Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
Upregulated in class | absentNotch |
GeneSet | V$E2F1DP1RB_01 |
Enrichment Score (ES) | -0.5792175 |
Normalized Enrichment Score (NES) | -1.7301717 |
Nominal p-value | 0.0 |
FDR q-value | 0.0055450425 |
FWER p-Value | 0.059 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | HIST1H2BK | 6130433 | 400 | 2.931 | -0.0032 | No | ||
2 | TLE3 | 580040 4730121 | 609 | 2.546 | 0.0015 | No | ||
3 | MXD3 | 6220014 | 879 | 2.166 | 0.0005 | No | ||
4 | UNG | 3130110 6100364 | 931 | 2.088 | 0.0109 | No | ||
5 | MAZ | 3360121 6940750 | 973 | 2.048 | 0.0215 | No | ||
6 | DPYSL2 | 2100427 3130112 5700324 | 1047 | 1.966 | 0.0299 | No | ||
7 | CLTA | 450010 | 1141 | 1.883 | 0.0367 | No | ||
8 | POLD1 | 4830026 | 1142 | 1.881 | 0.0485 | No | ||
9 | ACBD6 | 4200446 | 1685 | 1.462 | 0.0284 | No | ||
10 | SYNGR4 | 6520450 | 1888 | 1.286 | 0.0255 | No | ||
11 | SFRS2 | 50707 380593 | 1955 | 1.237 | 0.0297 | No | ||
12 | TYRO3 | 3130193 | 2073 | 1.158 | 0.0306 | No | ||
13 | ATF5 | 5670685 | 2075 | 1.156 | 0.0378 | No | ||
14 | RRM2 | 6350059 6940162 | 2198 | 1.075 | 0.0380 | No | ||
15 | USP52 | 3710215 6380133 | 2231 | 1.057 | 0.0429 | No | ||
16 | AP4M1 | 70609 3440128 | 2460 | 0.936 | 0.0364 | No | ||
17 | IMPDH2 | 5220138 | 2938 | 0.677 | 0.0149 | No | ||
18 | PHF13 | 450435 | 3129 | 0.599 | 0.0083 | No | ||
19 | PAQR4 | 730736 | 3238 | 0.559 | 0.0060 | No | ||
20 | POLR2A | 5220647 | 3275 | 0.546 | 0.0075 | No | ||
21 | NUP62 | 1240128 | 3277 | 0.545 | 0.0108 | No | ||
22 | DDB2 | 3520341 4610168 4850184 4920717 | 3484 | 0.473 | 0.0027 | No | ||
23 | ATAD2 | 870242 2260687 | 3521 | 0.464 | 0.0036 | No | ||
24 | NELL2 | 2340725 4280301 5420008 | 3775 | 0.399 | -0.0076 | No | ||
25 | PVRL1 | 2570167 5220519 5890500 3190309 | 3838 | 0.388 | -0.0085 | No | ||
26 | ING3 | 110438 2060390 | 3864 | 0.380 | -0.0074 | No | ||
27 | CCNT1 | 2450563 5390184 | 4042 | 0.345 | -0.0149 | No | ||
28 | HMGN2 | 3140091 | 4113 | 0.332 | -0.0166 | No | ||
29 | ZBTB4 | 6450441 | 4175 | 0.322 | -0.0179 | No | ||
30 | HCN3 | 3940438 6840750 | 4223 | 0.314 | -0.0184 | No | ||
31 | IL4I1 | 3190161 | 4360 | 0.291 | -0.0240 | No | ||
32 | YBX2 | 3520441 | 4453 | 0.275 | -0.0272 | No | ||
33 | RPS6KA5 | 2120563 7040546 | 4718 | 0.239 | -0.0400 | No | ||
34 | HOXC10 | 5360170 | 5028 | 0.204 | -0.0555 | No | ||
35 | CTDSP1 | 6650215 6940731 | 5055 | 0.200 | -0.0556 | No | ||
36 | PIM1 | 630047 | 5122 | 0.191 | -0.0580 | No | ||
37 | MDGA1 | 1170139 | 5276 | 0.177 | -0.0652 | No | ||
38 | ONECUT1 | 6450136 | 5368 | 0.169 | -0.0690 | No | ||
39 | HNRPR | 2320440 2900601 4610008 | 5478 | 0.161 | -0.0739 | No | ||
40 | HNRPUL1 | 2120008 4920408 5570180 6370609 6770403 | 5720 | 0.143 | -0.0861 | No | ||
41 | ARID4A | 520156 1050707 | 5866 | 0.134 | -0.0931 | No | ||
42 | CASP8AP2 | 5910593 | 6044 | 0.121 | -0.1019 | No | ||
43 | MCM8 | 6130743 | 6068 | 0.120 | -0.1024 | No | ||
44 | ATRX | 2340039 3610132 4210373 | 6109 | 0.118 | -0.1038 | No | ||
45 | EPHB1 | 4610056 | 6212 | 0.113 | -0.1086 | No | ||
46 | PNMA3 | 3170309 | 6471 | 0.099 | -0.1220 | No | ||
47 | DNAJC9 | 6130019 | 6495 | 0.098 | -0.1226 | No | ||
48 | RAD51 | 6110450 6980280 | 6595 | 0.093 | -0.1274 | No | ||
49 | MCM2 | 5050139 | 6622 | 0.092 | -0.1282 | No | ||
50 | PODN | 3710068 | 6754 | 0.087 | -0.1348 | No | ||
51 | NRP2 | 4070400 5860041 6650446 | 7011 | 0.077 | -0.1481 | No | ||
52 | STK35 | 2360121 | 7089 | 0.075 | -0.1518 | No | ||
53 | POU4F1 | 2260315 | 7281 | 0.069 | -0.1618 | No | ||
54 | IPO7 | 2190746 | 7698 | 0.057 | -0.1839 | No | ||
55 | GPRC5B | 2760114 | 7700 | 0.057 | -0.1836 | No | ||
56 | SEZ6 | 3450722 | 8076 | 0.049 | -0.2036 | No | ||
57 | DMD | 1740041 3990332 | 8227 | 0.045 | -0.2115 | No | ||
58 | POLE2 | 6110041 | 8692 | 0.035 | -0.2364 | No | ||
59 | PAX6 | 1190025 | 8766 | 0.033 | -0.2401 | No | ||
60 | LHX5 | 2350097 | 9340 | 0.022 | -0.2710 | No | ||
61 | RET | 3850746 | 9609 | 0.018 | -0.2854 | No | ||
62 | GABRB3 | 4150164 | 9725 | 0.016 | -0.2915 | No | ||
63 | CBX5 | 3830072 6290167 | 9780 | 0.015 | -0.2944 | No | ||
64 | ARHGAP6 | 2060121 | 9984 | 0.011 | -0.3053 | No | ||
65 | PEG3 | 3710020 | 10019 | 0.011 | -0.3070 | No | ||
66 | FBXO5 | 2630551 | 10381 | 0.005 | -0.3266 | No | ||
67 | NPR3 | 1580239 | 11102 | -0.007 | -0.3655 | No | ||
68 | SMAD6 | 870504 | 11766 | -0.019 | -0.4013 | No | ||
69 | SLC6A4 | 2230372 | 11889 | -0.022 | -0.4078 | No | ||
70 | RHD | 4050168 | 11944 | -0.023 | -0.4105 | No | ||
71 | LIG1 | 1980438 4540112 5570609 | 11970 | -0.024 | -0.4117 | No | ||
72 | FMO4 | 360735 | 12306 | -0.031 | -0.4297 | No | ||
73 | GRIA4 | 2640131 | 12364 | -0.033 | -0.4326 | No | ||
74 | PCSK1 | 2350148 | 13045 | -0.053 | -0.4691 | No | ||
75 | KCNA6 | 450291 1400086 1660291 2470576 | 13058 | -0.053 | -0.4694 | No | ||
76 | SP3 | 3840338 | 13400 | -0.066 | -0.4874 | No | ||
77 | TOPBP1 | 6020333 | 14021 | -0.105 | -0.5203 | No | ||
78 | FHOD1 | 2680279 | 14061 | -0.108 | -0.5218 | No | ||
79 | E2F7 | 4200056 | 14092 | -0.111 | -0.5227 | No | ||
80 | HNRPD | 4120021 | 14130 | -0.114 | -0.5240 | No | ||
81 | HS6ST3 | 5910138 | 14177 | -0.119 | -0.5257 | No | ||
82 | POLA2 | 940519 | 14472 | -0.155 | -0.5407 | No | ||
83 | OLFML3 | 7100463 | 14657 | -0.186 | -0.5495 | No | ||
84 | PPP1R8 | 6290292 | 14831 | -0.219 | -0.5575 | No | ||
85 | STAG2 | 4540132 | 14978 | -0.254 | -0.5638 | No | ||
86 | ADAMTS2 | 2650025 6370133 6840670 | 15018 | -0.265 | -0.5642 | No | ||
87 | CORT | 360008 2340092 | 15075 | -0.283 | -0.5655 | No | ||
88 | ASXL2 | 130670 | 15110 | -0.294 | -0.5655 | No | ||
89 | WEE1 | 3390070 | 15186 | -0.317 | -0.5675 | No | ||
90 | KLF4 | 1850022 3830239 5570750 | 15239 | -0.335 | -0.5682 | No | ||
91 | HIST1H2AH | 3710333 | 15285 | -0.348 | -0.5685 | No | ||
92 | SLCO3A1 | 1050408 2370156 6110072 | 15329 | -0.360 | -0.5686 | No | ||
93 | PAPOLG | 2470400 | 15405 | -0.388 | -0.5702 | No | ||
94 | SLC38A1 | 520465 | 15529 | -0.429 | -0.5742 | No | ||
95 | TBX6 | 4730139 6840647 | 15614 | -0.462 | -0.5758 | No | ||
96 | CLSPN | 2190239 2630687 5550632 | 15678 | -0.483 | -0.5762 | Yes | ||
97 | MSH2 | 6180273 | 15689 | -0.488 | -0.5737 | Yes | ||
98 | EZH2 | 6130605 6380524 | 15735 | -0.506 | -0.5729 | Yes | ||
99 | CDT1 | 3780682 | 15749 | -0.514 | -0.5704 | Yes | ||
100 | PHF15 | 6550066 6860673 | 15765 | -0.521 | -0.5679 | Yes | ||
101 | CDC6 | 4570296 5360600 | 15903 | -0.578 | -0.5717 | Yes | ||
102 | USP37 | 2470433 | 15910 | -0.580 | -0.5684 | Yes | ||
103 | MCM7 | 3290292 5220056 | 15954 | -0.607 | -0.5669 | Yes | ||
104 | SLC25A14 | 4760180 | 15967 | -0.612 | -0.5637 | Yes | ||
105 | RAB11B | 3990609 | 15972 | -0.614 | -0.5601 | Yes | ||
106 | MCM3 | 5570068 | 16006 | -0.627 | -0.5579 | Yes | ||
107 | MYH10 | 2640673 | 16190 | -0.718 | -0.5633 | Yes | ||
108 | DNAJC11 | 360465 3390215 | 16193 | -0.723 | -0.5589 | Yes | ||
109 | MAPT | 360706 1230706 | 16266 | -0.764 | -0.5580 | Yes | ||
110 | SNRPD1 | 4480162 | 16420 | -0.847 | -0.5610 | Yes | ||
111 | MAT2A | 4070026 4730079 6020280 | 16565 | -0.938 | -0.5629 | Yes | ||
112 | GMNN | 2630148 | 16617 | -0.965 | -0.5596 | Yes | ||
113 | NOLC1 | 2350195 | 16652 | -0.983 | -0.5552 | Yes | ||
114 | PPP1CC | 6380300 2510647 | 16673 | -0.993 | -0.5501 | Yes | ||
115 | AK2 | 4590458 4760195 6110097 | 16738 | -1.028 | -0.5471 | Yes | ||
116 | SFRS7 | 2760408 | 16758 | -1.040 | -0.5416 | Yes | ||
117 | E2F1 | 5360093 | 17060 | -1.284 | -0.5498 | Yes | ||
118 | MCM6 | 60092 540181 6510110 | 17090 | -1.312 | -0.5431 | Yes | ||
119 | RBBP7 | 430113 450450 2370309 | 17109 | -1.334 | -0.5357 | Yes | ||
120 | SUMO1 | 1990364 2760338 6380195 | 17158 | -1.382 | -0.5296 | Yes | ||
121 | HNRPA1 | 4670398 5050687 | 17220 | -1.449 | -0.5238 | Yes | ||
122 | ILF3 | 940722 3190647 6520110 | 17224 | -1.453 | -0.5149 | Yes | ||
123 | NCL | 2360463 4540279 | 17306 | -1.541 | -0.5096 | Yes | ||
124 | CDC25A | 3800184 | 17420 | -1.670 | -0.5052 | Yes | ||
125 | STMN1 | 1990717 | 17470 | -1.733 | -0.4970 | Yes | ||
126 | POLE4 | 6860097 | 17513 | -1.773 | -0.4881 | Yes | ||
127 | PRPS1 | 6350129 | 17567 | -1.834 | -0.4795 | Yes | ||
128 | ALDH6A1 | 1770746 | 17581 | -1.852 | -0.4685 | Yes | ||
129 | EIF4A1 | 1990341 2810300 | 17929 | -2.341 | -0.4726 | Yes | ||
130 | H2AFZ | 1470168 | 17943 | -2.360 | -0.4585 | Yes | ||
131 | RFC1 | 1190673 | 18061 | -2.570 | -0.4487 | Yes | ||
132 | POLD3 | 6400278 | 18117 | -2.715 | -0.4346 | Yes | ||
133 | DNMT1 | 2260097 | 18211 | -2.929 | -0.4213 | Yes | ||
134 | PCNA | 940754 | 18279 | -3.090 | -0.4055 | Yes | ||
135 | NASP | 2260139 2940369 5130707 | 18304 | -3.185 | -0.3868 | Yes | ||
136 | SOAT1 | 1190019 | 18328 | -3.267 | -0.3675 | Yes | ||
137 | DCK | 6900411 | 18333 | -3.283 | -0.3471 | Yes | ||
138 | PHC1 | 520195 | 18445 | -3.750 | -0.3295 | Yes | ||
139 | BRMS1L | 6110609 | 18462 | -3.813 | -0.3064 | Yes | ||
140 | KPNB1 | 1690138 | 18464 | -3.826 | -0.2825 | Yes | ||
141 | CDCA7 | 3060097 | 18498 | -4.044 | -0.2589 | Yes | ||
142 | EED | 2320373 | 18506 | -4.095 | -0.2335 | Yes | ||
143 | ZCCHC8 | 2260332 2350487 | 18511 | -4.140 | -0.2077 | Yes | ||
144 | TMPO | 4050494 | 18542 | -4.448 | -0.1814 | Yes | ||
145 | UGCGL1 | 4230072 | 18553 | -4.528 | -0.1535 | Yes | ||
146 | CTCF | 5340017 | 18555 | -4.586 | -0.1247 | Yes | ||
147 | SFRS1 | 2360440 | 18577 | -4.846 | -0.0954 | Yes | ||
148 | MAPK6 | 6760520 | 18578 | -4.847 | -0.0650 | Yes | ||
149 | PPM1D | 1690193 | 18592 | -5.188 | -0.0331 | Yes | ||
150 | GSPT1 | 5420050 | 18598 | -5.469 | 0.0010 | Yes |