Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
Upregulated in class | truncNotch |
GeneSet | V$E12_Q6 |
Enrichment Score (ES) | 0.44265598 |
Normalized Enrichment Score (NES) | 1.2915655 |
Nominal p-value | 0.026755853 |
FDR q-value | 0.99400496 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | HMGA1 | 6580408 | 64 | 4.491 | 0.0352 | Yes | ||
2 | HEYL | 5860528 | 73 | 4.355 | 0.0723 | Yes | ||
3 | AIG1 | 2450091 | 90 | 4.174 | 0.1074 | Yes | ||
4 | PTK2B | 4730411 | 216 | 3.448 | 0.1304 | Yes | ||
5 | ENO3 | 5270136 | 264 | 3.305 | 0.1563 | Yes | ||
6 | ELOVL1 | 2450019 4760138 5340685 | 268 | 3.294 | 0.1845 | Yes | ||
7 | GFRA1 | 3610152 | 436 | 2.845 | 0.2000 | Yes | ||
8 | ARID5A | 2450133 | 489 | 2.734 | 0.2207 | Yes | ||
9 | DEF6 | 840593 | 554 | 2.636 | 0.2400 | Yes | ||
10 | SLC37A4 | 6400079 | 559 | 2.633 | 0.2624 | Yes | ||
11 | PPP1R9B | 3130619 | 599 | 2.558 | 0.2824 | Yes | ||
12 | PPOX | 2640678 3850102 | 660 | 2.473 | 0.3004 | Yes | ||
13 | SELL | 1190500 | 841 | 2.211 | 0.3097 | Yes | ||
14 | SASH1 | 4070270 | 893 | 2.147 | 0.3255 | Yes | ||
15 | PSTPIP1 | 3190156 | 910 | 2.121 | 0.3429 | Yes | ||
16 | HES6 | 540411 6550504 | 950 | 2.067 | 0.3586 | Yes | ||
17 | GNAS | 630441 1850373 4050152 | 1257 | 1.771 | 0.3572 | Yes | ||
18 | SMAD3 | 6450671 | 1267 | 1.764 | 0.3719 | Yes | ||
19 | CRELD1 | 2060253 | 1321 | 1.721 | 0.3839 | Yes | ||
20 | TTC17 | 2470440 | 1526 | 1.553 | 0.3862 | Yes | ||
21 | CKM | 1450524 | 1583 | 1.513 | 0.3962 | Yes | ||
22 | SIPA1 | 5220687 | 1613 | 1.500 | 0.4076 | Yes | ||
23 | CENTB1 | 2120093 | 1983 | 1.219 | 0.3981 | Yes | ||
24 | RANGAP1 | 2320593 6650601 | 2049 | 1.171 | 0.4046 | Yes | ||
25 | TNFAIP1 | 6940593 | 2076 | 1.154 | 0.4132 | Yes | ||
26 | CNNM2 | 2650100 | 2162 | 1.096 | 0.4180 | Yes | ||
27 | STC2 | 4920601 | 2304 | 1.019 | 0.4191 | Yes | ||
28 | ARHGAP24 | 540278 4540025 | 2379 | 0.981 | 0.4236 | Yes | ||
29 | LRP10 | 1580128 | 2443 | 0.944 | 0.4283 | Yes | ||
30 | IGF2 | 6510020 | 2497 | 0.911 | 0.4333 | Yes | ||
31 | POFUT1 | 1570458 | 2548 | 0.877 | 0.4381 | Yes | ||
32 | CENTG3 | 2470079 4610092 5050170 | 2653 | 0.825 | 0.4396 | Yes | ||
33 | CORO2A | 3840605 6620390 | 2729 | 0.785 | 0.4423 | Yes | ||
34 | TPM3 | 670600 3170296 5670167 6650471 | 2876 | 0.702 | 0.4404 | Yes | ||
35 | IGFBP5 | 2360592 | 2943 | 0.674 | 0.4427 | Yes | ||
36 | CAMK1D | 1660100 2350309 | 3247 | 0.557 | 0.4310 | No | ||
37 | FGF8 | 6350504 | 3474 | 0.478 | 0.4229 | No | ||
38 | PLCB3 | 4670402 | 3504 | 0.469 | 0.4253 | No | ||
39 | IGSF8 | 1580592 | 3555 | 0.457 | 0.4266 | No | ||
40 | SEMA3F | 5420601 6770731 | 3572 | 0.452 | 0.4296 | No | ||
41 | HOXB7 | 4540706 4610358 | 3662 | 0.426 | 0.4284 | No | ||
42 | ACTN3 | 3140541 6480598 | 3698 | 0.418 | 0.4302 | No | ||
43 | GJB2 | 5900609 6200487 | 3788 | 0.397 | 0.4288 | No | ||
44 | SYT4 | 5080193 | 3989 | 0.355 | 0.4210 | No | ||
45 | LRP5 | 2100397 3170484 | 4102 | 0.333 | 0.4178 | No | ||
46 | HMGN2 | 3140091 | 4113 | 0.332 | 0.4201 | No | ||
47 | EYA3 | 1580195 6510632 | 4253 | 0.309 | 0.4152 | No | ||
48 | INVS | 4200632 6620528 | 4311 | 0.298 | 0.4147 | No | ||
49 | PHACTR3 | 3850435 5900445 | 4336 | 0.294 | 0.4159 | No | ||
50 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 4342 | 0.293 | 0.4182 | No | ||
51 | TNNC2 | 3840079 | 4375 | 0.287 | 0.4189 | No | ||
52 | CDH2 | 520435 2450451 2760025 6650477 | 4395 | 0.285 | 0.4203 | No | ||
53 | ITGB4 | 1740021 3840482 | 4518 | 0.265 | 0.4160 | No | ||
54 | NOL4 | 5050446 5360519 | 5049 | 0.201 | 0.3890 | No | ||
55 | MDGA1 | 1170139 | 5276 | 0.177 | 0.3783 | No | ||
56 | CYP26A1 | 380022 2690600 | 5361 | 0.170 | 0.3752 | No | ||
57 | BRUNOL4 | 4490452 5080451 | 5441 | 0.164 | 0.3723 | No | ||
58 | DNMT3A | 4050068 4810717 | 5504 | 0.159 | 0.3703 | No | ||
59 | PRKAG2 | 2340100 | 5527 | 0.157 | 0.3705 | No | ||
60 | GPD1 | 2480095 | 5576 | 0.154 | 0.3692 | No | ||
61 | GGN | 1410528 4210082 5290170 | 5736 | 0.142 | 0.3618 | No | ||
62 | COL4A3 | 5910075 | 5980 | 0.125 | 0.3497 | No | ||
63 | RASSF2 | 2480079 5720546 | 5991 | 0.124 | 0.3502 | No | ||
64 | POU2F3 | 2030601 | 6032 | 0.122 | 0.3491 | No | ||
65 | FSCN2 | 1230039 | 6192 | 0.113 | 0.3415 | No | ||
66 | CALN1 | 3610722 | 6262 | 0.110 | 0.3387 | No | ||
67 | CDH5 | 5340487 | 6263 | 0.110 | 0.3396 | No | ||
68 | CALB1 | 460070 | 6266 | 0.110 | 0.3404 | No | ||
69 | ROBO3 | 6550408 | 6486 | 0.098 | 0.3294 | No | ||
70 | CFL1 | 2340735 | 6499 | 0.097 | 0.3296 | No | ||
71 | IRX6 | 4590025 | 6535 | 0.096 | 0.3285 | No | ||
72 | NEURL | 5390538 | 6536 | 0.096 | 0.3293 | No | ||
73 | ALDH1A2 | 2320301 | 6592 | 0.093 | 0.3272 | No | ||
74 | MTUS1 | 780348 4920609 | 6880 | 0.082 | 0.3123 | No | ||
75 | CHST9 | 4560092 | 7006 | 0.077 | 0.3062 | No | ||
76 | CCNL2 | 6520167 | 7100 | 0.075 | 0.3018 | No | ||
77 | DOC2A | 6020121 | 7240 | 0.070 | 0.2949 | No | ||
78 | NPEPPS | 2630731 | 7313 | 0.068 | 0.2915 | No | ||
79 | GDPD2 | 7000040 | 7356 | 0.066 | 0.2898 | No | ||
80 | ODC1 | 5670168 | 7414 | 0.064 | 0.2873 | No | ||
81 | SOST | 1170195 | 7430 | 0.064 | 0.2870 | No | ||
82 | DNAJB5 | 2900215 | 7520 | 0.061 | 0.2827 | No | ||
83 | ZNF205 | 6900022 | 7713 | 0.057 | 0.2728 | No | ||
84 | MYH14 | 4010017 | 7821 | 0.055 | 0.2675 | No | ||
85 | NEGR1 | 1940731 5130170 | 7990 | 0.050 | 0.2588 | No | ||
86 | FGF11 | 840292 | 7997 | 0.050 | 0.2589 | No | ||
87 | EIF2C1 | 6900551 | 8005 | 0.050 | 0.2590 | No | ||
88 | RTN4RL2 | 6450609 | 8212 | 0.045 | 0.2482 | No | ||
89 | MT3 | 1450537 | 8267 | 0.044 | 0.2456 | No | ||
90 | ARHGEF12 | 3990195 | 8309 | 0.043 | 0.2438 | No | ||
91 | NR4A1 | 6290161 | 8346 | 0.042 | 0.2422 | No | ||
92 | CPZ | 70193 | 8367 | 0.042 | 0.2415 | No | ||
93 | MYOZ3 | 1990138 | 8446 | 0.041 | 0.2376 | No | ||
94 | GFAP | 2060092 | 8686 | 0.035 | 0.2249 | No | ||
95 | ANK2 | 6510546 | 9109 | 0.027 | 0.2023 | No | ||
96 | TREX2 | 4920707 | 9123 | 0.027 | 0.2018 | No | ||
97 | TEAD4 | 1850239 6380519 | 9212 | 0.025 | 0.1972 | No | ||
98 | ARVCF | 2190537 | 9315 | 0.023 | 0.1919 | No | ||
99 | GRIA1 | 1340152 3780750 4920440 | 9369 | 0.022 | 0.1892 | No | ||
100 | FOXI1 | 3710095 6620195 | 9372 | 0.022 | 0.1893 | No | ||
101 | DLL3 | 4010093 | 9379 | 0.022 | 0.1892 | No | ||
102 | SFTPC | 3290133 | 9407 | 0.021 | 0.1879 | No | ||
103 | MTSS1 | 780435 2370114 | 9419 | 0.021 | 0.1875 | No | ||
104 | KLHL13 | 6590731 | 9475 | 0.020 | 0.1847 | No | ||
105 | PTPRJ | 4010707 | 9555 | 0.019 | 0.1805 | No | ||
106 | ANKRD2 | 6590427 | 9938 | 0.012 | 0.1599 | No | ||
107 | GPM6B | 6220458 | 9946 | 0.012 | 0.1596 | No | ||
108 | TCF2 | 870338 5050632 | 9956 | 0.012 | 0.1593 | No | ||
109 | COL4A4 | 1050541 | 10339 | 0.005 | 0.1386 | No | ||
110 | LAMA5 | 2680722 | 10718 | -0.001 | 0.1181 | No | ||
111 | CHRDL1 | 1580037 6380204 | 10750 | -0.001 | 0.1164 | No | ||
112 | PPARA | 2060026 | 10754 | -0.001 | 0.1163 | No | ||
113 | SOX17 | 5270551 | 10945 | -0.005 | 0.1060 | No | ||
114 | BMP6 | 2100128 | 10969 | -0.005 | 0.1048 | No | ||
115 | NHLH1 | 6100452 | 11094 | -0.007 | 0.0981 | No | ||
116 | ASB14 | 5860427 | 11218 | -0.009 | 0.0915 | No | ||
117 | CPA4 | 3610100 | 11357 | -0.012 | 0.0842 | No | ||
118 | NBL1 | 2480021 | 11522 | -0.015 | 0.0754 | No | ||
119 | TGFB3 | 1070041 | 11664 | -0.017 | 0.0679 | No | ||
120 | NTRK2 | 6220463 | 11743 | -0.019 | 0.0638 | No | ||
121 | AP1S2 | 780279 4280707 | 11872 | -0.022 | 0.0571 | No | ||
122 | GATA2 | 6590280 | 11962 | -0.024 | 0.0525 | No | ||
123 | WTAP | 4010176 | 12064 | -0.026 | 0.0472 | No | ||
124 | TRIM23 | 580168 6510672 | 12319 | -0.032 | 0.0337 | No | ||
125 | CHRND | 840403 2260670 | 12359 | -0.033 | 0.0319 | No | ||
126 | DLL1 | 1770377 | 12441 | -0.035 | 0.0278 | No | ||
127 | SLC12A5 | 1980692 | 12502 | -0.036 | 0.0248 | No | ||
128 | HSD11B2 | 5900053 | 12830 | -0.045 | 0.0075 | No | ||
129 | KCNB1 | 3610035 | 12940 | -0.049 | 0.0020 | No | ||
130 | GPR37 | 2320093 | 12970 | -0.050 | 0.0009 | No | ||
131 | PACSIN3 | 4540369 4540400 5360037 6940129 | 13171 | -0.057 | -0.0095 | No | ||
132 | UNC13B | 130735 | 13197 | -0.058 | -0.0103 | No | ||
133 | SORCS2 | 6350520 | 13412 | -0.066 | -0.0214 | No | ||
134 | RAB26 | 5910025 | 13536 | -0.073 | -0.0274 | No | ||
135 | SLC24A3 | 5080707 | 13598 | -0.076 | -0.0301 | No | ||
136 | SIM1 | 1770332 | 13727 | -0.083 | -0.0363 | No | ||
137 | FYN | 2100468 4760520 4850687 | 13831 | -0.091 | -0.0411 | No | ||
138 | WDR20 | 1240373 | 13897 | -0.095 | -0.0438 | No | ||
139 | RAPGEF4 | 6100563 | 13939 | -0.098 | -0.0452 | No | ||
140 | CANX | 4760402 | 13972 | -0.101 | -0.0461 | No | ||
141 | HR | 2690095 6200300 | 14038 | -0.106 | -0.0487 | No | ||
142 | NFATC4 | 2470735 | 14059 | -0.108 | -0.0488 | No | ||
143 | PCDH15 | 7000438 | 14124 | -0.114 | -0.0513 | No | ||
144 | CXCL14 | 840114 6450324 | 14190 | -0.121 | -0.0538 | No | ||
145 | SSH2 | 360056 | 14301 | -0.133 | -0.0586 | No | ||
146 | USP2 | 1190292 1240253 4850035 | 14344 | -0.138 | -0.0597 | No | ||
147 | KCNK12 | 4070072 | 14361 | -0.140 | -0.0594 | No | ||
148 | ITGA6 | 3830129 | 14632 | -0.181 | -0.0724 | No | ||
149 | HIF3A | 2630053 2680102 6450364 | 14680 | -0.189 | -0.0734 | No | ||
150 | DSCAM | 1780050 2450731 2810438 | 14695 | -0.193 | -0.0725 | No | ||
151 | PIM2 | 840136 5720692 7100577 | 14884 | -0.231 | -0.0807 | No | ||
152 | NTRK3 | 4050687 4070167 4610026 6100484 | 14912 | -0.238 | -0.0801 | No | ||
153 | SCG2 | 5670438 130671 | 15074 | -0.283 | -0.0864 | No | ||
154 | TNFRSF21 | 6380100 | 15335 | -0.363 | -0.0973 | No | ||
155 | SORT1 | 1850242 2320632 3870537 | 15511 | -0.424 | -0.1032 | No | ||
156 | CAMK2A | 1740333 1940112 4150292 | 15526 | -0.428 | -0.1002 | No | ||
157 | FUT8 | 1340068 2340056 | 15634 | -0.470 | -0.1020 | No | ||
158 | RIN1 | 510593 | 15763 | -0.520 | -0.1045 | No | ||
159 | ADAM12 | 3390132 4070347 | 15796 | -0.531 | -0.1016 | No | ||
160 | TNFSF13 | 2650170 | 15983 | -0.616 | -0.1064 | No | ||
161 | GRB7 | 2100471 | 16145 | -0.695 | -0.1091 | No | ||
162 | PLAGL2 | 1770148 | 16346 | -0.808 | -0.1130 | No | ||
163 | KCNN3 | 6520600 6420138 | 16430 | -0.856 | -0.1101 | No | ||
164 | ELMO1 | 110338 1190451 1580148 1850609 2350706 2370369 2450129 3840113 4150184 4280079 6290066 6380435 6770494 7100180 | 16641 | -0.978 | -0.1131 | No | ||
165 | WNT6 | 4570364 | 16778 | -1.055 | -0.1114 | No | ||
166 | CORO2B | 2340035 4850390 | 17064 | -1.290 | -0.1157 | No | ||
167 | NUP88 | 2510044 6760180 | 17159 | -1.383 | -0.1089 | No | ||
168 | EGLN1 | 2480180 3120253 6110195 | 17177 | -1.403 | -0.0977 | No | ||
169 | POLR1D | 70082 450750 6040458 | 17329 | -1.565 | -0.0924 | No | ||
170 | MFNG | 1770242 4280348 | 17520 | -1.781 | -0.0874 | No | ||
171 | SLC23A2 | 6660722 | 17533 | -1.795 | -0.0726 | No | ||
172 | RUNX1 | 3840711 | 17573 | -1.837 | -0.0589 | No | ||
173 | GRB2 | 6650398 | 17634 | -1.909 | -0.0457 | No | ||
174 | LNX2 | 3130025 | 17659 | -1.945 | -0.0302 | No | ||
175 | OSR1 | 1500025 | 18183 | -2.843 | -0.0341 | No | ||
176 | NEDD4L | 6380368 | 18321 | -3.241 | -0.0136 | No | ||
177 | RRAGC | 5910348 | 18368 | -3.426 | 0.0134 | No |