No | ||
151 | COX6C | 1400020 | 16756 | -1.446 | 0.0039 | No | ||
152 | RPL11 | 3780435 | 16847 | -1.561 | 0.0056 | No | ||
153 | SRP14 | 5390747 | 17147 | -1.902 | -0.0027 | No | ||
154 | IQGAP1 | 6660494 | 17182 | -1.938 | 0.0036 | No | ||
155 | NDUFA4 | 6860364 | 17292 | -2.100 | 0.0064 | No | ||
156 | SEC11A | 6420563 | 17385 | -2.251 | 0.0109 | No | ||
157 | NFYA | 5860368 | 17973 | -3.463 | -0.0065 | No | ||
158 | NDUFS4 | 510142 1240148 4760253 | 18236 | -4.416 | -0.0022 | No | ||
159 | EXOC8 | 5860133 | 18402 | -5.448 | 0.0116 | No |