Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
Upregulated in class | absentNotch |
GeneSet | V$USF_01 |
Enrichment Score (ES) | -0.57777905 |
Normalized Enrichment Score (NES) | -1.7306774 |
Nominal p-value | 0.0 |
FDR q-value | 0.0057553705 |
FWER p-Value | 0.058 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PLCG2 | 5720008 | 736 | 2.352 | -0.0247 | No | ||
2 | MRPL27 | 2060131 | 766 | 2.304 | -0.0114 | No | ||
3 | CHD4 | 5420059 6130338 6380717 | 827 | 2.234 | -0.0002 | No | ||
4 | SCYL1 | 5050717 | 1112 | 1.906 | -0.0033 | No | ||
5 | HTATIP | 5360739 | 1143 | 1.881 | 0.0073 | No | ||
6 | GNAS | 630441 1850373 4050152 | 1257 | 1.771 | 0.0126 | No | ||
7 | MYST3 | 5270500 | 1396 | 1.648 | 0.0158 | No | ||
8 | BAX | 3830008 | 1523 | 1.555 | 0.0190 | No | ||
9 | EEF1B2 | 4850400 6130161 | 1533 | 1.547 | 0.0285 | No | ||
10 | TEF | 1050050 3120397 4060487 | 1555 | 1.531 | 0.0372 | No | ||
11 | ISGF3G | 3190131 7100142 | 1681 | 1.463 | 0.0399 | No | ||
12 | DHX35 | 1230440 | 1774 | 1.388 | 0.0439 | No | ||
13 | OPRS1 | 6130128 6290717 | 2359 | 0.994 | 0.0187 | No | ||
14 | ALG1 | 2570112 | 2396 | 0.973 | 0.0230 | No | ||
15 | GNB2 | 2350053 | 2517 | 0.898 | 0.0223 | No | ||
16 | TAF6L | 1850056 | 2521 | 0.895 | 0.0279 | No | ||
17 | RAB24 | 520601 4540739 | 2614 | 0.846 | 0.0284 | No | ||
18 | RBBP4 | 6650528 | 2771 | 0.764 | 0.0249 | No | ||
19 | CLN3 | 780368 | 2833 | 0.729 | 0.0263 | No | ||
20 | VPS33A | 780113 | 2917 | 0.683 | 0.0262 | No | ||
21 | ZNF318 | 5890091 6130021 | 3031 | 0.636 | 0.0242 | No | ||
22 | AKAP10 | 2630504 5910577 | 3117 | 0.603 | 0.0235 | No | ||
23 | EPC1 | 1570050 5290095 6900193 | 3372 | 0.514 | 0.0130 | No | ||
24 | EIF3S10 | 1190079 3840176 | 3518 | 0.465 | 0.0082 | No | ||
25 | TSC1 | 1850672 | 3536 | 0.461 | 0.0103 | No | ||
26 | SLC12A6 | 610278 1980035 5340671 | 3563 | 0.454 | 0.0118 | No | ||
27 | COPZ1 | 6940100 | 3620 | 0.436 | 0.0116 | No | ||
28 | NFX1 | 450504 | 3647 | 0.430 | 0.0129 | No | ||
29 | HOXB7 | 4540706 4610358 | 3662 | 0.426 | 0.0149 | No | ||
30 | SGOL1 | 1980075 5220092 6020711 | 3729 | 0.410 | 0.0140 | No | ||
31 | TESK2 | 6520524 | 4046 | 0.344 | -0.0009 | No | ||
32 | GABARAP | 1450286 | 4052 | 0.343 | 0.0010 | No | ||
33 | HMGN2 | 3140091 | 4113 | 0.332 | -0.0001 | No | ||
34 | POLR3C | 6940546 | 4162 | 0.324 | -0.0006 | No | ||
35 | NEUROD1 | 3060619 | 4212 | 0.316 | -0.0012 | No | ||
36 | RANBP1 | 430215 1090180 | 4516 | 0.266 | -0.0159 | No | ||
37 | OPRD1 | 4280138 | 4577 | 0.256 | -0.0175 | No | ||
38 | NRIP3 | 1340372 | 4705 | 0.240 | -0.0228 | No | ||
39 | MCOLN1 | 4480563 | 4889 | 0.220 | -0.0313 | No | ||
40 | ESR2 | 6220138 | 5254 | 0.179 | -0.0499 | No | ||
41 | DNMT3A | 4050068 4810717 | 5504 | 0.159 | -0.0624 | No | ||
42 | RAB3IL1 | 380685 5420176 | 5644 | 0.149 | -0.0690 | No | ||
43 | GGN | 1410528 4210082 5290170 | 5736 | 0.142 | -0.0730 | No | ||
44 | PHC3 | 4920332 | 5790 | 0.138 | -0.0750 | No | ||
45 | RNF146 | 1660735 | 6007 | 0.123 | -0.0859 | No | ||
46 | GTF2A1 | 4120138 4920524 5390110 1230397 | 6098 | 0.118 | -0.0900 | No | ||
47 | HOXB5 | 2900538 | 6179 | 0.114 | -0.0936 | No | ||
48 | MCM2 | 5050139 | 6622 | 0.092 | -0.1170 | No | ||
49 | ELAVL3 | 2850014 | 6720 | 0.088 | -0.1217 | No | ||
50 | RAD9A | 110300 1940632 3990390 6040014 | 6817 | 0.084 | -0.1263 | No | ||
51 | TOM1L2 | 4810465 | 6830 | 0.084 | -0.1264 | No | ||
52 | RGL1 | 1500097 6900450 | 6958 | 0.079 | -0.1328 | No | ||
53 | IRS4 | 430341 1190450 | 7411 | 0.064 | -0.1569 | No | ||
54 | ODC1 | 5670168 | 7414 | 0.064 | -0.1566 | No | ||
55 | FSHR | 610041 7040121 | 7451 | 0.063 | -0.1581 | No | ||
56 | GATA5 | 430465 | 7483 | 0.062 | -0.1594 | No | ||
57 | SYT3 | 6380017 | 7598 | 0.059 | -0.1652 | No | ||
58 | SEPT3 | 3830022 5290079 | 7604 | 0.059 | -0.1651 | No | ||
59 | HOXC5 | 1580017 | 7853 | 0.054 | -0.1782 | No | ||
60 | GTF2H1 | 2570746 2650148 | 8154 | 0.047 | -0.1942 | No | ||
61 | SLC26A2 | 2360278 | 8250 | 0.044 | -0.1990 | No | ||
62 | BMP4 | 380113 | 8268 | 0.044 | -0.1997 | No | ||
63 | BHLHB3 | 3450438 | 8505 | 0.039 | -0.2122 | No | ||
64 | VPS16 | 430064 3390041 6860301 | 8551 | 0.038 | -0.2144 | No | ||
65 | CPT1A | 6350093 | 8589 | 0.038 | -0.2162 | No | ||
66 | FMR1 | 5050075 | 8594 | 0.037 | -0.2161 | No | ||
67 | BDNF | 2940128 3520368 | 8647 | 0.036 | -0.2187 | No | ||
68 | SLC1A7 | 1990181 | 8849 | 0.032 | -0.2294 | No | ||
69 | DUSP7 | 2940309 | 8893 | 0.031 | -0.2316 | No | ||
70 | SLC36A1 | 5080242 | 8897 | 0.031 | -0.2315 | No | ||
71 | CGN | 5890139 6370167 6400537 | 8998 | 0.029 | -0.2368 | No | ||
72 | DVL2 | 6110162 | 9171 | 0.025 | -0.2459 | No | ||
73 | PCDHA10 | 3830725 | 9437 | 0.021 | -0.2602 | No | ||
74 | HOXD10 | 6100039 | 10161 | 0.009 | -0.2993 | No | ||
75 | HOXA11 | 6980133 | 10253 | 0.007 | -0.3042 | No | ||
76 | UTY | 5890441 | 11032 | -0.006 | -0.3463 | No | ||
77 | KIAA1715 | 1190551 | 11115 | -0.008 | -0.3507 | No | ||
78 | NDUFS1 | 2650253 | 11118 | -0.008 | -0.3508 | No | ||
79 | XPO1 | 540707 | 11124 | -0.008 | -0.3510 | No | ||
80 | ADAM10 | 3780156 | 11270 | -0.010 | -0.3588 | No | ||
81 | USP15 | 610592 3520504 | 11380 | -0.012 | -0.3647 | No | ||
82 | HOXA9 | 610494 4730040 5130601 | 11544 | -0.016 | -0.3734 | No | ||
83 | UBE2B | 4780497 | 11559 | -0.016 | -0.3740 | No | ||
84 | ARMET | 5130670 | 11642 | -0.017 | -0.3784 | No | ||
85 | HOXA1 | 1190524 5420142 | 11646 | -0.017 | -0.3784 | No | ||
86 | CUL5 | 450142 | 11750 | -0.019 | -0.3839 | No | ||
87 | PPP1R3C | 2640170 | 11817 | -0.021 | -0.3873 | No | ||
88 | AP1S2 | 780279 4280707 | 11872 | -0.022 | -0.3901 | No | ||
89 | TRIM37 | 5270091 | 12097 | -0.026 | -0.4021 | No | ||
90 | ETV1 | 70735 2940603 5080463 | 12133 | -0.027 | -0.4038 | No | ||
91 | SET | 6650286 | 12253 | -0.030 | -0.4101 | No | ||
92 | ARPC5 | 1740411 3450300 | 12360 | -0.033 | -0.4156 | No | ||
93 | NPM1 | 4730427 | 12434 | -0.034 | -0.4194 | No | ||
94 | POGK | 5290315 | 12462 | -0.035 | -0.4206 | No | ||
95 | GLA | 4610364 | 12544 | -0.038 | -0.4247 | No | ||
96 | HNRPH2 | 2630040 5720671 | 12721 | -0.042 | -0.4340 | No | ||
97 | NPTX1 | 3710736 | 12876 | -0.047 | -0.4421 | No | ||
98 | RARG | 6760136 | 13002 | -0.051 | -0.4485 | No | ||
99 | AKAP1 | 110148 1740735 2260019 7000563 | 13064 | -0.053 | -0.4515 | No | ||
100 | FOXD3 | 6550156 | 13862 | -0.092 | -0.4941 | No | ||
101 | JMJD2C | 3290341 | 13956 | -0.099 | -0.4985 | No | ||
102 | SC5DL | 6650390 | 14031 | -0.106 | -0.5018 | No | ||
103 | MTCH2 | 3780603 6620215 | 14066 | -0.109 | -0.5030 | No | ||
104 | HOXA7 | 5910152 | 14119 | -0.113 | -0.5051 | No | ||
105 | HNRPD | 4120021 | 14130 | -0.114 | -0.5049 | No | ||
106 | APEX1 | 3190519 | 14319 | -0.136 | -0.5142 | No | ||
107 | DUSP1 | 6860121 | 14399 | -0.144 | -0.5175 | No | ||
108 | SUMF1 | 730050 | 14547 | -0.166 | -0.5244 | No | ||
109 | SNX5 | 1570021 6860609 | 14550 | -0.166 | -0.5235 | No | ||
110 | FEN1 | 1770541 | 14554 | -0.166 | -0.5226 | No | ||
111 | DIRC2 | 2810494 | 14749 | -0.205 | -0.5317 | No | ||
112 | BRDT | 3940102 | 14911 | -0.238 | -0.5389 | No | ||
113 | SSR1 | 5890100 | 14958 | -0.251 | -0.5398 | No | ||
114 | EIF4E | 1580403 70133 6380215 | 15012 | -0.264 | -0.5410 | No | ||
115 | TOM1 | 940398 2190053 | 15023 | -0.267 | -0.5398 | No | ||
116 | OSGEP | 5700239 | 15063 | -0.279 | -0.5401 | No | ||
117 | SLC38A2 | 1470242 3800026 | 15153 | -0.306 | -0.5430 | No | ||
118 | PICALM | 1940280 | 15162 | -0.310 | -0.5414 | No | ||
119 | NIT1 | 1230338 3940671 | 15372 | -0.377 | -0.5503 | No | ||
120 | RPL13A | 2680519 5700142 | 15430 | -0.397 | -0.5508 | No | ||
121 | PER1 | 3290315 | 15546 | -0.433 | -0.5542 | No | ||
122 | RAI14 | 770288 1660075 | 15953 | -0.607 | -0.5723 | Yes | ||
123 | RBBP6 | 2320129 | 15969 | -0.613 | -0.5692 | Yes | ||
124 | ATIC | 4010593 6380463 | 15980 | -0.616 | -0.5657 | Yes | ||
125 | CSRP2BP | 4570717 5550333 | 15991 | -0.621 | -0.5623 | Yes | ||
126 | UBXD3 | 5050193 | 16018 | -0.634 | -0.5596 | Yes | ||
127 | SLC31A2 | 1450577 | 16053 | -0.648 | -0.5572 | Yes | ||
128 | SMYD4 | 2640403 | 16089 | -0.661 | -0.5549 | Yes | ||
129 | TNRC15 | 6760746 | 16090 | -0.662 | -0.5506 | Yes | ||
130 | ZFYVE26 | 6860152 | 16114 | -0.675 | -0.5475 | Yes | ||
131 | COMMD8 | 5890358 | 16162 | -0.707 | -0.5454 | Yes | ||
132 | GPX1 | 4150093 | 16271 | -0.768 | -0.5463 | Yes | ||
133 | HSPBAP1 | 4060022 | 16783 | -1.057 | -0.5672 | Yes | ||
134 | ATF7IP | 2690176 6770021 | 16979 | -1.212 | -0.5699 | Yes | ||
135 | TFRC | 4050551 | 17049 | -1.269 | -0.5655 | Yes | ||
136 | HOXB4 | 540131 | 17071 | -1.296 | -0.5582 | Yes | ||
137 | ATF4 | 730441 1740195 | 17104 | -1.330 | -0.5514 | Yes | ||
138 | ILF3 | 940722 3190647 6520110 | 17224 | -1.453 | -0.5484 | Yes | ||
139 | HMOX1 | 1740687 | 17236 | -1.468 | -0.5395 | Yes | ||
140 | BOK | 1170373 5860446 | 17301 | -1.535 | -0.5331 | Yes | ||
141 | PFDN2 | 4230156 | 17322 | -1.560 | -0.5241 | Yes | ||
142 | STX6 | 4850750 6770278 | 17360 | -1.604 | -0.5157 | Yes | ||
143 | MAX | 5220021 | 17406 | -1.661 | -0.5074 | Yes | ||
144 | SIRT1 | 1190731 | 17426 | -1.676 | -0.4976 | Yes | ||
145 | NUDC | 4780025 | 17469 | -1.732 | -0.4887 | Yes | ||
146 | STMN1 | 1990717 | 17470 | -1.733 | -0.4775 | Yes | ||
147 | UTX | 2900017 6770452 | 17486 | -1.741 | -0.4671 | Yes | ||
148 | ZCCHC7 | 6510592 | 17506 | -1.769 | -0.4567 | Yes | ||
149 | PRPS1 | 6350129 | 17567 | -1.834 | -0.4480 | Yes | ||
150 | ALDH6A1 | 1770746 | 17581 | -1.852 | -0.4368 | Yes | ||
151 | CCAR1 | 3190092 | 17750 | -2.089 | -0.4324 | Yes | ||
152 | AKAP12 | 1450739 | 17771 | -2.116 | -0.4198 | Yes | ||
153 | EIF4B | 5390563 5270577 | 17772 | -2.116 | -0.4061 | Yes | ||
154 | TIMM8A | 110279 | 17789 | -2.135 | -0.3932 | Yes | ||
155 | LAMP1 | 2470524 | 17867 | -2.240 | -0.3829 | Yes | ||
156 | PPM1A | 1170301 5900273 | 17938 | -2.352 | -0.3714 | Yes | ||
157 | ATP6V1A | 6590242 | 17950 | -2.364 | -0.3568 | Yes | ||
158 | U2AF2 | 450600 4670128 5420292 | 17972 | -2.405 | -0.3423 | Yes | ||
159 | COMMD3 | 2510259 | 17990 | -2.440 | -0.3275 | Yes | ||
160 | HTF9C | 3190048 4120132 | 18033 | -2.513 | -0.3135 | Yes | ||
161 | MORF4L2 | 6450133 | 18050 | -2.548 | -0.2979 | Yes | ||
162 | IGF2R | 1570402 | 18072 | -2.593 | -0.2823 | Yes | ||
163 | AATF | 5220575 | 18074 | -2.600 | -0.2655 | Yes | ||
164 | GSK3B | 5360348 | 18106 | -2.696 | -0.2498 | Yes | ||
165 | EIF4G1 | 4070446 | 18120 | -2.717 | -0.2329 | Yes | ||
166 | DDX3X | 2190020 | 18122 | -2.725 | -0.2154 | Yes | ||
167 | RPA1 | 360452 | 18150 | -2.775 | -0.1989 | Yes | ||
168 | BRD2 | 1450300 5340484 6100605 | 18220 | -2.955 | -0.1835 | Yes | ||
169 | HPS3 | 6650348 | 18274 | -3.080 | -0.1665 | Yes | ||
170 | GNA13 | 4590102 | 18371 | -3.438 | -0.1495 | Yes | ||
171 | TOPORS | 4060592 | 18389 | -3.500 | -0.1278 | Yes | ||
172 | KBTBD2 | 2320014 | 18404 | -3.580 | -0.1054 | Yes | ||
173 | DCTN4 | 3390010 5550170 | 18420 | -3.620 | -0.0828 | Yes | ||
174 | PTMA | 5570148 | 18446 | -3.752 | -0.0599 | Yes | ||
175 | CD164 | 3830594 | 18548 | -4.479 | -0.0364 | Yes | ||
176 | UBE4B | 780008 3610154 | 18612 | -6.192 | 0.0002 | Yes |