Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
Upregulated in class | truncNotch |
GeneSet | V$AP1_Q4 |
Enrichment Score (ES) | 0.43273672 |
Normalized Enrichment Score (NES) | 1.2526432 |
Nominal p-value | 0.055743244 |
FDR q-value | 0.96232814 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | RPL27A | 3130451 110195 6840494 | 17 | 5.709 | 0.0413 | Yes | ||
2 | GNGT2 | 540176 | 50 | 4.702 | 0.0744 | Yes | ||
3 | ABCB6 | 6350138 | 135 | 3.862 | 0.0984 | Yes | ||
4 | LIMK1 | 5080064 | 164 | 3.660 | 0.1240 | Yes | ||
5 | AKT1S1 | 1660048 | 200 | 3.525 | 0.1481 | Yes | ||
6 | MAPK3 | 580161 4780035 | 236 | 3.390 | 0.1713 | Yes | ||
7 | CD151 | 1450592 3780309 | 347 | 3.071 | 0.1881 | Yes | ||
8 | CAPNS1 | 3940113 | 443 | 2.827 | 0.2038 | Yes | ||
9 | ETV5 | 110017 | 582 | 2.603 | 0.2156 | Yes | ||
10 | LMNA | 520471 1500075 3190167 4210020 | 594 | 2.565 | 0.2340 | Yes | ||
11 | PPP1R9B | 3130619 | 599 | 2.558 | 0.2527 | Yes | ||
12 | KCNN4 | 2680129 | 607 | 2.550 | 0.2712 | Yes | ||
13 | HDAC3 | 4060072 | 777 | 2.296 | 0.2790 | Yes | ||
14 | CAMKK1 | 6370324 | 784 | 2.283 | 0.2956 | Yes | ||
15 | TBC1D17 | 1780450 | 813 | 2.248 | 0.3107 | Yes | ||
16 | ROM1 | 3130685 | 978 | 2.044 | 0.3169 | Yes | ||
17 | UBE2C | 6130017 | 1159 | 1.873 | 0.3210 | Yes | ||
18 | ABHD2 | 4850504 6840010 | 1270 | 1.761 | 0.3281 | Yes | ||
19 | TNFRSF12A | 4810253 | 1329 | 1.716 | 0.3376 | Yes | ||
20 | DCTN2 | 540471 3780717 | 1404 | 1.640 | 0.3457 | Yes | ||
21 | TAGLN2 | 4560121 | 1433 | 1.619 | 0.3562 | Yes | ||
22 | BAG2 | 2900324 | 1539 | 1.540 | 0.3619 | Yes | ||
23 | TGFBR2 | 1780711 1980537 6550398 | 1564 | 1.525 | 0.3719 | Yes | ||
24 | UBQLN1 | 110280 730376 2470133 6590594 | 1668 | 1.469 | 0.3772 | Yes | ||
25 | ABHD4 | 6760450 | 1687 | 1.462 | 0.3870 | Yes | ||
26 | CIZ1 | 4150128 6130484 | 1747 | 1.413 | 0.3943 | Yes | ||
27 | SYTL1 | 510487 | 1933 | 1.252 | 0.3935 | Yes | ||
28 | PDGFRB | 6450279 | 2045 | 1.174 | 0.3961 | Yes | ||
29 | ISG20 | 1770750 | 2147 | 1.105 | 0.3988 | Yes | ||
30 | STOML2 | 1940487 | 2177 | 1.086 | 0.4053 | Yes | ||
31 | AP2A2 | 130082 | 2178 | 1.086 | 0.4133 | Yes | ||
32 | FKBP8 | 4060019 | 2368 | 0.987 | 0.4104 | Yes | ||
33 | FHL3 | 1090369 2650017 | 2403 | 0.968 | 0.4157 | Yes | ||
34 | BAZ2A | 730184 | 2418 | 0.958 | 0.4220 | Yes | ||
35 | DTX2 | 4210041 7000008 | 2426 | 0.950 | 0.4287 | Yes | ||
36 | IGFBP6 | 1580181 | 2478 | 0.921 | 0.4327 | Yes | ||
37 | EEF1A1 | 1980193 1990195 4670735 | 2634 | 0.835 | 0.4305 | No | ||
38 | SCRN1 | 6040025 6580019 | 2727 | 0.786 | 0.4313 | No | ||
39 | MMP19 | 5080377 | 2842 | 0.722 | 0.4305 | No | ||
40 | NFRKB | 3130538 | 3044 | 0.632 | 0.4243 | No | ||
41 | ADORA2A | 1990687 | 3095 | 0.610 | 0.4261 | No | ||
42 | MDFI | 6200041 | 3273 | 0.546 | 0.4205 | No | ||
43 | RTN4 | 50725 630647 870097 870184 | 3380 | 0.512 | 0.4185 | No | ||
44 | DUSP13 | 6400152 | 3397 | 0.508 | 0.4214 | No | ||
45 | BLMH | 1410438 | 3464 | 0.483 | 0.4214 | No | ||
46 | VIM | 20431 | 3465 | 0.483 | 0.4250 | No | ||
47 | EPHA2 | 5890056 | 3762 | 0.403 | 0.4119 | No | ||
48 | CLSTN3 | 2350685 | 3794 | 0.396 | 0.4132 | No | ||
49 | ARRDC4 | 2810019 | 3841 | 0.387 | 0.4135 | No | ||
50 | PTPRR | 130121 3990273 | 3939 | 0.365 | 0.4110 | No | ||
51 | PAPPA | 4230463 | 3954 | 0.361 | 0.4129 | No | ||
52 | RB1CC1 | 510494 7100072 | 4312 | 0.298 | 0.3957 | No | ||
53 | IRAK1 | 4120593 | 4606 | 0.252 | 0.3817 | No | ||
54 | APOB48R | 2810070 | 4629 | 0.250 | 0.3823 | No | ||
55 | NRIP3 | 1340372 | 4705 | 0.240 | 0.3800 | No | ||
56 | HSPB7 | 1190441 | 4887 | 0.220 | 0.3718 | No | ||
57 | STAT5B | 6200026 | 4979 | 0.210 | 0.3685 | No | ||
58 | AXIN2 | 3850131 | 4989 | 0.208 | 0.3695 | No | ||
59 | CORO1C | 4570397 | 5174 | 0.186 | 0.3609 | No | ||
60 | PADI3 | 6520072 | 5249 | 0.179 | 0.3582 | No | ||
61 | GSN | 3830168 | 5267 | 0.177 | 0.3586 | No | ||
62 | HS3ST3B1 | 380040 | 5372 | 0.169 | 0.3542 | No | ||
63 | CCL22 | 6380086 | 5591 | 0.153 | 0.3435 | No | ||
64 | GGN | 1410528 4210082 5290170 | 5736 | 0.142 | 0.3367 | No | ||
65 | EEF1A2 | 2260162 5290086 | 5865 | 0.134 | 0.3308 | No | ||
66 | GPR150 | 2570440 | 5889 | 0.131 | 0.3305 | No | ||
67 | STX17 | 2260037 | 6012 | 0.123 | 0.3248 | No | ||
68 | ELA1 | 3390167 | 6023 | 0.122 | 0.3252 | No | ||
69 | ST18 | 5720537 | 6045 | 0.121 | 0.3249 | No | ||
70 | MAP1A | 4920576 | 6187 | 0.114 | 0.3181 | No | ||
71 | BMP2 | 6620687 | 6357 | 0.104 | 0.3097 | No | ||
72 | LRRC15 | 3940609 | 6540 | 0.096 | 0.3005 | No | ||
73 | MMP9 | 580338 | 6541 | 0.096 | 0.3013 | No | ||
74 | LRP1B | 1450193 | 6572 | 0.094 | 0.3003 | No | ||
75 | ESRRB | 3870082 | 6614 | 0.092 | 0.2988 | No | ||
76 | MMP7 | 1780497 | 6700 | 0.089 | 0.2948 | No | ||
77 | SFN | 6290301 7510608 | 6744 | 0.087 | 0.2931 | No | ||
78 | PTPRH | 3870070 | 6865 | 0.083 | 0.2872 | No | ||
79 | IL23A | 6290044 | 6873 | 0.082 | 0.2875 | No | ||
80 | LIFR | 3360068 3830102 | 6909 | 0.081 | 0.2862 | No | ||
81 | GPR3 | 2970452 | 7007 | 0.077 | 0.2815 | No | ||
82 | AK5 | 6290348 | 7017 | 0.077 | 0.2816 | No | ||
83 | DNM1 | 1660097 5340519 | 7087 | 0.075 | 0.2784 | No | ||
84 | ZIC1 | 670113 | 7333 | 0.067 | 0.2656 | No | ||
85 | FGF12 | 1740446 2360037 | 7431 | 0.064 | 0.2608 | No | ||
86 | TRIB1 | 2320435 | 7647 | 0.058 | 0.2496 | No | ||
87 | EIF3S1 | 6130368 6770044 | 7791 | 0.055 | 0.2422 | No | ||
88 | FGF11 | 840292 | 7997 | 0.050 | 0.2315 | No | ||
89 | ELK3 | 460377 1400762 3710497 | 8145 | 0.047 | 0.2238 | No | ||
90 | KBTBD5 | 6350025 | 8317 | 0.043 | 0.2149 | No | ||
91 | TIAL1 | 4150048 6510605 | 8663 | 0.036 | 0.1964 | No | ||
92 | LPP | 1660541 | 8726 | 0.034 | 0.1933 | No | ||
93 | WDFY3 | 3610041 4560333 4570273 | 8747 | 0.034 | 0.1925 | No | ||
94 | EYA1 | 1450278 5220390 | 8781 | 0.033 | 0.1909 | No | ||
95 | GAB2 | 1410280 2340520 4280040 | 8801 | 0.033 | 0.1901 | No | ||
96 | GJB3 | 2650040 | 8930 | 0.030 | 0.1834 | No | ||
97 | PRDM1 | 3170347 3520301 | 8950 | 0.030 | 0.1826 | No | ||
98 | PSMD11 | 2340538 6510053 | 9169 | 0.025 | 0.1710 | No | ||
99 | MYBPH | 2190711 | 9350 | 0.022 | 0.1614 | No | ||
100 | PSMA3 | 5900047 7040161 | 9538 | 0.019 | 0.1514 | No | ||
101 | ANXA7 | 6110446 | 9595 | 0.018 | 0.1484 | No | ||
102 | S100A5 | 4120592 | 9756 | 0.015 | 0.1399 | No | ||
103 | FBXW11 | 6450632 | 9778 | 0.015 | 0.1388 | No | ||
104 | EDN1 | 1770047 | 9867 | 0.013 | 0.1342 | No | ||
105 | UCHL3 | 1240735 | 9919 | 0.012 | 0.1315 | No | ||
106 | HOXA11 | 6980133 | 10253 | 0.007 | 0.1135 | No | ||
107 | PLAC1 | 2350594 | 10291 | 0.006 | 0.1115 | No | ||
108 | BNIP3 | 3140270 | 10417 | 0.004 | 0.1048 | No | ||
109 | CRYBA2 | 5900138 | 10452 | 0.003 | 0.1030 | No | ||
110 | SHC3 | 2690398 | 10481 | 0.003 | 0.1015 | No | ||
111 | AP2B1 | 1450184 2370148 3520139 4850593 | 10505 | 0.003 | 0.1002 | No | ||
112 | IL1RN | 2370333 | 10595 | 0.001 | 0.0954 | No | ||
113 | MAPRE3 | 7050504 | 10649 | 0.000 | 0.0925 | No | ||
114 | TRPV3 | 540341 | 10957 | -0.005 | 0.0759 | No | ||
115 | EFNA1 | 3840672 | 11083 | -0.007 | 0.0692 | No | ||
116 | DSTN | 3140592 | 11144 | -0.008 | 0.0660 | No | ||
117 | PAX9 | 3850519 | 11160 | -0.008 | 0.0652 | No | ||
118 | IL9 | 3440338 | 11165 | -0.008 | 0.0651 | No | ||
119 | ZIC4 | 1500082 | 11366 | -0.012 | 0.0543 | No | ||
120 | SH3RF2 | 6200600 | 11409 | -0.013 | 0.0521 | No | ||
121 | USP13 | 1450670 | 11797 | -0.020 | 0.0313 | No | ||
122 | UCN2 | 4590372 | 11917 | -0.023 | 0.0250 | No | ||
123 | LAMB3 | 7100301 | 11925 | -0.023 | 0.0248 | No | ||
124 | FAP | 4560019 | 12262 | -0.030 | 0.0068 | No | ||
125 | HOXD3 | 6450154 | 12268 | -0.030 | 0.0067 | No | ||
126 | GOLGA4 | 460300 | 12800 | -0.045 | -0.0218 | No | ||
127 | PTPRN | 5900577 | 12891 | -0.048 | -0.0263 | No | ||
128 | XLKD1 | 520441 | 13054 | -0.053 | -0.0347 | No | ||
129 | AKAP1 | 110148 1740735 2260019 7000563 | 13064 | -0.053 | -0.0348 | No | ||
130 | RAD23B | 2190671 | 13382 | -0.065 | -0.0515 | No | ||
131 | GNAI1 | 4560390 | 13389 | -0.065 | -0.0513 | No | ||
132 | IL6 | 380133 | 13663 | -0.080 | -0.0656 | No | ||
133 | UBE3A | 1240152 2690438 5860609 | 13746 | -0.084 | -0.0694 | No | ||
134 | CMYA1 | 6900632 | 13891 | -0.095 | -0.0765 | No | ||
135 | AKT3 | 1580270 3290278 | 13982 | -0.102 | -0.0806 | No | ||
136 | LAMC2 | 450692 2680041 4200059 4670148 | 13987 | -0.102 | -0.0801 | No | ||
137 | PCDH9 | 2100136 | 14245 | -0.126 | -0.0931 | No | ||
138 | NRAS | 6900577 | 14288 | -0.132 | -0.0944 | No | ||
139 | USP2 | 1190292 1240253 4850035 | 14344 | -0.138 | -0.0964 | No | ||
140 | CREM | 840156 6380438 6660041 6660168 | 14395 | -0.144 | -0.0980 | No | ||
141 | IBRDC2 | 5130041 | 14449 | -0.152 | -0.0998 | No | ||
142 | LAPTM5 | 5550372 | 14586 | -0.172 | -0.1059 | No | ||
143 | PITPNC1 | 3990017 | 14748 | -0.205 | -0.1131 | No | ||
144 | COL27A1 | 1740390 | 14752 | -0.205 | -0.1117 | No | ||
145 | EVI2B | 1050465 | 14755 | -0.206 | -0.1103 | No | ||
146 | NEK6 | 3360687 | 14798 | -0.213 | -0.1110 | No | ||
147 | PIM2 | 840136 5720692 7100577 | 14884 | -0.231 | -0.1139 | No | ||
148 | CDKN1A | 4050088 6400706 | 14886 | -0.231 | -0.1123 | No | ||
149 | RABEP1 | 4760427 6200463 | 14943 | -0.247 | -0.1135 | No | ||
150 | BACH1 | 290195 | 14954 | -0.249 | -0.1122 | No | ||
151 | APBA2BP | 5700341 | 14997 | -0.259 | -0.1125 | No | ||
152 | EIF4E | 1580403 70133 6380215 | 15012 | -0.264 | -0.1114 | No | ||
153 | CASK | 2340215 3290576 6770215 | 15035 | -0.271 | -0.1105 | No | ||
154 | ROCK2 | 1780035 5720025 | 15118 | -0.295 | -0.1128 | No | ||
155 | TCF7 | 3800736 5390181 | 15277 | -0.346 | -0.1188 | No | ||
156 | VDR | 130156 510438 | 15287 | -0.348 | -0.1167 | No | ||
157 | PDE4D | 2470528 6660014 | 15290 | -0.349 | -0.1143 | No | ||
158 | LTBP3 | 1190162 2650440 6520451 | 15318 | -0.354 | -0.1131 | No | ||
159 | LRRFIP2 | 670575 730152 6590438 | 15327 | -0.359 | -0.1109 | No | ||
160 | MCART1 | 5270059 | 15436 | -0.397 | -0.1138 | No | ||
161 | SCOC | 610048 2230053 | 15517 | -0.427 | -0.1150 | No | ||
162 | ABI3 | 1740563 | 15578 | -0.448 | -0.1149 | No | ||
163 | PSMD4 | 430068 | 15691 | -0.488 | -0.1174 | No | ||
164 | RIN1 | 510593 | 15763 | -0.520 | -0.1174 | No | ||
165 | MAP2K1 | 840739 | 16129 | -0.683 | -0.1321 | No | ||
166 | CMAS | 2190129 | 16136 | -0.688 | -0.1274 | No | ||
167 | APOBEC1 | 4610022 | 16329 | -0.801 | -0.1319 | No | ||
168 | PKN3 | 2260538 | 16367 | -0.816 | -0.1278 | No | ||
169 | IL10 | 2340685 2640541 2850403 6590286 | 16435 | -0.859 | -0.1251 | No | ||
170 | POLR3E | 380152 | 16447 | -0.869 | -0.1193 | No | ||
171 | LAMC1 | 4730025 | 16521 | -0.908 | -0.1165 | No | ||
172 | SLC16A6 | 1690156 | 16751 | -1.035 | -0.1213 | No | ||
173 | BTK | 3130044 | 16802 | -1.068 | -0.1161 | No | ||
174 | USP3 | 2060332 | 16935 | -1.162 | -0.1147 | No | ||
175 | RBBP7 | 430113 450450 2370309 | 17109 | -1.334 | -0.1142 | No | ||
176 | TCF12 | 3610324 7000156 | 17340 | -1.578 | -0.1150 | No | ||
177 | PDAP1 | 1410735 | 17516 | -1.779 | -0.1113 | No | ||
178 | KCNH2 | 1170451 | 17517 | -1.779 | -0.0982 | No | ||
179 | NEFH | 630239 | 17555 | -1.821 | -0.0867 | No | ||
180 | RPA3 | 5700136 | 17794 | -2.144 | -0.0837 | No | ||
181 | CYFIP1 | 5690082 | 17952 | -2.374 | -0.0747 | No | ||
182 | ICK | 1580746 3140021 | 18048 | -2.543 | -0.0610 | No | ||
183 | XPOT | 7050184 | 18063 | -2.580 | -0.0427 | No | ||
184 | EIF4G1 | 4070446 | 18120 | -2.717 | -0.0256 | No | ||
185 | TRIM8 | 6130441 | 18163 | -2.806 | -0.0072 | No | ||
186 | SRPK2 | 6380341 | 18529 | -4.282 | 0.0047 | No |