Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
Upregulated in class | truncNotch |
GeneSet | V$TEF1_Q6 |
Enrichment Score (ES) | 0.4430448 |
Normalized Enrichment Score (NES) | 1.2656791 |
Nominal p-value | 0.03284072 |
FDR q-value | 0.9102275 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | MAPKAPK2 | 2850500 | 7 | 6.376 | 0.0547 | Yes | ||
2 | POLD4 | 2320082 | 63 | 4.501 | 0.0906 | Yes | ||
3 | CD2 | 430672 | 120 | 3.932 | 0.1216 | Yes | ||
4 | FRAG1 | 1050504 1170152 2030092 | 146 | 3.789 | 0.1529 | Yes | ||
5 | USP5 | 4850017 | 151 | 3.756 | 0.1852 | Yes | ||
6 | PTPRF | 1770528 3190044 | 297 | 3.211 | 0.2051 | Yes | ||
7 | BCL9L | 6940053 | 298 | 3.207 | 0.2328 | Yes | ||
8 | RASGRP2 | 2970333 | 363 | 3.026 | 0.2555 | Yes | ||
9 | LMNA | 520471 1500075 3190167 4210020 | 594 | 2.565 | 0.2652 | Yes | ||
10 | NFKB2 | 2320670 | 763 | 2.310 | 0.2760 | Yes | ||
11 | CHD4 | 5420059 6130338 6380717 | 827 | 2.234 | 0.2919 | Yes | ||
12 | DEDD | 6400131 | 845 | 2.203 | 0.3100 | Yes | ||
13 | PTPRCAP | 6650075 | 916 | 2.109 | 0.3244 | Yes | ||
14 | IPO13 | 3870088 | 959 | 2.058 | 0.3399 | Yes | ||
15 | AVPI1 | 1850377 | 983 | 2.039 | 0.3563 | Yes | ||
16 | EHD1 | 3840731 | 1004 | 2.017 | 0.3727 | Yes | ||
17 | SH3BGRL3 | 1850750 | 1154 | 1.875 | 0.3808 | Yes | ||
18 | RBM14 | 5340731 5690315 | 1352 | 1.692 | 0.3848 | Yes | ||
19 | DPM3 | 50039 | 1401 | 1.643 | 0.3963 | Yes | ||
20 | CRYAB | 4810619 | 1577 | 1.517 | 0.4000 | Yes | ||
21 | SIPA1 | 5220687 | 1613 | 1.500 | 0.4110 | Yes | ||
22 | PBXIP1 | 70131 | 1712 | 1.442 | 0.4182 | Yes | ||
23 | ADD3 | 4150739 5390600 | 1745 | 1.415 | 0.4287 | Yes | ||
24 | HSPB2 | 1990110 | 1837 | 1.322 | 0.4352 | Yes | ||
25 | CNNM2 | 2650100 | 2162 | 1.096 | 0.4271 | Yes | ||
26 | EPHB2 | 1090288 1410377 2100541 | 2246 | 1.047 | 0.4317 | Yes | ||
27 | BRMS1 | 6860280 | 2413 | 0.964 | 0.4310 | Yes | ||
28 | PIAS3 | 50204 240739 4060524 | 2474 | 0.924 | 0.4357 | Yes | ||
29 | PAX2 | 6040270 7000133 | 2486 | 0.916 | 0.4430 | Yes | ||
30 | PADI2 | 2940092 6420136 | 3101 | 0.607 | 0.4150 | No | ||
31 | PAQR6 | 580450 2630093 5550341 | 3159 | 0.589 | 0.4170 | No | ||
32 | EPC1 | 1570050 5290095 6900193 | 3372 | 0.514 | 0.4100 | No | ||
33 | MUC1 | 2470273 3140082 6220131 7040066 | 3458 | 0.485 | 0.4096 | No | ||
34 | SRRM1 | 6110025 | 3498 | 0.469 | 0.4115 | No | ||
35 | SWAP70 | 2810577 2850739 5130594 | 3516 | 0.466 | 0.4146 | No | ||
36 | CDKN2C | 5050750 5130148 | 3520 | 0.464 | 0.4185 | No | ||
37 | RAPSN | 610110 2370162 | 3534 | 0.461 | 0.4218 | No | ||
38 | EPHA2 | 5890056 | 3762 | 0.403 | 0.4130 | No | ||
39 | PVRL1 | 2570167 5220519 5890500 3190309 | 3838 | 0.388 | 0.4122 | No | ||
40 | SLC6A9 | 2470520 | 3974 | 0.358 | 0.4080 | No | ||
41 | MRGPRF | 4780746 | 4064 | 0.341 | 0.4062 | No | ||
42 | HMGN2 | 3140091 | 4113 | 0.332 | 0.4064 | No | ||
43 | VAX1 | 6660750 | 4252 | 0.310 | 0.4016 | No | ||
44 | SYNPO2L | 5390719 | 4256 | 0.308 | 0.4041 | No | ||
45 | CUL2 | 4200278 | 4463 | 0.274 | 0.3953 | No | ||
46 | PRKCDBP | 4210341 | 4517 | 0.266 | 0.3948 | No | ||
47 | ELF3 | 770551 6180019 | 4583 | 0.256 | 0.3935 | No | ||
48 | TNKS1BP1 | 7040184 | 4620 | 0.250 | 0.3937 | No | ||
49 | SYTL2 | 580097 5390576 6770603 | 4856 | 0.224 | 0.3829 | No | ||
50 | TMPRSS4 | 1050402 1710128 2480341 | 4961 | 0.210 | 0.3791 | No | ||
51 | CYP26A1 | 380022 2690600 | 5361 | 0.170 | 0.3589 | No | ||
52 | ST5 | 3780204 | 5607 | 0.152 | 0.3470 | No | ||
53 | JAM3 | 4280193 | 5768 | 0.139 | 0.3395 | No | ||
54 | CYR61 | 1240408 5290026 4120452 6550008 | 5791 | 0.138 | 0.3395 | No | ||
55 | KIF1B | 1240494 2370139 4570270 6510102 | 5966 | 0.126 | 0.3312 | No | ||
56 | SLC17A6 | 4210576 | 6026 | 0.122 | 0.3290 | No | ||
57 | NNMT | 450471 | 6203 | 0.113 | 0.3205 | No | ||
58 | CACNA1E | 840253 | 6355 | 0.104 | 0.3132 | No | ||
59 | LMOD1 | 2120035 | 6507 | 0.097 | 0.3059 | No | ||
60 | CACNA1S | 4730465 | 6509 | 0.097 | 0.3067 | No | ||
61 | ANKRD1 | 4850685 | 6714 | 0.089 | 0.2964 | No | ||
62 | TNNI3K | 5890072 | 6755 | 0.087 | 0.2950 | No | ||
63 | NES | 1190672 2450167 | 6849 | 0.083 | 0.2906 | No | ||
64 | FOLR1 | 2470369 | 6986 | 0.078 | 0.2839 | No | ||
65 | JMJD1C | 940575 2120025 | 7022 | 0.077 | 0.2827 | No | ||
66 | ETV3 | 5360487 | 7062 | 0.076 | 0.2813 | No | ||
67 | TNRC4 | 4050156 | 7083 | 0.075 | 0.2808 | No | ||
68 | TNNT2 | 2450364 | 7148 | 0.073 | 0.2780 | No | ||
69 | THBS3 | 2360465 4050176 | 7254 | 0.070 | 0.2729 | No | ||
70 | SYT8 | 4280551 | 7260 | 0.070 | 0.2732 | No | ||
71 | ACTA1 | 840538 | 7533 | 0.061 | 0.2590 | No | ||
72 | DAB1 | 2060193 7000605 | 7830 | 0.054 | 0.2435 | No | ||
73 | EIF2C1 | 6900551 | 8005 | 0.050 | 0.2345 | No | ||
74 | RTN4RL2 | 6450609 | 8212 | 0.045 | 0.2237 | No | ||
75 | BBOX1 | 2030538 2370452 | 8463 | 0.040 | 0.2105 | No | ||
76 | ANXA8 | 4780022 | 8572 | 0.038 | 0.2050 | No | ||
77 | CPT1A | 6350093 | 8589 | 0.038 | 0.2045 | No | ||
78 | BDNF | 2940128 3520368 | 8647 | 0.036 | 0.2017 | No | ||
79 | TIAL1 | 4150048 6510605 | 8663 | 0.036 | 0.2012 | No | ||
80 | POGZ | 870348 7040286 | 8779 | 0.033 | 0.1953 | No | ||
81 | SLC1A7 | 1990181 | 8849 | 0.032 | 0.1918 | No | ||
82 | CGN | 5890139 6370167 6400537 | 8998 | 0.029 | 0.1840 | No | ||
83 | ATPAF1 | 2470164 | 9044 | 0.028 | 0.1818 | No | ||
84 | PRRX1 | 4120193 4480390 | 9053 | 0.028 | 0.1816 | No | ||
85 | MFAP5 | 4920139 | 9168 | 0.025 | 0.1757 | No | ||
86 | RNF2 | 2340497 | 9196 | 0.025 | 0.1744 | No | ||
87 | VANGL1 | 380162 | 9426 | 0.021 | 0.1622 | No | ||
88 | PTPRJ | 4010707 | 9555 | 0.019 | 0.1554 | No | ||
89 | SYT2 | 60609 | 9843 | 0.014 | 0.1400 | No | ||
90 | RAB18 | 3120575 4590577 | 10497 | 0.003 | 0.1047 | No | ||
91 | KIRREL3 | 2630195 | 10727 | -0.001 | 0.0923 | No | ||
92 | TLX1 | 2630162 | 11225 | -0.009 | 0.0655 | No | ||
93 | PBX1 | 6660301 | 11368 | -0.012 | 0.0579 | No | ||
94 | IER5 | 2350575 | 11920 | -0.023 | 0.0282 | No | ||
95 | LAMB3 | 7100301 | 11925 | -0.023 | 0.0282 | No | ||
96 | DNM3 | 730711 | 11983 | -0.024 | 0.0253 | No | ||
97 | MPZ | 1990333 | 12034 | -0.025 | 0.0229 | No | ||
98 | PRDM16 | 4120541 | 12191 | -0.029 | 0.0147 | No | ||
99 | DR1 | 5860750 | 12291 | -0.031 | 0.0096 | No | ||
100 | SDCCAG8 | 1780687 | 12446 | -0.035 | 0.0015 | No | ||
101 | POGK | 5290315 | 12462 | -0.035 | 0.0010 | No | ||
102 | OVOL1 | 1690131 | 12538 | -0.037 | -0.0027 | No | ||
103 | LHX4 | 6940551 | 12675 | -0.041 | -0.0097 | No | ||
104 | LOXL4 | 6520095 | 12841 | -0.046 | -0.0183 | No | ||
105 | HOOK1 | 840450 940390 2480500 2690402 | 13046 | -0.053 | -0.0289 | No | ||
106 | LIN28 | 6590672 | 13101 | -0.054 | -0.0313 | No | ||
107 | KCNIP2 | 60088 1780324 | 13132 | -0.055 | -0.0325 | No | ||
108 | EPS8L2 | 2850528 | 13151 | -0.056 | -0.0330 | No | ||
109 | NOTCH2 | 2570397 | 13205 | -0.058 | -0.0353 | No | ||
110 | SCNN1A | 4730019 | 13341 | -0.064 | -0.0421 | No | ||
111 | NPPB | 4150722 | 13455 | -0.068 | -0.0476 | No | ||
112 | WNT3A | 6350348 | 13906 | -0.096 | -0.0712 | No | ||
113 | LAMC2 | 450692 2680041 4200059 4670148 | 13987 | -0.102 | -0.0746 | No | ||
114 | KISS1 | 1580398 | 14159 | -0.117 | -0.0829 | No | ||
115 | USP2 | 1190292 1240253 4850035 | 14344 | -0.138 | -0.0916 | No | ||
116 | OLFML3 | 7100463 | 14657 | -0.186 | -0.1069 | No | ||
117 | MDK | 3840020 | 14706 | -0.196 | -0.1078 | No | ||
118 | ABCG4 | 3440458 | 14896 | -0.235 | -0.1160 | No | ||
119 | FGFR2 | 4670601 5570402 6940377 | 15016 | -0.265 | -0.1202 | No | ||
120 | PEA15 | 4590685 | 15176 | -0.313 | -0.1261 | No | ||
121 | HDGF | 5130114 5420066 6590152 | 15190 | -0.318 | -0.1240 | No | ||
122 | ELAVL4 | 50735 3360086 5220167 | 15306 | -0.352 | -0.1272 | No | ||
123 | SHC1 | 2900731 3170504 6520537 | 15440 | -0.398 | -0.1310 | No | ||
124 | TIMM23 | 60288 7040133 | 15514 | -0.425 | -0.1313 | No | ||
125 | MTX1 | 5910059 6550181 | 15544 | -0.432 | -0.1291 | No | ||
126 | OVGP1 | 2630746 2940372 | 15579 | -0.448 | -0.1271 | No | ||
127 | EGR2 | 3800403 | 15588 | -0.452 | -0.1236 | No | ||
128 | CHKA | 510324 | 15685 | -0.486 | -0.1246 | No | ||
129 | MAST2 | 6200348 | 15711 | -0.496 | -0.1217 | No | ||
130 | MADD | 6100725 7000088 | 15877 | -0.566 | -0.1257 | No | ||
131 | UBXD3 | 5050193 | 16018 | -0.634 | -0.1278 | No | ||
132 | MCAM | 5130270 6620577 | 16019 | -0.635 | -0.1223 | No | ||
133 | ANK3 | 1500161 2900435 4210154 6400100 | 16147 | -0.695 | -0.1232 | No | ||
134 | CDC14A | 4050132 | 16473 | -0.881 | -0.1332 | No | ||
135 | LAMC1 | 4730025 | 16521 | -0.908 | -0.1279 | No | ||
136 | IFRG15 | 2810538 | 16613 | -0.963 | -0.1245 | No | ||
137 | MAN1A2 | 5700435 5720114 | 16623 | -0.967 | -0.1166 | No | ||
138 | GATA3 | 6130068 | 16668 | -0.991 | -0.1104 | No | ||
139 | CCND2 | 5340167 | 17008 | -1.231 | -0.1182 | No | ||
140 | FXYD6 | 3870164 | 17054 | -1.278 | -0.1096 | No | ||
141 | IL18BP | 3450128 | 17117 | -1.342 | -0.1013 | No | ||
142 | CDCA3 | 3940397 | 17166 | -1.392 | -0.0919 | No | ||
143 | ADIPOR1 | 3140440 | 17414 | -1.664 | -0.0909 | No | ||
144 | VCL | 4120487 | 17715 | -2.044 | -0.0895 | No | ||
145 | ARID1A | 2630022 1690551 4810110 | 17864 | -2.236 | -0.0782 | No | ||
146 | CNN3 | 6110020 | 17930 | -2.342 | -0.0614 | No | ||
147 | SLC6A13 | 5270152 | 18052 | -2.549 | -0.0460 | No | ||
148 | PPFIA1 | 430176 3610524 | 18105 | -2.694 | -0.0255 | No | ||
149 | ATP1B1 | 3130594 | 18138 | -2.762 | -0.0034 | No | ||
150 | ITGB1 | 5080156 6270528 | 18356 | -3.381 | 0.0141 | No |