Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
Upregulated in class | absentNotch |
GeneSet | V$E2F_Q4 |
Enrichment Score (ES) | -0.6003529 |
Normalized Enrichment Score (NES) | -1.7972273 |
Nominal p-value | 0.0 |
FDR q-value | 0.0031416572 |
FWER p-Value | 0.021 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | HIST1H2BK | 6130433 | 400 | 2.931 | -0.0030 | No | ||
2 | MXD3 | 6220014 | 879 | 2.166 | -0.0151 | No | ||
3 | UNG | 3130110 6100364 | 931 | 2.088 | -0.0046 | No | ||
4 | MAZ | 3360121 6940750 | 973 | 2.048 | 0.0062 | No | ||
5 | POLD1 | 4830026 | 1142 | 1.881 | 0.0090 | No | ||
6 | ACBD6 | 4200446 | 1685 | 1.462 | -0.0110 | No | ||
7 | SYNGR4 | 6520450 | 1888 | 1.286 | -0.0138 | No | ||
8 | SFRS2 | 50707 380593 | 1955 | 1.237 | -0.0095 | No | ||
9 | TYRO3 | 3130193 | 2073 | 1.158 | -0.0085 | No | ||
10 | ATF5 | 5670685 | 2075 | 1.156 | -0.0012 | No | ||
11 | RRM2 | 6350059 6940162 | 2198 | 1.075 | -0.0009 | No | ||
12 | USP52 | 3710215 6380133 | 2231 | 1.057 | 0.0041 | No | ||
13 | SFRS10 | 6130528 6400438 7040112 | 2363 | 0.992 | 0.0033 | No | ||
14 | MRPL40 | 2370215 | 2424 | 0.951 | 0.0061 | No | ||
15 | AP4M1 | 70609 3440128 | 2460 | 0.936 | 0.0101 | No | ||
16 | HIRA | 4480609 5270167 | 3125 | 0.601 | -0.0220 | No | ||
17 | PHF13 | 450435 | 3129 | 0.599 | -0.0184 | No | ||
18 | PAQR4 | 730736 | 3238 | 0.559 | -0.0206 | No | ||
19 | POLR2A | 5220647 | 3275 | 0.546 | -0.0191 | No | ||
20 | NUP62 | 1240128 | 3277 | 0.545 | -0.0157 | No | ||
21 | EPC1 | 1570050 5290095 6900193 | 3372 | 0.514 | -0.0175 | No | ||
22 | DDB2 | 3520341 4610168 4850184 4920717 | 3484 | 0.473 | -0.0205 | No | ||
23 | ATAD2 | 870242 2260687 | 3521 | 0.464 | -0.0195 | No | ||
24 | NELL2 | 2340725 4280301 5420008 | 3775 | 0.399 | -0.0307 | No | ||
25 | PVRL1 | 2570167 5220519 5890500 3190309 | 3838 | 0.388 | -0.0316 | No | ||
26 | ING3 | 110438 2060390 | 3864 | 0.380 | -0.0305 | No | ||
27 | CCNT1 | 2450563 5390184 | 4042 | 0.345 | -0.0379 | No | ||
28 | HMGN2 | 3140091 | 4113 | 0.332 | -0.0396 | No | ||
29 | ZBTB4 | 6450441 | 4175 | 0.322 | -0.0408 | No | ||
30 | HCN3 | 3940438 6840750 | 4223 | 0.314 | -0.0414 | No | ||
31 | IL4I1 | 3190161 | 4360 | 0.291 | -0.0469 | No | ||
32 | YBX2 | 3520441 | 4453 | 0.275 | -0.0501 | No | ||
33 | RANBP1 | 430215 1090180 | 4516 | 0.266 | -0.0518 | No | ||
34 | SEMA5A | 6200110 6520435 | 4608 | 0.252 | -0.0551 | No | ||
35 | KCND2 | 1170128 2100112 | 4632 | 0.250 | -0.0548 | No | ||
36 | RPS6KA5 | 2120563 7040546 | 4718 | 0.239 | -0.0579 | No | ||
37 | HOXC10 | 5360170 | 5028 | 0.204 | -0.0733 | No | ||
38 | PIM1 | 630047 | 5122 | 0.191 | -0.0771 | No | ||
39 | WNT3 | 2360685 | 5326 | 0.173 | -0.0870 | No | ||
40 | HNRPR | 2320440 2900601 4610008 | 5478 | 0.161 | -0.0942 | No | ||
41 | HNRPUL1 | 2120008 4920408 5570180 6370609 6770403 | 5720 | 0.143 | -0.1063 | No | ||
42 | ARID4A | 520156 1050707 | 5866 | 0.134 | -0.1133 | No | ||
43 | CASP8AP2 | 5910593 | 6044 | 0.121 | -0.1222 | No | ||
44 | MCM8 | 6130743 | 6068 | 0.120 | -0.1226 | No | ||
45 | EPHB1 | 4610056 | 6212 | 0.113 | -0.1297 | No | ||
46 | DNAJC9 | 6130019 | 6495 | 0.098 | -0.1443 | No | ||
47 | RAD51 | 6110450 6980280 | 6595 | 0.093 | -0.1491 | No | ||
48 | MCM2 | 5050139 | 6622 | 0.092 | -0.1499 | No | ||
49 | PODN | 3710068 | 6754 | 0.087 | -0.1564 | No | ||
50 | NRP2 | 4070400 5860041 6650446 | 7011 | 0.077 | -0.1698 | No | ||
51 | STK35 | 2360121 | 7089 | 0.075 | -0.1735 | No | ||
52 | IPO7 | 2190746 | 7698 | 0.057 | -0.2061 | No | ||
53 | GPRC5B | 2760114 | 7700 | 0.057 | -0.2058 | No | ||
54 | DMD | 1740041 3990332 | 8227 | 0.045 | -0.2340 | No | ||
55 | EFNA5 | 460707 2190519 | 8310 | 0.043 | -0.2381 | No | ||
56 | POLE2 | 6110041 | 8692 | 0.035 | -0.2586 | No | ||
57 | PAX6 | 1190025 | 8766 | 0.033 | -0.2623 | No | ||
58 | INSM1 | 3450671 | 8918 | 0.030 | -0.2703 | No | ||
59 | TREX2 | 4920707 | 9123 | 0.027 | -0.2812 | No | ||
60 | PRKDC | 1400072 4230541 | 9149 | 0.026 | -0.2824 | No | ||
61 | GABRB3 | 4150164 | 9725 | 0.016 | -0.3134 | No | ||
62 | CBX5 | 3830072 6290167 | 9780 | 0.015 | -0.3162 | No | ||
63 | ARHGAP6 | 2060121 | 9984 | 0.011 | -0.3271 | No | ||
64 | FBXO5 | 2630551 | 10381 | 0.005 | -0.3486 | No | ||
65 | NUP153 | 7000452 | 10430 | 0.004 | -0.3511 | No | ||
66 | STAG1 | 1190300 1400722 4590100 | 10654 | 0.000 | -0.3632 | No | ||
67 | CRK | 1230162 4780128 | 10922 | -0.004 | -0.3777 | No | ||
68 | RQCD1 | 1850139 | 11417 | -0.013 | -0.4043 | No | ||
69 | SMAD6 | 870504 | 11766 | -0.019 | -0.4231 | No | ||
70 | SLC6A4 | 2230372 | 11889 | -0.022 | -0.4295 | No | ||
71 | RHD | 4050168 | 11944 | -0.023 | -0.4323 | No | ||
72 | ABI2 | 940368 4200092 | 12143 | -0.028 | -0.4428 | No | ||
73 | FMO4 | 360735 | 12306 | -0.031 | -0.4514 | No | ||
74 | GRIA4 | 2640131 | 12364 | -0.033 | -0.4543 | No | ||
75 | JPH1 | 610739 | 12535 | -0.037 | -0.4633 | No | ||
76 | UXT | 110019 5080066 | 12655 | -0.041 | -0.4695 | No | ||
77 | PCSK1 | 2350148 | 13045 | -0.053 | -0.4902 | No | ||
78 | KCNA6 | 450291 1400086 1660291 2470576 | 13058 | -0.053 | -0.4905 | No | ||
79 | SP3 | 3840338 | 13400 | -0.066 | -0.5086 | No | ||
80 | TOPBP1 | 6020333 | 14021 | -0.105 | -0.5415 | No | ||
81 | FHOD1 | 2680279 | 14061 | -0.108 | -0.5429 | No | ||
82 | E2F7 | 4200056 | 14092 | -0.111 | -0.5438 | No | ||
83 | HNRPD | 4120021 | 14130 | -0.114 | -0.5451 | No | ||
84 | HS6ST3 | 5910138 | 14177 | -0.119 | -0.5468 | No | ||
85 | POLA2 | 940519 | 14472 | -0.155 | -0.5618 | No | ||
86 | ERBB2IP | 580253 1090672 | 14707 | -0.196 | -0.5732 | No | ||
87 | PPP1R8 | 6290292 | 14831 | -0.219 | -0.5785 | No | ||
88 | STAG2 | 4540132 | 14978 | -0.254 | -0.5847 | No | ||
89 | ADAMTS2 | 2650025 6370133 6840670 | 15018 | -0.265 | -0.5852 | No | ||
90 | CORT | 360008 2340092 | 15075 | -0.283 | -0.5864 | No | ||
91 | ASXL2 | 130670 | 15110 | -0.294 | -0.5864 | No | ||
92 | CDC45L | 70537 3130114 | 15150 | -0.305 | -0.5865 | No | ||
93 | WEE1 | 3390070 | 15186 | -0.317 | -0.5864 | No | ||
94 | HIST1H2AH | 3710333 | 15285 | -0.348 | -0.5895 | No | ||
95 | E2F3 | 50162 460180 | 15296 | -0.350 | -0.5878 | No | ||
96 | SLCO3A1 | 1050408 2370156 6110072 | 15329 | -0.360 | -0.5873 | No | ||
97 | SLC38A1 | 520465 | 15529 | -0.429 | -0.5953 | No | ||
98 | TBX6 | 4730139 6840647 | 15614 | -0.462 | -0.5969 | No | ||
99 | CLSPN | 2190239 2630687 5550632 | 15678 | -0.483 | -0.5973 | Yes | ||
100 | MSH2 | 6180273 | 15689 | -0.488 | -0.5947 | Yes | ||
101 | EZH2 | 6130605 6380524 | 15735 | -0.506 | -0.5939 | Yes | ||
102 | CDT1 | 3780682 | 15749 | -0.514 | -0.5914 | Yes | ||
103 | PHF15 | 6550066 6860673 | 15765 | -0.521 | -0.5889 | Yes | ||
104 | CDC6 | 4570296 5360600 | 15903 | -0.578 | -0.5926 | Yes | ||
105 | USP37 | 2470433 | 15910 | -0.580 | -0.5893 | Yes | ||
106 | MCM7 | 3290292 5220056 | 15954 | -0.607 | -0.5877 | Yes | ||
107 | CHD2 | 4070039 | 15963 | -0.611 | -0.5843 | Yes | ||
108 | RAB11B | 3990609 | 15972 | -0.614 | -0.5808 | Yes | ||
109 | MCM3 | 5570068 | 16006 | -0.627 | -0.5786 | Yes | ||
110 | MYH10 | 2640673 | 16190 | -0.718 | -0.5839 | Yes | ||
111 | DNAJC11 | 360465 3390215 | 16193 | -0.723 | -0.5794 | Yes | ||
112 | PHF5A | 2690519 | 16239 | -0.753 | -0.5771 | Yes | ||
113 | SNRPD1 | 4480162 | 16420 | -0.847 | -0.5815 | Yes | ||
114 | GMNN | 2630148 | 16617 | -0.965 | -0.5859 | Yes | ||
115 | NOLC1 | 2350195 | 16652 | -0.983 | -0.5815 | Yes | ||
116 | PPP1CC | 6380300 2510647 | 16673 | -0.993 | -0.5763 | Yes | ||
117 | AK2 | 4590458 4760195 6110097 | 16738 | -1.028 | -0.5732 | Yes | ||
118 | SFRS7 | 2760408 | 16758 | -1.040 | -0.5676 | Yes | ||
119 | UFD1L | 870020 | 16843 | -1.092 | -0.5652 | Yes | ||
120 | FANCD2 | 1850280 6840348 | 16917 | -1.150 | -0.5619 | Yes | ||
121 | E2F1 | 5360093 | 17060 | -1.284 | -0.5614 | Yes | ||
122 | MCM6 | 60092 540181 6510110 | 17090 | -1.312 | -0.5546 | Yes | ||
123 | SUMO1 | 1990364 2760338 6380195 | 17158 | -1.382 | -0.5495 | Yes | ||
124 | HNRPA1 | 4670398 5050687 | 17220 | -1.449 | -0.5435 | Yes | ||
125 | ILF3 | 940722 3190647 6520110 | 17224 | -1.453 | -0.5345 | Yes | ||
126 | NCL | 2360463 4540279 | 17306 | -1.541 | -0.5291 | Yes | ||
127 | CDC25A | 3800184 | 17420 | -1.670 | -0.5246 | Yes | ||
128 | STMN1 | 1990717 | 17470 | -1.733 | -0.5162 | Yes | ||
129 | POLE4 | 6860097 | 17513 | -1.773 | -0.5072 | Yes | ||
130 | ACO2 | 4230600 | 17559 | -1.827 | -0.4980 | Yes | ||
131 | PRPS1 | 6350129 | 17567 | -1.834 | -0.4867 | Yes | ||
132 | ALDH6A1 | 1770746 | 17581 | -1.852 | -0.4756 | Yes | ||
133 | H2AFZ | 1470168 | 17943 | -2.360 | -0.4802 | Yes | ||
134 | HTF9C | 3190048 4120132 | 18033 | -2.513 | -0.4690 | Yes | ||
135 | POLD3 | 6400278 | 18117 | -2.715 | -0.4562 | Yes | ||
136 | DNMT1 | 2260097 | 18211 | -2.929 | -0.4427 | Yes | ||
137 | PCNA | 940754 | 18279 | -3.090 | -0.4266 | Yes | ||
138 | NASP | 2260139 2940369 5130707 | 18304 | -3.185 | -0.4077 | Yes | ||
139 | SOAT1 | 1190019 | 18328 | -3.267 | -0.3881 | Yes | ||
140 | DCK | 6900411 | 18333 | -3.283 | -0.3675 | Yes | ||
141 | MCM4 | 2760673 5420711 | 18391 | -3.505 | -0.3483 | Yes | ||
142 | PHC1 | 520195 | 18445 | -3.750 | -0.3273 | Yes | ||
143 | BRMS1L | 6110609 | 18462 | -3.813 | -0.3039 | Yes | ||
144 | KPNB1 | 1690138 | 18464 | -3.826 | -0.2796 | Yes | ||
145 | RBL1 | 3130372 | 18465 | -3.829 | -0.2553 | Yes | ||
146 | CDCA7 | 3060097 | 18498 | -4.044 | -0.2313 | Yes | ||
147 | EED | 2320373 | 18506 | -4.095 | -0.2056 | Yes | ||
148 | ZCCHC8 | 2260332 2350487 | 18511 | -4.140 | -0.1795 | Yes | ||
149 | TMPO | 4050494 | 18542 | -4.448 | -0.1528 | Yes | ||
150 | UGCGL1 | 4230072 | 18553 | -4.528 | -0.1246 | Yes | ||
151 | CTCF | 5340017 | 18555 | -4.586 | -0.0955 | Yes | ||
152 | SFRS1 | 2360440 | 18577 | -4.846 | -0.0658 | Yes | ||
153 | PPM1D | 1690193 | 18592 | -5.188 | -0.0335 | Yes | ||
154 | GSPT1 | 5420050 | 18598 | -5.469 | 0.0010 | Yes |