Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
Upregulated in class | truncNotch |
GeneSet | V$PEA3_Q6 |
Enrichment Score (ES) | 0.4528966 |
Normalized Enrichment Score (NES) | 1.3000811 |
Nominal p-value | 0.031879194 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | MAPKAPK2 | 2850500 | 7 | 6.376 | 0.0370 | Yes | ||
2 | IL2RA | 6620450 | 8 | 6.074 | 0.0727 | Yes | ||
3 | CD5 | 6590338 | 9 | 6.037 | 0.1081 | Yes | ||
4 | RHOG | 6760575 | 27 | 5.267 | 0.1381 | Yes | ||
5 | LPXN | 2360142 | 37 | 4.933 | 0.1665 | Yes | ||
6 | POLD4 | 2320082 | 63 | 4.501 | 0.1916 | Yes | ||
7 | TCIRG1 | 4590524 5910079 6900619 | 130 | 3.880 | 0.2107 | Yes | ||
8 | POU2AF1 | 5690242 | 230 | 3.410 | 0.2254 | Yes | ||
9 | ELOVL1 | 2450019 4760138 5340685 | 268 | 3.294 | 0.2427 | Yes | ||
10 | PTPN6 | 4230128 | 340 | 3.085 | 0.2570 | Yes | ||
11 | PIK4CB | 510450 1780452 | 418 | 2.874 | 0.2696 | Yes | ||
12 | ZNF289 | 3610390 3870711 3940138 5340373 | 485 | 2.746 | 0.2822 | Yes | ||
13 | RPS6KA4 | 2190524 | 536 | 2.652 | 0.2950 | Yes | ||
14 | TYSND1 | 2940273 | 648 | 2.496 | 0.3037 | Yes | ||
15 | ADRBK1 | 1340333 | 668 | 2.469 | 0.3171 | Yes | ||
16 | SLC2A3 | 1990377 | 686 | 2.432 | 0.3305 | Yes | ||
17 | CTSW | 360368 | 823 | 2.238 | 0.3362 | Yes | ||
18 | SELL | 1190500 | 841 | 2.211 | 0.3483 | Yes | ||
19 | PRF1 | 6660309 | 863 | 2.187 | 0.3600 | Yes | ||
20 | DGKZ | 3460041 6400129 | 927 | 2.098 | 0.3688 | Yes | ||
21 | TNNI2 | 5910739 | 1180 | 1.850 | 0.3660 | Yes | ||
22 | MAP4K2 | 4200037 | 1189 | 1.841 | 0.3764 | Yes | ||
23 | ARHGDIB | 4730433 | 1251 | 1.773 | 0.3835 | Yes | ||
24 | SLAMF9 | 3710300 | 1509 | 1.564 | 0.3788 | Yes | ||
25 | ESRRA | 6550242 | 1556 | 1.530 | 0.3852 | Yes | ||
26 | LCK | 3360142 | 1591 | 1.510 | 0.3923 | Yes | ||
27 | SSBP3 | 870717 1050377 7040551 | 1603 | 1.506 | 0.4005 | Yes | ||
28 | UNC93B1 | 430152 | 1605 | 1.505 | 0.4093 | Yes | ||
29 | SIPA1 | 5220687 | 1613 | 1.500 | 0.4177 | Yes | ||
30 | SLC35C1 | 4540154 | 1683 | 1.462 | 0.4225 | Yes | ||
31 | PBXIP1 | 70131 | 1712 | 1.442 | 0.4295 | Yes | ||
32 | SELP | 6040193 | 1757 | 1.406 | 0.4353 | Yes | ||
33 | SYTL1 | 510487 | 1933 | 1.252 | 0.4332 | Yes | ||
34 | DPP3 | 2680725 3780670 | 1971 | 1.228 | 0.4384 | Yes | ||
35 | CD3E | 3800056 | 2032 | 1.180 | 0.4421 | Yes | ||
36 | SPI1 | 1410397 | 2208 | 1.071 | 0.4389 | Yes | ||
37 | KCNAB2 | 4850315 | 2276 | 1.032 | 0.4413 | Yes | ||
38 | MFN2 | 2260195 6100164 | 2339 | 1.001 | 0.4438 | Yes | ||
39 | KCNQ1 | 1580050 6860441 | 2448 | 0.942 | 0.4435 | Yes | ||
40 | BLNK | 70288 6590092 | 2451 | 0.941 | 0.4489 | Yes | ||
41 | NUMA1 | 6520576 | 2509 | 0.904 | 0.4511 | Yes | ||
42 | ZRANB1 | 510373 4540278 | 2571 | 0.867 | 0.4529 | Yes | ||
43 | LAG3 | 6860112 | 2778 | 0.761 | 0.4462 | No | ||
44 | TMEM24 | 5860039 | 2797 | 0.746 | 0.4496 | No | ||
45 | RUNX3 | 3800546 | 2847 | 0.719 | 0.4512 | No | ||
46 | BCL2L14 | 2940279 | 3033 | 0.636 | 0.4449 | No | ||
47 | CD53 | 5550162 | 3096 | 0.609 | 0.4451 | No | ||
48 | CAP1 | 2650278 | 3127 | 0.600 | 0.4470 | No | ||
49 | CAMK1D | 1660100 2350309 | 3247 | 0.557 | 0.4438 | No | ||
50 | EPC1 | 1570050 5290095 6900193 | 3372 | 0.514 | 0.4401 | No | ||
51 | SRRM1 | 6110025 | 3498 | 0.469 | 0.4361 | No | ||
52 | PLCB3 | 4670402 | 3504 | 0.469 | 0.4386 | No | ||
53 | CDKN2C | 5050750 5130148 | 3520 | 0.464 | 0.4405 | No | ||
54 | EPHA2 | 5890056 | 3762 | 0.403 | 0.4298 | No | ||
55 | MMRN2 | 1740047 | 3843 | 0.386 | 0.4277 | No | ||
56 | NDUFS2 | 4850020 6200402 | 4091 | 0.335 | 0.4163 | No | ||
57 | CENTD2 | 60408 2510156 6100494 | 4111 | 0.332 | 0.4172 | No | ||
58 | SLC26A9 | 3440722 5340088 7510093 | 4156 | 0.324 | 0.4167 | No | ||
59 | NRGN | 4280433 | 4316 | 0.297 | 0.4099 | No | ||
60 | DMBT1 | 7050270 | 4446 | 0.276 | 0.4045 | No | ||
61 | TAF5 | 3450288 5890193 6860435 | 4591 | 0.254 | 0.3982 | No | ||
62 | LTBR | 2450341 | 4983 | 0.209 | 0.3782 | No | ||
63 | GPR120 | 2350398 | 5157 | 0.187 | 0.3699 | No | ||
64 | ST7L | 840735 2360576 | 5283 | 0.176 | 0.3642 | No | ||
65 | PRDX6 | 4920397 6380601 | 5346 | 0.171 | 0.3619 | No | ||
66 | ADAMTS4 | 430435 | 5542 | 0.156 | 0.3522 | No | ||
67 | GPD1 | 2480095 | 5576 | 0.154 | 0.3513 | No | ||
68 | FGF23 | 510746 | 5643 | 0.149 | 0.3486 | No | ||
69 | CYR61 | 1240408 5290026 4120452 6550008 | 5791 | 0.138 | 0.3415 | No | ||
70 | RAB39 | 430524 | 5792 | 0.138 | 0.3423 | No | ||
71 | FUCA1 | 610075 | 5894 | 0.131 | 0.3376 | No | ||
72 | ARF3 | 3710446 | 5939 | 0.128 | 0.3359 | No | ||
73 | CACNA1E | 840253 | 6355 | 0.104 | 0.3141 | No | ||
74 | MMP7 | 1780497 | 6700 | 0.089 | 0.2959 | No | ||
75 | ANKRD1 | 4850685 | 6714 | 0.089 | 0.2958 | No | ||
76 | ETV3 | 5360487 | 7062 | 0.076 | 0.2774 | No | ||
77 | CUGBP1 | 450292 510022 7050176 7050215 | 7149 | 0.073 | 0.2732 | No | ||
78 | SV2A | 1450039 5570685 | 7312 | 0.068 | 0.2648 | No | ||
79 | ITPKB | 2900195 7100039 | 7485 | 0.062 | 0.2558 | No | ||
80 | NCF2 | 540129 2370441 2650133 | 7517 | 0.061 | 0.2545 | No | ||
81 | IPO7 | 2190746 | 7698 | 0.057 | 0.2451 | No | ||
82 | SNCG | 3120725 | 8070 | 0.049 | 0.2253 | No | ||
83 | GTF2H1 | 2570746 2650148 | 8154 | 0.047 | 0.2211 | No | ||
84 | KAZALD1 | 380603 | 8487 | 0.040 | 0.2033 | No | ||
85 | BDNF | 2940128 3520368 | 8647 | 0.036 | 0.1949 | No | ||
86 | TIAL1 | 4150048 6510605 | 8663 | 0.036 | 0.1943 | No | ||
87 | PGM2L1 | 2350035 | 8707 | 0.035 | 0.1922 | No | ||
88 | PAX6 | 1190025 | 8766 | 0.033 | 0.1892 | No | ||
89 | GAB2 | 1410280 2340520 4280040 | 8801 | 0.033 | 0.1876 | No | ||
90 | EHF | 4560088 | 9070 | 0.027 | 0.1732 | No | ||
91 | LALBA | 6940685 | 9170 | 0.025 | 0.1680 | No | ||
92 | CPNE8 | 7040039 | 9374 | 0.022 | 0.1571 | No | ||
93 | RNASEL | 2340133 | 9755 | 0.015 | 0.1366 | No | ||
94 | GPA33 | 2650044 | 9948 | 0.012 | 0.1263 | No | ||
95 | SPRR4 | 5720273 | 11346 | -0.011 | 0.0507 | No | ||
96 | XPNPEP1 | 2640750 3850315 6200242 | 11412 | -0.013 | 0.0473 | No | ||
97 | CAPZA1 | 3140390 | 11961 | -0.024 | 0.0177 | No | ||
98 | GRIN2B | 3800333 | 12313 | -0.032 | -0.0011 | No | ||
99 | ELK4 | 460494 940369 4480136 | 12315 | -0.032 | -0.0010 | No | ||
100 | IRAK4 | 5390156 6130594 | 12923 | -0.049 | -0.0336 | No | ||
101 | LIN28 | 6590672 | 13101 | -0.054 | -0.0429 | No | ||
102 | VPS11 | 1090048 6040372 | 13155 | -0.056 | -0.0454 | No | ||
103 | IVL | 4560500 | 13187 | -0.057 | -0.0468 | No | ||
104 | FUT11 | 6040692 | 13773 | -0.086 | -0.0779 | No | ||
105 | AKT3 | 1580270 3290278 | 13982 | -0.102 | -0.0886 | No | ||
106 | MARK1 | 450484 | 14055 | -0.108 | -0.0919 | No | ||
107 | WASF2 | 4850592 | 14136 | -0.115 | -0.0955 | No | ||
108 | LRFN4 | 5670368 | 14152 | -0.116 | -0.0957 | No | ||
109 | ABLIM1 | 580170 3710338 6520504 | 14156 | -0.117 | -0.0951 | No | ||
110 | PDGFD | 60438 | 14200 | -0.121 | -0.0968 | No | ||
111 | XCL1 | 3800504 | 14211 | -0.122 | -0.0966 | No | ||
112 | PAFAH2 | 3140451 5720593 6510014 | 14368 | -0.141 | -0.1042 | No | ||
113 | FEN1 | 1770541 | 14554 | -0.166 | -0.1133 | No | ||
114 | RPS3 | 1570017 2370170 | 14773 | -0.209 | -0.1238 | No | ||
115 | SLC41A1 | 1230528 | 14961 | -0.251 | -0.1325 | No | ||
116 | IL18 | 6180039 | 15070 | -0.281 | -0.1367 | No | ||
117 | PICALM | 1940280 | 15162 | -0.310 | -0.1398 | No | ||
118 | ELAVL4 | 50735 3360086 5220167 | 15306 | -0.352 | -0.1455 | No | ||
119 | NCAM1 | 3140026 | 15416 | -0.391 | -0.1491 | No | ||
120 | CD69 | 380167 4730088 | 15476 | -0.411 | -0.1499 | No | ||
121 | MARK2 | 7210608 | 15510 | -0.424 | -0.1492 | No | ||
122 | ITPR2 | 5360128 | 15567 | -0.445 | -0.1496 | No | ||
123 | CTBP2 | 430309 3710079 | 15569 | -0.445 | -0.1471 | No | ||
124 | LZTS2 | 2260440 | 15638 | -0.471 | -0.1480 | No | ||
125 | RIN1 | 510593 | 15763 | -0.520 | -0.1516 | No | ||
126 | SORL1 | 630204 | 15778 | -0.526 | -0.1493 | No | ||
127 | TRIM33 | 580619 2230280 3990433 6200747 | 16084 | -0.659 | -0.1620 | No | ||
128 | CMAS | 2190129 | 16136 | -0.688 | -0.1607 | No | ||
129 | ANK3 | 1500161 2900435 4210154 6400100 | 16147 | -0.695 | -0.1572 | No | ||
130 | HHEX | 2340575 | 16159 | -0.703 | -0.1536 | No | ||
131 | SLC30A7 | 2230463 | 16218 | -0.745 | -0.1524 | No | ||
132 | SEC24C | 6980707 | 16262 | -0.763 | -0.1503 | No | ||
133 | HIPK1 | 110193 | 16303 | -0.786 | -0.1478 | No | ||
134 | DCLRE1C | 1450041 2360091 3290671 3390739 | 16413 | -0.844 | -0.1488 | No | ||
135 | CDC14A | 4050132 | 16473 | -0.881 | -0.1468 | No | ||
136 | INPPL1 | 110717 3120164 | 16497 | -0.893 | -0.1428 | No | ||
137 | LAMC1 | 4730025 | 16521 | -0.908 | -0.1387 | No | ||
138 | GATA3 | 6130068 | 16668 | -0.991 | -0.1408 | No | ||
139 | CTSS | 1740056 | 16721 | -1.016 | -0.1377 | No | ||
140 | NT5C2 | 4280735 4670528 | 16909 | -1.148 | -0.1411 | No | ||
141 | TNFRSF19L | 1170168 1190358 5670270 | 16939 | -1.165 | -0.1358 | No | ||
142 | FCGR3A | 3840184 | 16958 | -1.178 | -0.1299 | No | ||
143 | PUM1 | 6130500 | 16962 | -1.182 | -0.1231 | No | ||
144 | GFI1 | 730180 | 17066 | -1.293 | -0.1211 | No | ||
145 | IL18BP | 3450128 | 17117 | -1.342 | -0.1160 | No | ||
146 | VDAC2 | 7000215 | 17152 | -1.378 | -0.1097 | No | ||
147 | FLI1 | 3990142 | 17193 | -1.419 | -0.1036 | No | ||
148 | PTPRC | 130402 5290148 | 17334 | -1.574 | -0.1019 | No | ||
149 | LRMP | 6290193 | 17439 | -1.692 | -0.0976 | No | ||
150 | SPATA6 | 4590373 | 17490 | -1.749 | -0.0901 | No | ||
151 | CBL | 6380068 | 17537 | -1.799 | -0.0820 | No | ||
152 | ZDHHC5 | 1690711 | 17740 | -2.080 | -0.0807 | No | ||
153 | VCAM1 | 2900450 | 17830 | -2.190 | -0.0727 | No | ||
154 | MR1 | 3850037 | 17924 | -2.331 | -0.0641 | No | ||
155 | TCEB3 | 5890156 | 17927 | -2.336 | -0.0505 | No | ||
156 | EXTL2 | 5050433 | 18131 | -2.735 | -0.0454 | No | ||
157 | TRIM8 | 6130441 | 18163 | -2.806 | -0.0307 | No | ||
158 | CD84 | 1780168 | 18343 | -3.329 | -0.0208 | No | ||
159 | PRKACB | 4210170 | 18607 | -6.062 | 0.0005 | No |