Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
Upregulated in class | truncNotch |
GeneSet | STTTCRNTTT_V$IRF_Q6 |
Enrichment Score (ES) | 0.47607878 |
Normalized Enrichment Score (NES) | 1.3449104 |
Nominal p-value | 0.022617124 |
FDR q-value | 0.97464854 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | HIP1R | 3120368 | 0 | 7.013 | 0.0573 | Yes | ||
2 | PSMB10 | 630504 6510039 | 81 | 4.302 | 0.0881 | Yes | ||
3 | LGALS3BP | 840692 | 82 | 4.289 | 0.1232 | Yes | ||
4 | TCIRG1 | 4590524 5910079 6900619 | 130 | 3.880 | 0.1524 | Yes | ||
5 | TAP1 | 4050047 | 167 | 3.645 | 0.1802 | Yes | ||
6 | UBE1L | 6660242 | 178 | 3.600 | 0.2091 | Yes | ||
7 | PSMB9 | 6980471 | 212 | 3.473 | 0.2357 | Yes | ||
8 | TAPBP | 1980110 | 231 | 3.409 | 0.2626 | Yes | ||
9 | VAMP5 | 3830300 | 269 | 3.288 | 0.2874 | Yes | ||
10 | GSDMDC1 | 4010092 5050091 | 286 | 3.240 | 0.3130 | Yes | ||
11 | SLC12A7 | 6860079 | 458 | 2.787 | 0.3266 | Yes | ||
12 | PSMB8 | 2850707 | 459 | 2.786 | 0.3493 | Yes | ||
13 | MRPS18B | 5570086 | 522 | 2.671 | 0.3678 | Yes | ||
14 | RNF31 | 110035 | 688 | 2.431 | 0.3787 | Yes | ||
15 | EIF5A | 1500059 5290022 6370026 | 896 | 2.143 | 0.3850 | Yes | ||
16 | EVL | 1740113 | 1037 | 1.979 | 0.3936 | Yes | ||
17 | ITGB7 | 4670619 | 1187 | 1.843 | 0.4006 | Yes | ||
18 | PIGR | 6520441 | 1274 | 1.759 | 0.4104 | Yes | ||
19 | IL12RB1 | 2230338 5420053 | 1336 | 1.710 | 0.4210 | Yes | ||
20 | ETV6 | 610524 | 1466 | 1.594 | 0.4271 | Yes | ||
21 | PSME2 | 4850086 | 1673 | 1.466 | 0.4279 | Yes | ||
22 | BAT5 | 5720687 | 1734 | 1.422 | 0.4363 | Yes | ||
23 | NFATC1 | 510400 2320348 4050600 6180161 6290136 6620086 | 1737 | 1.420 | 0.4478 | Yes | ||
24 | MAP3K11 | 7000039 | 1887 | 1.287 | 0.4502 | Yes | ||
25 | COL4A2 | 2350619 | 2109 | 1.138 | 0.4476 | Yes | ||
26 | CASP7 | 4210156 | 2149 | 1.104 | 0.4545 | Yes | ||
27 | MOV10 | 50673 430577 3870280 | 2291 | 1.024 | 0.4552 | Yes | ||
28 | PSME1 | 450193 4480035 | 2296 | 1.022 | 0.4634 | Yes | ||
29 | MSC | 5080139 | 2321 | 1.011 | 0.4703 | Yes | ||
30 | RPL23 | 2260452 4850435 6450673 | 2365 | 0.990 | 0.4761 | Yes | ||
31 | IGFBP5 | 2360592 | 2943 | 0.674 | 0.4504 | No | ||
32 | MLLT3 | 510204 3850722 6200088 | 3124 | 0.601 | 0.4455 | No | ||
33 | PSMA5 | 5390537 | 3139 | 0.596 | 0.4497 | No | ||
34 | MXI1 | 5050064 5130484 | 3155 | 0.590 | 0.4537 | No | ||
35 | GRAP2 | 7100441 1410647 | 3499 | 0.469 | 0.4389 | No | ||
36 | CDKN2C | 5050750 5130148 | 3520 | 0.464 | 0.4417 | No | ||
37 | CCND1 | 460524 770309 3120576 6980398 | 3689 | 0.419 | 0.4360 | No | ||
38 | COL4A1 | 1740575 | 3725 | 0.411 | 0.4375 | No | ||
39 | ECM2 | 1470561 | 3831 | 0.389 | 0.4350 | No | ||
40 | BCL11A | 6860369 | 3999 | 0.352 | 0.4288 | No | ||
41 | KCNE4 | 2470102 | 4587 | 0.255 | 0.3991 | No | ||
42 | TRPM3 | 2470110 6400731 6550047 | 4667 | 0.245 | 0.3969 | No | ||
43 | SOX5 | 2370576 2900167 3190128 5050528 | 5110 | 0.192 | 0.3745 | No | ||
44 | IL4 | 6020537 | 5279 | 0.177 | 0.3669 | No | ||
45 | WNT5A | 840685 3120152 | 5340 | 0.171 | 0.3650 | No | ||
46 | LGP2 | 4480338 | 5595 | 0.152 | 0.3525 | No | ||
47 | LIF | 1410373 2060129 3990338 | 6027 | 0.122 | 0.3302 | No | ||
48 | USF1 | 4280156 4610114 6370113 | 6065 | 0.121 | 0.3292 | No | ||
49 | DLX4 | 50215 6650059 | 6307 | 0.107 | 0.3170 | No | ||
50 | SLC25A28 | 6590600 | 6409 | 0.101 | 0.3124 | No | ||
51 | EGFL6 | 3940181 | 6466 | 0.099 | 0.3102 | No | ||
52 | HOXB6 | 4210739 | 6477 | 0.099 | 0.3104 | No | ||
53 | LRP2 | 1400204 3290706 | 6502 | 0.097 | 0.3099 | No | ||
54 | IL17RC | 630164 2810593 | 7080 | 0.075 | 0.2793 | No | ||
55 | SLC15A3 | 6650333 | 7204 | 0.071 | 0.2732 | No | ||
56 | PITX2 | 870537 2690139 | 7472 | 0.063 | 0.2593 | No | ||
57 | TNFSF13B | 1940438 6510441 | 7528 | 0.061 | 0.2568 | No | ||
58 | DDR2 | 7050273 | 7929 | 0.052 | 0.2356 | No | ||
59 | MSX1 | 2650309 | 7991 | 0.050 | 0.2327 | No | ||
60 | CHGB | 1980053 | 8278 | 0.044 | 0.2176 | No | ||
61 | BHLHB3 | 3450438 | 8505 | 0.039 | 0.2057 | No | ||
62 | NRG1 | 1050332 | 8525 | 0.039 | 0.2050 | No | ||
63 | IL27 | 1990324 | 8541 | 0.039 | 0.2045 | No | ||
64 | CPT1A | 6350093 | 8589 | 0.038 | 0.2023 | No | ||
65 | FMR1 | 5050075 | 8594 | 0.037 | 0.2023 | No | ||
66 | CLDN3 | 2570524 | 8794 | 0.033 | 0.1918 | No | ||
67 | IFNB1 | 1400142 | 9172 | 0.025 | 0.1717 | No | ||
68 | ASPA | 3290400 | 9230 | 0.024 | 0.1688 | No | ||
69 | KLHL13 | 6590731 | 9475 | 0.020 | 0.1557 | No | ||
70 | CXCL10 | 2450408 | 9524 | 0.019 | 0.1533 | No | ||
71 | PSMA3 | 5900047 7040161 | 9538 | 0.019 | 0.1527 | No | ||
72 | LGI1 | 1850020 | 9561 | 0.019 | 0.1517 | No | ||
73 | HOXA13 | 3120647 | 9594 | 0.018 | 0.1501 | No | ||
74 | EDIL3 | 1240039 | 9701 | 0.016 | 0.1445 | No | ||
75 | INDO | 2680390 | 9825 | 0.014 | 0.1380 | No | ||
76 | SATB2 | 2470181 | 9856 | 0.014 | 0.1365 | No | ||
77 | ALDH1A1 | 6520706 | 9932 | 0.012 | 0.1325 | No | ||
78 | CBX4 | 70332 | 10054 | 0.010 | 0.1260 | No | ||
79 | TCF15 | 1690400 | 10299 | 0.006 | 0.1129 | No | ||
80 | OTX1 | 2510215 | 10412 | 0.004 | 0.1069 | No | ||
81 | KIRREL3 | 2630195 | 10727 | -0.001 | 0.0899 | No | ||
82 | NPR3 | 1580239 | 11102 | -0.007 | 0.0697 | No | ||
83 | OSR2 | 70711 | 11122 | -0.008 | 0.0687 | No | ||
84 | MEIS1 | 1400575 | 11236 | -0.010 | 0.0627 | No | ||
85 | PGM5 | 2340446 | 11636 | -0.017 | 0.0413 | No | ||
86 | HGF | 3360593 | 11676 | -0.018 | 0.0393 | No | ||
87 | PLXNC1 | 5860315 | 11982 | -0.024 | 0.0230 | No | ||
88 | GSH1 | 2760242 | 12148 | -0.028 | 0.0143 | No | ||
89 | GSC | 1580685 | 12276 | -0.030 | 0.0077 | No | ||
90 | ELK4 | 460494 940369 4480136 | 12315 | -0.032 | 0.0059 | No | ||
91 | ARHGAP5 | 2510619 3360035 | 12579 | -0.038 | -0.0081 | No | ||
92 | UBD | 5570632 | 12731 | -0.043 | -0.0159 | No | ||
93 | BCOR | 1660452 3940053 | 12768 | -0.044 | -0.0175 | No | ||
94 | MAB21L1 | 1450634 1580092 | 12805 | -0.045 | -0.0190 | No | ||
95 | IL22RA1 | 5720603 | 12844 | -0.046 | -0.0207 | No | ||
96 | HPCAL1 | 1980129 2350348 | 12909 | -0.048 | -0.0238 | No | ||
97 | NCF1 | 3850091 | 13282 | -0.061 | -0.0434 | No | ||
98 | ESR1 | 4060372 5860193 | 13327 | -0.063 | -0.0453 | No | ||
99 | NR3C2 | 2480324 6400093 | 13771 | -0.086 | -0.0686 | No | ||
100 | PBEF1 | 1090278 | 13793 | -0.088 | -0.0690 | No | ||
101 | PPARGC1A | 4670040 | 14233 | -0.125 | -0.0917 | No | ||
102 | THRAP1 | 2470121 | 14284 | -0.131 | -0.0933 | No | ||
103 | MGAT4A | 5690471 | 14443 | -0.151 | -0.1007 | No | ||
104 | CDK6 | 4920253 | 14861 | -0.226 | -0.1214 | No | ||
105 | GATA6 | 1770010 | 14869 | -0.228 | -0.1199 | No | ||
106 | ZBP1 | 4210138 | 14940 | -0.246 | -0.1217 | No | ||
107 | CREB1 | 1500717 2230358 3610600 6550601 | 15202 | -0.323 | -0.1331 | No | ||
108 | E2F3 | 50162 460180 | 15296 | -0.350 | -0.1353 | No | ||
109 | CITED2 | 5670114 5130088 | 15380 | -0.379 | -0.1367 | No | ||
110 | PPP1R10 | 110136 3170725 3610484 | 15533 | -0.430 | -0.1414 | No | ||
111 | NEDD4 | 460736 1190280 | 15556 | -0.438 | -0.1390 | No | ||
112 | PHF15 | 6550066 6860673 | 15765 | -0.521 | -0.1460 | No | ||
113 | BCL2L1 | 1580452 4200152 5420484 | 15795 | -0.530 | -0.1433 | No | ||
114 | ADAM12 | 3390132 4070347 | 15796 | -0.531 | -0.1389 | No | ||
115 | BST2 | 6760487 | 15817 | -0.541 | -0.1356 | No | ||
116 | IFIT2 | 4810735 | 15858 | -0.558 | -0.1332 | No | ||
117 | ARHGEF6 | 4780164 6380450 | 15929 | -0.589 | -0.1322 | No | ||
118 | CASP1 | 2360546 | 16152 | -0.700 | -0.1384 | No | ||
119 | DDX58 | 2450075 | 16385 | -0.831 | -0.1442 | No | ||
120 | ZDHHC14 | 3780458 | 16459 | -0.874 | -0.1410 | No | ||
121 | PSIP1 | 1780082 3190435 5050594 | 16655 | -0.985 | -0.1435 | No | ||
122 | B2M | 5080332 5130059 | 16688 | -1.000 | -0.1371 | No | ||
123 | VGLL4 | 6860463 | 16861 | -1.106 | -0.1373 | No | ||
124 | YWHAG | 3780341 | 17025 | -1.251 | -0.1359 | No | ||
125 | NT5C3 | 1570075 | 17088 | -1.312 | -0.1286 | No | ||
126 | IL18BP | 3450128 | 17117 | -1.342 | -0.1191 | No | ||
127 | NFIX | 2450152 | 17270 | -1.505 | -0.1150 | No | ||
128 | TCF12 | 3610324 7000156 | 17340 | -1.578 | -0.1059 | No | ||
129 | LRMP | 6290193 | 17439 | -1.692 | -0.0974 | No | ||
130 | SFMBT1 | 2360450 2370070 | 17640 | -1.918 | -0.0925 | No | ||
131 | USP18 | 4010110 | 17906 | -2.303 | -0.0880 | No | ||
132 | PIK3R3 | 1770333 | 18020 | -2.488 | -0.0738 | No | ||
133 | SFRS6 | 60224 | 18213 | -2.933 | -0.0602 | No | ||
134 | CHCHD1 | 110706 | 18277 | -3.088 | -0.0384 | No | ||
135 | PTK2 | 1780148 | 18615 | -6.937 | 0.0001 | No |