Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
Upregulated in class | absentNotch |
GeneSet | CELL_CYCLE_PROCESS |
Enrichment Score (ES) | -0.5188517 |
Normalized Enrichment Score (NES) | -1.5466548 |
Nominal p-value | 0.0 |
FDR q-value | 0.6900679 |
FWER p-Value | 0.997 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | BCAT1 | 3290128 4050408 | 46 | 4.735 | 0.0292 | No | ||
2 | MSH5 | 1340019 4730333 | 294 | 3.221 | 0.0373 | No | ||
3 | CDC25B | 6940102 | 346 | 3.071 | 0.0551 | No | ||
4 | CDK10 | 60164 1190717 3130128 3990044 | 676 | 2.453 | 0.0537 | No | ||
5 | CHMP1A | 5550441 | 807 | 2.253 | 0.0617 | No | ||
6 | MAD2L2 | 1240358 | 824 | 2.237 | 0.0758 | No | ||
7 | PRMT5 | 2760180 4590072 | 894 | 2.145 | 0.0864 | No | ||
8 | CDK4 | 540075 4540600 | 1065 | 1.953 | 0.0902 | No | ||
9 | POLD1 | 4830026 | 1142 | 1.881 | 0.0987 | No | ||
10 | UBE2C | 6130017 | 1159 | 1.873 | 0.1103 | No | ||
11 | DCTN2 | 540471 3780717 | 1404 | 1.640 | 0.1081 | No | ||
12 | CDKN2D | 6040035 | 1746 | 1.413 | 0.0991 | No | ||
13 | MAP3K11 | 7000039 | 1887 | 1.287 | 0.1001 | No | ||
14 | TARDBP | 870390 2350093 | 2211 | 1.070 | 0.0897 | No | ||
15 | SMC1A | 3060600 5700148 5890113 6370154 | 2340 | 1.001 | 0.0895 | No | ||
16 | NUMA1 | 6520576 | 2509 | 0.904 | 0.0864 | No | ||
17 | CHFR | 3390050 6450300 6450736 | 2514 | 0.901 | 0.0922 | No | ||
18 | BIRC5 | 110408 580014 1770632 | 3098 | 0.608 | 0.0647 | No | ||
19 | CDKN1B | 3800025 6450044 | 3383 | 0.512 | 0.0527 | No | ||
20 | DUSP13 | 6400152 | 3397 | 0.508 | 0.0554 | No | ||
21 | TGFB1 | 1940162 | 3412 | 0.500 | 0.0580 | No | ||
22 | BOLL | 6100743 | 3416 | 0.500 | 0.0612 | No | ||
23 | APBB1 | 2690338 | 3452 | 0.486 | 0.0625 | No | ||
24 | USH1C | 1570372 4230364 | 3509 | 0.468 | 0.0626 | No | ||
25 | CDKN2C | 5050750 5130148 | 3520 | 0.464 | 0.0652 | No | ||
26 | SMC3 | 870546 1400411 5700039 6450577 | 3621 | 0.436 | 0.0627 | No | ||
27 | CDCA5 | 5670131 | 3717 | 0.414 | 0.0603 | No | ||
28 | ANLN | 1780113 2470537 6840047 | 3777 | 0.399 | 0.0598 | No | ||
29 | TOP3A | 7000435 | 3933 | 0.366 | 0.0538 | No | ||
30 | CENTD2 | 60408 2510156 6100494 | 4111 | 0.332 | 0.0465 | No | ||
31 | CUL2 | 4200278 | 4463 | 0.274 | 0.0293 | No | ||
32 | XRCC2 | 4920706 | 4777 | 0.232 | 0.0139 | No | ||
33 | PAFAH1B1 | 4230333 6420121 6450066 | 4946 | 0.213 | 0.0062 | No | ||
34 | MDM4 | 4070504 4780008 | 5054 | 0.200 | 0.0017 | No | ||
35 | BUB1 | 5390270 | 5073 | 0.197 | 0.0021 | No | ||
36 | ANAPC11 | 1780601 | 5243 | 0.179 | -0.0059 | No | ||
37 | SUGT1 | 1690670 | 5398 | 0.167 | -0.0131 | No | ||
38 | GFI1B | 4570131 | 5642 | 0.149 | -0.0253 | No | ||
39 | RCC1 | 2480358 | 5687 | 0.146 | -0.0267 | No | ||
40 | PLK1 | 1780369 2640121 | 5726 | 0.143 | -0.0278 | No | ||
41 | PIN1 | 2970408 | 6011 | 0.123 | -0.0424 | No | ||
42 | TTN | 2320161 4670056 6550026 | 6492 | 0.098 | -0.0677 | No | ||
43 | KATNA1 | 6290048 | 6494 | 0.098 | -0.0671 | No | ||
44 | NBN | 730538 2470619 4780594 | 6543 | 0.095 | -0.0691 | No | ||
45 | RAD51 | 6110450 6980280 | 6595 | 0.093 | -0.0712 | No | ||
46 | TIMELESS | 3710315 | 6892 | 0.082 | -0.0867 | No | ||
47 | CETN1 | 6020056 | 6926 | 0.081 | -0.0879 | No | ||
48 | CDKN3 | 110520 | 7058 | 0.076 | -0.0945 | No | ||
49 | ANAPC10 | 870086 1170037 2260129 | 7177 | 0.072 | -0.1004 | No | ||
50 | KIF15 | 610731 4070731 6520014 | 7299 | 0.068 | -0.1065 | No | ||
51 | EREG | 50519 4920129 | 7329 | 0.067 | -0.1077 | No | ||
52 | CIT | 2370601 | 7958 | 0.051 | -0.1414 | No | ||
53 | CENPE | 2850022 | 8038 | 0.049 | -0.1453 | No | ||
54 | RAD1 | 4200551 | 8047 | 0.049 | -0.1454 | No | ||
55 | NEK2 | 2120520 | 8069 | 0.049 | -0.1462 | No | ||
56 | ATM | 3610110 4050524 | 8101 | 0.048 | -0.1476 | No | ||
57 | TPD52L1 | 4590711 5570575 | 8714 | 0.035 | -0.1805 | No | ||
58 | KIF22 | 1190368 | 8827 | 0.032 | -0.1864 | No | ||
59 | SYCP1 | 2570010 | 8861 | 0.032 | -0.1879 | No | ||
60 | RAN | 2260446 4590647 | 8979 | 0.029 | -0.1941 | No | ||
61 | NPM2 | 6040139 | 9015 | 0.028 | -0.1958 | No | ||
62 | FBXO5 | 2630551 | 10381 | 0.005 | -0.2697 | No | ||
63 | KIF11 | 5390139 | 10668 | 0.000 | -0.2852 | No | ||
64 | CCNA1 | 6290113 | 10698 | -0.000 | -0.2868 | No | ||
65 | DMC1 | 450341 | 10741 | -0.001 | -0.2890 | No | ||
66 | EPGN | 6980450 | 11154 | -0.008 | -0.3113 | No | ||
67 | TGFA | 1570332 | 11228 | -0.009 | -0.3152 | No | ||
68 | DCTN3 | 6840131 | 11249 | -0.010 | -0.3162 | No | ||
69 | CUL5 | 450142 | 11750 | -0.019 | -0.3432 | No | ||
70 | HSPA2 | 6420592 | 11784 | -0.020 | -0.3448 | No | ||
71 | MSH4 | 3940068 | 11859 | -0.021 | -0.3487 | No | ||
72 | PAM | 5290528 | 11933 | -0.023 | -0.3525 | No | ||
73 | CENPF | 5050088 | 12052 | -0.026 | -0.3587 | No | ||
74 | NPM1 | 4730427 | 12434 | -0.034 | -0.3791 | No | ||
75 | SPO11 | 540288 4780239 | 12551 | -0.038 | -0.3852 | No | ||
76 | CDC25C | 2570673 4760161 6520707 | 12613 | -0.040 | -0.3882 | No | ||
77 | CLIP1 | 2850162 6770397 | 12816 | -0.045 | -0.3989 | No | ||
78 | TTK | 3800129 | 12873 | -0.047 | -0.4016 | No | ||
79 | POLA1 | 4760541 | 13060 | -0.053 | -0.4113 | No | ||
80 | PML | 50093 2190435 2450402 3840082 | 13638 | -0.078 | -0.4420 | No | ||
81 | ACVR1 | 6840671 | 14141 | -0.115 | -0.4685 | No | ||
82 | RAD51L1 | 4010112 5860435 | 14207 | -0.122 | -0.4712 | No | ||
83 | LATS2 | 4480593 6020494 | 14232 | -0.125 | -0.4716 | No | ||
84 | APBB2 | 5130403 | 14264 | -0.129 | -0.4725 | No | ||
85 | CDKN2B | 6020040 | 14377 | -0.141 | -0.4776 | No | ||
86 | SMC4 | 5910240 | 14498 | -0.158 | -0.4830 | No | ||
87 | CDC23 | 3190593 | 14662 | -0.186 | -0.4906 | No | ||
88 | ABL1 | 1050593 2030050 4010114 | 14663 | -0.186 | -0.4894 | No | ||
89 | CHEK1 | 50167 1940300 | 14675 | -0.188 | -0.4887 | No | ||
90 | TIPIN | 1570301 2480113 | 14713 | -0.197 | -0.4894 | No | ||
91 | NEK6 | 3360687 | 14798 | -0.213 | -0.4925 | No | ||
92 | CDK6 | 4920253 | 14861 | -0.226 | -0.4944 | No | ||
93 | PIM2 | 840136 5720692 7100577 | 14884 | -0.231 | -0.4940 | No | ||
94 | CDKN1A | 4050088 6400706 | 14886 | -0.231 | -0.4925 | No | ||
95 | RAD50 | 4050184 6770746 | 14941 | -0.246 | -0.4938 | No | ||
96 | RACGAP1 | 3990162 6620736 | 15317 | -0.354 | -0.5117 | No | ||
97 | SSSCA1 | 1240402 780309 | 15332 | -0.361 | -0.5101 | No | ||
98 | RAD17 | 5220739 | 15371 | -0.377 | -0.5096 | No | ||
99 | PPP5C | 3130047 | 15422 | -0.394 | -0.5097 | No | ||
100 | TUBG1 | 3140204 | 15432 | -0.397 | -0.5075 | No | ||
101 | CCNA2 | 5290075 | 15560 | -0.440 | -0.5115 | No | ||
102 | ACVR1B | 3610446 5570195 | 15636 | -0.471 | -0.5124 | No | ||
103 | EGF | 5220154 | 15653 | -0.474 | -0.5101 | No | ||
104 | RAD51L3 | 2230609 2810286 3190008 3390053 4230168 | 15681 | -0.484 | -0.5083 | No | ||
105 | KIF2C | 6940082 | 15688 | -0.487 | -0.5054 | No | ||
106 | CDC6 | 4570296 5360600 | 15903 | -0.578 | -0.5131 | No | ||
107 | TBRG4 | 3610239 6370594 | 16010 | -0.629 | -0.5146 | Yes | ||
108 | DLG7 | 3120041 | 16026 | -0.639 | -0.5112 | Yes | ||
109 | CUL4A | 1170088 2320008 2470278 | 16109 | -0.671 | -0.5111 | Yes | ||
110 | DDX11 | 6590671 | 16110 | -0.672 | -0.5066 | Yes | ||
111 | CDK2AP1 | 2340156 | 16119 | -0.677 | -0.5026 | Yes | ||
112 | PCBP4 | 6350722 | 16142 | -0.693 | -0.4991 | Yes | ||
113 | MYH10 | 2640673 | 16190 | -0.718 | -0.4969 | Yes | ||
114 | BRCA2 | 4280372 | 16352 | -0.810 | -0.5002 | Yes | ||
115 | RAD54L | 2970041 | 16448 | -0.869 | -0.4995 | Yes | ||
116 | STAG3 | 3830112 | 16449 | -0.869 | -0.4937 | Yes | ||
117 | RAD21 | 1990278 | 16575 | -0.945 | -0.4941 | Yes | ||
118 | NDE1 | 1580242 3830097 | 16588 | -0.950 | -0.4884 | Yes | ||
119 | NDC80 | 4120465 | 16626 | -0.969 | -0.4840 | Yes | ||
120 | NOLC1 | 2350195 | 16652 | -0.983 | -0.4788 | Yes | ||
121 | CDC7 | 4060546 4850041 | 16711 | -1.007 | -0.4752 | Yes | ||
122 | AURKA | 780537 | 16736 | -1.026 | -0.4696 | Yes | ||
123 | TUBE1 | 2360079 6520685 | 16739 | -1.028 | -0.4628 | Yes | ||
124 | CDK2 | 130484 2260301 4010088 5050110 | 16838 | -1.088 | -0.4609 | Yes | ||
125 | KNTC1 | 430079 | 16852 | -1.098 | -0.4542 | Yes | ||
126 | POLS | 5890438 | 16883 | -1.130 | -0.4483 | Yes | ||
127 | E2F1 | 5360093 | 17060 | -1.284 | -0.4493 | Yes | ||
128 | GFI1 | 730180 | 17066 | -1.293 | -0.4409 | Yes | ||
129 | CDKN2A | 4670215 4760047 | 17178 | -1.404 | -0.4375 | Yes | ||
130 | CDC16 | 1940706 | 17321 | -1.556 | -0.4348 | Yes | ||
131 | PTPRC | 130402 5290148 | 17334 | -1.574 | -0.4249 | Yes | ||
132 | NUSAP1 | 940048 3120435 | 17345 | -1.583 | -0.4149 | Yes | ||
133 | CUL1 | 1990632 | 17375 | -1.620 | -0.4056 | Yes | ||
134 | ZW10 | 2900735 3520687 | 17385 | -1.639 | -0.3952 | Yes | ||
135 | STMN1 | 1990717 | 17470 | -1.733 | -0.3881 | Yes | ||
136 | BUB1B | 1450288 | 17575 | -1.842 | -0.3814 | Yes | ||
137 | CUL3 | 1850520 | 17579 | -1.848 | -0.3693 | Yes | ||
138 | CDKN1C | 6520577 | 17620 | -1.891 | -0.3588 | Yes | ||
139 | RAD52 | 110093 | 17646 | -1.925 | -0.3473 | Yes | ||
140 | MRE11A | 3850601 4670332 | 17669 | -1.971 | -0.3353 | Yes | ||
141 | ANAPC5 | 730164 7100685 | 17694 | -2.010 | -0.3231 | Yes | ||
142 | LIG3 | 2940300 | 17720 | -2.055 | -0.3108 | Yes | ||
143 | CD28 | 1400739 4210093 | 17795 | -2.145 | -0.3004 | Yes | ||
144 | KHDRBS1 | 1240403 6040040 | 17875 | -2.247 | -0.2897 | Yes | ||
145 | PPP6C | 2450670 | 17945 | -2.361 | -0.2776 | Yes | ||
146 | KIF23 | 5570112 | 17948 | -2.363 | -0.2619 | Yes | ||
147 | POLE | 6020538 | 18011 | -2.478 | -0.2487 | Yes | ||
148 | ZWINT | 6940670 | 18025 | -2.496 | -0.2328 | Yes | ||
149 | TPX2 | 6420324 | 18174 | -2.830 | -0.2218 | Yes | ||
150 | AKAP8 | 4210026 | 18180 | -2.839 | -0.2031 | Yes | ||
151 | CETN3 | 3170402 | 18192 | -2.872 | -0.1845 | Yes | ||
152 | MAD2L1 | 4480725 | 18199 | -2.886 | -0.1656 | Yes | ||
153 | RB1 | 5900338 | 18205 | -2.912 | -0.1464 | Yes | ||
154 | PRC1 | 870092 5890204 | 18210 | -2.929 | -0.1270 | Yes | ||
155 | KPNA2 | 3450114 | 18222 | -2.961 | -0.1078 | Yes | ||
156 | MPHOSPH6 | 5570164 | 18246 | -3.011 | -0.0889 | Yes | ||
157 | SKP2 | 360711 380093 4810368 | 18370 | -3.435 | -0.0726 | Yes | ||
158 | NCAPH | 6220435 | 18392 | -3.506 | -0.0503 | Yes | ||
159 | ANAPC4 | 4540338 | 18469 | -3.854 | -0.0287 | Yes | ||
160 | GSPT1 | 5420050 | 18598 | -5.469 | 0.0010 | Yes |