Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
Upregulated in class | truncNotch |
GeneSet | V$BACH1_01 |
Enrichment Score (ES) | 0.421127 |
Normalized Enrichment Score (NES) | 1.229961 |
Nominal p-value | 0.051779937 |
FDR q-value | 0.9867539 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | ALDOA | 6290672 | 20 | 5.593 | 0.0337 | Yes | ||
2 | GNGT2 | 540176 | 50 | 4.702 | 0.0613 | Yes | ||
3 | HMGA1 | 6580408 | 64 | 4.491 | 0.0885 | Yes | ||
4 | EDG5 | 2640300 | 150 | 3.760 | 0.1073 | Yes | ||
5 | ABCD1 | 5670373 | 248 | 3.366 | 0.1229 | Yes | ||
6 | BCL9L | 6940053 | 298 | 3.207 | 0.1402 | Yes | ||
7 | ALS2CR2 | 6450128 7100092 | 355 | 3.052 | 0.1561 | Yes | ||
8 | ABCA2 | 5050039 | 385 | 2.965 | 0.1730 | Yes | ||
9 | ITPKC | 5420021 | 517 | 2.678 | 0.1825 | Yes | ||
10 | TRAPPC3 | 2030176 6020609 6590373 6760019 | 531 | 2.656 | 0.1983 | Yes | ||
11 | RPS6KA4 | 2190524 | 536 | 2.652 | 0.2145 | Yes | ||
12 | LMNA | 520471 1500075 3190167 4210020 | 594 | 2.565 | 0.2274 | Yes | ||
13 | PPP1R9B | 3130619 | 599 | 2.558 | 0.2431 | Yes | ||
14 | ENO1 | 5340128 | 621 | 2.530 | 0.2577 | Yes | ||
15 | HDAC3 | 4060072 | 777 | 2.296 | 0.2635 | Yes | ||
16 | CAMKK1 | 6370324 | 784 | 2.283 | 0.2774 | Yes | ||
17 | SQSTM1 | 6550056 | 884 | 2.162 | 0.2854 | Yes | ||
18 | RAB3D | 4210253 | 915 | 2.109 | 0.2969 | Yes | ||
19 | PKP3 | 3710048 | 947 | 2.072 | 0.3081 | Yes | ||
20 | ROM1 | 3130685 | 978 | 2.044 | 0.3192 | Yes | ||
21 | ADCK4 | 1660180 | 1033 | 1.985 | 0.3286 | Yes | ||
22 | NCDN | 50040 1980739 3520603 | 1097 | 1.916 | 0.3371 | Yes | ||
23 | SNPH | 2680484 | 1128 | 1.890 | 0.3472 | Yes | ||
24 | UBE2C | 6130017 | 1159 | 1.873 | 0.3572 | Yes | ||
25 | TNFRSF12A | 4810253 | 1329 | 1.716 | 0.3587 | Yes | ||
26 | DCTN2 | 540471 3780717 | 1404 | 1.640 | 0.3649 | Yes | ||
27 | TAGLN2 | 4560121 | 1433 | 1.619 | 0.3734 | Yes | ||
28 | BAG2 | 2900324 | 1539 | 1.540 | 0.3773 | Yes | ||
29 | LTB4R2 | 1990746 | 1553 | 1.532 | 0.3861 | Yes | ||
30 | ABHD4 | 6760450 | 1687 | 1.462 | 0.3880 | Yes | ||
31 | SERTAD1 | 2680332 | 1805 | 1.348 | 0.3900 | Yes | ||
32 | ECM1 | 940068 5390309 | 1812 | 1.342 | 0.3980 | Yes | ||
33 | SFRS2 | 50707 380593 | 1955 | 1.237 | 0.3980 | Yes | ||
34 | HSPB8 | 540563 | 2061 | 1.166 | 0.3995 | Yes | ||
35 | AP2A2 | 130082 | 2178 | 1.086 | 0.4000 | Yes | ||
36 | EPHB2 | 1090288 1410377 2100541 | 2246 | 1.047 | 0.4029 | Yes | ||
37 | NDRG2 | 450403 | 2275 | 1.032 | 0.4077 | Yes | ||
38 | PADI4 | 1740075 4810441 | 2336 | 1.002 | 0.4107 | Yes | ||
39 | UBE2E3 | 2030347 3840471 | 2353 | 0.996 | 0.4160 | Yes | ||
40 | MNT | 4920575 | 2373 | 0.985 | 0.4211 | Yes | ||
41 | EEF1A1 | 1980193 1990195 4670735 | 2634 | 0.835 | 0.4122 | No | ||
42 | DDIT3 | 780373 | 2707 | 0.796 | 0.4132 | No | ||
43 | SCRN1 | 6040025 6580019 | 2727 | 0.786 | 0.4171 | No | ||
44 | GABARAPL1 | 2810458 | 2934 | 0.678 | 0.4101 | No | ||
45 | CDH23 | 4250242 5290397 6550397 | 3213 | 0.570 | 0.3986 | No | ||
46 | ACPP | 2470152 1780593 2690524 | 3322 | 0.530 | 0.3960 | No | ||
47 | RTN4 | 50725 630647 870097 870184 | 3380 | 0.512 | 0.3961 | No | ||
48 | S100A10 | 6350010 | 3389 | 0.509 | 0.3988 | No | ||
49 | ADRA1A | 1230446 2260390 | 3399 | 0.507 | 0.4015 | No | ||
50 | BDKRB1 | 730592 | 3442 | 0.490 | 0.4023 | No | ||
51 | ELL | 3520731 | 3707 | 0.416 | 0.3905 | No | ||
52 | TUBB4 | 5310681 | 3797 | 0.395 | 0.3881 | No | ||
53 | PRX | 2260400 4200347 | 3935 | 0.365 | 0.3830 | No | ||
54 | PTPRR | 130121 3990273 | 3939 | 0.365 | 0.3851 | No | ||
55 | MRGPRF | 4780746 | 4064 | 0.341 | 0.3805 | No | ||
56 | SLC26A9 | 3440722 5340088 7510093 | 4156 | 0.324 | 0.3776 | No | ||
57 | RPS20 | 1740092 | 4185 | 0.320 | 0.3780 | No | ||
58 | HCN3 | 3940438 6840750 | 4223 | 0.314 | 0.3780 | No | ||
59 | RB1CC1 | 510494 7100072 | 4312 | 0.298 | 0.3750 | No | ||
60 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 4342 | 0.293 | 0.3753 | No | ||
61 | DYSF | 4670411 | 4476 | 0.272 | 0.3698 | No | ||
62 | ITGB4 | 1740021 3840482 | 4518 | 0.265 | 0.3692 | No | ||
63 | PROK2 | 540538 | 4755 | 0.235 | 0.3578 | No | ||
64 | HOXB3 | 520292 | 4764 | 0.234 | 0.3589 | No | ||
65 | CSMD3 | 1660427 1940687 | 5010 | 0.206 | 0.3468 | No | ||
66 | PIM1 | 630047 | 5122 | 0.191 | 0.3420 | No | ||
67 | PADI3 | 6520072 | 5249 | 0.179 | 0.3363 | No | ||
68 | GKN1 | 5420091 | 5261 | 0.178 | 0.3368 | No | ||
69 | F2RL2 | 6110736 | 5353 | 0.170 | 0.3329 | No | ||
70 | HS3ST3B1 | 380040 | 5372 | 0.169 | 0.3330 | No | ||
71 | ELAVL2 | 360181 | 5502 | 0.159 | 0.3270 | No | ||
72 | DIRAS1 | 2640270 | 5624 | 0.150 | 0.3213 | No | ||
73 | SYN1 | 4920301 7050440 | 5774 | 0.139 | 0.3141 | No | ||
74 | OSBP | 5390471 | 5823 | 0.136 | 0.3123 | No | ||
75 | EEF1A2 | 2260162 5290086 | 5865 | 0.134 | 0.3110 | No | ||
76 | PSME4 | 380348 1770131 | 5960 | 0.126 | 0.3066 | No | ||
77 | SYP | 2690168 | 6245 | 0.111 | 0.2919 | No | ||
78 | BMP2 | 6620687 | 6357 | 0.104 | 0.2865 | No | ||
79 | LRRC15 | 3940609 | 6540 | 0.096 | 0.2773 | No | ||
80 | GDNF | 4050487 5720739 | 6571 | 0.094 | 0.2762 | No | ||
81 | VIT | 6620301 | 6857 | 0.083 | 0.2613 | No | ||
82 | TLL1 | 2680315 | 6920 | 0.081 | 0.2584 | No | ||
83 | GPR3 | 2970452 | 7007 | 0.077 | 0.2542 | No | ||
84 | FGF12 | 1740446 2360037 | 7431 | 0.064 | 0.2317 | No | ||
85 | LRRTM3 | 4210021 | 7581 | 0.060 | 0.2239 | No | ||
86 | TRIB1 | 2320435 | 7647 | 0.058 | 0.2208 | No | ||
87 | CAPN6 | 1740168 | 7693 | 0.057 | 0.2187 | No | ||
88 | FOXN1 | 4730075 | 7704 | 0.057 | 0.2185 | No | ||
89 | TGM3 | 840576 | 7730 | 0.056 | 0.2175 | No | ||
90 | EIF3S1 | 6130368 6770044 | 7791 | 0.055 | 0.2146 | No | ||
91 | MYH14 | 4010017 | 7821 | 0.055 | 0.2133 | No | ||
92 | DNAJC5B | 60368 | 7838 | 0.054 | 0.2128 | No | ||
93 | COL7A1 | 1230168 2190072 | 7886 | 0.053 | 0.2106 | No | ||
94 | ELK3 | 460377 1400762 3710497 | 8145 | 0.047 | 0.1969 | No | ||
95 | LY6G6C | 6020673 | 8238 | 0.045 | 0.1922 | No | ||
96 | FABP4 | 5050114 | 8498 | 0.039 | 0.1784 | No | ||
97 | TAC1 | 7000195 380706 | 8632 | 0.037 | 0.1714 | No | ||
98 | SLC24A4 | 2100487 | 8653 | 0.036 | 0.1705 | No | ||
99 | TIAL1 | 4150048 6510605 | 8663 | 0.036 | 0.1702 | No | ||
100 | GFAP | 2060092 | 8686 | 0.035 | 0.1693 | No | ||
101 | LPP | 1660541 | 8726 | 0.034 | 0.1674 | No | ||
102 | FOXA1 | 3710609 | 8791 | 0.033 | 0.1641 | No | ||
103 | GPR56 | 1190494 | 8795 | 0.033 | 0.1641 | No | ||
104 | NTN4 | 6940398 | 8865 | 0.031 | 0.1606 | No | ||
105 | FADS3 | 3120079 | 8948 | 0.030 | 0.1563 | No | ||
106 | DSC2 | 840484 | 9021 | 0.028 | 0.1526 | No | ||
107 | P2RXL1 | 4730390 5220446 | 9139 | 0.026 | 0.1464 | No | ||
108 | PSMD11 | 2340538 6510053 | 9169 | 0.025 | 0.1450 | No | ||
109 | CSF3 | 2230193 6660707 | 9341 | 0.022 | 0.1358 | No | ||
110 | MYBPH | 2190711 | 9350 | 0.022 | 0.1356 | No | ||
111 | GRIA1 | 1340152 3780750 4920440 | 9369 | 0.022 | 0.1347 | No | ||
112 | TREX1 | 3450040 7100692 | 9505 | 0.020 | 0.1275 | No | ||
113 | TNXB | 630592 3830020 5360497 7000673 | 9668 | 0.017 | 0.1188 | No | ||
114 | ENO2 | 2320068 | 9796 | 0.015 | 0.1120 | No | ||
115 | SYT2 | 60609 | 9843 | 0.014 | 0.1096 | No | ||
116 | BNIP3 | 3140270 | 10417 | 0.004 | 0.0785 | No | ||
117 | SHC3 | 2690398 | 10481 | 0.003 | 0.0751 | No | ||
118 | IL1RN | 2370333 | 10595 | 0.001 | 0.0690 | No | ||
119 | PHLDA2 | 4810494 | 10607 | 0.001 | 0.0684 | No | ||
120 | IL11 | 1740398 | 10880 | -0.003 | 0.0537 | No | ||
121 | NR1I3 | 50026 1240673 | 11110 | -0.007 | 0.0413 | No | ||
122 | CFL2 | 380239 6200368 | 11203 | -0.009 | 0.0364 | No | ||
123 | SH3RF2 | 6200600 | 11409 | -0.013 | 0.0253 | No | ||
124 | SLC6A5 | 870121 | 11427 | -0.013 | 0.0245 | No | ||
125 | UCN2 | 4590372 | 11917 | -0.023 | -0.0019 | No | ||
126 | LAMB3 | 7100301 | 11925 | -0.023 | -0.0022 | No | ||
127 | FAP | 4560019 | 12262 | -0.030 | -0.0202 | No | ||
128 | TRIM47 | 5080717 | 12388 | -0.033 | -0.0268 | No | ||
129 | MYB | 1660494 5860451 6130706 | 12609 | -0.039 | -0.0385 | No | ||
130 | MAMDC2 | 430471 | 12690 | -0.041 | -0.0426 | No | ||
131 | SYNGR1 | 5130452 6650056 | 12879 | -0.047 | -0.0525 | No | ||
132 | AKAP1 | 110148 1740735 2260019 7000563 | 13064 | -0.053 | -0.0621 | No | ||
133 | SNCB | 3360133 | 13189 | -0.057 | -0.0685 | No | ||
134 | SPARC | 1690086 | 13261 | -0.060 | -0.0720 | No | ||
135 | GNAI1 | 4560390 | 13389 | -0.065 | -0.0784 | No | ||
136 | SLC26A1 | 2190142 | 13573 | -0.075 | -0.0879 | No | ||
137 | MMP3 | 2650368 2970056 | 13915 | -0.096 | -0.1058 | No | ||
138 | AKT3 | 1580270 3290278 | 13982 | -0.102 | -0.1088 | No | ||
139 | LAMC2 | 450692 2680041 4200059 4670148 | 13987 | -0.102 | -0.1083 | No | ||
140 | KCNA2 | 5080403 | 14027 | -0.105 | -0.1098 | No | ||
141 | MARK1 | 450484 | 14055 | -0.108 | -0.1106 | No | ||
142 | WASF2 | 4850592 | 14136 | -0.115 | -0.1142 | No | ||
143 | NRAS | 6900577 | 14288 | -0.132 | -0.1216 | No | ||
144 | SSH2 | 360056 | 14301 | -0.133 | -0.1214 | No | ||
145 | ADAMTSL1 | 2970092 | 14424 | -0.148 | -0.1271 | No | ||
146 | IBRDC2 | 5130041 | 14449 | -0.152 | -0.1275 | No | ||
147 | RGS2 | 1090736 | 14637 | -0.182 | -0.1365 | No | ||
148 | LAMA3 | 1190131 5290239 | 14647 | -0.184 | -0.1359 | No | ||
149 | AXUD1 | 1230053 | 14764 | -0.207 | -0.1409 | No | ||
150 | NEK6 | 3360687 | 14798 | -0.213 | -0.1413 | No | ||
151 | CAPN12 | 2100050 | 14865 | -0.227 | -0.1435 | No | ||
152 | CDKN1A | 4050088 6400706 | 14886 | -0.231 | -0.1431 | No | ||
153 | EIF4E | 1580403 70133 6380215 | 15012 | -0.264 | -0.1483 | No | ||
154 | EN1 | 5360168 7050025 | 15069 | -0.281 | -0.1496 | No | ||
155 | NLK | 2030010 2450041 | 15117 | -0.295 | -0.1503 | No | ||
156 | MPV17 | 1190133 4070427 4570577 | 15326 | -0.358 | -0.1594 | No | ||
157 | ABI3 | 1740563 | 15578 | -0.448 | -0.1702 | No | ||
158 | SEC24D | 3060279 | 15613 | -0.462 | -0.1692 | No | ||
159 | PSMD4 | 430068 | 15691 | -0.488 | -0.1703 | No | ||
160 | MAST2 | 6200348 | 15711 | -0.496 | -0.1683 | No | ||
161 | RIN1 | 510593 | 15763 | -0.520 | -0.1678 | No | ||
162 | RAB34 | 770411 | 15808 | -0.537 | -0.1669 | No | ||
163 | GTPBP2 | 2760750 | 15986 | -0.618 | -0.1726 | No | ||
164 | TNRC15 | 6760746 | 16090 | -0.662 | -0.1741 | No | ||
165 | ACADVL | 6040403 | 16257 | -0.760 | -0.1784 | No | ||
166 | DYRK1A | 3190181 | 16263 | -0.763 | -0.1739 | No | ||
167 | GPX1 | 4150093 | 16271 | -0.768 | -0.1695 | No | ||
168 | APOBEC1 | 4610022 | 16329 | -0.801 | -0.1676 | No | ||
169 | GTF2B | 6860685 | 16353 | -0.810 | -0.1638 | No | ||
170 | LAMC1 | 4730025 | 16521 | -0.908 | -0.1673 | No | ||
171 | TRAF3 | 5690647 | 16573 | -0.943 | -0.1642 | No | ||
172 | SGK | 1400131 2480056 | 16716 | -1.013 | -0.1656 | No | ||
173 | BTK | 3130044 | 16802 | -1.068 | -0.1636 | No | ||
174 | MECP2 | 1940450 | 16813 | -1.075 | -0.1574 | No | ||
175 | EMP3 | 1500722 1570039 | 17068 | -1.293 | -0.1632 | No | ||
176 | RBBP7 | 430113 450450 2370309 | 17109 | -1.334 | -0.1571 | No | ||
177 | PSMD12 | 730044 | 17438 | -1.690 | -0.1644 | No | ||
178 | CHST1 | 50601 | 17721 | -2.056 | -0.1669 | No | ||
179 | RPL23A | 1450403 | 17850 | -2.220 | -0.1600 | No | ||
180 | PSMD7 | 2030619 6220594 | 17919 | -2.328 | -0.1493 | No | ||
181 | NR1D1 | 2360471 770746 6590204 | 18014 | -2.480 | -0.1389 | No | ||
182 | EIF4G1 | 4070446 | 18120 | -2.717 | -0.1278 | No | ||
183 | ATP1B1 | 3130594 | 18138 | -2.762 | -0.1115 | No | ||
184 | TRIM8 | 6130441 | 18163 | -2.806 | -0.0954 | No | ||
185 | BRD2 | 1450300 5340484 6100605 | 18220 | -2.955 | -0.0801 | No | ||
186 | LUC7L | 6040156 6110411 | 18294 | -3.137 | -0.0645 | No | ||
187 | PPP2CA | 3990113 | 18501 | -4.067 | -0.0504 | No | ||
188 | SRPK2 | 6380341 | 18529 | -4.282 | -0.0253 | No | ||
189 | H3F3B | 1410300 | 18574 | -4.822 | 0.0023 | No |