Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
Upregulated in class | truncNotch |
GeneSet | V$AP1_Q6 |
Enrichment Score (ES) | 0.42463169 |
Normalized Enrichment Score (NES) | 1.2389473 |
Nominal p-value | 0.041867957 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | ALDOA | 6290672 | 20 | 5.593 | 0.0396 | Yes | ||
2 | AKT1S1 | 1660048 | 200 | 3.525 | 0.0555 | Yes | ||
3 | MAPK3 | 580161 4780035 | 236 | 3.390 | 0.0782 | Yes | ||
4 | ABCD1 | 5670373 | 248 | 3.366 | 0.1021 | Yes | ||
5 | VAMP5 | 3830300 | 269 | 3.288 | 0.1249 | Yes | ||
6 | ABCA2 | 5050039 | 385 | 2.965 | 0.1402 | Yes | ||
7 | CAPNS1 | 3940113 | 443 | 2.827 | 0.1577 | Yes | ||
8 | ITPKC | 5420021 | 517 | 2.678 | 0.1732 | Yes | ||
9 | ETV5 | 110017 | 582 | 2.603 | 0.1886 | Yes | ||
10 | LMNA | 520471 1500075 3190167 4210020 | 594 | 2.565 | 0.2067 | Yes | ||
11 | ENO1 | 5340128 | 621 | 2.530 | 0.2237 | Yes | ||
12 | HDAC3 | 4060072 | 777 | 2.296 | 0.2320 | Yes | ||
13 | CAMKK1 | 6370324 | 784 | 2.283 | 0.2482 | Yes | ||
14 | TBC1D17 | 1780450 | 813 | 2.248 | 0.2630 | Yes | ||
15 | RAB3D | 4210253 | 915 | 2.109 | 0.2729 | Yes | ||
16 | PKP3 | 3710048 | 947 | 2.072 | 0.2863 | Yes | ||
17 | ROM1 | 3130685 | 978 | 2.044 | 0.2995 | Yes | ||
18 | ADCK4 | 1660180 | 1033 | 1.985 | 0.3110 | Yes | ||
19 | NCDN | 50040 1980739 3520603 | 1097 | 1.916 | 0.3215 | Yes | ||
20 | UBE2C | 6130017 | 1159 | 1.873 | 0.3318 | Yes | ||
21 | ABHD2 | 4850504 6840010 | 1270 | 1.761 | 0.3387 | Yes | ||
22 | DCTN2 | 540471 3780717 | 1404 | 1.640 | 0.3434 | Yes | ||
23 | TAGLN2 | 4560121 | 1433 | 1.619 | 0.3536 | Yes | ||
24 | TGFBR2 | 1780711 1980537 6550398 | 1564 | 1.525 | 0.3577 | Yes | ||
25 | UBQLN1 | 110280 730376 2470133 6590594 | 1668 | 1.469 | 0.3627 | Yes | ||
26 | ABHD4 | 6760450 | 1687 | 1.462 | 0.3724 | Yes | ||
27 | VASP | 7050500 | 1785 | 1.374 | 0.3771 | Yes | ||
28 | ECM1 | 940068 5390309 | 1812 | 1.342 | 0.3855 | Yes | ||
29 | SYTL1 | 510487 | 1933 | 1.252 | 0.3880 | Yes | ||
30 | RIT1 | 5390338 | 1999 | 1.206 | 0.3933 | Yes | ||
31 | PDGFRB | 6450279 | 2045 | 1.174 | 0.3994 | Yes | ||
32 | HSPB8 | 540563 | 2061 | 1.166 | 0.4070 | Yes | ||
33 | AP2A2 | 130082 | 2178 | 1.086 | 0.4086 | Yes | ||
34 | NDRG2 | 450403 | 2275 | 1.032 | 0.4109 | Yes | ||
35 | PADI4 | 1740075 4810441 | 2336 | 1.002 | 0.4150 | Yes | ||
36 | FHL3 | 1090369 2650017 | 2403 | 0.968 | 0.4184 | Yes | ||
37 | BAZ2A | 730184 | 2418 | 0.958 | 0.4246 | Yes | ||
38 | SCRN1 | 6040025 6580019 | 2727 | 0.786 | 0.4136 | No | ||
39 | TMEM24 | 5860039 | 2797 | 0.746 | 0.4153 | No | ||
40 | PSMD2 | 4670706 5050364 | 2859 | 0.711 | 0.4172 | No | ||
41 | NFRKB | 3130538 | 3044 | 0.632 | 0.4118 | No | ||
42 | ADORA2A | 1990687 | 3095 | 0.610 | 0.4135 | No | ||
43 | MDFI | 6200041 | 3273 | 0.546 | 0.4079 | No | ||
44 | DCN | 510332 5340026 5900711 6550092 | 3359 | 0.517 | 0.4070 | No | ||
45 | RTN4 | 50725 630647 870097 870184 | 3380 | 0.512 | 0.4097 | No | ||
46 | BLMH | 1410438 | 3464 | 0.483 | 0.4087 | No | ||
47 | VIM | 20431 | 3465 | 0.483 | 0.4122 | No | ||
48 | EPHA2 | 5890056 | 3762 | 0.403 | 0.3991 | No | ||
49 | CLSTN3 | 2350685 | 3794 | 0.396 | 0.4003 | No | ||
50 | PAPPA | 4230463 | 3954 | 0.361 | 0.3943 | No | ||
51 | GADD45A | 2900717 | 4034 | 0.346 | 0.3925 | No | ||
52 | RB1CC1 | 510494 7100072 | 4312 | 0.298 | 0.3796 | No | ||
53 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 4342 | 0.293 | 0.3802 | No | ||
54 | NRIP3 | 1340372 | 4705 | 0.240 | 0.3623 | No | ||
55 | HSPB7 | 1190441 | 4887 | 0.220 | 0.3541 | No | ||
56 | STAT5B | 6200026 | 4979 | 0.210 | 0.3507 | No | ||
57 | AXIN2 | 3850131 | 4989 | 0.208 | 0.3517 | No | ||
58 | FLNC | 2360048 5050270 | 5349 | 0.171 | 0.3334 | No | ||
59 | DIRAS1 | 2640270 | 5624 | 0.150 | 0.3197 | No | ||
60 | COBL | 2480452 6110066 | 5695 | 0.145 | 0.3169 | No | ||
61 | GGN | 1410528 4210082 5290170 | 5736 | 0.142 | 0.3158 | No | ||
62 | EEF1A2 | 2260162 5290086 | 5865 | 0.134 | 0.3098 | No | ||
63 | PSME4 | 380348 1770131 | 5960 | 0.126 | 0.3056 | No | ||
64 | PVALB | 5570450 | 5970 | 0.126 | 0.3061 | No | ||
65 | STX17 | 2260037 | 6012 | 0.123 | 0.3047 | No | ||
66 | ELA1 | 3390167 | 6023 | 0.122 | 0.3051 | No | ||
67 | ST18 | 5720537 | 6045 | 0.121 | 0.3048 | No | ||
68 | MAP1A | 4920576 | 6187 | 0.114 | 0.2980 | No | ||
69 | BMP2 | 6620687 | 6357 | 0.104 | 0.2896 | No | ||
70 | MMP9 | 580338 | 6541 | 0.096 | 0.2804 | No | ||
71 | MMP7 | 1780497 | 6700 | 0.089 | 0.2724 | No | ||
72 | RIMS1 | 5670022 | 6724 | 0.088 | 0.2718 | No | ||
73 | SFN | 6290301 7510608 | 6744 | 0.087 | 0.2714 | No | ||
74 | PTPRH | 3870070 | 6865 | 0.083 | 0.2655 | No | ||
75 | IL23A | 6290044 | 6873 | 0.082 | 0.2657 | No | ||
76 | TLL1 | 2680315 | 6920 | 0.081 | 0.2638 | No | ||
77 | GPR3 | 2970452 | 7007 | 0.077 | 0.2597 | No | ||
78 | AK5 | 6290348 | 7017 | 0.077 | 0.2598 | No | ||
79 | OLR1 | 50025 3840484 | 7141 | 0.073 | 0.2537 | No | ||
80 | FGF12 | 1740446 2360037 | 7431 | 0.064 | 0.2384 | No | ||
81 | DHRS3 | 360609 | 7456 | 0.063 | 0.2376 | No | ||
82 | SCEL | 3190129 | 7641 | 0.058 | 0.2280 | No | ||
83 | TRIB1 | 2320435 | 7647 | 0.058 | 0.2282 | No | ||
84 | EIF3S1 | 6130368 6770044 | 7791 | 0.055 | 0.2208 | No | ||
85 | ELK3 | 460377 1400762 3710497 | 8145 | 0.047 | 0.2020 | No | ||
86 | KBTBD5 | 6350025 | 8317 | 0.043 | 0.1931 | No | ||
87 | NR0B2 | 2470692 | 8355 | 0.042 | 0.1913 | No | ||
88 | SPATS2 | 2360066 | 8545 | 0.039 | 0.1814 | No | ||
89 | TIAL1 | 4150048 6510605 | 8663 | 0.036 | 0.1753 | No | ||
90 | GFAP | 2060092 | 8686 | 0.035 | 0.1744 | No | ||
91 | LPP | 1660541 | 8726 | 0.034 | 0.1725 | No | ||
92 | WDFY3 | 3610041 4560333 4570273 | 8747 | 0.034 | 0.1716 | No | ||
93 | GAB2 | 1410280 2340520 4280040 | 8801 | 0.033 | 0.1690 | No | ||
94 | GJB3 | 2650040 | 8930 | 0.030 | 0.1623 | No | ||
95 | PRDM1 | 3170347 3520301 | 8950 | 0.030 | 0.1615 | No | ||
96 | P2RXL1 | 4730390 5220446 | 9139 | 0.026 | 0.1515 | No | ||
97 | IGSF9 | 1770411 | 9167 | 0.025 | 0.1502 | No | ||
98 | PSMD11 | 2340538 6510053 | 9169 | 0.025 | 0.1503 | No | ||
99 | MYBPH | 2190711 | 9350 | 0.022 | 0.1407 | No | ||
100 | SFTPC | 3290133 | 9407 | 0.021 | 0.1378 | No | ||
101 | C3AR1 | 5720131 | 9560 | 0.019 | 0.1297 | No | ||
102 | ANXA7 | 6110446 | 9595 | 0.018 | 0.1280 | No | ||
103 | S100A5 | 4120592 | 9756 | 0.015 | 0.1194 | No | ||
104 | FBXW11 | 6450632 | 9778 | 0.015 | 0.1184 | No | ||
105 | SYT2 | 60609 | 9843 | 0.014 | 0.1150 | No | ||
106 | UCHL3 | 1240735 | 9919 | 0.012 | 0.1111 | No | ||
107 | HOXA11 | 6980133 | 10253 | 0.007 | 0.0930 | No | ||
108 | CRYBA2 | 5900138 | 10452 | 0.003 | 0.0823 | No | ||
109 | SHC3 | 2690398 | 10481 | 0.003 | 0.0808 | No | ||
110 | AP2B1 | 1450184 2370148 3520139 4850593 | 10505 | 0.003 | 0.0796 | No | ||
111 | IL1RN | 2370333 | 10595 | 0.001 | 0.0748 | No | ||
112 | PHLDA2 | 4810494 | 10607 | 0.001 | 0.0742 | No | ||
113 | TRPV3 | 540341 | 10957 | -0.005 | 0.0553 | No | ||
114 | EFNA1 | 3840672 | 11083 | -0.007 | 0.0486 | No | ||
115 | DSTN | 3140592 | 11144 | -0.008 | 0.0454 | No | ||
116 | IL9 | 3440338 | 11165 | -0.008 | 0.0443 | No | ||
117 | USP13 | 1450670 | 11797 | -0.020 | 0.0102 | No | ||
118 | SLC35E4 | 2370711 | 11810 | -0.020 | 0.0097 | No | ||
119 | UCN2 | 4590372 | 11917 | -0.023 | 0.0042 | No | ||
120 | OMG | 6760066 | 11946 | -0.023 | 0.0028 | No | ||
121 | FAP | 4560019 | 12262 | -0.030 | -0.0141 | No | ||
122 | HOXD3 | 6450154 | 12268 | -0.030 | -0.0141 | No | ||
123 | PLCD1 | 2030484 | 12794 | -0.044 | -0.0423 | No | ||
124 | PTPRN | 5900577 | 12891 | -0.048 | -0.0471 | No | ||
125 | XLKD1 | 520441 | 13054 | -0.053 | -0.0555 | No | ||
126 | SNCB | 3360133 | 13189 | -0.057 | -0.0624 | No | ||
127 | SPARC | 1690086 | 13261 | -0.060 | -0.0658 | No | ||
128 | GNAI1 | 4560390 | 13389 | -0.065 | -0.0722 | No | ||
129 | DSCR1L1 | 940438 | 13434 | -0.067 | -0.0741 | No | ||
130 | SLC26A1 | 2190142 | 13573 | -0.075 | -0.0811 | No | ||
131 | PFTK1 | 1780181 | 13767 | -0.086 | -0.0909 | No | ||
132 | LAMC2 | 450692 2680041 4200059 4670148 | 13987 | -0.102 | -0.1020 | No | ||
133 | KCNA2 | 5080403 | 14027 | -0.105 | -0.1034 | No | ||
134 | MARK1 | 450484 | 14055 | -0.108 | -0.1041 | No | ||
135 | NFATC4 | 2470735 | 14059 | -0.108 | -0.1034 | No | ||
136 | PCDH9 | 2100136 | 14245 | -0.126 | -0.1126 | No | ||
137 | PTP4A1 | 130692 | 14273 | -0.130 | -0.1131 | No | ||
138 | IBRDC2 | 5130041 | 14449 | -0.152 | -0.1215 | No | ||
139 | IDS | 360619 5720161 | 14465 | -0.153 | -0.1212 | No | ||
140 | LAPTM5 | 5550372 | 14586 | -0.172 | -0.1264 | No | ||
141 | DTNA | 1340600 1780731 2340278 2850132 | 14597 | -0.174 | -0.1257 | No | ||
142 | LAMA3 | 1190131 5290239 | 14647 | -0.184 | -0.1270 | No | ||
143 | PITPNC1 | 3990017 | 14748 | -0.205 | -0.1310 | No | ||
144 | COL27A1 | 1740390 | 14752 | -0.205 | -0.1296 | No | ||
145 | NEK6 | 3360687 | 14798 | -0.213 | -0.1305 | No | ||
146 | CDKN1A | 4050088 6400706 | 14886 | -0.231 | -0.1336 | No | ||
147 | APBA2BP | 5700341 | 14997 | -0.259 | -0.1377 | No | ||
148 | EIF4E | 1580403 70133 6380215 | 15012 | -0.264 | -0.1365 | No | ||
149 | CASK | 2340215 3290576 6770215 | 15035 | -0.271 | -0.1357 | No | ||
150 | ROCK2 | 1780035 5720025 | 15118 | -0.295 | -0.1380 | No | ||
151 | PEA15 | 4590685 | 15176 | -0.313 | -0.1388 | No | ||
152 | VDR | 130156 510438 | 15287 | -0.348 | -0.1423 | No | ||
153 | LTBP3 | 1190162 2650440 6520451 | 15318 | -0.354 | -0.1413 | No | ||
154 | LRRFIP2 | 670575 730152 6590438 | 15327 | -0.359 | -0.1392 | No | ||
155 | MCART1 | 5270059 | 15436 | -0.397 | -0.1421 | No | ||
156 | SCOC | 610048 2230053 | 15517 | -0.427 | -0.1434 | No | ||
157 | ABI3 | 1740563 | 15578 | -0.448 | -0.1434 | No | ||
158 | PSMD4 | 430068 | 15691 | -0.488 | -0.1459 | No | ||
159 | RIN1 | 510593 | 15763 | -0.520 | -0.1460 | No | ||
160 | CMAS | 2190129 | 16136 | -0.688 | -0.1611 | No | ||
161 | GPX1 | 4150093 | 16271 | -0.768 | -0.1628 | No | ||
162 | APOBEC1 | 4610022 | 16329 | -0.801 | -0.1601 | No | ||
163 | GTF2B | 6860685 | 16353 | -0.810 | -0.1555 | No | ||
164 | PKN3 | 2260538 | 16367 | -0.816 | -0.1502 | No | ||
165 | POLR3E | 380152 | 16447 | -0.869 | -0.1482 | No | ||
166 | LAMC1 | 4730025 | 16521 | -0.908 | -0.1456 | No | ||
167 | TRAF3 | 5690647 | 16573 | -0.943 | -0.1415 | No | ||
168 | SLC16A6 | 1690156 | 16751 | -1.035 | -0.1436 | No | ||
169 | WNT6 | 4570364 | 16778 | -1.055 | -0.1373 | No | ||
170 | BTK | 3130044 | 16802 | -1.068 | -0.1308 | No | ||
171 | YWHAZ | 1230717 | 17058 | -1.283 | -0.1353 | No | ||
172 | RBBP7 | 430113 450450 2370309 | 17109 | -1.334 | -0.1283 | No | ||
173 | TCF12 | 3610324 7000156 | 17340 | -1.578 | -0.1293 | No | ||
174 | PSMD12 | 730044 | 17438 | -1.690 | -0.1223 | No | ||
175 | PDAP1 | 1410735 | 17516 | -1.779 | -0.1135 | No | ||
176 | NEFH | 630239 | 17555 | -1.821 | -0.1024 | No | ||
177 | PSMD7 | 2030619 6220594 | 17919 | -2.328 | -0.1051 | No | ||
178 | CYFIP1 | 5690082 | 17952 | -2.374 | -0.0896 | No | ||
179 | NR1D1 | 2360471 770746 6590204 | 18014 | -2.480 | -0.0749 | No | ||
180 | ICK | 1580746 3140021 | 18048 | -2.543 | -0.0582 | No | ||
181 | XPOT | 7050184 | 18063 | -2.580 | -0.0402 | No | ||
182 | ATP1B1 | 3130594 | 18138 | -2.762 | -0.0241 | No | ||
183 | TRIM8 | 6130441 | 18163 | -2.806 | -0.0050 | No | ||
184 | PPP2CA | 3990113 | 18501 | -4.067 | 0.0062 | No |