Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
Upregulated in class | truncNotch |
GeneSet | V$AP1_01 |
Enrichment Score (ES) | 0.41521576 |
Normalized Enrichment Score (NES) | 1.2215273 |
Nominal p-value | 0.050675675 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | ALDOA | 6290672 | 20 | 5.593 | 0.0373 | Yes | ||
2 | GNGT2 | 540176 | 50 | 4.702 | 0.0680 | Yes | ||
3 | POLD4 | 2320082 | 63 | 4.501 | 0.0982 | Yes | ||
4 | ABCB6 | 6350138 | 135 | 3.862 | 0.1208 | Yes | ||
5 | GPSM3 | 2690154 | 244 | 3.370 | 0.1381 | Yes | ||
6 | ABCD1 | 5670373 | 248 | 3.366 | 0.1610 | Yes | ||
7 | ALS2CR2 | 6450128 7100092 | 355 | 3.052 | 0.1762 | Yes | ||
8 | ABCA2 | 5050039 | 385 | 2.965 | 0.1949 | Yes | ||
9 | LMNA | 520471 1500075 3190167 4210020 | 594 | 2.565 | 0.2013 | Yes | ||
10 | PPP1R9B | 3130619 | 599 | 2.558 | 0.2186 | Yes | ||
11 | ENO1 | 5340128 | 621 | 2.530 | 0.2348 | Yes | ||
12 | HDAC3 | 4060072 | 777 | 2.296 | 0.2421 | Yes | ||
13 | SQSTM1 | 6550056 | 884 | 2.162 | 0.2512 | Yes | ||
14 | RAB3D | 4210253 | 915 | 2.109 | 0.2641 | Yes | ||
15 | ABCF3 | 7100100 | 940 | 2.081 | 0.2770 | Yes | ||
16 | FBS1 | 2570520 | 942 | 2.080 | 0.2912 | Yes | ||
17 | ROM1 | 3130685 | 978 | 2.044 | 0.3034 | Yes | ||
18 | ADCK4 | 1660180 | 1033 | 1.985 | 0.3141 | Yes | ||
19 | NCDN | 50040 1980739 3520603 | 1097 | 1.916 | 0.3238 | Yes | ||
20 | VAT1 | 1050040 | 1308 | 1.732 | 0.3243 | Yes | ||
21 | TNFRSF12A | 4810253 | 1329 | 1.716 | 0.3349 | Yes | ||
22 | DCTN2 | 540471 3780717 | 1404 | 1.640 | 0.3422 | Yes | ||
23 | TAGLN2 | 4560121 | 1433 | 1.619 | 0.3518 | Yes | ||
24 | BAG2 | 2900324 | 1539 | 1.540 | 0.3566 | Yes | ||
25 | TGFBR2 | 1780711 1980537 6550398 | 1564 | 1.525 | 0.3658 | Yes | ||
26 | CLIC1 | 110600 | 1679 | 1.464 | 0.3696 | Yes | ||
27 | ABHD4 | 6760450 | 1687 | 1.462 | 0.3793 | Yes | ||
28 | CCL27 | 2120070 | 1711 | 1.445 | 0.3880 | Yes | ||
29 | VASP | 7050500 | 1785 | 1.374 | 0.3934 | Yes | ||
30 | SERTAD1 | 2680332 | 1805 | 1.348 | 0.4016 | Yes | ||
31 | RIT1 | 5390338 | 1999 | 1.206 | 0.3994 | Yes | ||
32 | HSPB8 | 540563 | 2061 | 1.166 | 0.4041 | Yes | ||
33 | PPP2R5B | 2900441 | 2080 | 1.151 | 0.4110 | Yes | ||
34 | PADI4 | 1740075 4810441 | 2336 | 1.002 | 0.4041 | Yes | ||
35 | BAZ2A | 730184 | 2418 | 0.958 | 0.4063 | Yes | ||
36 | DTX2 | 4210041 7000008 | 2426 | 0.950 | 0.4124 | Yes | ||
37 | SLC11A1 | 940286 2810435 6370647 | 2562 | 0.870 | 0.4110 | Yes | ||
38 | EEF1A1 | 1980193 1990195 4670735 | 2634 | 0.835 | 0.4129 | Yes | ||
39 | ARHGAP8 | 380333 5390487 | 2694 | 0.803 | 0.4152 | Yes | ||
40 | PSMD2 | 4670706 5050364 | 2859 | 0.711 | 0.4112 | No | ||
41 | GABARAPL1 | 2810458 | 2934 | 0.678 | 0.4118 | No | ||
42 | GSTP1 | 3170102 3710707 5080368 | 2967 | 0.665 | 0.4147 | No | ||
43 | CDH23 | 4250242 5290397 6550397 | 3213 | 0.570 | 0.4053 | No | ||
44 | MDFI | 6200041 | 3273 | 0.546 | 0.4058 | No | ||
45 | DUSP14 | 1230358 | 3340 | 0.526 | 0.4058 | No | ||
46 | DUSP13 | 6400152 | 3397 | 0.508 | 0.4063 | No | ||
47 | ADRA1A | 1230446 2260390 | 3399 | 0.507 | 0.4097 | No | ||
48 | SLC38A3 | 5340142 | 3712 | 0.415 | 0.3956 | No | ||
49 | EPHA2 | 5890056 | 3762 | 0.403 | 0.3957 | No | ||
50 | TUBB4 | 5310681 | 3797 | 0.395 | 0.3966 | No | ||
51 | MMRN2 | 1740047 | 3843 | 0.386 | 0.3968 | No | ||
52 | PTPRR | 130121 3990273 | 3939 | 0.365 | 0.3941 | No | ||
53 | GADD45A | 2900717 | 4034 | 0.346 | 0.3914 | No | ||
54 | MRGPRF | 4780746 | 4064 | 0.341 | 0.3922 | No | ||
55 | RPS20 | 1740092 | 4185 | 0.320 | 0.3879 | No | ||
56 | HCN3 | 3940438 6840750 | 4223 | 0.314 | 0.3880 | No | ||
57 | RB1CC1 | 510494 7100072 | 4312 | 0.298 | 0.3853 | No | ||
58 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 4342 | 0.293 | 0.3857 | No | ||
59 | IRAK1 | 4120593 | 4606 | 0.252 | 0.3732 | No | ||
60 | LY6D | 4050010 | 4622 | 0.250 | 0.3741 | No | ||
61 | NRIP3 | 1340372 | 4705 | 0.240 | 0.3713 | No | ||
62 | CSMD3 | 1660427 1940687 | 5010 | 0.206 | 0.3562 | No | ||
63 | PIM1 | 630047 | 5122 | 0.191 | 0.3515 | No | ||
64 | ELAVL2 | 360181 | 5502 | 0.159 | 0.3320 | No | ||
65 | DIRAS1 | 2640270 | 5624 | 0.150 | 0.3265 | No | ||
66 | EEF1A2 | 2260162 5290086 | 5865 | 0.134 | 0.3143 | No | ||
67 | PVALB | 5570450 | 5970 | 0.126 | 0.3096 | No | ||
68 | STX17 | 2260037 | 6012 | 0.123 | 0.3082 | No | ||
69 | ST18 | 5720537 | 6045 | 0.121 | 0.3073 | No | ||
70 | GDNF | 4050487 5720739 | 6571 | 0.094 | 0.2794 | No | ||
71 | LRP1B | 1450193 | 6572 | 0.094 | 0.2801 | No | ||
72 | MMP7 | 1780497 | 6700 | 0.089 | 0.2738 | No | ||
73 | TLL1 | 2680315 | 6920 | 0.081 | 0.2625 | No | ||
74 | SV2B | 3850717 | 6982 | 0.078 | 0.2597 | No | ||
75 | FGF9 | 1050195 | 7035 | 0.077 | 0.2574 | No | ||
76 | COL5A3 | 1940471 | 7126 | 0.074 | 0.2530 | No | ||
77 | OLR1 | 50025 3840484 | 7141 | 0.073 | 0.2528 | No | ||
78 | MAPK12 | 450022 1340717 7050484 | 7315 | 0.068 | 0.2438 | No | ||
79 | ITGAX | 6130524 | 7373 | 0.065 | 0.2412 | No | ||
80 | ANGPT1 | 3990368 5130288 6770035 | 7423 | 0.064 | 0.2390 | No | ||
81 | FGF12 | 1740446 2360037 | 7431 | 0.064 | 0.2390 | No | ||
82 | DHRS3 | 360609 | 7456 | 0.063 | 0.2382 | No | ||
83 | AQP5 | 3830451 | 7597 | 0.059 | 0.2310 | No | ||
84 | SCEL | 3190129 | 7641 | 0.058 | 0.2290 | No | ||
85 | TRIB1 | 2320435 | 7647 | 0.058 | 0.2292 | No | ||
86 | EIF3S1 | 6130368 6770044 | 7791 | 0.055 | 0.2218 | No | ||
87 | COL7A1 | 1230168 2190072 | 7886 | 0.053 | 0.2170 | No | ||
88 | SNCG | 3120725 | 8070 | 0.049 | 0.2074 | No | ||
89 | CHST4 | 1190008 | 8127 | 0.047 | 0.2047 | No | ||
90 | DMD | 1740041 3990332 | 8227 | 0.045 | 0.1997 | No | ||
91 | ULK1 | 6100315 | 8269 | 0.044 | 0.1977 | No | ||
92 | FOSL1 | 430021 | 8299 | 0.043 | 0.1965 | No | ||
93 | SPATS2 | 2360066 | 8545 | 0.039 | 0.1834 | No | ||
94 | TAC1 | 7000195 380706 | 8632 | 0.037 | 0.1790 | No | ||
95 | TIAL1 | 4150048 6510605 | 8663 | 0.036 | 0.1776 | No | ||
96 | GFAP | 2060092 | 8686 | 0.035 | 0.1767 | No | ||
97 | EYA1 | 1450278 5220390 | 8781 | 0.033 | 0.1718 | No | ||
98 | P2RXL1 | 4730390 5220446 | 9139 | 0.026 | 0.1526 | No | ||
99 | IGSF9 | 1770411 | 9167 | 0.025 | 0.1513 | No | ||
100 | PSMD11 | 2340538 6510053 | 9169 | 0.025 | 0.1514 | No | ||
101 | CSF3 | 2230193 6660707 | 9341 | 0.022 | 0.1423 | No | ||
102 | CPNE8 | 7040039 | 9374 | 0.022 | 0.1407 | No | ||
103 | SFTPC | 3290133 | 9407 | 0.021 | 0.1391 | No | ||
104 | PSMA3 | 5900047 7040161 | 9538 | 0.019 | 0.1322 | No | ||
105 | ANXA7 | 6110446 | 9595 | 0.018 | 0.1293 | No | ||
106 | TNXB | 630592 3830020 5360497 7000673 | 9668 | 0.017 | 0.1255 | No | ||
107 | LENEP | 4850369 | 9814 | 0.014 | 0.1177 | No | ||
108 | SYT2 | 60609 | 9843 | 0.014 | 0.1163 | No | ||
109 | SMPX | 6590440 | 9958 | 0.012 | 0.1102 | No | ||
110 | RBP4 | 4540131 | 10193 | 0.008 | 0.0976 | No | ||
111 | BNIP3 | 3140270 | 10417 | 0.004 | 0.0855 | No | ||
112 | SHC3 | 2690398 | 10481 | 0.003 | 0.0821 | No | ||
113 | PHLDA2 | 4810494 | 10607 | 0.001 | 0.0753 | No | ||
114 | MAPRE3 | 7050504 | 10649 | 0.000 | 0.0731 | No | ||
115 | IL11 | 1740398 | 10880 | -0.003 | 0.0606 | No | ||
116 | TRPV3 | 540341 | 10957 | -0.005 | 0.0565 | No | ||
117 | SH3RF2 | 6200600 | 11409 | -0.013 | 0.0322 | No | ||
118 | HS6ST2 | 520133 5550603 | 11570 | -0.016 | 0.0236 | No | ||
119 | USP13 | 1450670 | 11797 | -0.020 | 0.0115 | No | ||
120 | SLC35E4 | 2370711 | 11810 | -0.020 | 0.0109 | No | ||
121 | OMG | 6760066 | 11946 | -0.023 | 0.0038 | No | ||
122 | MYOZ2 | 1050253 | 12053 | -0.026 | -0.0018 | No | ||
123 | ASB5 | 2760575 | 12420 | -0.034 | -0.0214 | No | ||
124 | MYB | 1660494 5860451 6130706 | 12609 | -0.039 | -0.0314 | No | ||
125 | PLCD1 | 2030484 | 12794 | -0.044 | -0.0410 | No | ||
126 | NUDT11 | 3840239 | 12846 | -0.046 | -0.0435 | No | ||
127 | SYNGR1 | 5130452 6650056 | 12879 | -0.047 | -0.0449 | No | ||
128 | PTPRN | 5900577 | 12891 | -0.048 | -0.0452 | No | ||
129 | IVL | 4560500 | 13187 | -0.057 | -0.0608 | No | ||
130 | SNCB | 3360133 | 13189 | -0.057 | -0.0605 | No | ||
131 | ATP6V1C2 | 6620092 | 13365 | -0.065 | -0.0695 | No | ||
132 | SERPINB5 | 6940050 | 13406 | -0.066 | -0.0712 | No | ||
133 | CALB2 | 6130170 6590368 | 13440 | -0.068 | -0.0726 | No | ||
134 | SLC26A1 | 2190142 | 13573 | -0.075 | -0.0792 | No | ||
135 | IL6 | 380133 | 13663 | -0.080 | -0.0835 | No | ||
136 | PFTK1 | 1780181 | 13767 | -0.086 | -0.0885 | No | ||
137 | ATP6V0D2 | 7050541 | 13817 | -0.090 | -0.0905 | No | ||
138 | CMYA1 | 6900632 | 13891 | -0.095 | -0.0938 | No | ||
139 | AKT3 | 1580270 3290278 | 13982 | -0.102 | -0.0980 | No | ||
140 | KCNA2 | 5080403 | 14027 | -0.105 | -0.0997 | No | ||
141 | MARK1 | 450484 | 14055 | -0.108 | -0.1004 | No | ||
142 | WASF2 | 4850592 | 14136 | -0.115 | -0.1040 | No | ||
143 | SSH2 | 360056 | 14301 | -0.133 | -0.1120 | No | ||
144 | IDS | 360619 5720161 | 14465 | -0.153 | -0.1198 | No | ||
145 | DTNA | 1340600 1780731 2340278 2850132 | 14597 | -0.174 | -0.1257 | No | ||
146 | LAMA3 | 1190131 5290239 | 14647 | -0.184 | -0.1271 | No | ||
147 | COL27A1 | 1740390 | 14752 | -0.205 | -0.1313 | No | ||
148 | NEK6 | 3360687 | 14798 | -0.213 | -0.1323 | No | ||
149 | CDKN1A | 4050088 6400706 | 14886 | -0.231 | -0.1354 | No | ||
150 | RNF34 | 3800332 4590717 5670138 | 14888 | -0.232 | -0.1339 | No | ||
151 | SLC22A18 | 7050168 | 14953 | -0.249 | -0.1357 | No | ||
152 | BACH1 | 290195 | 14954 | -0.249 | -0.1339 | No | ||
153 | APBA2BP | 5700341 | 14997 | -0.259 | -0.1344 | No | ||
154 | SPRED1 | 6940706 | 15086 | -0.286 | -0.1373 | No | ||
155 | NLK | 2030010 2450041 | 15117 | -0.295 | -0.1369 | No | ||
156 | SLC38A2 | 1470242 3800026 | 15153 | -0.306 | -0.1367 | No | ||
157 | PEA15 | 4590685 | 15176 | -0.313 | -0.1357 | No | ||
158 | TCF7 | 3800736 5390181 | 15277 | -0.346 | -0.1388 | No | ||
159 | VDR | 130156 510438 | 15287 | -0.348 | -0.1369 | No | ||
160 | LRRFIP2 | 670575 730152 6590438 | 15327 | -0.359 | -0.1365 | No | ||
161 | MCART1 | 5270059 | 15436 | -0.397 | -0.1397 | No | ||
162 | ABI3 | 1740563 | 15578 | -0.448 | -0.1442 | No | ||
163 | RIN1 | 510593 | 15763 | -0.520 | -0.1507 | No | ||
164 | HEPH | 2940176 3390040 6100195 6900575 7100170 | 15893 | -0.573 | -0.1537 | No | ||
165 | DLX1 | 360168 | 15974 | -0.614 | -0.1539 | No | ||
166 | UBXD3 | 5050193 | 16018 | -0.634 | -0.1518 | No | ||
167 | CMAS | 2190129 | 16136 | -0.688 | -0.1535 | No | ||
168 | APOBEC1 | 4610022 | 16329 | -0.801 | -0.1584 | No | ||
169 | GTF2B | 6860685 | 16353 | -0.810 | -0.1541 | No | ||
170 | TBXAS1 | 5050053 6900286 | 16388 | -0.834 | -0.1502 | No | ||
171 | LAMC1 | 4730025 | 16521 | -0.908 | -0.1512 | No | ||
172 | TRAF3 | 5690647 | 16573 | -0.943 | -0.1474 | No | ||
173 | BTK | 3130044 | 16802 | -1.068 | -0.1525 | No | ||
174 | MECP2 | 1940450 | 16813 | -1.075 | -0.1457 | No | ||
175 | GADD45G | 2510142 | 16850 | -1.097 | -0.1401 | No | ||
176 | YWHAG | 3780341 | 17025 | -1.251 | -0.1410 | No | ||
177 | EMP3 | 1500722 1570039 | 17068 | -1.293 | -0.1344 | No | ||
178 | RBBP7 | 430113 450450 2370309 | 17109 | -1.334 | -0.1274 | No | ||
179 | HSD3B7 | 1410129 | 17126 | -1.356 | -0.1190 | No | ||
180 | MAPK10 | 6110193 | 17369 | -1.612 | -0.1210 | No | ||
181 | PSMD12 | 730044 | 17438 | -1.690 | -0.1131 | No | ||
182 | SNX10 | 3800035 | 17446 | -1.695 | -0.1019 | No | ||
183 | VCL | 4120487 | 17715 | -2.044 | -0.1024 | No | ||
184 | PSMD7 | 2030619 6220594 | 17919 | -2.328 | -0.0975 | No | ||
185 | ICK | 1580746 3140021 | 18048 | -2.543 | -0.0870 | No | ||
186 | ATP1B1 | 3130594 | 18138 | -2.762 | -0.0728 | No | ||
187 | LUC7L | 6040156 6110411 | 18294 | -3.137 | -0.0597 | No | ||
188 | NEDD4L | 6380368 | 18321 | -3.241 | -0.0389 | No | ||
189 | VAPA | 2480594 | 18480 | -3.924 | -0.0206 | No | ||
190 | PPP2CA | 3990113 | 18501 | -4.067 | 0.0062 | No |