Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
Upregulated in class | absentNotch |
GeneSet | CAGTGTT,MIR-141,MIR-200A |
Enrichment Score (ES) | -0.6045514 |
Normalized Enrichment Score (NES) | -1.88331 |
Nominal p-value | 0.0 |
FDR q-value | 0.0017838151 |
FWER p-Value | 0.0050 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | STAT5A | 2680458 | 210 | 3.478 | 0.0068 | No | ||
2 | ACOT7 | 730735 1400176 7050053 | 241 | 3.382 | 0.0229 | No | ||
3 | PSEN1 | 130403 2030647 6100603 | 383 | 2.978 | 0.0308 | No | ||
4 | RTN4RL1 | 2630368 | 435 | 2.848 | 0.0429 | No | ||
5 | BACE1 | 2650438 | 1039 | 1.977 | 0.0205 | No | ||
6 | ST3GAL3 | 2810601 | 1594 | 1.509 | -0.0017 | No | ||
7 | EPN1 | 4060725 | 1599 | 1.507 | 0.0060 | No | ||
8 | SON | 3120148 5860239 7040403 | 1865 | 1.303 | -0.0016 | No | ||
9 | SLC25A3 | 670112 | 1884 | 1.291 | 0.0042 | No | ||
10 | SERF2 | 5720010 | 2053 | 1.169 | 0.0011 | No | ||
11 | ATF5 | 5670685 | 2075 | 1.156 | 0.0061 | No | ||
12 | HRBL | 1850102 3830253 4780176 | 2215 | 1.067 | 0.0041 | No | ||
13 | DEK | 1050451 4560037 | 2505 | 0.906 | -0.0069 | No | ||
14 | AMPD2 | 630093 1170070 | 2534 | 0.886 | -0.0038 | No | ||
15 | TOP1 | 770471 4060632 6650324 | 2641 | 0.831 | -0.0052 | No | ||
16 | MDM1 | 510528 1780280 2680152 2690181 3060025 3120487 4210601 4540037 4610142 5290110 6400433 6480743 | 2676 | 0.810 | -0.0028 | No | ||
17 | PPT2 | 2340059 3450148 | 2719 | 0.789 | -0.0009 | No | ||
18 | PPP2R2A | 2900014 5700575 | 2726 | 0.786 | 0.0029 | No | ||
19 | HMG20A | 4590113 | 2924 | 0.680 | -0.0043 | No | ||
20 | CDC42BPB | 6350037 | 3106 | 0.605 | -0.0110 | No | ||
21 | DLC1 | 1090632 6450594 | 3366 | 0.516 | -0.0223 | No | ||
22 | LRRC8A | 2510193 | 3525 | 0.463 | -0.0285 | No | ||
23 | TSC1 | 1850672 | 3536 | 0.461 | -0.0266 | No | ||
24 | DOLPP1 | 4780619 6400053 | 3553 | 0.457 | -0.0251 | No | ||
25 | MOBKL2B | 940128 | 3617 | 0.436 | -0.0263 | No | ||
26 | SPRYD3 | 50403 | 3626 | 0.435 | -0.0244 | No | ||
27 | PEX5 | 1240746 1570092 2510487 | 3627 | 0.435 | -0.0221 | No | ||
28 | SIPA1L2 | 4850731 | 3645 | 0.431 | -0.0208 | No | ||
29 | HIC2 | 4010433 | 3701 | 0.418 | -0.0216 | No | ||
30 | EPHA2 | 5890056 | 3762 | 0.403 | -0.0228 | No | ||
31 | PAPPA | 4230463 | 3954 | 0.361 | -0.0313 | No | ||
32 | SEMA6A | 2690138 3060021 | 3958 | 0.359 | -0.0295 | No | ||
33 | SLC6A9 | 2470520 | 3974 | 0.358 | -0.0285 | No | ||
34 | SYT4 | 5080193 | 3989 | 0.355 | -0.0274 | No | ||
35 | KIF1C | 2480484 | 4060 | 0.341 | -0.0294 | No | ||
36 | ZCCHC3 | 580438 1990035 4780278 | 4268 | 0.306 | -0.0391 | No | ||
37 | TM9SF4 | 450538 1050093 4210112 | 4616 | 0.251 | -0.0566 | No | ||
38 | TTYH2 | 1450397 3870100 6550347 | 4638 | 0.249 | -0.0564 | No | ||
39 | PTPRG | 2650524 1340022 | 4734 | 0.237 | -0.0604 | No | ||
40 | STAT5B | 6200026 | 4979 | 0.210 | -0.0725 | No | ||
41 | PLAG1 | 1450142 3870139 6520039 | 5097 | 0.194 | -0.0779 | No | ||
42 | SOX5 | 2370576 2900167 3190128 5050528 | 5110 | 0.192 | -0.0775 | No | ||
43 | MDGA1 | 1170139 | 5276 | 0.177 | -0.0856 | No | ||
44 | CYP26B1 | 2630142 | 5297 | 0.175 | -0.0857 | No | ||
45 | ELF2 | 1690014 2480132 3060180 3190504 | 5320 | 0.173 | -0.0860 | No | ||
46 | EPHA7 | 1190288 4010278 | 5394 | 0.167 | -0.0891 | No | ||
47 | ELAVL2 | 360181 | 5502 | 0.159 | -0.0941 | No | ||
48 | RAB38 | 2970735 | 5890 | 0.131 | -0.1145 | No | ||
49 | USP9X | 130435 2370735 3120338 | 5935 | 0.128 | -0.1162 | No | ||
50 | CXCL12 | 580546 4150750 4570068 | 5956 | 0.127 | -0.1166 | No | ||
51 | SLC17A6 | 4210576 | 6026 | 0.122 | -0.1197 | No | ||
52 | CPD | 5360403 5860685 | 6138 | 0.116 | -0.1252 | No | ||
53 | HOXB5 | 2900538 | 6179 | 0.114 | -0.1267 | No | ||
54 | FRMD4A | 2190176 | 6232 | 0.111 | -0.1290 | No | ||
55 | ATXN1 | 5550156 | 6268 | 0.109 | -0.1303 | No | ||
56 | LHX6 | 2360731 3360397 | 6473 | 0.099 | -0.1409 | No | ||
57 | MYT1L | 5670369 6660403 | 6775 | 0.086 | -0.1568 | No | ||
58 | KLHL18 | 4560075 | 6783 | 0.086 | -0.1567 | No | ||
59 | BRUNOL6 | 6840373 | 6915 | 0.081 | -0.1634 | No | ||
60 | PHLPP | 3440563 | 6987 | 0.078 | -0.1669 | No | ||
61 | NRP2 | 4070400 5860041 6650446 | 7011 | 0.077 | -0.1677 | No | ||
62 | STK35 | 2360121 | 7089 | 0.075 | -0.1715 | No | ||
63 | PHYHIPL | 2360706 3840692 | 7219 | 0.071 | -0.1782 | No | ||
64 | POU4F1 | 2260315 | 7281 | 0.069 | -0.1811 | No | ||
65 | STAT4 | 1660373 3130019 | 7387 | 0.065 | -0.1865 | No | ||
66 | PITX2 | 870537 2690139 | 7472 | 0.063 | -0.1907 | No | ||
67 | TMEFF1 | 2680100 | 7521 | 0.061 | -0.1930 | No | ||
68 | HOXC13 | 4070722 | 8062 | 0.049 | -0.2221 | No | ||
69 | DIXDC1 | 6980435 | 8235 | 0.045 | -0.2312 | No | ||
70 | KHDRBS2 | 3520717 | 8364 | 0.042 | -0.2380 | No | ||
71 | ACVR2A | 6110647 | 8377 | 0.042 | -0.2384 | No | ||
72 | TIAL1 | 4150048 6510605 | 8663 | 0.036 | -0.2537 | No | ||
73 | LPP | 1660541 | 8726 | 0.034 | -0.2569 | No | ||
74 | NFASC | 1940619 2470156 4590168 6840524 | 8737 | 0.034 | -0.2573 | No | ||
75 | WDFY3 | 3610041 4560333 4570273 | 8747 | 0.034 | -0.2576 | No | ||
76 | FOXA1 | 3710609 | 8791 | 0.033 | -0.2598 | No | ||
77 | HLF | 2370113 | 8873 | 0.031 | -0.2640 | No | ||
78 | PAFAH1B2 | 5360546 6860672 | 9192 | 0.025 | -0.2812 | No | ||
79 | CSF3 | 2230193 6660707 | 9341 | 0.022 | -0.2891 | No | ||
80 | ITSN1 | 2640577 | 9376 | 0.022 | -0.2908 | No | ||
81 | MTSS1 | 780435 2370114 | 9419 | 0.021 | -0.2930 | No | ||
82 | RARB | 430139 1410138 | 9596 | 0.018 | -0.3025 | No | ||
83 | THRB | 1780673 | 9619 | 0.017 | -0.3036 | No | ||
84 | CHES1 | 4570121 5700162 | 9623 | 0.017 | -0.3036 | No | ||
85 | LYPLA1 | 4480373 5570551 | 9799 | 0.015 | -0.3131 | No | ||
86 | TRHDE | 1690068 | 9802 | 0.015 | -0.3131 | No | ||
87 | GPM6B | 6220458 | 9946 | 0.012 | -0.3208 | No | ||
88 | PCDH8 | 2360047 4200452 | 10056 | 0.010 | -0.3267 | No | ||
89 | SPG3A | 2760091 3120170 | 10227 | 0.008 | -0.3359 | No | ||
90 | HOXA11 | 6980133 | 10253 | 0.007 | -0.3372 | No | ||
91 | DDX5 | 940021 2630338 3440148 | 10257 | 0.007 | -0.3373 | No | ||
92 | B3GNT1 | 2350446 | 10264 | 0.007 | -0.3376 | No | ||
93 | MMP16 | 2680139 | 10266 | 0.007 | -0.3377 | No | ||
94 | SP4 | 3850176 | 10522 | 0.002 | -0.3515 | No | ||
95 | TTR | 4150072 | 10531 | 0.002 | -0.3519 | No | ||
96 | ZFR | 5910647 | 10559 | 0.002 | -0.3534 | No | ||
97 | LENG8 | 3130731 | 10636 | 0.001 | -0.3575 | No | ||
98 | PCTK2 | 5700673 | 10825 | -0.002 | -0.3677 | No | ||
99 | NRXN1 | 460408 5340270 6370066 | 10844 | -0.003 | -0.3687 | No | ||
100 | SRC | 580132 | 10879 | -0.003 | -0.3705 | No | ||
101 | EXOC5 | 7000711 | 11008 | -0.006 | -0.3775 | No | ||
102 | CALCR | 1690494 | 11413 | -0.013 | -0.3994 | No | ||
103 | SNF1LK | 6110403 | 11552 | -0.016 | -0.4068 | No | ||
104 | CLASP2 | 2510139 | 11667 | -0.018 | -0.4129 | No | ||
105 | HNRPF | 670138 | 11877 | -0.022 | -0.4241 | No | ||
106 | SLC16A7 | 2320672 | 12147 | -0.028 | -0.4386 | No | ||
107 | DR1 | 5860750 | 12291 | -0.031 | -0.4462 | No | ||
108 | ARPC5 | 1740411 3450300 | 12360 | -0.033 | -0.4498 | No | ||
109 | DMWD | 770019 1690047 | 12376 | -0.033 | -0.4504 | No | ||
110 | TGFB2 | 4920292 | 12423 | -0.034 | -0.4527 | No | ||
111 | NR2C2 | 6100097 | 12454 | -0.035 | -0.4542 | No | ||
112 | OLFM1 | 3360161 5570066 | 12541 | -0.038 | -0.4586 | No | ||
113 | CSNK2A1 | 1580577 | 12809 | -0.045 | -0.4729 | No | ||
114 | SEPT7 | 2760685 | 12920 | -0.049 | -0.4787 | No | ||
115 | RBM7 | 5890348 | 12924 | -0.049 | -0.4786 | No | ||
116 | ESRRG | 4010181 | 12968 | -0.050 | -0.4806 | No | ||
117 | ATXN7 | 1450435 | 13269 | -0.061 | -0.4966 | No | ||
118 | RAD23B | 2190671 | 13382 | -0.065 | -0.5024 | No | ||
119 | MYRIP | 1580471 | 13410 | -0.066 | -0.5035 | No | ||
120 | QKI | 5220093 6130044 | 13451 | -0.068 | -0.5053 | No | ||
121 | KCNJ2 | 630019 | 13603 | -0.076 | -0.5131 | No | ||
122 | JUN | 840170 | 13623 | -0.077 | -0.5138 | No | ||
123 | WDR26 | 1090138 | 13671 | -0.080 | -0.5159 | No | ||
124 | UBE3A | 1240152 2690438 5860609 | 13746 | -0.084 | -0.5195 | No | ||
125 | PBEF1 | 1090278 | 13793 | -0.088 | -0.5215 | No | ||
126 | GRIN3A | 2370592 | 13813 | -0.089 | -0.5221 | No | ||
127 | DRD2 | 5890369 | 13903 | -0.096 | -0.5264 | No | ||
128 | STXBP1 | 360072 6220717 | 13948 | -0.099 | -0.5283 | No | ||
129 | STRN | 5570706 7050333 | 14103 | -0.112 | -0.5361 | No | ||
130 | DUSP3 | 1240129 6840215 | 14115 | -0.113 | -0.5361 | No | ||
131 | CSNK1A1 | 2340427 | 14138 | -0.115 | -0.5367 | No | ||
132 | PCDH9 | 2100136 | 14245 | -0.126 | -0.5418 | No | ||
133 | APBB2 | 5130403 | 14264 | -0.129 | -0.5421 | No | ||
134 | PTP4A1 | 130692 | 14273 | -0.130 | -0.5419 | No | ||
135 | SNAP91 | 3170056 5690520 | 14381 | -0.142 | -0.5469 | No | ||
136 | BAP1 | 3830131 | 14491 | -0.157 | -0.5520 | No | ||
137 | SPAG9 | 580497 2510180 4210685 | 14493 | -0.157 | -0.5513 | No | ||
138 | SLC1A1 | 520372 6420059 | 14777 | -0.210 | -0.5656 | No | ||
139 | GATA6 | 1770010 | 14869 | -0.228 | -0.5693 | No | ||
140 | RPH3AL | 70110 | 14902 | -0.237 | -0.5698 | No | ||
141 | FGFR2 | 4670601 5570402 6940377 | 15016 | -0.265 | -0.5746 | No | ||
142 | WDR44 | 130195 1050609 1570685 | 15051 | -0.276 | -0.5750 | No | ||
143 | SOX11 | 610279 | 15082 | -0.284 | -0.5751 | No | ||
144 | BICD2 | 1090411 | 15223 | -0.330 | -0.5810 | No | ||
145 | E2F3 | 50162 460180 | 15296 | -0.350 | -0.5831 | No | ||
146 | CNR1 | 6550494 6760497 | 15368 | -0.377 | -0.5850 | No | ||
147 | MARCH7 | 3800020 6620168 | 15392 | -0.383 | -0.5842 | No | ||
148 | CHD9 | 430037 2570129 5420398 | 15499 | -0.419 | -0.5878 | No | ||
149 | TAF12 | 3710746 4920300 6180603 | 15606 | -0.460 | -0.5911 | No | ||
150 | FBXL2 | 6450722 | 15679 | -0.484 | -0.5925 | No | ||
151 | YTHDF3 | 4540632 4670717 7040609 | 15750 | -0.515 | -0.5936 | No | ||
152 | TNS3 | 6380242 | 15764 | -0.520 | -0.5916 | No | ||
153 | THRAP2 | 4920600 | 15773 | -0.524 | -0.5893 | No | ||
154 | FKBP5 | 2190048 | 15866 | -0.562 | -0.5914 | No | ||
155 | TCERG1 | 2350551 4540397 5220746 | 15978 | -0.615 | -0.5942 | No | ||
156 | PTGES3 | 2190440 2680524 | 16170 | -0.709 | -0.6008 | Yes | ||
157 | MYH10 | 2640673 | 16190 | -0.718 | -0.5981 | Yes | ||
158 | ARHGEF18 | 2120279 | 16227 | -0.749 | -0.5961 | Yes | ||
159 | CALU | 2680403 3520056 4610348 5720176 6130121 | 16292 | -0.779 | -0.5955 | Yes | ||
160 | HIPK1 | 110193 | 16303 | -0.786 | -0.5920 | Yes | ||
161 | SLC39A9 | 3940348 | 16321 | -0.796 | -0.5887 | Yes | ||
162 | PLAGL2 | 1770148 | 16346 | -0.808 | -0.5858 | Yes | ||
163 | KPNA3 | 7040088 | 16389 | -0.834 | -0.5837 | Yes | ||
164 | BHLHB2 | 7040603 | 16464 | -0.878 | -0.5831 | Yes | ||
165 | CDC14A | 4050132 | 16473 | -0.881 | -0.5790 | Yes | ||
166 | FUS | 4760619 | 16558 | -0.935 | -0.5786 | Yes | ||
167 | ANKFY1 | 360309 5390021 | 16579 | -0.947 | -0.5748 | Yes | ||
168 | ACACA | 2490612 2680369 | 16594 | -0.954 | -0.5705 | Yes | ||
169 | PDCD4 | 3360403 5690110 | 16635 | -0.974 | -0.5676 | Yes | ||
170 | MECP2 | 1940450 | 16813 | -1.075 | -0.5716 | Yes | ||
171 | AK3L1 | 7100601 | 16837 | -1.087 | -0.5671 | Yes | ||
172 | OLIG3 | 1050603 | 16897 | -1.140 | -0.5644 | Yes | ||
173 | YWHAG | 3780341 | 17025 | -1.251 | -0.5647 | Yes | ||
174 | MBNL1 | 2640762 7100048 | 17040 | -1.263 | -0.5589 | Yes | ||
175 | ATP6V1B2 | 4060528 | 17047 | -1.268 | -0.5526 | Yes | ||
176 | TFRC | 4050551 | 17049 | -1.269 | -0.5460 | Yes | ||
177 | HOXB4 | 540131 | 17071 | -1.296 | -0.5403 | Yes | ||
178 | OGT | 2360131 4610333 | 17074 | -1.298 | -0.5337 | Yes | ||
179 | ARNTL | 3170463 | 17078 | -1.301 | -0.5270 | Yes | ||
180 | DNAJC13 | 4730091 | 17096 | -1.317 | -0.5210 | Yes | ||
181 | KIF3A | 5050348 6650079 | 17111 | -1.335 | -0.5148 | Yes | ||
182 | SIM2 | 2100044 | 17227 | -1.457 | -0.5134 | Yes | ||
183 | MIB1 | 3800537 | 17289 | -1.521 | -0.5088 | Yes | ||
184 | CSNK1G3 | 110450 | 17294 | -1.527 | -0.5010 | Yes | ||
185 | TCF12 | 3610324 7000156 | 17340 | -1.578 | -0.4952 | Yes | ||
186 | RTF1 | 2100735 | 17419 | -1.669 | -0.4907 | Yes | ||
187 | CDC25A | 3800184 | 17420 | -1.670 | -0.4819 | Yes | ||
188 | SIRT1 | 1190731 | 17426 | -1.676 | -0.4734 | Yes | ||
189 | APRIN | 2810050 | 17454 | -1.712 | -0.4659 | Yes | ||
190 | TULP4 | 2320364 | 17496 | -1.755 | -0.4590 | Yes | ||
191 | SLC23A2 | 6660722 | 17533 | -1.795 | -0.4515 | Yes | ||
192 | CBL | 6380068 | 17537 | -1.799 | -0.4423 | Yes | ||
193 | FOXP1 | 6510433 | 17556 | -1.822 | -0.4337 | Yes | ||
194 | RUNX1 | 3840711 | 17573 | -1.837 | -0.4250 | Yes | ||
195 | CUL3 | 1850520 | 17579 | -1.848 | -0.4156 | Yes | ||
196 | GPC2 | 130647 | 17613 | -1.884 | -0.4075 | Yes | ||
197 | GRB2 | 6650398 | 17634 | -1.909 | -0.3986 | Yes | ||
198 | RBMS1 | 6400014 | 17662 | -1.950 | -0.3898 | Yes | ||
199 | ATP2A2 | 1090075 3990279 | 17677 | -1.987 | -0.3802 | Yes | ||
200 | CDV3 | 1940577 | 17722 | -2.057 | -0.3718 | Yes | ||
201 | YAF2 | 940053 | 17726 | -2.061 | -0.3612 | Yes | ||
202 | SLC20A1 | 6420014 | 17761 | -2.104 | -0.3520 | Yes | ||
203 | PPP1R15B | 2640280 5860082 | 17799 | -2.153 | -0.3427 | Yes | ||
204 | YTHDF2 | 4060332 4610279 | 17844 | -2.212 | -0.3336 | Yes | ||
205 | BRD3 | 6130672 | 17874 | -2.246 | -0.3234 | Yes | ||
206 | H2AFZ | 1470168 | 17943 | -2.360 | -0.3147 | Yes | ||
207 | ATP6V1A | 6590242 | 17950 | -2.364 | -0.3027 | Yes | ||
208 | CNP | 2260451 | 17968 | -2.398 | -0.2910 | Yes | ||
209 | CCNE2 | 3120537 | 18087 | -2.639 | -0.2836 | Yes | ||
210 | MTPN | 3940167 | 18101 | -2.686 | -0.2703 | Yes | ||
211 | ATP1B1 | 3130594 | 18138 | -2.762 | -0.2578 | Yes | ||
212 | OSBPL11 | 1770044 | 18268 | -3.068 | -0.2487 | Yes | ||
213 | RABGAP1 | 5050397 | 18290 | -3.128 | -0.2335 | Yes | ||
214 | RNF44 | 5910692 | 18326 | -3.259 | -0.2183 | Yes | ||
215 | CD47 | 1850603 | 18346 | -3.343 | -0.2018 | Yes | ||
216 | RAP2C | 1690132 | 18365 | -3.418 | -0.1849 | Yes | ||
217 | SFPQ | 4760110 | 18381 | -3.477 | -0.1675 | Yes | ||
218 | TRAM1 | 2340441 6620592 | 18409 | -3.588 | -0.1502 | Yes | ||
219 | PITPNB | 5130039 | 18413 | -3.593 | -0.1315 | Yes | ||
220 | MAP2K4 | 5130133 | 18441 | -3.735 | -0.1134 | Yes | ||
221 | PPP2CA | 3990113 | 18501 | -4.067 | -0.0954 | Yes | ||
222 | SUPT6H | 3170082 | 18520 | -4.172 | -0.0745 | Yes | ||
223 | ANP32E | 6510706 | 18535 | -4.345 | -0.0525 | Yes | ||
224 | WSB1 | 870563 | 18569 | -4.783 | -0.0292 | Yes | ||
225 | PRKACB | 4210170 | 18607 | -6.062 | 0.0005 | Yes |